猪繁殖与呼吸综合征病毒经典株与变异株的分离鉴定及经典株灭活疫苗的研制
摘要
引文
[1]殷震,刘景华.动物病毒学[M].第二版.北京：科学出版社.1997
[2]Wensvoort G, de Kluyver EP, Pol JMA, et al. Lelystad virus, the cause of porcine epidemic abortionand respiratory syndrome:a review of mystery swine disease research at Lelystad. Vet Microbiol,1992
[3]Van Niienwstadt A.P., Meulenberg J.J.M., Van Essen-Zanbergen A., et al. Poteins encoded by open reading frames 3 and 4 of the genome of Lelystad virus (Arterviridae) are structural proteins of the virion J, Virol.70(1996):4767-4772
[4]Bautista E.M., Suarez P., Molitor W., et al. T cell responses to the structural polypeptides of porcinereproductive and respiratory syndrome virus, Arch.Virol.144(1999)117-134
[5]Wai-Hong.Wu, Yin Fang, Rachel Farwell, et al..A 10KU structure protein of PRRSV encoded by ORF2b. Virology 287,183-191(2001)
[6]Dea, s, Gagnon, C:A, Mardassi, H, Pirzadeh; B. and rogan, D.(2000)Current knowledge on the structural protein of prrsv; comparision of the north American and European isolates. arch virol 145659-688
[7]Conzelmann KK, Visser N, Van Woensel P, Thiel HJ(1993) Molecular charization of porcine reproductive and respiratory syndrome virus(PRRSV), a member of the arterirus group. Virology 193:329-339
[8]郭宝清,陈章水,刘文兴,等.从凝似PRRS流产胎儿分离PRRSV的研究[J].中国畜禽传染病.1996,(2)：1-4.
[9]Jusa ER, Inaba Y, Kouno M, et al Hemagglutination with porcine reproductive and respiratory syndrome virus[J]. J Vet Med Sci.1996,58:521-527
[10]陆承平.兽医微生物学(第四版)[M].北京：中国农业出版社,2007.443-445
[11]Morozov I, Meng X J, Paul P S.Sequence analysis of open readingframes(ORFs)2 to 4 of U.S.isolate of PRRSV[J].Archvirol Wien,1995,140(7),1313-131
[12]仇华吉,童光志,卢景良.猪生殖-呼吸道综合征病毒的分子生物学[J].国外兽医学-畜禽传染病,1997(3)：7-9
[13]Zimmerman J, Sanderson T, Eernisse K, et al. Transmission of SIRS virus inconvalescent animals to commingledpenmates under experimental conditions. Am Assoc Swine Pract New slett.1992,25
[14]Benfield D, Nelson JK, Rossow K, et al. Pathogenesis and persistenceof PRRS. In:Proceedings of the Allen D. Leman SwineConference.Vol.25.1998,169-171
[15]Allende R, Laegreid WW, Kutish GF, et al. Porcine reproductive and respiratory syndrome virus: description of persistence in individual pigs upon experimental infection.J Virol.2000,74:10834-10837
[16]刘光清,蔡雪辉,仇华吉,等.猪繁殖与呼吸道综合症的研究进展[J].中国预防兽医学报,2001,23：72-76
[17]Meulenberg JJ, LeGall A, Albina E, et al. Antigenic variability of Porcine Reproductive and Respiratory Syndrome (PRRS) Virus isolates. Influence of virus passage in pig.Vet Res,1997,28(3): 247-257
[18]FA Osorio, JA Galeota, E Nelson, B, et al. Passive transfer of virus-specific antibodies confers protection against reproductive failure induced by a virulent strain of porcine reproductive and respiratory syndrome virus and establishes sterilizing immunity. Virology,2002,302(1):9-20
[19]Ostrowski M, Galeota JA, Jar AM, et al. Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus.GP5.JVirol.2002,76(13):6863-72
[20]Rossow KD, Collins J S, Goyal S M. Vet. Patho,1995,32:361-373.
[21]Zimmennnan J, Yoon, KY, Pirtle. etal. Proc. Annu. Meet. Live. stock. Conserv Inst,1993, 107-108.
[22]Meng X J, Paul P S, Halbur P G, et al. Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV):implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe[J]. Arch Virol,1995,140(4):745-755.
