球囊扩张椎体后凸成形术治疗新鲜骨质疏松性脊柱压缩骨折的临床疗效观察
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摘要
目的:回顾并总结球囊扩张椎体后凸成形术治疗新鲜骨质疏松性椎体压缩骨折的临床疗效,手术适应症、并发症及相关操作要点。
方法:回顾性分析大连医科大学附属第二医院2007～2009年间,应用球囊扩张椎体后凸成形术治疗新鲜骨质疏松性胸腰椎压缩性骨折并获得随访3个月以上的20例患者的临床资料,其中男性5例,女性15例。年龄50～80岁,平均64岁。病程1～15天。平均3天。本组均为单椎体骨折,部位T12椎体2例、L1椎体5例、L2椎体4例、L3椎体3例、L4椎体4例、L5椎体2例。手术方式:经皮球囊扩张椎体后凸成形术,采用经双侧椎弓根途径球囊扩张成形系统。采用疼痛强度评价的视觉类比评(Visual Analogue Scale,VAS)VAS评分及手术前后病椎形态变化对比,对术后疗效及相关因素进行讨论分析。
结果:
1.平均随访时间13个月(3～24个月)。采用电话或门诊随访。
2.VAS评分:术前7～9分,平均8.33分,术后0～4分,平均为2.45分,手术前后有显著差异(P<0.01)。
3.病椎形态变化情况:椎体前缘高度术前为0.8～2.4cm,平均为1.85cm,术后为1.4～3.0cm,平均为2.43cm,手术前后差异有显著性(P<0.01)。椎体中间高度术前为1.3～2.5cm,平均为2.03cm,术后为1.7～2.8cm,平均为2.54cm,手术前后差异有显著性(P<0.01)。椎体后缘高度术前为2.5～3.4cm,平均为2.95cm,术后为2.5～3.5cm,平均为3.01cm,手术前后差异无显著(P>0.05)。
结论:球囊扩张椎体后凸成形术治疗新鲜骨质疏松性椎体压缩骨折止痛效果确切,椎体高度能不同程度得到恢复,操作简便。
Objective:To look back and sum up the expansion balloon kyphoplasty treatment of fresh osteoporotic vertebral compression fractures in clinical efficacy, surgical indications, complications and related operating elements. Methods:Retrospective analysis of Second Affiliated Hospital of Dalian Medical University between 2007-2009,the application of balloon kyphoplasty to expand the treatment of fresh osteoporotic thoracolumbar vertebral compression fractures and more than 3 months follow-up of 20 cases of patients with clinical data,including five cases of male,female 15 cases.Age 50-80 years old,an average of 64 years.Course of 1-15 days.An average of 3 days.In this group are single vertebral fracture,2 cases of parts of T12 vertebral body,L1 vertebral body in 5 cases,L2 vertebral body in 4 cases,L3 vertebral body in 3 cases,L4 vertebral body in 4 cases,L5 vertebral body in 2 cases.Surgical approach:the expansion of percutaneous balloon kyphoplasty using bilateral pedicle by means of balloon mitral system. Evaluation of pain intensity using visual analogue assessment (Visual Analogue Scale,VAS) VAS score and surgical disease of vertebral morphological changes before and after comparison of the efficacy and after discussion and analysis of relevant factors.
Results:
1. The average follow-up period was 13 months(3-24 months).Using the telephone or out-patient follow-up.
2. VAS score:7-9 hours preoperatively,with an average 8.33 points,after 0 to 4 points,an average of 2.45 points,before and after surgery were significantly different(P <0.01).
3. Morphological changes in vertebral disease:preoperative vertebral body height front for 0.8-2.4 cm,an average of 1.85 cm,after for 1.4-3.0cm, an average of 2.43 cm,before and after surgery there was a significant difference(P <0.01).Preoperative vertebral body height to the middle of 1.3-2.5cm,an average of 2.03cm,after for the 1.7-2.8cm,an average of 2.54 cm,before and after surgery there was a significant difference(P <0.01). Margin of vertebral body height after the surgery before the 2.5-3.4 cm,an average of 2.95 cm,after for the 2.5-3.5cm,an average of 3.01cm,before and after surgery there was no significant difference(P> 0.05).
Conclusion:Balloon Kyphoplasty to expand the treatment of new osteoporotic vertebral compression fractures precise analgesic effect, vertebral height can be restored to varying degrees,easy to operate.
