参杞消渴汤治疗消渴病气阴两虚挟瘀证的临床研究
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摘要
目的:为观察参杞消渴汤治疗消渴病气阴两虚挟瘀证的临床疗效
方法:取符合消渴病气阴两虚挟瘀证诊断标准的患者60例,随机分成2组。治疗组30例,予参杞消渴汤加减水煎取汁150ml一次1剂,一日四次,三餐后20分钟及睡前口服。对照组30例,予参芪降糖颗粒(由人参、五味子、黄芪、山药、地黄、枸杞子组成)一次1g,一日3次口服。治疗组与对照组均以一个月为一个疗程,连续观察两个疗程。两组间在疾病、病程、年龄、性别上经统计处理无差异,具有可比性。观察2组治疗前后理化检查及临床症状改善情况。
结果:结果表明治疗组显效率43.33%,总有效率83.33%;对照组显效率23.33%,总有效率60%,经统计学处理,P<0.05,具有显著性差异,说明治疗组疗效明显优于对照组。治疗后对于病人糖代谢情况,包括空腹血糖,餐后2小时血糖,糖化血红蛋白有较好的改善,与治疗前相比P<0.01,与对照组相比P<0.01。均具有极显著性差异,说明治疗组对于改善糖代谢情况优于对照组;治疗组对于患者脂代谢情况与治疗前相比P<0.01与对照组相比P<0.05,有显著性差异,说明参杞消渴汤对于改善患者脂代谢情况优于参芪降糖颗粒组。
结论:在临床症状及各种理化检查结果等方面均优于参芪降糖颗粒,未见不良反应,说明参杞消渴汤安全可靠,是治疗消渴病气阴两虚挟瘀证的有效方剂,值得进一步开发和研究。
Purpose: To observe the parameters Qi Decoction Diabetes Diabetes Qi and Yin Deficiency with Blood Stagnation designate the clinical efficacy
Method: Get in line with Diabetes Qi and Yin Deficiency with Blood Stagnation designate diagnostic criteria 60 patients were randomly divided into 2 groups. The treatment group 30 cases, I Shenqi Diabetes Decoction Decoction juice 150ml once one a day four times, three meals a day and before going to bed 20 minutes after oral administration. Control group of 30 cases, I Shenqijiangtang particles (from ginseng, Schisandra, Astragalus, yams, ground yellow, the composition of medlar) one 1g, on the 1st 3 times orally. The treatment group and control group are one month for a course of treatment, continuous observation of two courses. Between the two groups of disease, course of disease, age and sex by statistical processing was no difference between comparable. Observed two groups before and after treatment the clinical symptoms of physical and chemical inspection and improve the situation.
Result: The results show that the efficiency of the treatment group were 43.33% and total effective rate was 83.33%; control group, markedly effective rate 23.33%, and the total effective rate was 60%, by statistical analysis, P <0.05, significant difference, indicating significantly better than the control treatment group group. Glucose metabolism after treatment for the patient, including fasting blood glucose, 2-hour postprandial blood glucose, glycated hemoglobin better improvement in comparison with those before treatment P <0.01, compared with control group P <0.01. All have very significantly different, indicating the treatment group for improving the glucose metabolism than the control group; treatment group for patients with lipid metabolism in comparison with those before treatment P <0.01 compared with control group P <0.05, significant difference, indicating Shenqi Diabetes soup for improving lipid metabolism in patients with superior group Shenqijiangtang particles
Conclusion: In the clinical symptoms and a variety of physical and chemical test results, etc. are better than Shenqijiangtang particles, no adverse reactions, indicating Shenqi Diabetes Tang safe and reliable, the treatment of Diabetes Qi and Yin Deficiency with Blood Stagnation designate a valid prescription, worthy of further development and research.
方法:取符合消渴病气阴两虚挟瘀证诊断标准的患者60例,随机分成2组。治疗组30例,予参杞消渴汤加减水煎取汁150ml一次1剂,一日四次,三餐后20分钟及睡前口服。对照组30例,予参芪降糖颗粒(由人参、五味子、黄芪、山药、地黄、枸杞子组成)一次1g,一日3次口服。治疗组与对照组均以一个月为一个疗程,连续观察两个疗程。两组间在疾病、病程、年龄、性别上经统计处理无差异,具有可比性。观察2组治疗前后理化检查及临床症状改善情况。
结果:结果表明治疗组显效率43.33%,总有效率83.33%;对照组显效率23.33%,总有效率60%,经统计学处理,P<0.05,具有显著性差异,说明治疗组疗效明显优于对照组。治疗后对于病人糖代谢情况,包括空腹血糖,餐后2小时血糖,糖化血红蛋白有较好的改善,与治疗前相比P<0.01,与对照组相比P<0.01。均具有极显著性差异,说明治疗组对于改善糖代谢情况优于对照组;治疗组对于患者脂代谢情况与治疗前相比P<0.01与对照组相比P<0.05,有显著性差异,说明参杞消渴汤对于改善患者脂代谢情况优于参芪降糖颗粒组。
结论:在临床症状及各种理化检查结果等方面均优于参芪降糖颗粒,未见不良反应,说明参杞消渴汤安全可靠,是治疗消渴病气阴两虚挟瘀证的有效方剂,值得进一步开发和研究。
Purpose: To observe the parameters Qi Decoction Diabetes Diabetes Qi and Yin Deficiency with Blood Stagnation designate the clinical efficacy
Method: Get in line with Diabetes Qi and Yin Deficiency with Blood Stagnation designate diagnostic criteria 60 patients were randomly divided into 2 groups. The treatment group 30 cases, I Shenqi Diabetes Decoction Decoction juice 150ml once one a day four times, three meals a day and before going to bed 20 minutes after oral administration. Control group of 30 cases, I Shenqijiangtang particles (from ginseng, Schisandra, Astragalus, yams, ground yellow, the composition of medlar) one 1g, on the 1st 3 times orally. The treatment group and control group are one month for a course of treatment, continuous observation of two courses. Between the two groups of disease, course of disease, age and sex by statistical processing was no difference between comparable. Observed two groups before and after treatment the clinical symptoms of physical and chemical inspection and improve the situation.
Result: The results show that the efficiency of the treatment group were 43.33% and total effective rate was 83.33%; control group, markedly effective rate 23.33%, and the total effective rate was 60%, by statistical analysis, P <0.05, significant difference, indicating significantly better than the control treatment group group. Glucose metabolism after treatment for the patient, including fasting blood glucose, 2-hour postprandial blood glucose, glycated hemoglobin better improvement in comparison with those before treatment P <0.01, compared with control group P <0.01. All have very significantly different, indicating the treatment group for improving the glucose metabolism than the control group; treatment group for patients with lipid metabolism in comparison with those before treatment P <0.01 compared with control group P <0.05, significant difference, indicating Shenqi Diabetes soup for improving lipid metabolism in patients with superior group Shenqijiangtang particles
Conclusion: In the clinical symptoms and a variety of physical and chemical test results, etc. are better than Shenqijiangtang particles, no adverse reactions, indicating Shenqi Diabetes Tang safe and reliable, the treatment of Diabetes Qi and Yin Deficiency with Blood Stagnation designate a valid prescription, worthy of further development and research.
引文
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