火针治疗带状疱疹急性期临床疗效及CD4和CD8观察
|
摘要
研究目的：
本课题将通过不同干预措施,观察火针与西药在治疗带状疱疹急性期的临床疗效及免疫指标CD4、CD8差异。从而验证火针在治疗带状疱疹急性期的临床疗效。为临床治疗带状疱疹提供一种有效、安全的治疗手段。
研究方法：
1.本研究采用前瞻性随机对照试验的研究方法,收集2011年1月至2012年4月广州市中医院针灸科住院部带状疱疹患者。
2.将符合纳入标准的受试者60例分为治疗组与对照组两组,其中火针治疗组30例,西药对照组30例。
3.治疗方法：
(1)火针治疗组：穴位选取病变皮损局部阿是穴、与皮损局部相对应的患侧夹脊穴(病变相应神经节段及上下各一节段)及双侧的支沟穴和后溪穴。
患者取卧位,在已选阿是穴上用艾尔碘消毒,点燃酒精灯,左手持酒精灯,右手持中粗火针在酒精灯的外焰加热针体,直至将针尖烧至红白后,迅速准确地刺入疱疹中央约0.2-0.3cm,根据疱疹数量的多少,先刺早发的疱疹,每次选择3-5个,每个疱疹针刺2次,术毕挤出疱液,按压约30秒钟,涂上一层万花油。
取患侧的夹脊穴,在穴位上涂上一层薄薄的万花油,用细火针浅刺约0.1cm。
取双侧的后溪穴及支沟穴,在穴位上涂上一层薄薄的万花油,用细火针浅刺约0.1cm。每日1次,10次为1个疗程,共计1个疗程。
(2)西药对照组：服用药物盐酸伐昔洛韦300mg/次,2次/日；维生素B1：口服：10mg,3次/日。
4.治疗结束后观察两组疱疹评分,疼痛评分,血清中免疫指标CD4、CD8水平变化,后遗神经痛的发生率及安全性评价等指标。
研究结果：
1.一般资料：共完成病例60例,分为治疗组30例,对照组30例,两组在年龄构成及性别构成均无统计学差异(P>0.05),两组具有可比性。
2.治疗效果：火针组治愈20例,好转10例,无效0例,有效率100%；西药组治愈7例,好转22例,无效1例,有效率96.7%。(P<0.05)说明火针疗效优于西药。
3.疱疹评分：在治疗措施干预前两组的疱疹评分无统计学差异(P>0.05),两组资料具有可比性。治疗组与对照组治疗后的疱疹评分进行比较(P<0.05)。说明火针在促进疱疹结痂、愈合、脱痂方面,火针疗效更优。
4.VAS评分：在治疗措施干预前两组的疼痛评分无统计学差异(P>0.05),两组具有可比性。火针组与西药组疼痛评分治疗后比较(P<0.05),有统计学意义。说明火针在减轻带状疱疹急性期疼痛方面优于西药。
5.CD4和CD8：治疗前两组的CD4、CD8及CD4/CD8水平差别无统计学差异(P>0.05),两组具有可比性。火针组与西药组治疗后CD4、CD8及CD4/CD8比较(P<0.05),有统计学意义。说明火针在改善免疫方面优于西药。
6.后遗神经痛的发生率：两组经过治疗后,后遗神经痛的发生率相比较,有统计学意义(P<0.05)。
结论：
火针在治疗带状疱疹急性期中,对于缩短疱疹的结痂时间,减轻急性期疼痛,减少后遗神经痛的发生上,较西药的疗效更为明显、确切、安全且副作用小。
Objective:
The task through different interventions methods to observe the differences between fire needle and western medicine in the treatment of herpes zoster acute phase of clinical efficacy and immune index of CD4, CD8. Verify the efficacy in the treatment of herpes zoster acute phase with the fire needle. Provide an effective and safe treatment for the clinical treatment of herpes zoster.
Methods:
The prospective randomized controlled study collected60patients from the Acupuncture Department of Guangzhou Hospital of Traditional Chinese Medicine during January2011to April2012. The patients were randomly divided into treatment group and comparison group. Which were divided into fire needle therapy group (30cases) and the comparison group (30cases). There are14cases of male,16cases of female. Aged18-69, the average age of the group is44.33years old. In the western medicine group, there are12cases of male,18cases of female. Aged18-70, average43.63years.
