女性乳腺恶性肿瘤住院患者医护需求及影响因素的研究
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摘要
第一篇女性乳腺恶性肿瘤住院患者医护需求量表的编制及信效度考评
     目的:编制适合中国文化背景和语言习惯的乳腺恶性肿瘤住院患者需求量表。检验编制量表的信度和效度。
     方法:在马斯洛需求模型和新型医学模式的指导下,广泛查阅国内外文献,参考国外需求量表,对医务人员和患者进行访谈,听取专家小组的意见,构建量表的基本框架,形成初始测试量表。采用随机整群抽样的方法,使用初始测试量表调查了115名住院治疗的乳腺癌患者,通过专家评分法、应答率、t检验法、相关系数法、变异度法、反应度法、多元线性回归分析法、克朗巴赫系数法、因子分析法等方法进行条目分析,保留条目形成乳腺恶性肿瘤住院患者医护需求量表测试版,并使用重测信度、克朗巴赫系数、分半信度、内容效度、结构效度、区分效度、效标关联效度等方法考察量表的信度和效度。
     结果:初始测试量表具有64个条目,使用8种方法进行条目筛选,保留被6种以上方法选中的条目,调整保留了性知识维度的3个条目,最终形成了具有38个条目,疾病知识、环境、性知识、情感4个维度的测试量表,与理论构想一致。4个维度和总分的重测信度分别为0.791、0.815、0.753、0.632和0.781;克朗巴赫系数分别为0.914、0.889、0.879、0.936和0.959。各个维度的分半信度在0.837-0.918之间,总量表的分半信度是0.935。使用主成分因子分析法提取4个公因子,并使用正交旋转法进行因子旋转,共解释总变异的58.605%。情感维度有16个条目,方差贡献率为18.866%;知识维度有12个条目,方差贡献率为16.329%;环境需求维度共计7个条目,方程贡献率为15.467%;性知识维度有3个条目;方差贡献率为7.944%。使用结构方程绘制了4个维度和总量表的路径图,模型适配良好,5个模型的AIC值均小于饱和模型和独立模型。条目与所在维度的相关系数均大于与其它维度的相关系数,维度之间的相关系数在0.213-0.564之间,维度与总分的相关系数在0.499-0.778之间。使用数据方程构建4个维度之间的6个关系模型,显示6个组合的未限制模型与限制模型的卡方差异值均有显著的不同,4个维度的维度划分区分效度良好。4个维度以及总分与简易满意度量表的相关系数为-0.371、-0.315、-0.241、-0.261和-0.353。与欧洲乳腺癌症患者生活质量特异量表的相关系数为-0.310-0.402之间。
     结论:乳腺恶性肿瘤住院患者医护需求量表是可靠的、灵敏的、有效的、具有独立性和代表性,可以作为乳腺癌患者需求的测量工具应用于医疗实践。
     第二篇女性乳腺恶性肿瘤住院患者医护需求及影响因素研究
     目的:了解我国乳腺恶性肿瘤患者的需求现状,探讨需求的影响因素,为患者医疗护理和健康教育工作提供参考。
     方法:采用随机抽样的方法抽取调查对象,使用一般人口学资料问卷、临床资料问卷和自编的乳腺恶性肿瘤住院患者医护需求量表对住院治疗的乳腺恶性肿瘤患者进行调查。采用SP免疫组织化学染色方法检测被调查者乳腺组织的雌激素受体、孕激素受体和人表皮生长因子受体2的表达。使用两样本t检验比较不同治疗阶段、年龄组、工作状态、手术方式患者需求在不同维度得分和总量表的得分。使用单因素方差分析比较不同人均月收入、文化程度、家庭结构、付款方式、病理表达和不同免疫组化分类的患者需求在不同维度和量表的得分。将量表的总分、知识维度、环境维度、性知识维度、情感维度的需求得分作为因变量,采用多元线性回归分析的逐步选择法探讨需求的影响因素,其中a入=0.05,a出=0.10。使用结构方程模型绘制4个维度和总量表与可能影响因素的路径图。
     结果:需求量表的总分为63.433±17.132,知识、环境、性知识和情感四个维度的得分分别为65.615±20.854、67.636±20.131、42.854±28.640、63.743±18.334。性知识维度得分显著低于其它维度,环境维度高于情感维度。年轻患者性知识需求较高;处于手术治疗阶段的患者对疾病知识需求、环境需求和情感需求较高;人均月收入高的患者在环境需求和情感需求较其他人群高;独居患者的知识需求明显低于其它家庭结构的患者;处于全休状态的患者在知识、环境和总需求的得分显著高于处于工作状态的患者;参加新型农村医疗的患者的环境、情感和总的需求低于其它付款方式的患者,ER和PR表达阳性的患者环境、情感和总的需求高于表达阴性的患者。获得需求信息的主要方式为知识宣传手册、与医务人员面对面交流和从电视节目中获得信息。患者的需求受多种因素影响,工作状态、人均月收入、使用中药治疗、治疗所处阶段、ER的表达是总需求的影响因素;工作状态、人均月收入、治疗所处阶段是知识需求的影响因素;工作状态、人均月收入、治疗所处阶段、ER的表达是环境需求的影响因素;年龄和人均月收入是性知识需求的影响因素;PR的表达和人均月收入是情感需求的影响因素。结构方程在4个维度和量表共拟合了8个路径图,8个模型的所有的卡方自由度比均小于2.5,CFI值均大于0.85,NFI值均大于0.80,RMSEA均小于0.08,P值均大于0.05,模型拟合良好。
     结论:对于不同的患者给予不同的需求关注:年轻的患者性知识需求;手术治疗阶段患者的知识、环境和情感需求;人均月收入高患者的环境和情感需求;全休患者的知识、环境需求;医疗费用保障好患者的环境和情感需求。需求的影响因素主要有调查时工作状态、人均月收入、治疗所处阶段和雌激素受体的表达。医务人员应主动给予年老、低收入、接受化放疗治疗和免疫组化染色结果阴性的患者更多的健康教育。
Chapter one:Development of the demand scale in female breast cancer hospitalized patients and evaluation of reliability and validity
     Objective:To develop a demand scale in Chinese and test the reliability and validity.