[23]Suarez P, Zardoya R, Prieto C, et al. Detection of porcine reproductive and respiratory syndrome virus by reverse polymerase chain reaction (RT-PCR) [J].Arch Virol,1994,135:89-99
[24]Kono Y, et al. Neted PCR for detection and typing of porcine reproductive and respiratory syndrome virus in pigs [J].J Vet Med Sci 1996 Oct,58(10):941-946
[25]Legeay O, et al.Development of a RT-PCR test coupled with a microplate colorimetric assay for the detection of a swine Arterivirus(PRRSV) in boar semen [J]. J Virol methods 1997 Oct,68(1):65-80
[26]Sur JH, et al in vivo detection of porcine reproductive and respiratory syndrome virvus RNA by in situ hybridization atdifferent tirtms postinfection [J]. J Clin Microbial 19968ep,34{9):2280-2286
[27]Chen Ds, et al. Deteclion of nucleic acids of porcine reproduetive and respiratory syrArome virus Jr, the lungs of naturaHyinfected piglets as determined by Jr,-situ hybridizationf[J] J Comp Pathol 1997 Aug.117(2):157-163
[28]O. J. Lopez, M. F. Oliveira, E. Alvarez Garcia, et al. Protection against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection through Passive Transfer of PRRSV-Neutralizing Antibodies Is Dose Dependent.Clin. Vaccine Immunol.,2007,14:269-275.
[29]Plagemann PG, Rowland RR, Faaberg KS. The primary neutralization epitope of porcine respiratory and reproductive syndrome virus strain VR-2332 is located in the middle of the GP5 ectodomain. Arch Virol.2002,147(12) 2327-47
[30]KS Faaberg, JD Hocker, MM Erdman, et al. Neutralizing antibody responses of pigs infected with natural GP5 N-glycan mutants of porcine reproductive and respiratory syndrome virus. Viral Immunol,2006,19(2):294-304.
[31]Meullenbery J J, Peltrsen DEN, Eesten A D E, et al.Characterization of proteins encoded by ORFs 2to7 of Lelystad Virus.Virology.1997, (206):155-183
[32]Pirzadeh B, Dea S. Monoclonal antibodies to the ORF5 product of porcine reproductive and respiratory syndrome virus define linear neutralizing determinants. J Gen Virol.1997,78(8).1867-1873
[33]Gonin P, Pirzadeh B, Carl A. Sero neutralization of porcine reproductive and respiratory syndrome virus correlates with antibody response to the GP5 major envelope glycoprotein. J Vet Diagn Invest.1999,11:20-26
[34]Weiland E, Wieczorek-Krohmer M, et al. Monoclonal antibodies to the GP5 of porcine reproductive and respiratory syndrome virus are more effective in virus neutralization than monoclonal antibodies to the GP4. Vet Microbiol.1999,66(3)171-86
[35]Meulenberg JJ, Hulst MM, de Meijer EJ, et al. Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virology.1993, 192(1).62-72
[36]KwangJ, ZuckermannR, RossG Antibody and cellular immune responses of swine following immunization with plasmid DNA encoding the PRRS virus ORFs4,5,6 and7.Veterinary Science 1999, 67:199-201
[37]FA Osorio, JA Galeota, E Nelson, B, et al. Passive transfer of virus-specific antibodies confers protection against reproductive failure induced by a virulent strain of porcine reproductive and respiratory syndrome virus and establishes sterilizing immunity. Virology,2002,302(1):9-20
[38]JF Lowe, FA Zuckermann, LD Firkins, et al. Immunologic responses and reproductive outcomes following exposure to wild-type or attenuated porcine reproductive and respiratory syndrome virus in swine under field conditions. J Am Vet Med Assoc,2006,228(7):1082-8.
[39]Barfoed AM, Blixenkrone-Moller M, et al. DNA vaccination of pigs with open reading frame 1-7 of PRRS virus. Vaccine.2004,22(27-28) 3628-41
[40]Duran JP, Climent I, Sarraseca J, et al. Baculovirus expression of porcine reproductive and respiratory syndrome virus strain Olot/91.Involvement of ORF3 and ORF5 proteins in protection. Virus Genes.1997,.14:19-29
[411舒秀伟,宜华,王文成,等.猪繁殖与呼吸综合征病毒分子生物学研究进展[J].中国兽药杂志,2005,39(8)：36-40.