Methods of operation:1. Fire needle treatment group:(1)Acupuncture points selected lesions local ashi points, the local lesions corresponding to the ipsilateral Jiaji points (lesion corresponding nerve segment and up and down the one above) and Zhigou points (SJ6) and Houxi points (SI3).(2) Fire the needles in the outer flame heating above alcohol lamp. Then pick the fair needle into the center of the piercing herpes quickly and accurately about0.2-0.3cm. According to the number of the herpes, select3-5points of the early onset of herpes. And press out of the blister fluid about30seconds. Then pick the fire needles into Houxi Points and Zhigou points in this way. The treatment above should be arranged once a day,10times as a course of treatment.2. Western medicine:Famciclovir:300mg per time,2times per day and vitaminBl:10mg per time,3times per day. Observed the herpes score, the skin lesions subsided and the pain score, pain relief, time, pain relief, and serum immune parameters of CD4and CD8levels, the incidence of postherpetic neuralgia and safety evaluation of indicators after the treatment.
Results:
1. General information:Completed60ases divided into treatment group30cases and control group30cases. The two groups in age composition and sex were not statistically different (P>0.05), two groups were comparable.
2Effect after treatment:20cases were cured,10cases improved,0cases are invalid, the efficiency is100%. In western medicine group,7cases were cured,22cases improved,1cases are invalid, the efficiency is96.7%.(P<0.05) fire-needle therapy efficacy is superior to Western medicine.
3. Herpes score:Two groups before intervention measures in the treatment of herpes zoster scores showed no significant difference (P>0.05). The treatment group and the control group after treatment of herpes score for comparison (P<0.05). Description of acupuncture in promoting simplex crusted, healing, fire-needle therapy efficacy is superior to Western medicine.
4. VAS score:Two groups before intervention measures in the treatment of pain scores showed no significant difference (P>0.05), the two groups were comparable. Acupuncture group and Western medicine group pain score after treatment (P<0.05), with statistical significance. Description of fire-needle in alleviating acute herpes zoster is superior to Western medicine.
5. CD4and CD8before treatment in two groups:CD4, CD8and CD4/CD81evel difference is no statistical difference (P>0.05), the two groups were comparable. Fire needle group and Western medicine group after treatment with CD4, CD8and CD4/CD8(P<0.05), with statistical significance. Description of fire-needle in improving immune is superior to Western medicine.
6. The incidence of post herpetic neuralgia:two groups after treatment, the incidence of post herpetic neuralgia compared, statistically significant (P<0.05).
Conelusion:
Fire needle in the acute treatment of herpes zoster midterm shortening herpes scab time to alleviate the acute pain, reduce the incidence of post herpetic neuralgia, compared with the efficacy of western medicine is more obvious, the precise, safe and side effects.
本课题将通过不同干预措施,观察火针与西药在治疗带状疱疹急性期的临床疗效及免疫指标CD4、CD8差异。从而验证火针在治疗带状疱疹急性期的临床疗效。为临床治疗带状疱疹提供一种有效、安全的治疗手段。
研究方法：
1.本研究采用前瞻性随机对照试验的研究方法,收集2011年1月至2012年4月广州市中医院针灸科住院部带状疱疹患者。
2.将符合纳入标准的受试者60例分为治疗组与对照组两组,其中火针治疗组30例,西药对照组30例。
3.治疗方法：
(1)火针治疗组：穴位选取病变皮损局部阿是穴、与皮损局部相对应的患侧夹脊穴(病变相应神经节段及上下各一节段)及双侧的支沟穴和后溪穴。
