橄榄油（茉莉香精）微胶囊的制备及性能研究
|
摘要
本文以明胶、阿拉伯胶为壁材,橄榄油和茉莉香精为芯材,分别合成了具有润肤保健和香味功能的微胶囊,并通过浸轧方式将制备的微胶囊整理到织物上,制备了相应的功能织物,详细研究了各工艺参数对微胶囊性能的影响。通过光学显微镜及扫描电镜观察微胶囊表面形貌,用马尔文激光粒度仪测定了微胶囊的粒径及其分布,并采用索氏提取法测定微胶囊的含油率。
首先以橄榄油为芯材,制备具有缓释功能的橄榄油微胶囊。研究了交联剂用量、壁材浓度、复凝聚过程的pH值及芯材与壁材用量比等对微胶囊性能的影响。实验结果表明:交联剂用量为3ml,壁材浓度为3%,复凝聚过程的pH值为4.0,芯材与壁材用量比为1:1条件下制备的橄榄油微胶囊,其含油率达到60%,平均粒径为3~8μm,表面形态良好。将最佳工艺条件下制备的橄榄油微胶囊通过浸轧方式整理到棉织物上,研究预烘温度、焙烘温度及时间、整理剂固含量、整理剂与粘合剂比例等对棉织物性能影响。通过对整理后棉织物含油率、透气透湿等性能进行测试,对织物整理工艺进行优化。结果表明,棉织物最佳整理工艺条件如下:预烘温度70℃、焙烘温度120℃、焙烘时间1分钟、整理剂固含量为5%、整理剂与黏合剂的比例为1:1。整理后的棉织物含油率在2~5%,手感较好,不影响织物的白度,具有较好的缓释性能,并有一定的耐洗性,能够满足一般服用要求。
其次以茉莉香精为芯材,制备了香精微胶囊,考察了交联时间、芯材与壁材用量比、交联过程pH值、喷雾干燥进风温度等对微胶囊含油率、粒径大小及分布和微胶囊缓释性能的影响,确定了茉莉香精微胶囊制备的最佳工艺条件。并在此工艺条件下,将茉莉香精和橄榄油混合作为芯材,制备了复合型微胶囊。实验结果表明,茉莉香精微胶囊的最大含油率可以达到38%,平均粒径为6～10μm,整理后的棉布具有较好的缓释性能。而且整理后的织物具有较好的透气透湿性,其透气阻值为0.29 kPa?s/m,透湿量为10828 g/( m2?24h)。复合型香精微胶囊整理的织物的透气阻值为0.282 kPa?s/m,透湿量为10870 g/( m2?24h)。
In this paper, the functional microcapsules of skin-caring and flavor were prepared using gelatin and arabic gum as the wall materials and olive oil and jasmine oil as the core materials. The microcapsules were finished into fabric by padding to obtain functional fabric. The parameters influencing the properties of microcapsules were studied in detail. The morphology was observed by optical microscope and scanning electron microscope. The particle size and distribution were tested by laser particle size analyzer. The oil content of the microcapsules was analyzed through soxhlet extraction.
First the olive oil microcapsules with the function of slow-releasing were prepared. The process parameters, such as the dosage of the cross linker, concentration of the wall materials, pH adjustment rate and the ratio between core and wall materials, were analyzed in detail. The optimal process parameters were as follow: dosage of the cross linking agent was of 3ml, the concentration of wall materials was of 3%, the pH value of coacervation was 4.0 and the ratio of core/wall material was 1:1. The a oil content of microcapsules prepared at optimal process was up to 60% and the mean particle size was 3~8μm with good surface morphology. Olive oil microcapsules prepared with the best parameters were finished on cotton fabric through padding. The effect of pre-drying temperature, curing temperature and time, solid content of finishing agent, the ratio between finishing agent and adhesive agent were investigated. Through testing the drug-loading rate of olive oil in cotton fabric, breathable and moisture permeability, the optimum parameters were as follow: pre-drying temperature was 70℃, curing temperature was 120℃and time was 1min, solid content of finishing agent was 5%, the ratio between finishing agent and adhesive agent was 1:1. The oil content of cotton fabric was 2~5% and had a good touch feeling and whiteness. Its slow-release property tested with UV spectrophotometer was also good. Breathable and moisture permeability and washing fastness were satisfied to normal needs of fabrics.