[42]王可洲,范韦兴.猪生殖-呼吸道综合征病毒的分子生物学研究现状[J].黑龙江畜牧兽医,2000,09：41-43
[43]周井祥.猪繁殖与呼吸综合征病毒GP5、M蛋白基因核酸疫苗和重组犬2型腺病毒疫苗构建及免疫原性的研究[D].吉林大学,2007
[44]宁宜宝,郑杰,张纯萍,等.我国南方猪高热病的研究(Ⅰ)[J].中国兽药杂志,2006,40(12)：1-4
[45]宁宜宝,郑杰,张纯萍,等.我国南方猪高热病的研究(Ⅱ)[J].中国兽药杂志,2007,41(1)：14-18
[46]KegongTian, XiulingYu, TiezhuZhao, et al. Emergence of Fatal PRRSV Variants:Unparalleled Outbreaks of Atypical PRRS in China and Molecular Dissection of the Unique Hallmark. http://www.pubmedcentral.nih.gov/articlerender.fcgi? artid=1885284
[47]郭宝清,陈章水,刘文兴,等.应用间接免疫荧光法从国内繁殖障碍综合征猪群中检测生殖和呼吸综合征阳性抗体的研究[J].中国兽医科技,1996,26(3)：3-5
[48]蔡宝祥.猪生殖-呼吸道综合症(PRRS)研究新进展[J].中国畜禽传染病,1998,20(增刊)：11-15
[49]Yoon KJ, Wu LL, Zimmerman JJ,etal. Field isolates of porcine reproductive and respiratory syndrome virus (PRRSV) vary in their susceptibility to antibody dependent enhancement(ADE) of infec-tion [J]. VetMircobio,l 1997,55(1-4):277-287
[50]WuWH, FangY, FarwellR,etal. A 10 ku structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b[J].Virology,2001287(1):183-191.
[51]Meulenberg JJ, HulstMM, DeMeijer EJ,et al. Lelystad virus,the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV[J]. Virology,1993,192(1): 62-72.
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[73]赵耕,罗长宝,林志雄等。猪繁殖与呼吸综合症病毒中国分离株B13株ORF5基因在杆状病毒系统中的表达[J].农业生物技术学报,2000,8(3)：211-215
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[2]Wensvoort G, de Kluyver EP, Pol JMA, et al. Lelystad virus, the cause of porcine epidemic abortionand respiratory syndrome:a review of mystery swine disease research at Lelystad. Vet Microbiol,1992
[3]Van Niienwstadt A.P., Meulenberg J.J.M., Van Essen-Zanbergen A., et al. Poteins encoded by open reading frames 3 and 4 of the genome of Lelystad virus (Arterviridae) are structural proteins of the virion J, Virol.70(1996):4767-4772
[4]Bautista E.M., Suarez P., Molitor W., et al. T cell responses to the structural polypeptides of porcinereproductive and respiratory syndrome virus, Arch.Virol.144(1999)117-134
[5]Wai-Hong.Wu, Yin Fang, Rachel Farwell, et al..A 10KU structure protein of PRRSV encoded by ORF2b. Virology 287,183-191(2001)
[6]Dea, s, Gagnon, C:A, Mardassi, H, Pirzadeh; B. and rogan, D.(2000)Current knowledge on the structural protein of prrsv; comparision of the north American and European isolates. arch virol 145659-688
[7]Conzelmann KK, Visser N, Van Woensel P, Thiel HJ(1993) Molecular charization of porcine reproductive and respiratory syndrome virus(PRRSV), a member of the arterirus group. Virology 193:329-339
[8]郭宝清,陈章水,刘文兴,等.从凝似PRRS流产胎儿分离PRRSV的研究[J].中国畜禽传染病.1996,(2)：1-4.