患者取卧位,在已选阿是穴上用艾尔碘消毒,点燃酒精灯,左手持酒精灯,右手持中粗火针在酒精灯的外焰加热针体,直至将针尖烧至红白后,迅速准确地刺入疱疹中央约0.2-0.3cm,根据疱疹数量的多少,先刺早发的疱疹,每次选择3-5个,每个疱疹针刺2次,术毕挤出疱液,按压约30秒钟,涂上一层万花油。
取患侧的夹脊穴,在穴位上涂上一层薄薄的万花油,用细火针浅刺约0.1cm。
取双侧的后溪穴及支沟穴,在穴位上涂上一层薄薄的万花油,用细火针浅刺约0.1cm。每日1次,10次为1个疗程,共计1个疗程。
(2)西药对照组：服用药物盐酸伐昔洛韦300mg/次,2次/日；维生素B1：口服：10mg,3次/日。
4.治疗结束后观察两组疱疹评分,疼痛评分,血清中免疫指标CD4、CD8水平变化,后遗神经痛的发生率及安全性评价等指标。
研究结果：
1.一般资料：共完成病例60例,分为治疗组30例,对照组30例,两组在年龄构成及性别构成均无统计学差异(P>0.05),两组具有可比性。
2.治疗效果：火针组治愈20例,好转10例,无效0例,有效率100%；西药组治愈7例,好转22例,无效1例,有效率96.7%。(P<0.05)说明火针疗效优于西药。
3.疱疹评分：在治疗措施干预前两组的疱疹评分无统计学差异(P>0.05),两组资料具有可比性。治疗组与对照组治疗后的疱疹评分进行比较(P<0.05)。说明火针在促进疱疹结痂、愈合、脱痂方面,火针疗效更优。
4.VAS评分：在治疗措施干预前两组的疼痛评分无统计学差异(P>0.05),两组具有可比性。火针组与西药组疼痛评分治疗后比较(P<0.05),有统计学意义。说明火针在减轻带状疱疹急性期疼痛方面优于西药。
5.CD4和CD8：治疗前两组的CD4、CD8及CD4/CD8水平差别无统计学差异(P>0.05),两组具有可比性。火针组与西药组治疗后CD4、CD8及CD4/CD8比较(P<0.05),有统计学意义。说明火针在改善免疫方面优于西药。
6.后遗神经痛的发生率：两组经过治疗后,后遗神经痛的发生率相比较,有统计学意义(P<0.05)。
结论：
火针在治疗带状疱疹急性期中,对于缩短疱疹的结痂时间,减轻急性期疼痛,减少后遗神经痛的发生上,较西药的疗效更为明显、确切、安全且副作用小。
Objective:
The task through different interventions methods to observe the differences between fire needle and western medicine in the treatment of herpes zoster acute phase of clinical efficacy and immune index of CD4, CD8. Verify the efficacy in the treatment of herpes zoster acute phase with the fire needle. Provide an effective and safe treatment for the clinical treatment of herpes zoster.
Methods:
The prospective randomized controlled study collected60patients from the Acupuncture Department of Guangzhou Hospital of Traditional Chinese Medicine during January2011to April2012. The patients were randomly divided into treatment group and comparison group. Which were divided into fire needle therapy group (30cases) and the comparison group (30cases). There are14cases of male,16cases of female. Aged18-69, the average age of the group is44.33years old. In the western medicine group, there are12cases of male,18cases of female. Aged18-70, average43.63years.
Methods of operation:1. Fire needle treatment group:(1)Acupuncture points selected lesions local ashi points, the local lesions corresponding to the ipsilateral Jiaji points (lesion corresponding nerve segment and up and down the one above) and Zhigou points (SJ6) and Houxi points (SI3).(2) Fire the needles in the outer flame heating above alcohol lamp. Then pick the fair needle into the center of the piercing herpes quickly and accurately about0.2-0.3cm. According to the number of the herpes, select3-5points of the early onset of herpes. And press out of the blister fluid about30seconds. Then pick the fire needles into Houxi Points and Zhigou points in this way. The treatment above should be arranged once a day,10times as a course of treatment.2. Western medicine:Famciclovir:300mg per time,2times per day and vitaminBl:10mg per time,3times per day. Observed the herpes score, the skin lesions subsided and the pain score, pain relief, time, pain relief, and serum immune parameters of CD4and CD8levels, the incidence of postherpetic neuralgia and safety evaluation of indicators after the treatment.
Results:
1. General information:Completed60ases divided into treatment group30cases and control group30cases. The two groups in age composition and sex were not statistically different (P>0.05), two groups were comparable.
2Effect after treatment:20cases were cured,10cases improved,0cases are invalid, the efficiency is100%. In western medicine group,7cases were cured,22cases improved,1cases are invalid, the efficiency is96.7%.(P<0.05) fire-needle therapy efficacy is superior to Western medicine.
