情志干预配合加味痛泻要方治疗D-IBS肝郁脾虚证的临床研究
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摘要
目的：观察情志干预配合加味痛泻要方治疗D-IBS肝郁脾虚证的临床疗效。
方法：60例D-IBS肝郁脾虚证病人,随机分为情志干预配合加味痛泻要方治疗组(简称综合治疗组)20例,加味痛泻要方治疗组(简称治疗组)20例,安慰剂治疗组(简称安慰剂组)20例。三组疗程均为4周,治疗结束后观察其临床疗效及精神心理学评定疗效。
结果：1、综合治疗组20例,临床有效率100%；治疗组20例,临床有效率75%；安慰剂治疗组临床有效率40%,三组临床疗效比较,经统计学处理,差异有统计学意义(P<0.01),提示：三组均能改善肠易激综合征疾病疗效,且综合治疗组在改善疾病疗效上优于治疗组和安慰剂组。
2、治疗后三组患者中医症状总积分比治疗前差异有统计学意义(P<0.01)；提示：三组均能改善中医证候,且综合治疗组在改善中医症状总积分上明显优于治疗组和安慰剂组(P<0.01)
3、综合治疗组在改善大便泄泻、腹痛、抑郁或烦躁、食欲不振和嗳气症状上优于治疗组和安慰剂组。
4、综合治疗组治疗D-IBS能明显提高临床疗效,有效改善临床症状且无副作用等优点。
结论：情志干预配合加味痛泻要方治疗D-IBS肝郁脾虚证有显著的疗效,是一有效的治疗方法,值得临床推广。
Objective:Observe the clinical curative effect of sentiment intervention with flavored Txyf treat sore stomach irritable bowel syndrome of the spleen deficiency.
Method:60 cases irritable bowel syndrome, spleen deficiency stomach patients were randomly divided into sentiment intervention with flavored Txyf group (the following is called Comprehensive treatment group) 20 patients,flavored Txyf treatment group (the following is called treatment group) 20 patients, placebo treatment group (the following is called controls) 20 cases. Three groups of treatment by 4 weeks, after the treatment observed the clinical enteron symptom curative effect and the efficacy of the spiritual psychology group.
Result:1. Comprehensive treatment group of 20 cases, clinical efficient 100%; 20 cases in treatment group, clinical efficient 75%; A placebo group of clinical efficient 40%, three groups of clinical curative effect comparison, by statistical processing, has significant difference (P< 0.01), Tip:three groups all can improve irritable bowel syndrome disease curative effect, and in improving comprehensive treatment group more than the disease curative effect treatment group and placebo group.
2.Three groups of patients after the treatment of TCM symptoms than before treatment are total score was significant difference (P< 0.01), Tip: three groups all can improve syndromes, and in improving TCM symptoms of sentiment group total score on obviously superior treatment group and placebo groups (P<0.01)
3. Comprehensive treatment group in improving defecate diarrhea, abdominal pain, depression or irritable and appetite and belch symptoms superior treatment group and placebo.
4. Comprehensive treatment treatment group D-IBS can obviously increase the clinical curative effect, effectively improve the clinical symptoms and no side effects, etc.
Conclusion:sentiment intervention with flavored Txyf therapy for irritable bowel syndrome stomach spleen deficiency significantly curative effect, is an effective treatment methods, is worthy to be popularized.
方法：60例D-IBS肝郁脾虚证病人,随机分为情志干预配合加味痛泻要方治疗组(简称综合治疗组)20例,加味痛泻要方治疗组(简称治疗组)20例,安慰剂治疗组(简称安慰剂组)20例。三组疗程均为4周,治疗结束后观察其临床疗效及精神心理学评定疗效。
结果：1、综合治疗组20例,临床有效率100%；治疗组20例,临床有效率75%；安慰剂治疗组临床有效率40%,三组临床疗效比较,经统计学处理,差异有统计学意义(P<0.01),提示：三组均能改善肠易激综合征疾病疗效,且综合治疗组在改善疾病疗效上优于治疗组和安慰剂组。
2、治疗后三组患者中医症状总积分比治疗前差异有统计学意义(P<0.01)；提示：三组均能改善中医证候,且综合治疗组在改善中医症状总积分上明显优于治疗组和安慰剂组(P<0.01)
3、综合治疗组在改善大便泄泻、腹痛、抑郁或烦躁、食欲不振和嗳气症状上优于治疗组和安慰剂组。
4、综合治疗组治疗D-IBS能明显提高临床疗效,有效改善临床症状且无副作用等优点。
结论：情志干预配合加味痛泻要方治疗D-IBS肝郁脾虚证有显著的疗效,是一有效的治疗方法,值得临床推广。
Objective:Observe the clinical curative effect of sentiment intervention with flavored Txyf treat sore stomach irritable bowel syndrome of the spleen deficiency.
Method:60 cases irritable bowel syndrome, spleen deficiency stomach patients were randomly divided into sentiment intervention with flavored Txyf group (the following is called Comprehensive treatment group) 20 patients,flavored Txyf treatment group (the following is called treatment group) 20 patients, placebo treatment group (the following is called controls) 20 cases. Three groups of treatment by 4 weeks, after the treatment observed the clinical enteron symptom curative effect and the efficacy of the spiritual psychology group.
Result:1. Comprehensive treatment group of 20 cases, clinical efficient 100%; 20 cases in treatment group, clinical efficient 75%; A placebo group of clinical efficient 40%, three groups of clinical curative effect comparison, by statistical processing, has significant difference (P< 0.01), Tip:three groups all can improve irritable bowel syndrome disease curative effect, and in improving comprehensive treatment group more than the disease curative effect treatment group and placebo group.
2.Three groups of patients after the treatment of TCM symptoms than before treatment are total score was significant difference (P< 0.01), Tip: three groups all can improve syndromes, and in improving TCM symptoms of sentiment group total score on obviously superior treatment group and placebo groups (P<0.01)
3. Comprehensive treatment group in improving defecate diarrhea, abdominal pain, depression or irritable and appetite and belch symptoms superior treatment group and placebo.
4. Comprehensive treatment treatment group D-IBS can obviously increase the clinical curative effect, effectively improve the clinical symptoms and no side effects, etc.
Conclusion:sentiment intervention with flavored Txyf therapy for irritable bowel syndrome stomach spleen deficiency significantly curative effect, is an effective treatment methods, is worthy to be popularized.
引文
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