[9]Jusa ER, Inaba Y, Kouno M, et al Hemagglutination with porcine reproductive and respiratory syndrome virus[J]. J Vet Med Sci.1996,58:521-527
[10]陆承平.兽医微生物学(第四版)[M].北京：中国农业出版社,2007.443-445
[11]Morozov I, Meng X J, Paul P S.Sequence analysis of open readingframes(ORFs)2 to 4 of U.S.isolate of PRRSV[J].Archvirol Wien,1995,140(7),1313-131
[12]仇华吉,童光志,卢景良.猪生殖-呼吸道综合征病毒的分子生物学[J].国外兽医学-畜禽传染病,1997(3)：7-9
[13]Zimmerman J, Sanderson T, Eernisse K, et al. Transmission of SIRS virus inconvalescent animals to commingledpenmates under experimental conditions. Am Assoc Swine Pract New slett.1992,25
[14]Benfield D, Nelson JK, Rossow K, et al. Pathogenesis and persistenceof PRRS. In:Proceedings of the Allen D. Leman SwineConference.Vol.25.1998,169-171
[15]Allende R, Laegreid WW, Kutish GF, et al. Porcine reproductive and respiratory syndrome virus: description of persistence in individual pigs upon experimental infection.J Virol.2000,74:10834-10837
[16]刘光清,蔡雪辉,仇华吉,等.猪繁殖与呼吸道综合症的研究进展[J].中国预防兽医学报,2001,23：72-76
[17]Meulenberg JJ, LeGall A, Albina E, et al. Antigenic variability of Porcine Reproductive and Respiratory Syndrome (PRRS) Virus isolates. Influence of virus passage in pig.Vet Res,1997,28(3): 247-257
[18]FA Osorio, JA Galeota, E Nelson, B, et al. Passive transfer of virus-specific antibodies confers protection against reproductive failure induced by a virulent strain of porcine reproductive and respiratory syndrome virus and establishes sterilizing immunity. Virology,2002,302(1):9-20
[19]Ostrowski M, Galeota JA, Jar AM, et al. Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus.GP5.JVirol.2002,76(13):6863-72
[20]Rossow KD, Collins J S, Goyal S M. Vet. Patho,1995,32:361-373.
[21]Zimmennnan J, Yoon, KY, Pirtle. etal. Proc. Annu. Meet. Live. stock. Conserv Inst,1993, 107-108.
[22]Meng X J, Paul P S, Halbur P G, et al. Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV):implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe[J]. Arch Virol,1995,140(4):745-755.
[23]Suarez P, Zardoya R, Prieto C, et al. Detection of porcine reproductive and respiratory syndrome virus by reverse polymerase chain reaction (RT-PCR) [J].Arch Virol,1994,135:89-99
[24]Kono Y, et al. Neted PCR for detection and typing of porcine reproductive and respiratory syndrome virus in pigs [J].J Vet Med Sci 1996 Oct,58(10):941-946
[25]Legeay O, et al.Development of a RT-PCR test coupled with a microplate colorimetric assay for the detection of a swine Arterivirus(PRRSV) in boar semen [J]. J Virol methods 1997 Oct,68(1):65-80
[26]Sur JH, et al in vivo detection of porcine reproductive and respiratory syndrome virvus RNA by in situ hybridization atdifferent tirtms postinfection [J]. J Clin Microbial 19968ep,34{9):2280-2286
[27]Chen Ds, et al. Deteclion of nucleic acids of porcine reproduetive and respiratory syrArome virus Jr, the lungs of naturaHyinfected piglets as determined by Jr,-situ hybridizationf[J] J Comp Pathol 1997 Aug.117(2):157-163
[28]O. J. Lopez, M. F. Oliveira, E. Alvarez Garcia, et al. Protection against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection through Passive Transfer of PRRSV-Neutralizing Antibodies Is Dose Dependent.Clin. Vaccine Immunol.,2007,14:269-275.
[29]Plagemann PG, Rowland RR, Faaberg KS. The primary neutralization epitope of porcine respiratory and reproductive syndrome virus strain VR-2332 is located in the middle of the GP5 ectodomain. Arch Virol.2002,147(12) 2327-47
[30]KS Faaberg, JD Hocker, MM Erdman, et al. Neutralizing antibody responses of pigs infected with natural GP5 N-glycan mutants of porcine reproductive and respiratory syndrome virus. Viral Immunol,2006,19(2):294-304.