3. Herpes score:Two groups before intervention measures in the treatment of herpes zoster scores showed no significant difference (P>0.05). The treatment group and the control group after treatment of herpes score for comparison (P<0.05). Description of acupuncture in promoting simplex crusted, healing, fire-needle therapy efficacy is superior to Western medicine.
4. VAS score:Two groups before intervention measures in the treatment of pain scores showed no significant difference (P>0.05), the two groups were comparable. Acupuncture group and Western medicine group pain score after treatment (P<0.05), with statistical significance. Description of fire-needle in alleviating acute herpes zoster is superior to Western medicine.
5. CD4and CD8before treatment in two groups:CD4, CD8and CD4/CD81evel difference is no statistical difference (P>0.05), the two groups were comparable. Fire needle group and Western medicine group after treatment with CD4, CD8and CD4/CD8(P<0.05), with statistical significance. Description of fire-needle in improving immune is superior to Western medicine.
6. The incidence of post herpetic neuralgia:two groups after treatment, the incidence of post herpetic neuralgia compared, statistically significant (P<0.05).
Conelusion:
Fire needle in the acute treatment of herpes zoster midterm shortening herpes scab time to alleviate the acute pain, reduce the incidence of post herpetic neuralgia, compared with the efficacy of western medicine is more obvious, the precise, safe and side effects.
引文
[1]侯保民,陈晓醒.中西医结合治疗带状疱疹后遗神经痛疗效观察[J].使用中西医结合临床,2010,10(4)：56-57.
[2]廖桂华.带状疱疹的中医辨证施护及临床护理体会[J].中国民族民间医药,2010,6,195-196
[3]陈明.泛昔洛韦治疗带状疱疹的疗效观察[J].现代预防医学,2008：35,(21)4272-4273.
[4]骆津蓉.更昔洛韦治疗带状疱疹临床疗效观察[J].临床皮肤科杂志,2005：34,(8)：555.
[5]冯文利.单磷酸阿糖腺苷联合治疗泛昔洛韦治疗老年人带状疱疹51例疗效观察[J].中国中西医结合皮肤性病学杂志,2009,8(3)：179.
[6]王冬梅.阿昔洛韦联合干扰素治疗带状疱疹疗效观察[J].中国医学文摘,2009,26(2)：69-70.
[7]郭忆华.甲钴胺治疗三叉神经分布区带状疱疹20例[J].医学,2010,21(15)：36-38.
[8]曹建荣.常规四联方案治疗2056例带状疱疹的临床体会[J].社区卫生保健,2008,7(6)：437-439.
[9]刘礼锋.牛痘疫苗接种家兔炎症皮肤提取物注射液神经阻滞治疗带状疱疹后遗神经痛效果观察[J].中国乡村医药杂志,2009,16(2)：39—40.
[10]朱小娟,李彦希,郭霞.泛昔洛韦联合微波照射治疗带状疱疹疗效观察[J].重庆医学,2009,38(7)：858-871.
[11]林佳春,盛会,于勇.脊神经背根节身频靶点热凝术治疗带状疱疹后遗神经痛的临床观察[J].吉林医学,2009,30(3)：253.
[12]林惠英,王婧.紫外线配合超短波治疗带状疱疹46例疗效观察[J].广州医药,2009,40(2)：48—49.
[13]罗光浦.复方甘草酸苷片联合阿昔洛韦治疗中老年人带状疱疹[J].现代中西医结合杂志,2009,18(12)：1350.
[14]陈映琳,黄嵩,郭展华.阿昔洛韦软膏联合聚维酮碘软膏治疗带状疱疹皮损的疗效观察[J].河北医学,2009,15(3)：278-280.,
[15]周则琼,周书会,吴绍培.He—Ne激光联合阿昔洛韦治疗带状疱疹[J].中国激光医学杂志,2009,18(1)：60—61.
[16]刘海鹏。宋焱锋,王贤东.A型肉毒毒素治疗带状疱疹后遗神经痛临床研究[J].山东医药,2009,49(12)：71—72.
[17]刘毅斌,陈柳芳,盛正和.疏肝益肾化瘀方治疗老年带状疱疹后遗神经痛24例[J].陕西中医,2009,30(4)：438
[18]李文胜,高祥科.中药熏蒸配合疏皮疗法治疗带状疱疹后遗神经痛[J].临床合理用药,2009,2(3)：43-44.