方法:回顾性分析大连医科大学附属第二医院2007～2009年间,应用球囊扩张椎体后凸成形术治疗新鲜骨质疏松性胸腰椎压缩性骨折并获得随访3个月以上的20例患者的临床资料,其中男性5例,女性15例。年龄50～80岁,平均64岁。病程1～15天。平均3天。本组均为单椎体骨折,部位T12椎体2例、L1椎体5例、L2椎体4例、L3椎体3例、L4椎体4例、L5椎体2例。手术方式:经皮球囊扩张椎体后凸成形术,采用经双侧椎弓根途径球囊扩张成形系统。采用疼痛强度评价的视觉类比评(Visual Analogue Scale,VAS)VAS评分及手术前后病椎形态变化对比,对术后疗效及相关因素进行讨论分析。
结果:
1.平均随访时间13个月(3～24个月)。采用电话或门诊随访。
2.VAS评分:术前7～9分,平均8.33分,术后0～4分,平均为2.45分,手术前后有显著差异(P<0.01)。
3.病椎形态变化情况:椎体前缘高度术前为0.8～2.4cm,平均为1.85cm,术后为1.4～3.0cm,平均为2.43cm,手术前后差异有显著性(P<0.01)。椎体中间高度术前为1.3～2.5cm,平均为2.03cm,术后为1.7～2.8cm,平均为2.54cm,手术前后差异有显著性(P<0.01)。椎体后缘高度术前为2.5～3.4cm,平均为2.95cm,术后为2.5～3.5cm,平均为3.01cm,手术前后差异无显著(P>0.05)。
结论:球囊扩张椎体后凸成形术治疗新鲜骨质疏松性椎体压缩骨折止痛效果确切,椎体高度能不同程度得到恢复,操作简便。
Objective:To look back and sum up the expansion balloon kyphoplasty treatment of fresh osteoporotic vertebral compression fractures in clinical efficacy, surgical indications, complications and related operating elements. Methods:Retrospective analysis of Second Affiliated Hospital of Dalian Medical University between 2007-2009,the application of balloon kyphoplasty to expand the treatment of fresh osteoporotic thoracolumbar vertebral compression fractures and more than 3 months follow-up of 20 cases of patients with clinical data,including five cases of male,female 15 cases.Age 50-80 years old,an average of 64 years.Course of 1-15 days.An average of 3 days.In this group are single vertebral fracture,2 cases of parts of T12 vertebral body,L1 vertebral body in 5 cases,L2 vertebral body in 4 cases,L3 vertebral body in 3 cases,L4 vertebral body in 4 cases,L5 vertebral body in 2 cases.Surgical approach:the expansion of percutaneous balloon kyphoplasty using bilateral pedicle by means of balloon mitral system. Evaluation of pain intensity using visual analogue assessment (Visual Analogue Scale,VAS) VAS score and surgical disease of vertebral morphological changes before and after comparison of the efficacy and after discussion and analysis of relevant factors.
Results:
1. The average follow-up period was 13 months(3-24 months).Using the telephone or out-patient follow-up.
2. VAS score:7-9 hours preoperatively,with an average 8.33 points,after 0 to 4 points,an average of 2.45 points,before and after surgery were significantly different(P <0.01).
3. Morphological changes in vertebral disease:preoperative vertebral body height front for 0.8-2.4 cm,an average of 1.85 cm,after for 1.4-3.0cm, an average of 2.43 cm,before and after surgery there was a significant difference(P <0.01).Preoperative vertebral body height to the middle of 1.3-2.5cm,an average of 2.03cm,after for the 1.7-2.8cm,an average of 2.54 cm,before and after surgery there was a significant difference(P <0.01). Margin of vertebral body height after the surgery before the 2.5-3.4 cm,an average of 2.95 cm,after for the 2.5-3.5cm,an average of 3.01cm,before and after surgery there was no significant difference(P> 0.05).
Conclusion:Balloon Kyphoplasty to expand the treatment of new osteoporotic vertebral compression fractures precise analgesic effect, vertebral height can be restored to varying degrees,easy to operate.
引文
1.曹渊武,陈统一,姜晓幸.经皮球囊扩张椎体后凸成形术及其发展.国际骨科学杂志,2008,29(2):120-122.