[31]Meullenbery J J, Peltrsen DEN, Eesten A D E, et al.Characterization of proteins encoded by ORFs 2to7 of Lelystad Virus.Virology.1997, (206):155-183
[32]Pirzadeh B, Dea S. Monoclonal antibodies to the ORF5 product of porcine reproductive and respiratory syndrome virus define linear neutralizing determinants. J Gen Virol.1997,78(8).1867-1873
[33]Gonin P, Pirzadeh B, Carl A. Sero neutralization of porcine reproductive and respiratory syndrome virus correlates with antibody response to the GP5 major envelope glycoprotein. J Vet Diagn Invest.1999,11:20-26
[34]Weiland E, Wieczorek-Krohmer M, et al. Monoclonal antibodies to the GP5 of porcine reproductive and respiratory syndrome virus are more effective in virus neutralization than monoclonal antibodies to the GP4. Vet Microbiol.1999,66(3)171-86
[35]Meulenberg JJ, Hulst MM, de Meijer EJ, et al. Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virology.1993, 192(1).62-72
[36]KwangJ, ZuckermannR, RossG Antibody and cellular immune responses of swine following immunization with plasmid DNA encoding the PRRS virus ORFs4,5,6 and7.Veterinary Science 1999, 67:199-201
[37]FA Osorio, JA Galeota, E Nelson, B, et al. Passive transfer of virus-specific antibodies confers protection against reproductive failure induced by a virulent strain of porcine reproductive and respiratory syndrome virus and establishes sterilizing immunity. Virology,2002,302(1):9-20
[38]JF Lowe, FA Zuckermann, LD Firkins, et al. Immunologic responses and reproductive outcomes following exposure to wild-type or attenuated porcine reproductive and respiratory syndrome virus in swine under field conditions. J Am Vet Med Assoc,2006,228(7):1082-8.
[39]Barfoed AM, Blixenkrone-Moller M, et al. DNA vaccination of pigs with open reading frame 1-7 of PRRS virus. Vaccine.2004,22(27-28) 3628-41
[40]Duran JP, Climent I, Sarraseca J, et al. Baculovirus expression of porcine reproductive and respiratory syndrome virus strain Olot/91.Involvement of ORF3 and ORF5 proteins in protection. Virus Genes.1997,.14:19-29
[411舒秀伟,宜华,王文成,等.猪繁殖与呼吸综合征病毒分子生物学研究进展[J].中国兽药杂志,2005,39(8)：36-40.
[42]王可洲,范韦兴.猪生殖-呼吸道综合征病毒的分子生物学研究现状[J].黑龙江畜牧兽医,2000,09：41-43
[43]周井祥.猪繁殖与呼吸综合征病毒GP5、M蛋白基因核酸疫苗和重组犬2型腺病毒疫苗构建及免疫原性的研究[D].吉林大学,2007
[44]宁宜宝,郑杰,张纯萍,等.我国南方猪高热病的研究(Ⅰ)[J].中国兽药杂志,2006,40(12)：1-4
[45]宁宜宝,郑杰,张纯萍,等.我国南方猪高热病的研究(Ⅱ)[J].中国兽药杂志,2007,41(1)：14-18
[46]KegongTian, XiulingYu, TiezhuZhao, et al. Emergence of Fatal PRRSV Variants:Unparalleled Outbreaks of Atypical PRRS in China and Molecular Dissection of the Unique Hallmark. http://www.pubmedcentral.nih.gov/articlerender.fcgi? artid=1885284
[47]郭宝清,陈章水,刘文兴,等.应用间接免疫荧光法从国内繁殖障碍综合征猪群中检测生殖和呼吸综合征阳性抗体的研究[J].中国兽医科技,1996,26(3)：3-5
[48]蔡宝祥.猪生殖-呼吸道综合症(PRRS)研究新进展[J].中国畜禽传染病,1998,20(增刊)：11-15
[49]Yoon KJ, Wu LL, Zimmerman JJ,etal. Field isolates of porcine reproductive and respiratory syndrome virus (PRRSV) vary in their susceptibility to antibody dependent enhancement(ADE) of infec-tion [J]. VetMircobio,l 1997,55(1-4):277-287
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