一效膏在混合痔外剥内扎术后应用的临床研究
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摘要
目的:观察一效膏在混合痔外剥内扎术后切口换药中减轻局部疼痛、水肿,促进切口愈合的作用。
方法:根据随机、对照的科研设计原则,采用随机法将符合试验标准的103个患者随机分为治疗组52例和对照组51例。对52例混合痔外剥内扎术后患者(治疗组)给予由辽宁中医药大学附属医院制剂室提供的一效膏换药,并与51例采用马应龙麝香痔疮膏(武汉马应龙药业集团股份有限公司生产)换药的混合痔外剥内扎术后患者(对照组)进行疗效对比,以科学的评价其临床疗效。
结果:通过临床观察,治疗组与对照组相比,其术后疼痛程度、水肿程度均有显著性差异(p<0.05),治疗组优于对照组;两组在创面愈合时间上有极其显著差异(p<0.01),治疗组明显优于对照组。
结论:一效膏具有良好的消炎、消肿止痛、收敛生肌效果。混合痔外剥内扎术后患者采用一效膏换药,取得了较好的临床效果,既减少了患者术后肛门疼痛、水肿等并发症的发生,又减少了切口愈合时间。此方法安全有效,使用方便,价格低廉,值得临床推广应用。
Purpose: To observe the effects of YiXiao Ointment (YXO) dressing change on reducing the local pain, edema , and promoting wound healing of patients after operation of mixed hemorrhoids with Milligan-Morgan Hemorrhoidectomy.
Methods: The study population consisted of 103 patients after operation of mixed hemorrhoids with Milligan-Morgan Hemorrhoidectomy.The treatment group with 52 cases and the contrast group with 51 cases were randomly collected and treated by YXO and Mayinglong Shexiang zhichuang Ointment (MSO) respectively, and the therapeutic effects were compared.
Results:In comparison with the contrast group, the degree of postoperative pain and edema in the treatment group were all significantly reduced (p<0.05), meanwhile the wound healing time of the treatment group was shorter distinctively (p<0.01).
Conclusion:YXO has the effect of activating blood circulation to dissipate blood stasis detumescence and promoting granulation. Patients after operation of mixed hemorrhoids with Milligan-Morgan Hemorrhoidectomy combined with YXO dressing change can achieve better clinical results by reducing postoperative complications,such as postoperative pain and edema. This is a simple, safe, effective and cheap method and worth to spread.
方法:根据随机、对照的科研设计原则,采用随机法将符合试验标准的103个患者随机分为治疗组52例和对照组51例。对52例混合痔外剥内扎术后患者(治疗组)给予由辽宁中医药大学附属医院制剂室提供的一效膏换药,并与51例采用马应龙麝香痔疮膏(武汉马应龙药业集团股份有限公司生产)换药的混合痔外剥内扎术后患者(对照组)进行疗效对比,以科学的评价其临床疗效。
结果:通过临床观察,治疗组与对照组相比,其术后疼痛程度、水肿程度均有显著性差异(p<0.05),治疗组优于对照组;两组在创面愈合时间上有极其显著差异(p<0.01),治疗组明显优于对照组。
结论:一效膏具有良好的消炎、消肿止痛、收敛生肌效果。混合痔外剥内扎术后患者采用一效膏换药,取得了较好的临床效果,既减少了患者术后肛门疼痛、水肿等并发症的发生,又减少了切口愈合时间。此方法安全有效,使用方便,价格低廉,值得临床推广应用。
Purpose: To observe the effects of YiXiao Ointment (YXO) dressing change on reducing the local pain, edema , and promoting wound healing of patients after operation of mixed hemorrhoids with Milligan-Morgan Hemorrhoidectomy.
Methods: The study population consisted of 103 patients after operation of mixed hemorrhoids with Milligan-Morgan Hemorrhoidectomy.The treatment group with 52 cases and the contrast group with 51 cases were randomly collected and treated by YXO and Mayinglong Shexiang zhichuang Ointment (MSO) respectively, and the therapeutic effects were compared.
Results:In comparison with the contrast group, the degree of postoperative pain and edema in the treatment group were all significantly reduced (p<0.05), meanwhile the wound healing time of the treatment group was shorter distinctively (p<0.01).
Conclusion:YXO has the effect of activating blood circulation to dissipate blood stasis detumescence and promoting granulation. Patients after operation of mixed hemorrhoids with Milligan-Morgan Hemorrhoidectomy combined with YXO dressing change can achieve better clinical results by reducing postoperative complications,such as postoperative pain and edema. This is a simple, safe, effective and cheap method and worth to spread.