[19]杜仕君.雄黄蒜泥外用治疗带状疱疹疗效观察[J].皮肤病与性病,2009,31(1)：34—35.
[20]路文梅,邵斌.铁锈白酒调涂治疗带状疱疹37例[J]. 中国民康医学,2009,21(6)：683.
[21]杨万金.中医综合疗法治疗带状疱疹56例[J].现代中医药,2009.29(2)：29—31.
[22]郭华.云南白药加食醋治疗带状疱疹.护理研究,2001,15(6)：312-312.
[23]王日云.甘草甜素治疗带状疱疹38例疗效观察[J].中国麻风皮肤病杂志,2001,17(3)：226-226.
[24]王岩红,王学吉,王海燕.板蓝根注射液治疗带状疱疹20例[J].新中医,2001,33(10)：55-56.
[25]王晓丽.综合疗法治疗带状疱疹28例[J].河南中医,2001,21(5)：52-52.
[26]何爱凤,刘秀华.聚肌胞联合六神丸治疗带状疱疹疗效观察[J].中医医刊,2002,29(2)：43-43.
[27]李义.桂林西瓜霜喷剂外敷治疗带状疱疹[J].中医药学报,2002,30(2)：34-34.
[28]陈红,陈新宇.清开灵注射液治疗带状疱疹62例[J].新中医,2002,34(6)：51-51.
[29]龚磊.藏药独一味治疗带状疱疹30例[J].临床皮肤科杂志,2001,30(2)：95-95.
[30]王广林,李明诚.双黄连粉针剂治疗带状疱疹58例[J].时珍国医国药,2003,14(5)：320-320.
[31]孙代红.蛇药片糊剂外用治疗眼部带状疱疹[J].时珍国医国药,2003,14(2)：93-93.
[32]许世芳.火针点刺治疗带状疱疹10例[J].新疆中医药,2008,26(2)：35.
[33]苏健淦。火针治疗带状疱疹急性期临床疗效观察[D]。广州中医药大学,2009年。
[34]罗岚。火针为主治疗急性期带状疱疹疗效观察[D]。广州中医药大学,2009年。
[35]黄雪梅,薛爱国,李秀霞,等。火针配合针刺治疗急性期带状疱疹40例疗效观察[J]。湖南中医药导报,2003,9(8)：36-37。
[36]钟辉.火针加火罐治疗带状疱疹34例报告[J].甘肃中医,2001,14(4)：62—63
[37]梁吉,刘泓.火针配合拔罐治疗带状疱疹36例[J].中国针灸,1999,(9)t538
[38]刘芳.火针治疗带状疱疹55例[J].内蒙古中医药,2007,26(1)：21
[39]马新平,蒋微微.火针拔罐并用治疗带状疱疹后遗神经痛50例[J].实用中医内科杂志,2005,19(5)：482.
[40]孙永进.火针配合拔罐治疗带状疱疹后遗神经痛130例[J].中医外科杂志,2006,15(4)：21.
[41]安凤华.火针配拔罐治疗带状疱疹神经痛56例[J].中国临床医药研究杂志,2003,106：60.
[42]徐华章.火针结合艾条治疗带状疱疹45例[J].实用中医药杂志,2003,19(9)：487
[43]吕敏捷,罗振江.火针配合艾灸治疗急性期带状疱疹58例[J].河北中医,2007,27(8)：65.
[44]岳进,莫智珍.多头火针治疗带状疱疹35例[J].福建中医药,2008,39(1)：32.
[45]黄时燕,吴祖兰,唐盛容.火针加灸法配合西药治疗带状疱疹疗效观察[J].北京中医,2006,25(4)：243—244
[46]聂发华.火针、拔罐配合TDP照射治疗带状疱疹35例[J].新疆中医药,2003,21(3)：24.
[47]王卫红.火针点刺、针灸加罐法治疗带状疱疹369例[J].中国临床医生,2004,32(6)：58.
[48]王希光.用火针综合治疗带状疱疹37例小结[J].湖南中医药导报,2002,8(10)：600.
[49]谢晋,盛骥锋.火针加罐及外涂药物综合治疗带状疱疹60例临床观察[J].中医外科杂志,2004,13(3)：25.