2.朱贤康,钟家云,廖永发.经皮球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩性骨折.微创医学,2008,3(5):466-468.
3.陈建明,张成程,许天明,等.经皮球囊扩张椎体后凸成形术治疗骨质疏松性脊柱压缩性骨折.颈腰痛杂志,2008,29(4):338-339.
4.袁宏,王利,王浩,等.经皮球囊扩张椎体后凸成形术的临床应用.脊柱外科杂志,2006,4(6):367-368.
5. Arnar AP,larsen DW,tdbatiyfl GP,et a1.Neurosurgery,2003: 53(2):38O-383.
6. Tomita S,Molloy S,Jasper LE,et o1.spine.2004;29(11):1203 -1207
7.陈建庭,肖颖,金大地,等.骨质疏松椎体压缩性骨折经皮椎体成形术后Cobb角继发增大的危险因素分析.南方医科大学学报,2008,28(8)1428-1430.
8.郑召民,李佛保.经皮椎体成形术和经皮椎体后凸成形术——问题与对策.中华医学杂志,2006,86(27):1878-1880.
9.郑召民.经皮椎体成形术和经皮椎体后凸成形术灾难性并发症——骨水泥渗漏及其预防.中华医学杂志,2006,86(43):3027-3030.
10. HdkoffSM,Mathis JM,FentoaDC,et a1.spine,200b 26(2):151-156.
11. Belkoff SM,Jasper LE,Steverkq SS spine,2002;27(15):1640-1643
12.宁飞鹏,陈博来,林定坤,等.经皮椎体成形术及经皮椎体后凸成形术中骨水泥渗漏原因探讨.广东医学,2008,29(1):166.
13.张德宏,李盛华,王想福,等.经皮椎体成形术及球囊扩张椎体后凸成形术的临床应用进展.中华实用中西医杂志,2008,21(12):905-909.
14.张龙君,张居适,叶锋,等.球囊扩张椎体后凸成形术操作技术的体会.浙江创伤外科,2008,13(5):445-446.
15. Belkoff SM,molloy S Spine,2003;28(14):155-1559
16. Togawa D,Bauer TW,Ijeherman IH,et a1.Spine,3203;7.8(14): 1521-1527
17.肖晟,黄象望,刘向阳,等.球囊扩张椎体后凸成形术治疗骨质疏松性椎体骨折的疗效分析.中国医学工程,2006,14(5):476-478.
18.张强,邹德威,海涌,等.球囊扩张椎体后凸成形术治疗骨质疏松压缩骨折的初步结果.中华创伤骨科杂志,2006,8(5):497-498.
19. Matsuyarm Y,Goto M,Yoshihara H,et a1.J spina sordTeeh. 2OO4;17(4):29l-296
20. Hitchon PW,Goel V,drake J,et a1.J Neurosurg,2001;95(2 Supp1) :215-220.
21.郑召民,邝冠明,董智勇,等.新型Vessel-X骨材料填充器经皮椎体成形术(Vesselplasty)——球囊扩张椎体后凸成形术的替代选择.中国微创外科杂志,2007,7(2):143-145.
22.贾中伟,苏云星,刘芳,等。椎体成形术和球囊椎体后凸成形术在骨质疏松性椎体压缩骨折中的应用与比较。山西医科大学学报, 2008年, 39(12):1142-1144.
23. Rhyne A 3rd,Banit D,IaxerE,et a1.J Orthop trauma,2004;18 (5);294-299
24. Gaitanis IN,Candang G.Phillips FM,et a1.Spine J,2005;5(1):45-54.
25. Villarraga MI,BdlezzaAJ,HarriganTP,et a1.J na1 Disord 1,2005;18.
1.贾连顺.现代脊柱外科学.人民军医出版社.2007.1233-1238.
2.王宇,邑晓东,吴志峰,等.eFilm影像工作站辅助PVP及PKP术前计划及术中定位的临床应用.中国脊柱脊髓杂志,2008,18(6):425-428.
3.李卫东,崔志明,保国锋,等.经皮椎体后凸成形术治疗骨质疏松性椎体骨折效果分析.南通大学学报,2007,27(5):375-377.
4.贾小林,杨阜滨,谭祖键,等.PVP与PKP治疗骨质疏松性骨折止痛效果分析.中国骨质疏松杂志,2009,15(1):53-55.