     Methods:On the basis of Maslow's model and the new medical model, we read the foreign and domestic papers, refer to foreign demand tables, interviews with medical staff and patients, follow the suggestions of the experts, make the frame of scale. After these, the original table was made.115inpatient breast cancer patients were chosen to test the initial scale randomly. More than10methods were used to analysis the initial scale, including experts importance score, response rate, t-test, correlation coefficient, method variability, responsiveness analysis, stepwise regression analysis, Cronbach's coefficient. The remaining entries form the breast cancer beta sheet, the reliability and validity were tested by test-retest reliability, Cronbach's coefficient, split-half reliability, content validity, construct validity, discriminant validity criterion-related validity testing methods and so on.
     Results:Original scale has64items, which was analyzied by10methods. There were8methods where items were deleted. The items were chosen if selected by more than6methods,3items in sex knowledge dimension were adjusted and retained. The scale had38items and4dimension including disease knowledge, environment needs, knowledge needs, Psychological needs of the investigation. The scale was consistent with theoretical ideas. The four dimensions and scale of the test-retest reliability score was0.791、0.815.0.753.0.632and0.781respectively. Cronbach's coefficients were0.914.0.889.0.879.0.936and 0.959. Every dimensions of split-half reliability varied between0.837to0.913, total scale split-half reliability were0.935. Principal component factor analysis was used to extract four common factors; the orthogonal rotation method was used for factor rotation,58.605%of total variance can be explained.Psychological dimensions had16items, the variance contribution rate was19.203%.Disease knowledge dimension has12items, variance contribution was17.359%. environment demand dimension had7items, the contribution rate was12.576%. Sex knowledge dimension had3items, variance contribution was7.944%.Four dimensions and total scale of the path map were drawn with equation, the model fit well,5model AIC values were less than the saturated model and independent model. The correlation coefficients between the items and its dimension was significant than the correlation with other dimensions, the correlation coefficients varied between0.213and0.564. The dimensions and total score correlation coefficients were between0.499and0.778. Equations were used to build six relationships between four dimensions, which showed six combinations unrestricted model and restricted models were significantly different, the four dimensions had good discriminate validity. The correlated factors between four dimensions and the total and simple satisfaction scale score were-0.371、-0.315.-0.241、-0.261and-0.353. The correlation coefficient factors with European quality of life scale for breast cancer patients were between-0.310and0.402.