[50]刘红宇.火针配合六黄散外敷治疗带状疱疹[J].中医外治杂志,1999,8(5)：36
[51]王希光.用火针综合治疗带状疱疹37例小结[J].湖南中医药导报,2002,8(10)：600
[52]钱月萍.芦荟汁外擦配合火针治疗带状疱疹25例[J].海峡药学,2005,17(5)：153—154
[53]聂斌,蔡少华.火针半刺法治疗带状疱疹临床疗效评价[J].江西中医学院学报,2006,18(3)：38—39
[54]王希光.用火针综合治疗带状疱疹37例小结[J].湖南中医药导报,2002,8(10)：600
[55]朱玉景,王秀军.激光针、火针加拔罐治疗带状疱疹196例[J].上海针灸杂志,2004,23(6)：
[2]廖桂华.带状疱疹的中医辨证施护及临床护理体会[J].中国民族民间医药,2010,6,195-196
[3]陈明.泛昔洛韦治疗带状疱疹的疗效观察[J].现代预防医学,2008：35,(21)4272-4273.
[4]骆津蓉.更昔洛韦治疗带状疱疹临床疗效观察[J].临床皮肤科杂志,2005：34,(8)：555.
[5]冯文利.单磷酸阿糖腺苷联合治疗泛昔洛韦治疗老年人带状疱疹51例疗效观察[J].中国中西医结合皮肤性病学杂志,2009,8(3)：179.
[6]王冬梅.阿昔洛韦联合干扰素治疗带状疱疹疗效观察[J].中国医学文摘,2009,26(2)：69-70.
[7]郭忆华.甲钴胺治疗三叉神经分布区带状疱疹20例[J].医学,2010,21(15)：36-38.
[8]曹建荣.常规四联方案治疗2056例带状疱疹的临床体会[J].社区卫生保健,2008,7(6)：437-439.
[9]刘礼锋.牛痘疫苗接种家兔炎症皮肤提取物注射液神经阻滞治疗带状疱疹后遗神经痛效果观察[J].中国乡村医药杂志,2009,16(2)：39—40.
[10]朱小娟,李彦希,郭霞.泛昔洛韦联合微波照射治疗带状疱疹疗效观察[J].重庆医学,2009,38(7)：858-871.
[11]林佳春,盛会,于勇.脊神经背根节身频靶点热凝术治疗带状疱疹后遗神经痛的临床观察[J].吉林医学,2009,30(3)：253.
[12]林惠英,王婧.紫外线配合超短波治疗带状疱疹46例疗效观察[J].广州医药,2009,40(2)：48—49.
[13]罗光浦.复方甘草酸苷片联合阿昔洛韦治疗中老年人带状疱疹[J].现代中西医结合杂志,2009,18(12)：1350.
[14]陈映琳,黄嵩,郭展华.阿昔洛韦软膏联合聚维酮碘软膏治疗带状疱疹皮损的疗效观察[J].河北医学,2009,15(3)：278-280.,
[15]周则琼,周书会,吴绍培.He—Ne激光联合阿昔洛韦治疗带状疱疹[J].中国激光医学杂志,2009,18(1)：60—61.
[16]刘海鹏。宋焱锋,王贤东.A型肉毒毒素治疗带状疱疹后遗神经痛临床研究[J].山东医药,2009,49(12)：71—72.
[17]刘毅斌,陈柳芳,盛正和.疏肝益肾化瘀方治疗老年带状疱疹后遗神经痛24例[J].陕西中医,2009,30(4)：438
[18]李文胜,高祥科.中药熏蒸配合疏皮疗法治疗带状疱疹后遗神经痛[J].临床合理用药,2009,2(3)：43-44.
[19]杜仕君.雄黄蒜泥外用治疗带状疱疹疗效观察[J].皮肤病与性病,2009,31(1)：34—35.
[20]路文梅,邵斌.铁锈白酒调涂治疗带状疱疹37例[J]. 中国民康医学,2009,21(6)：683.
[21]杨万金.中医综合疗法治疗带状疱疹56例[J].现代中医药,2009.29(2)：29—31.
[22]郭华.云南白药加食醋治疗带状疱疹.护理研究,2001,15(6)：312-312.
[23]王日云.甘草甜素治疗带状疱疹38例疗效观察[J].中国麻风皮肤病杂志,2001,17(3)：226-226.