引文
[1]赵宝明,张书信,芮洪顺.实用肛门直肠病治疗学[M],北京:人民军医出版社,2009.8:54.
[2]杨关根,杨琴燕,左振魁等.改良Milligan一Morgan术治疗环状痔[J].中华胃肠外科杂志,2006,9(5):420.
[3]黎海龙,熊婕,苗青.地奥司明片治疗痔外剥内扎术后水肿的疗效观察[J].世界中西医结合杂志,2009,4(2):122.
[4]汤东澄,叶升福.草木犀流浸液片剂治疗痔疮临床疗效观察[J].安徽医药,2008,12(8):741.
[5]杨新庆.复方银杏叶萃取物胶囊用于痔术后的临床研究[J].大肠肛门病外科杂志,2004,10(1):44-46.
[6]孙敏,吴文英.爱脉朗治疗产后痔疮急性发作41例[J].中国药业临床医药,2010,19(15):33.
[7]傅新民.强力脉痔灵治疗痔疮260例疗效观察[J].大肠肛门病外科杂志,1998,4(3):144.
[8]蒋娟,赵树琴.中药熏洗对痔术后切口疼痛的影响[J].实用临床医药杂志:护理版,2006,2(5):90-91.
[9]何颖华,寇玉明,赖旖.复方四黄膏治疗混合痔术后疼痛及水肿30例[J].陕西中医,2009,30(11):1491.
[10]黄永兵,蔡兰兰,陈国文.九华痔疮栓治疗内痔60例临床观察[J].中国实用医药,2009,4(33):112-113.
[11]黄乃健.中国肛肠病学[M],山东:山东科学技术出版社,1996.6:653
[12]鲁兵,刘玉祥,周坤.保留齿状线分段外切内注术治疗结缔组织型环状混合痔疗效观察[J].大肠肛门病外科杂志,2005,11(1):38-40.
[13]陆金根,丁义江,李国栋.中西医结合肛肠病学[M],北京:中国中医药出版社,2009.6:162.
[14]李东平,首汉蓉.痔的概念与外科治疗[J].结直肠肛门外科,2007.13(5):87
[15]傅传刚,姚航.痔的外科治疗进展[J].中国现代手术学杂志,2003.6,7(3):168.
[16]李世岳.混合痔术后水肿分析与治疗[J].浙江中西医结合杂志,2002,,12(2):91.
[17]宋铎,李娜,何鑫.马应龙麝香痔疮膏加微波治疗重度痔疮[J].辽宁中医杂志,2004. 11,31(11):935.
[18]杨新庆.红外凝结器治疗内痔[J].中国肛肠病杂志,1991;11(3):3.
[19]李宏学,顾志强.CO2激光治疗痔疮5000例体会[J].应用激光,1996,16(5):240. [20]吕孝东,田志刚.电子痔疮仪与注射消痔灵治疗内痔疗效比较[J].苏州中医药学报,1998,18(8):848.
[21]傅传刚.痔术式的演变[J].中国实用外科杂志,2001,21(11):686—687.
[22]丁闯,胡浩,曹苇等.吻合器痔上黏膜环切术治疗痔109例分析[J].中国误诊学杂志,2010,10(4)902-903.
[23]肖立新,陆金根.外剥内扎悬吊术治疗环状混合痔的临床观察[J].中西医结合学报,2007;5(4):460-462.
[24]臧传波,罗成华,李荣等.应用结扎速血管闭合系统行痔切除19例临床观察[J].中国实用外科杂志,2006,26(12b):968.
[25]钟智佳,曾轶晖.多普勒超声引导痔动脉结扎治疗痔的临床疗效观察[J].中国医药指南,2010,2(5)8-10.
[26]陆金根,丁义江,李国栋.中西医结合肛肠病学[M],北京:中国中医药出版社,2009.6:157.
[27]赵宝明,张书信,芮洪顺.实用肛门直肠病治疗学[M],北京:人民军医出版社,2009.8:76.
[28]林巧梅,高峰,黄如华.中西医结合治疗痔术后水肿50例[J].福建中医药,2005,36,(2):56.
[29]葛德贵.保留齿线新术式治疗混合痔[J].临床外科杂志,2003;1l(增刊):90-91.
[30]孙燕,罗爱伦.麻醉药品临床使用与规范化管理培训教材[M].北京:卫生部医政司,2005:8-9.
[31]高枫.肛垫的研究进展对痔治疗的影响[J].中国现代手术学杂志,2008,7(3):164.
[32]喻德洪,杨新庆,黄筵庭.重新认识提高痔的诊治水平[J].中华外科杂志,2000,38(12):890-891.
