海水浸泡开放性犬颅脑爆震伤影像学变化及机制实验研究
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摘要
目的:研究海战条件下开放性颅脑爆震伤动物模型颅脑影像学的变化特点。
方法:以狗颅中线向左(右)1cm,眶上缘向上1cm交界处为爆炸中心位置。将15只犬根据爆炸距离(爆炸源最低点距爆炸点的距离)分为3组,分别为3mm组、3.5mm组、4mm组。比较各个组的爆炸效果,选出最适的爆炸距离为3.5mm。再将20只犬随机分为对照组(非海水浸泡),实验组(海水浸泡)。以爆炸距离3.5mm致伤后,实验组犬受伤脑组织浸泡于海水环境中,比较两组犬致伤3h、5h、8h后颅脑CT的动态变化。
结果:经颅脑动态CT观察,实验组犬8小时内脑水肿出现时间晚于对照组,同时脑水肿程度明显轻于对照组。
结论:海水浸泡在8小时内可以明显延缓脑水肿出现。
Objective: To study the dynamic Imaging changes of dogs under conditions of open craniocerebral explosive injury immersed in Seawater.
Methods: the explosive site is the junction between the midline of dogs’head left (right) to 1cm and supraorbital margin up to 1cm. We divided dogs into 3 groups in accordance with the explosive distance (The minimum distance from the lowest point of the explosion ball to the explosive site).The 3 groups are 3mm group, 3.5mm group, 4mm group respectively. We compared explosive results of three groups, and selected the most appropriate explosive distance. The appropriate explosive distance is 3.5mm. 20 dogs were randomly divided into the control group (non-seawater immersion) and the experimental group (seawater immersion). After injury (The appropriate explosive distance is 3.5mm), we soaked dogs’head of the experimental group in seawater environment, and compared the dynamic CT changes of two groups’dogs injured 3h, 5h, 8h.
Results: By dynamic CT observation, the time of the experimental group dogs with cerebral edema is later than the time of the control group during 8 hours. The degree of cerebral edema in the control group at the same time is more serious than the experimental group significantly.
Conclusion: 8 hours soaking in seawater can significantly delay the emergence of cerebral edema.
方法:以狗颅中线向左(右)1cm,眶上缘向上1cm交界处为爆炸中心位置。将15只犬根据爆炸距离(爆炸源最低点距爆炸点的距离)分为3组,分别为3mm组、3.5mm组、4mm组。比较各个组的爆炸效果,选出最适的爆炸距离为3.5mm。再将20只犬随机分为对照组(非海水浸泡),实验组(海水浸泡)。以爆炸距离3.5mm致伤后,实验组犬受伤脑组织浸泡于海水环境中,比较两组犬致伤3h、5h、8h后颅脑CT的动态变化。
结果:经颅脑动态CT观察,实验组犬8小时内脑水肿出现时间晚于对照组,同时脑水肿程度明显轻于对照组。
结论:海水浸泡在8小时内可以明显延缓脑水肿出现。
Objective: To study the dynamic Imaging changes of dogs under conditions of open craniocerebral explosive injury immersed in Seawater.
Methods: the explosive site is the junction between the midline of dogs’head left (right) to 1cm and supraorbital margin up to 1cm. We divided dogs into 3 groups in accordance with the explosive distance (The minimum distance from the lowest point of the explosion ball to the explosive site).The 3 groups are 3mm group, 3.5mm group, 4mm group respectively. We compared explosive results of three groups, and selected the most appropriate explosive distance. The appropriate explosive distance is 3.5mm. 20 dogs were randomly divided into the control group (non-seawater immersion) and the experimental group (seawater immersion). After injury (The appropriate explosive distance is 3.5mm), we soaked dogs’head of the experimental group in seawater environment, and compared the dynamic CT changes of two groups’dogs injured 3h, 5h, 8h.
Results: By dynamic CT observation, the time of the experimental group dogs with cerebral edema is later than the time of the control group during 8 hours. The degree of cerebral edema in the control group at the same time is more serious than the experimental group significantly.
Conclusion: 8 hours soaking in seawater can significantly delay the emergence of cerebral edema.
引文
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