[24]王岩红,王学吉,王海燕.板蓝根注射液治疗带状疱疹20例[J].新中医,2001,33(10)：55-56.
[25]王晓丽.综合疗法治疗带状疱疹28例[J].河南中医,2001,21(5)：52-52.
[26]何爱凤,刘秀华.聚肌胞联合六神丸治疗带状疱疹疗效观察[J].中医医刊,2002,29(2)：43-43.
[27]李义.桂林西瓜霜喷剂外敷治疗带状疱疹[J].中医药学报,2002,30(2)：34-34.
[28]陈红,陈新宇.清开灵注射液治疗带状疱疹62例[J].新中医,2002,34(6)：51-51.
[29]龚磊.藏药独一味治疗带状疱疹30例[J].临床皮肤科杂志,2001,30(2)：95-95.
[30]王广林,李明诚.双黄连粉针剂治疗带状疱疹58例[J].时珍国医国药,2003,14(5)：320-320.
[31]孙代红.蛇药片糊剂外用治疗眼部带状疱疹[J].时珍国医国药,2003,14(2)：93-93.
[32]许世芳.火针点刺治疗带状疱疹10例[J].新疆中医药,2008,26(2)：35.
[33]苏健淦。火针治疗带状疱疹急性期临床疗效观察[D]。广州中医药大学,2009年。
[34]罗岚。火针为主治疗急性期带状疱疹疗效观察[D]。广州中医药大学,2009年。
[35]黄雪梅,薛爱国,李秀霞,等。火针配合针刺治疗急性期带状疱疹40例疗效观察[J]。湖南中医药导报,2003,9(8)：36-37。
[36]钟辉.火针加火罐治疗带状疱疹34例报告[J].甘肃中医,2001,14(4)：62—63
[37]梁吉,刘泓.火针配合拔罐治疗带状疱疹36例[J].中国针灸,1999,(9)t538
[38]刘芳.火针治疗带状疱疹55例[J].内蒙古中医药,2007,26(1)：21
[39]马新平,蒋微微.火针拔罐并用治疗带状疱疹后遗神经痛50例[J].实用中医内科杂志,2005,19(5)：482.
[40]孙永进.火针配合拔罐治疗带状疱疹后遗神经痛130例[J].中医外科杂志,2006,15(4)：21.
[41]安凤华.火针配拔罐治疗带状疱疹神经痛56例[J].中国临床医药研究杂志,2003,106：60.
[42]徐华章.火针结合艾条治疗带状疱疹45例[J].实用中医药杂志,2003,19(9)：487
[43]吕敏捷,罗振江.火针配合艾灸治疗急性期带状疱疹58例[J].河北中医,2007,27(8)：65.
[44]岳进,莫智珍.多头火针治疗带状疱疹35例[J].福建中医药,2008,39(1)：32.
[45]黄时燕,吴祖兰,唐盛容.火针加灸法配合西药治疗带状疱疹疗效观察[J].北京中医,2006,25(4)：243—244
[46]聂发华.火针、拔罐配合TDP照射治疗带状疱疹35例[J].新疆中医药,2003,21(3)：24.
[47]王卫红.火针点刺、针灸加罐法治疗带状疱疹369例[J].中国临床医生,2004,32(6)：58.
[48]王希光.用火针综合治疗带状疱疹37例小结[J].湖南中医药导报,2002,8(10)：600.
[49]谢晋,盛骥锋.火针加罐及外涂药物综合治疗带状疱疹60例临床观察[J].中医外科杂志,2004,13(3)：25.
[50]刘红宇.火针配合六黄散外敷治疗带状疱疹[J].中医外治杂志,1999,8(5)：36
[51]王希光.用火针综合治疗带状疱疹37例小结[J].湖南中医药导报,2002,8(10)：600
[52]钱月萍.芦荟汁外擦配合火针治疗带状疱疹25例[J].海峡药学,2005,17(5)：153—154
[53]聂斌,蔡少华.火针半刺法治疗带状疱疹临床疗效评价[J].江西中医学院学报,2006,18(3)：38—39
[54]王希光.用火针综合治疗带状疱疹37例小结[J].湖南中医药导报,2002,8(10)：600
[55]朱玉景,王秀军.激光针、火针加拔罐治疗带状疱疹196例[J].上海针灸杂志,2004,23(6)：