The perfume microcapsules were prepared using the jasmine oil as the core materials. Cross linking time, the ratio of core to wall, pH and the inlet temperature of spray drying were studied to get the optimum process conditions. And the optimal parameters were used to embed jasmine essence and olive oil to get mix cores microcapsules. The results showed that the maximum oil content reached 38%, the mean particle size ranged 6~10μm, the cotton fabric finished has good slow release performance. The breathe freely moisture permeability of fabric finished were good and the air resistance is 0.29 kPa?s/m, the moisture permeability content is 10828g/(m2?24h). The air resistance of complex microcapsules is 0.282 kPa?s/m, its moisture permeability content is 10870 g/(m2?24h).
首先以橄榄油为芯材,制备具有缓释功能的橄榄油微胶囊。研究了交联剂用量、壁材浓度、复凝聚过程的pH值及芯材与壁材用量比等对微胶囊性能的影响。实验结果表明:交联剂用量为3ml,壁材浓度为3%,复凝聚过程的pH值为4.0,芯材与壁材用量比为1:1条件下制备的橄榄油微胶囊,其含油率达到60%,平均粒径为3~8μm,表面形态良好。将最佳工艺条件下制备的橄榄油微胶囊通过浸轧方式整理到棉织物上,研究预烘温度、焙烘温度及时间、整理剂固含量、整理剂与粘合剂比例等对棉织物性能影响。通过对整理后棉织物含油率、透气透湿等性能进行测试,对织物整理工艺进行优化。结果表明,棉织物最佳整理工艺条件如下:预烘温度70℃、焙烘温度120℃、焙烘时间1分钟、整理剂固含量为5%、整理剂与黏合剂的比例为1:1。整理后的棉织物含油率在2~5%,手感较好,不影响织物的白度,具有较好的缓释性能,并有一定的耐洗性,能够满足一般服用要求。
其次以茉莉香精为芯材,制备了香精微胶囊,考察了交联时间、芯材与壁材用量比、交联过程pH值、喷雾干燥进风温度等对微胶囊含油率、粒径大小及分布和微胶囊缓释性能的影响,确定了茉莉香精微胶囊制备的最佳工艺条件。并在此工艺条件下,将茉莉香精和橄榄油混合作为芯材,制备了复合型微胶囊。实验结果表明,茉莉香精微胶囊的最大含油率可以达到38%,平均粒径为6～10μm,整理后的棉布具有较好的缓释性能。而且整理后的织物具有较好的透气透湿性,其透气阻值为0.29 kPa?s/m,透湿量为10828 g/( m2?24h)。复合型香精微胶囊整理的织物的透气阻值为0.282 kPa?s/m,透湿量为10870 g/( m2?24h)。
In this paper, the functional microcapsules of skin-caring and flavor were prepared using gelatin and arabic gum as the wall materials and olive oil and jasmine oil as the core materials. The microcapsules were finished into fabric by padding to obtain functional fabric. The parameters influencing the properties of microcapsules were studied in detail. The morphology was observed by optical microscope and scanning electron microscope. The particle size and distribution were tested by laser particle size analyzer. The oil content of the microcapsules was analyzed through soxhlet extraction.
First the olive oil microcapsules with the function of slow-releasing were prepared. The process parameters, such as the dosage of the cross linker, concentration of the wall materials, pH adjustment rate and the ratio between core and wall materials, were analyzed in detail. The optimal process parameters were as follow: dosage of the cross linking agent was of 3ml, the concentration of wall materials was of 3%, the pH value of coacervation was 4.0 and the ratio of core/wall material was 1:1. The a oil content of microcapsules prepared at optimal process was up to 60% and the mean particle size was 3~8μm with good surface morphology. Olive oil microcapsules prepared with the best parameters were finished on cotton fabric through padding. The effect of pre-drying temperature, curing temperature and time, solid content of finishing agent, the ratio between finishing agent and adhesive agent were investigated. Through testing the drug-loading rate of olive oil in cotton fabric, breathable and moisture permeability, the optimum parameters were as follow: pre-drying temperature was 70℃, curing temperature was 120℃and time was 1min, solid content of finishing agent was 5%, the ratio between finishing agent and adhesive agent was 1:1. The oil content of cotton fabric was 2~5% and had a good touch feeling and whiteness. Its slow-release property tested with UV spectrophotometer was also good. Breathable and moisture permeability and washing fastness were satisfied to normal needs of fabrics.