     Conclusion:The demand scale for Breast cancer patients demand is reliable, sensitive and effective, it is independent and representative, which can serve as a tool for breast cancer patient needs analysis and be used in clinical practice as a supplement for clinical diagnosis and treatment.
     Chapter two:Health care Demand and Influence factors of Demand in female breast cancer hospitalized patients
     Objective:To find the needs condition of breast cancer in China and explore the influence factors of demand. Provide a reference for health education.
     Methods:To investigate the breast cancer patients with self made scale including general demographic scale, clinical data questionnaire and breast cancer demand scale. To test estrogen receptor, progesterone receptor and human epidermal growth factor receptor2expression with SP immunohistochemical staining. T-test was used to compare the difference of demand in different stages of treatment, different age groups, different working conditions, and different surgical procedures. The one way variance analysis was used to compare the difference of patient needs in different family incomes, different education levels, different marital status, different payment ways, different pathological expression, different surgical methods and different classification of immunohistochemical expression. Multiple linear regression was used to explore the influence factors in the scale score, disease knowledge dimensions scores, physical dimensions score, dimensions of sex knowledge, social and psychological dimensions of score, ain=0.05, aout=0.10. Structural equation was used to build the reod map between dimensions, scale and influence factors.
     Results:The total score of demand scale is63.433±17.132, the score of disease knowledge, physical needs, sex knowledge needs and psychosocial needs were65.615±20.854,67.636±20.131,42.854±28.640, and63.743±18.334individually. Sex knowledge score was significantly lower than other dimensions, the environment needs were more than emotional needs. Young patients had stronger knowledge than old patients. Patients in operative period had higher scores than in chemotherapy or radiotherapy in disease knowledge needs, physical needs and psychosocial needs. Patients with high family income had higher needs than other groups in environment needs and psychological needs. Knowledge needs of patients living alone were significantly lower than patients with other family structures. Knowledge、environment and total needs in patients at rest were significantly higher than patient working. Environment、emotional and total needs in patients who participate new rural medical care were lower than patients with other payment methods. Environmental、emotional and total needs in patients with ER and PR positive expression were higher than patients with ER and PR negative expression. The main way to obtain demand were information brochures for the knowledge, the medical staff face to face and get information from television programs. The needs of patients were affected by many factors, including Work status, family income, whether to use traditional Chinese medicine, treatment of the stage, ER expression. Work status, family income, the treatment stages were influence factors of disease knowledge needs. Work status, family income, the treatment stages, ER expression were the influence factors in physical needs. Age and family income were influence factors in sex knowledge needs. PR expression and family income were the influence factors in psychosocial demands.There are8maps in the scale and four dimensions. All the values between chi-square degrees and freedom are less than2in all the8models. All CFI values are greater than0.90, all NFI values greater than0.90, all RMSEA values are less than0.08, all P values are greater than0.05, models are good settled.
     Conclusions:The doctors should pay different attention to need to different patients. Younger patients had stronger knowledge needs. Surgical patients had more disease knowledge needs. Patients with high monthly income had high physical needs and psychological needs than in other groups. Patients at rest had more knowledge needs and environmental needs. Patients who had good medical care had more environmental and emotional needs. The influencing factors of needs had working status、family income、treatment stage and ER expression. More active health education should be given in old, low income, young, surgical patients, and immunohistochemical negative expression patients.
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