[33]臧传波,罗成华,李荣等.中国实用外科杂志2006,26(12b):968.
[2]杨关根,杨琴燕,左振魁等.改良Milligan一Morgan术治疗环状痔[J].中华胃肠外科杂志,2006,9(5):420.
[3]黎海龙,熊婕,苗青.地奥司明片治疗痔外剥内扎术后水肿的疗效观察[J].世界中西医结合杂志,2009,4(2):122.
[4]汤东澄,叶升福.草木犀流浸液片剂治疗痔疮临床疗效观察[J].安徽医药,2008,12(8):741.
[5]杨新庆.复方银杏叶萃取物胶囊用于痔术后的临床研究[J].大肠肛门病外科杂志,2004,10(1):44-46.
[6]孙敏,吴文英.爱脉朗治疗产后痔疮急性发作41例[J].中国药业临床医药,2010,19(15):33.
[7]傅新民.强力脉痔灵治疗痔疮260例疗效观察[J].大肠肛门病外科杂志,1998,4(3):144.
[8]蒋娟,赵树琴.中药熏洗对痔术后切口疼痛的影响[J].实用临床医药杂志:护理版,2006,2(5):90-91.
[9]何颖华,寇玉明,赖旖.复方四黄膏治疗混合痔术后疼痛及水肿30例[J].陕西中医,2009,30(11):1491.
[10]黄永兵,蔡兰兰,陈国文.九华痔疮栓治疗内痔60例临床观察[J].中国实用医药,2009,4(33):112-113.
[11]黄乃健.中国肛肠病学[M],山东:山东科学技术出版社,1996.6:653
[12]鲁兵,刘玉祥,周坤.保留齿状线分段外切内注术治疗结缔组织型环状混合痔疗效观察[J].大肠肛门病外科杂志,2005,11(1):38-40.
[13]陆金根,丁义江,李国栋.中西医结合肛肠病学[M],北京:中国中医药出版社,2009.6:162.
[14]李东平,首汉蓉.痔的概念与外科治疗[J].结直肠肛门外科,2007.13(5):87
[15]傅传刚,姚航.痔的外科治疗进展[J].中国现代手术学杂志,2003.6,7(3):168.
[16]李世岳.混合痔术后水肿分析与治疗[J].浙江中西医结合杂志,2002,,12(2):91.
[17]宋铎,李娜,何鑫.马应龙麝香痔疮膏加微波治疗重度痔疮[J].辽宁中医杂志,2004. 11,31(11):935.
[18]杨新庆.红外凝结器治疗内痔[J].中国肛肠病杂志,1991;11(3):3.
[19]李宏学,顾志强.CO2激光治疗痔疮5000例体会[J].应用激光,1996,16(5):240. [20]吕孝东,田志刚.电子痔疮仪与注射消痔灵治疗内痔疗效比较[J].苏州中医药学报,1998,18(8):848.
[21]傅传刚.痔术式的演变[J].中国实用外科杂志,2001,21(11):686—687.
[22]丁闯,胡浩,曹苇等.吻合器痔上黏膜环切术治疗痔109例分析[J].中国误诊学杂志,2010,10(4)902-903.
[23]肖立新,陆金根.外剥内扎悬吊术治疗环状混合痔的临床观察[J].中西医结合学报,2007;5(4):460-462.
[24]臧传波,罗成华,李荣等.应用结扎速血管闭合系统行痔切除19例临床观察[J].中国实用外科杂志,2006,26(12b):968.
[25]钟智佳,曾轶晖.多普勒超声引导痔动脉结扎治疗痔的临床疗效观察[J].中国医药指南,2010,2(5)8-10.
[26]陆金根,丁义江,李国栋.中西医结合肛肠病学[M],北京:中国中医药出版社,2009.6:157.
[27]赵宝明,张书信,芮洪顺.实用肛门直肠病治疗学[M],北京:人民军医出版社,2009.8:76.
[28]林巧梅,高峰,黄如华.中西医结合治疗痔术后水肿50例[J].福建中医药,2005,36,(2):56.
[29]葛德贵.保留齿线新术式治疗混合痔[J].临床外科杂志,2003;1l(增刊):90-91.
[30]孙燕,罗爱伦.麻醉药品临床使用与规范化管理培训教材[M].北京:卫生部医政司,2005:8-9.
[31]高枫.肛垫的研究进展对痔治疗的影响[J].中国现代手术学杂志,2008,7(3):164.
[32]喻德洪,杨新庆,黄筵庭.重新认识提高痔的诊治水平[J].中华外科杂志,2000,38(12):890-891.
[33]臧传波,罗成华,李荣等.中国实用外科杂志2006,26(12b):968.