康脉Ⅱ号胶囊治疗下肢深静脉血栓形成的临床研究
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摘要
目的:观察康脉Ⅱ号胶囊治疗下肢深静脉血栓形成的临床疗效。
方法:选择60例下肢深静脉血栓形成的患者,随机分为2组,治疗组30例,口服康脉Ⅱ号胶囊(由黑龙江中医药大学附属一院药厂生产,其主要成分为蓬子菜、茯苓、黄柏、三棱、莪术、苍术、甘草),一次5粒,一日三次,每粒含生药5克。对照组30例,口服通塞脉片(江苏南星药业有限责任公司生产,48片/盒),一次5片,一日三次。对治疗前后症状、体征,血液流变学,内皮素-1,6-酮-前列腺素F_1α等指标检测。
结果:治疗组30例,总有效率93.33%,对照组30例,总有效率73.33%,6-酮-前列腺素F_1α、内皮素-1,血液流变指标均有不同程度降低,治疗前后症状,体征均有改善,经统计学分析,两组疗效比较有显著性差异。
结论:康脉Ⅱ号胶囊对下肢深静脉血栓形成有良好的治疗作用,且疗效优于通塞脉片。
Objective:To observe and appraise its clinical curative effect synthetically on LDVT treated by Kang MaiⅡcapsule.
Methods:we selected 30 patients treated by Kang MaiⅡcapsule as therapeutic group and other 30 patients treated by Tongsaimai tablet as control group.The symptoms and physical sign,the remark of hemanalysis and ET-1,6-K-PGF_1αwere detacted before treatment group.
Results:The therapeutic group total effective rate was 93.33%,while the control group total effective rate was 73.33%,with statistics analysis, the different between the two groups was significant.
Conlusion:We can draw a conclusion that Kang MaiⅡcapsule plays a positive role in the treatment of LDVT,and there is more effctive than Tongsaimai tablet.
方法:选择60例下肢深静脉血栓形成的患者,随机分为2组,治疗组30例,口服康脉Ⅱ号胶囊(由黑龙江中医药大学附属一院药厂生产,其主要成分为蓬子菜、茯苓、黄柏、三棱、莪术、苍术、甘草),一次5粒,一日三次,每粒含生药5克。对照组30例,口服通塞脉片(江苏南星药业有限责任公司生产,48片/盒),一次5片,一日三次。对治疗前后症状、体征,血液流变学,内皮素-1,6-酮-前列腺素F_1α等指标检测。
结果:治疗组30例,总有效率93.33%,对照组30例,总有效率73.33%,6-酮-前列腺素F_1α、内皮素-1,血液流变指标均有不同程度降低,治疗前后症状,体征均有改善,经统计学分析,两组疗效比较有显著性差异。
结论:康脉Ⅱ号胶囊对下肢深静脉血栓形成有良好的治疗作用,且疗效优于通塞脉片。
Objective:To observe and appraise its clinical curative effect synthetically on LDVT treated by Kang MaiⅡcapsule.
Methods:we selected 30 patients treated by Kang MaiⅡcapsule as therapeutic group and other 30 patients treated by Tongsaimai tablet as control group.The symptoms and physical sign,the remark of hemanalysis and ET-1,6-K-PGF_1αwere detacted before treatment group.
Results:The therapeutic group total effective rate was 93.33%,while the control group total effective rate was 73.33%,with statistics analysis, the different between the two groups was significant.
Conlusion:We can draw a conclusion that Kang MaiⅡcapsule plays a positive role in the treatment of LDVT,and there is more effctive than Tongsaimai tablet.
引文
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[6]王健,李维军.中西医结合治疗下肢深静脉血栓形成42例疗效观察[J].新中医,2005,37(7):65-66
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[8]高峰,穆晓红.中西医结合治疗下肢深静脉血栓形成56例临床观察[J].四川中医,2007,25(8):90-91
[9]周翠红,杨林.中西医结合治疗下肢深静脉血栓形成的临床观察[J].辽宁中医杂志,2007,34(9):1233-1234
[10]方俐.中西医结合治疗下肢深静脉血栓形成46例[J].山西中医,2002,18(2):39
[11]阴广先,张淑芳,孙忠举.中西医结合治疗下肢深静脉血栓形成28例疗效分析[J].工企医刊,2003,16(2):46-47
[12]陈辉.中西医结合治疗下肢深静脉血栓形成48例[J].中国中医急症,2006,15(1):7
[13]彭宏,王化京.中西医结合治疗下肢深静脉血栓形成36例[J].国医论坛,2007,22(1):29-30
[14]张练,杜丽苹.中西医结合治疗下肢深静脉血栓形成231例[J].山东中医杂志,2003,22(6):358-359
[15]秦有,麦秀钧,陈经宝,等.中西医结合治疗下肢深静脉血栓形成68例疗效观察[J].四川中医,2008,26(8):100-101
[16]杜全胜,张建强.中西医结合分期治疗下肢深静脉血栓形成48例[J].河北医药, 2000,22(6):467-468
[17]王朝生,刘昌华,田诗政,等.中西医结合治疗下肢深静血栓30例[J].湖北中医杂志,1999,21(4):162-163
[18]张延杰,王 红.中西医结合治疗下肢深静脉血栓形成28例临床观察[J].山东医药,2000,40(14):61
[19]荆淑红,张丽.中西医结合治疗下肢深静脉血栓形成45例[J].中国中医药信息杂志,2004,11(6):535-536
[20]侯玉芬,陈柏楠.中西医结合治疗下肢深静脉血栓形成311例分析[J].医学研究通讯,1997,26(3):39-41.
[21]李晨,等.针灸治疗下肢血栓性深静脉炎案[J].中国针灸,1996,16(10):31
[22]潘进社,李玲,朱燕彩.理疗对骨折并下肢血栓性静脉炎的治疗作用[J].河北医科大学学报,1997,18(4):230.
[23]牛晓,吕陪文.葛根素注射液治疗下肢深静脉血栓后综合征临床疗效[J].中国新药杂志,1999,8(11):759.
[24]王静,范吾凤.中药外敷治疗下肢深静脉血栓形成30例[J].中医外治杂志,2002,11(3):11.
[25]孙平良,唐乾利,张力,等.熏洗疗法在下肢深静脉血栓形成中的应用[J].中国中医药信息杂志,2006,13(6):75-76
[26]荆淑红.活血消肿散辅助治疗下肢深静脉血栓形成52例[J].山东中医杂志,2004,23(6):346-347.
[27]邱德健.中西医结合治疗下肢深静脉血栓形成25例[J].浙江中西医结合杂志,2000,10(4):231.
[28]王凤莲,李玉幸,王湃.下肢深静脉血栓形成的病因探讨[J].宁夏医学杂志,1999,21(4):213-214
[29]徐浩,祖茂衡,顾玉明,等.髂股深静脉血栓形成相关解剖研究及经颈静脉介入治疗[J].介入放射学杂志,1997,6(3):130-132.
[30]赵军,董国祥.左髂总静脉狭窄与急性下肢深静脉血栓形成[J].中华外科杂志,1998,36(1):12-14.
[31]S.K.klein,E.J.slim,M.D de kruif,et al.Is chronic HIV infection associated with venous thrombotic disease? A systematic review.The NewEngland journal of medicine, 2005,63:129.
[32]王振义.血液的凝固和抗凝.见:兰锡纯主编.心脏血管外科学.下册[M].第1版.北京:人民卫生出版社,1984:45.
[33]薛冠华.静脉血栓形成与抗活化蛋白C现象.国外医学外科学分册,2000,27:91.
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