5. Choe DH,Marom EM,Ahrar K,et a1.Pulmonary embolism of polymethyl methacrylate during percutaneous vertebroplasty and kypho-plasty[J].Am J Roentgenol,2004,l83(4):1097-l102.
6. Duran C,Sirvanci M,Aydogan M,et a1.Pulmonary cement embolism:a complication of percutaneous vertebroplasty[J].Acta Radiol,2007,48(8):854 -859.
7. Hulme PA,Krebs J,Ferguson SJ,et al.Vertebroplasty and kyphoplasty:a systematic review of 69 clinical studies[J].Spine.2006.3l(17):1983-2001.
8. Katrien F,Yves T,Bart P,et a1.Successful management of a large pulmonary cement embolus after percutaneous vertebroplasty:a case report[J].Spine, 2003,28(20):E424-E425.
9.郑召民,李佛保.经皮椎体成形术和经皮椎体后凸成形术——问题与对策.中华医学杂志,2006,86(27):1878-1880.
10.郑召民.经皮椎体成形术和经皮椎体后凸成形术灾难性并发症——骨水泥渗漏及其预防.中华医学杂志,2006,86(43):3027-3030.
11.杨缚龙,李义刚,黎斐文,等.经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折.生物骨科材料与临床研究,2008,5(3):46-47.
12.范海泉,俞阳,曾祥嘉,等.经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折.脊柱外科杂志,2008,6(4):197-199.
13.白龙,叶珂,陈亮清,等.经皮椎体后凸成形术治疗老年骨质疏松性脊柱压缩骨折38例.医学综述,2008,14(16):2535-2537.
14.苏连澍.经皮椎体后凸成形术的研究应用进展.河北医学,2005,11(10):956-958.
15.李卫东,崔志明,保国锋,等.经皮椎体后凸成形术治疗骨质疏松性椎体骨折效果分析.南通大学学报,2007,27(5):375-377.
16.朱贤康,钟家云,廖永发.经皮球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩性骨折.微创医学,2008,3(5):466-468.
17.宋毓鸿,谢晓勇,李平生,等.经皮球囊扩张椎体后凸成形术治疗椎体压缩性骨折的应用体会.中国骨与关节损伤杂志,2007,22(11):946-947.
18.张龙君,张居适,叶锋,等.球囊扩张椎体后凸成形术操作技术的体会.浙江创伤外科,2008,13(5):445-446.
19.张德宏,李盛华,王想福,等.经皮椎体成形术及球囊扩张椎体后凸成形术的临床应用进展.中华实用中西医杂志,2008,21(12):905-909.
20.贾中伟,苏云星,刘芳,等.椎体成形术和球囊椎体后凸成形术在骨质疏松性椎体压缩骨折中的应用与比较.山西医科大学学报,2008年,39(12):1142-1144.
21.孙辉,白波,钱东阳,等.导航精确定位下经皮注入骨水泥椎体成形的特点.中国组织工程研究与临床康复,2008,12(23):4450-4452.
22.张居适,佟杰,康维杰,等.经皮椎体后凸成形术治疗骨质疏松性椎体骨折的临床应用.中国骨与关节损伤杂志,2008,23(8):662-663.
23.唐海,戴贺,陈浩.经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折的疗效.中国脊柱脊髓杂志,2007,17(11):833-837.
24.包杰,李镇江,刘国雄,等.经皮椎体后凸成形术治疗老年胸腰椎骨折.中国现代手术学杂志,,2008,12(3):208-209.
25. Trumees E,Hilibrard A,Vaeeam AR Spine J,2004;4(2):218-229.
26. Aebli N,Medvet JK,Davis G,et o1.Fatembolism and acute hypotension duringvertebroplasty:an experimental study insheep[J].Spine,2002,27:460- 466.
27. Tomita S,Molloy S,Jasper LE,et o1.Spine,2004,29(11):1203-120.
28. Steinroann J,ngey CT,Cruz G,et a1.Spine,2005,30(2):201-205.
29. Galibert P,Deramond H,Rosat P,et a1.Preliminary note on the treatment of vertebral all~oma by percutaneous acrylicvertebroplasty [J].Neurochirurgie, 1987,33:166-168.
30. Iiebermem IH,Dudeney S,R6nhardt MK,et a1.Spine,2001;26(14):1631-1638.
2.朱贤康,钟家云,廖永发.经皮球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩性骨折.微创医学,2008,3(5):466-468.
3.陈建明,张成程,许天明,等.经皮球囊扩张椎体后凸成形术治疗骨质疏松性脊柱压缩性骨折.颈腰痛杂志,2008,29(4):338-339.
4.袁宏,王利,王浩,等.经皮球囊扩张椎体后凸成形术的临床应用.脊柱外科杂志,2006,4(6):367-368.
5. Arnar AP,larsen DW,tdbatiyfl GP,et a1.Neurosurgery,2003: 53(2):38O-383.
6. Tomita S,Molloy S,Jasper LE,et o1.spine.2004;29(11):1203 -1207
7.陈建庭,肖颖,金大地,等.骨质疏松椎体压缩性骨折经皮椎体成形术后Cobb角继发增大的危险因素分析.南方医科大学学报,2008,28(8)1428-1430.
8.郑召民,李佛保.经皮椎体成形术和经皮椎体后凸成形术——问题与对策.中华医学杂志,2006,86(27):1878-1880.
9.郑召民.经皮椎体成形术和经皮椎体后凸成形术灾难性并发症——骨水泥渗漏及其预防.中华医学杂志,2006,86(43):3027-3030.
10. HdkoffSM,Mathis JM,FentoaDC,et a1.spine,200b 26(2):151-156.
11. Belkoff SM,Jasper LE,Steverkq SS spine,2002;27(15):1640-1643
12.宁飞鹏,陈博来,林定坤,等.经皮椎体成形术及经皮椎体后凸成形术中骨水泥渗漏原因探讨.广东医学,2008,29(1):166.
13.张德宏,李盛华,王想福,等.经皮椎体成形术及球囊扩张椎体后凸成形术的临床应用进展.中华实用中西医杂志,2008,21(12):905-909.
14.张龙君,张居适,叶锋,等.球囊扩张椎体后凸成形术操作技术的体会.浙江创伤外科,2008,13(5):445-446.
15. Belkoff SM,molloy S Spine,2003;28(14):155-1559
16. Togawa D,Bauer TW,Ijeherman IH,et a1.Spine,3203;7.8(14): 1521-1527
17.肖晟,黄象望,刘向阳,等.球囊扩张椎体后凸成形术治疗骨质疏松性椎体骨折的疗效分析.中国医学工程,2006,14(5):476-478.
18.张强,邹德威,海涌,等.球囊扩张椎体后凸成形术治疗骨质疏松压缩骨折的初步结果.中华创伤骨科杂志,2006,8(5):497-498.
19. Matsuyarm Y,Goto M,Yoshihara H,et a1.J spina sordTeeh. 2OO4;17(4):29l-296
20. Hitchon PW,Goel V,drake J,et a1.J Neurosurg,2001;95(2 Supp1) :215-220.
21.郑召民,邝冠明,董智勇,等.新型Vessel-X骨材料填充器经皮椎体成形术(Vesselplasty)——球囊扩张椎体后凸成形术的替代选择.中国微创外科杂志,2007,7(2):143-145.
22.贾中伟,苏云星,刘芳,等。椎体成形术和球囊椎体后凸成形术在骨质疏松性椎体压缩骨折中的应用与比较。山西医科大学学报, 2008年, 39(12):1142-1144.
23. Rhyne A 3rd,Banit D,IaxerE,et a1.J Orthop trauma,2004;18 (5);294-299
24. Gaitanis IN,Candang G.Phillips FM,et a1.Spine J,2005;5(1):45-54.
25. Villarraga MI,BdlezzaAJ,HarriganTP,et a1.J na1 Disord 1,2005;18.
1.贾连顺.现代脊柱外科学.人民军医出版社.2007.1233-1238.
2.王宇,邑晓东,吴志峰,等.eFilm影像工作站辅助PVP及PKP术前计划及术中定位的临床应用.中国脊柱脊髓杂志,2008,18(6):425-428.
3.李卫东,崔志明,保国锋,等.经皮椎体后凸成形术治疗骨质疏松性椎体骨折效果分析.南通大学学报,2007,27(5):375-377.
4.贾小林,杨阜滨,谭祖键,等.PVP与PKP治疗骨质疏松性骨折止痛效果分析.中国骨质疏松杂志,2009,15(1):53-55.
5. Choe DH,Marom EM,Ahrar K,et a1.Pulmonary embolism of polymethyl methacrylate during percutaneous vertebroplasty and kypho-plasty[J].Am J Roentgenol,2004,l83(4):1097-l102.
6. Duran C,Sirvanci M,Aydogan M,et a1.Pulmonary cement embolism:a complication of percutaneous vertebroplasty[J].Acta Radiol,2007,48(8):854 -859.
7. Hulme PA,Krebs J,Ferguson SJ,et al.Vertebroplasty and kyphoplasty:a systematic review of 69 clinical studies[J].Spine.2006.3l(17):1983-2001.
8. Katrien F,Yves T,Bart P,et a1.Successful management of a large pulmonary cement embolus after percutaneous vertebroplasty:a case report[J].Spine, 2003,28(20):E424-E425.
9.郑召民,李佛保.经皮椎体成形术和经皮椎体后凸成形术——问题与对策.中华医学杂志,2006,86(27):1878-1880.
10.郑召民.经皮椎体成形术和经皮椎体后凸成形术灾难性并发症——骨水泥渗漏及其预防.中华医学杂志,2006,86(43):3027-3030.
11.杨缚龙,李义刚,黎斐文,等.经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折.生物骨科材料与临床研究,2008,5(3):46-47.
12.范海泉,俞阳,曾祥嘉,等.经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折.脊柱外科杂志,2008,6(4):197-199.
13.白龙,叶珂,陈亮清,等.经皮椎体后凸成形术治疗老年骨质疏松性脊柱压缩骨折38例.医学综述,2008,14(16):2535-2537.
14.苏连澍.经皮椎体后凸成形术的研究应用进展.河北医学,2005,11(10):956-958.
15.李卫东,崔志明,保国锋,等.经皮椎体后凸成形术治疗骨质疏松性椎体骨折效果分析.南通大学学报,2007,27(5):375-377.
16.朱贤康,钟家云,廖永发.经皮球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩性骨折.微创医学,2008,3(5):466-468.
17.宋毓鸿,谢晓勇,李平生,等.经皮球囊扩张椎体后凸成形术治疗椎体压缩性骨折的应用体会.中国骨与关节损伤杂志,2007,22(11):946-947.
18.张龙君,张居适,叶锋,等.球囊扩张椎体后凸成形术操作技术的体会.浙江创伤外科,2008,13(5):445-446.
19.张德宏,李盛华,王想福,等.经皮椎体成形术及球囊扩张椎体后凸成形术的临床应用进展.中华实用中西医杂志,2008,21(12):905-909.
20.贾中伟,苏云星,刘芳,等.椎体成形术和球囊椎体后凸成形术在骨质疏松性椎体压缩骨折中的应用与比较.山西医科大学学报,2008年,39(12):1142-1144.
21.孙辉,白波,钱东阳,等.导航精确定位下经皮注入骨水泥椎体成形的特点.中国组织工程研究与临床康复,2008,12(23):4450-4452.
22.张居适,佟杰,康维杰,等.经皮椎体后凸成形术治疗骨质疏松性椎体骨折的临床应用.中国骨与关节损伤杂志,2008,23(8):662-663.
23.唐海,戴贺,陈浩.经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折的疗效.中国脊柱脊髓杂志,2007,17(11):833-837.
24.包杰,李镇江,刘国雄,等.经皮椎体后凸成形术治疗老年胸腰椎骨折.中国现代手术学杂志,,2008,12(3):208-209.
25. Trumees E,Hilibrard A,Vaeeam AR Spine J,2004;4(2):218-229.
26. Aebli N,Medvet JK,Davis G,et o1.Fatembolism and acute hypotension duringvertebroplasty:an experimental study insheep[J].Spine,2002,27:460- 466.
27. Tomita S,Molloy S,Jasper LE,et o1.Spine,2004,29(11):1203-120.
28. Steinroann J,ngey CT,Cruz G,et a1.Spine,2005,30(2):201-205.
29. Galibert P,Deramond H,Rosat P,et a1.Preliminary note on the treatment of vertebral all~oma by percutaneous acrylicvertebroplasty [J].Neurochirurgie, 1987,33:166-168.
30. Iiebermem IH,Dudeney S,R6nhardt MK,et a1.Spine,2001;26(14):1631-1638.