The perfume microcapsules were prepared using the jasmine oil as the core materials. Cross linking time, the ratio of core to wall, pH and the inlet temperature of spray drying were studied to get the optimum process conditions. And the optimal parameters were used to embed jasmine essence and olive oil to get mix cores microcapsules. The results showed that the maximum oil content reached 38%, the mean particle size ranged 6~10μm, the cotton fabric finished has good slow release performance. The breathe freely moisture permeability of fabric finished were good and the air resistance is 0.29 kPa?s/m, the moisture permeability content is 10828g/(m2?24h). The air resistance of complex microcapsules is 0.282 kPa?s/m, its moisture permeability content is 10870 g/(m2?24h).
引文
[1]蔡涛,王丹,宋志祥等.微胶囊的制备技术及其国内应用进展[J].化学推进剂与高分子材料,2010,8(2):20-26.
[2]赵永金,吴海燕.微胶囊技术应用进展[J].兵团教育学院学报,2000,10(03):42-44.
[3]韩薇妍,赵有玺,龚平.微胶囊结构与性能的研究进展[J].中国生物工程杂志,2010,30(1):104-110.
[4]张继稳,钟大放,毕殿洲.释放分割法体外评价释放特征符合Higuchi方程的缓释制剂药物动力学[J].沈阳药科大学学报,2001,18(5):324-326.
[5]宋键,陈磊,李效军.微胶囊化技术及应用[M].化学工业出版社,2001:56-62.
[6]赖茂柏,孙蓉,吴晓琳.界面聚合法包覆石蜡制备微胶囊复合相变材料[J].材料导报:研究篇,2009,23(11):62-79.
[7]王少飞.微胶囊合成工艺研究综述[J].应用科技,2009,16:229-231.
[8]郭虹,翟玉春等.复凝聚法辣椒油树脂微胶囊的制备[J].分子科学学报,2006,22(04): 243-246.
[9]吴绍明,柴丽琴,邵建中.单凝聚制备护肤保健微胶囊[J].浙江理工大学学报, 2008,25(01):15-18.
[10]董志俭.复合凝聚薄荷油微胶囊的研究[D].无锡:江南大学,2008:3.
[11]谢艳丽,蒋敏,陈鸿雁.复凝聚法制备明胶/阿拉伯胶含油微胶囊工艺过程的研究[J].化学世界,2010,(1):33-38.
[12]董志俭,沈煜等.复合凝聚球状多核薄荷油微胶囊的壁材选择及固化研究[J].食品与发酵工业,2009,35:40-44.
[13]王全杰,朱先义等.艾蒿油微胶囊的研制[J].中国皮革,2007,36(23):4-7.
[14]李瑾,郑明学等.影响复凝聚法制备明胶缓释微囊的因素探讨[J].中国畜牧兽医,2009,36(6):207-209.
[15]王承南等.油茶籽油微胶囊凝聚法工艺技术的研究[J].中南林学院学报,2001,21(4):28-31.
[16]徐丽琴等.月见草油微胶囊技术的研究[J].辽宁师范大学学报自然科学版,2005,28(4):470-473.
[17]李柱来等,壳聚糖-阿拉伯胶布洛芬缓释微囊制备工艺研究[J].天然产物研究与开发,2005,17(1):51-54.
[18]陈亚泉.辣椒油的微胶囊化研究[D].长沙:湖南农业大学,2009:6.
[19]程侣柏.化工百科全书[M].北京:化学工业出版社,1994:28-31.
[20]蔡涛等.微胶囊的制备技术及其应用[J].化工中间体,2009,12:6-12.
[21]冯文昭等.新型热敏变色材料的微胶囊化研究[J].天津工业大学学报,2008,27(2):32-35.
[22]涂赞润,任宏图.光敏变色微胶囊的合成及其在纺织品中的应用[J].印染,1999,(10):5-8.
[23]李刚强等.光敏微胶囊的制备及缓释性能研究[A].中国感光学会2008非银盐影像技术及材料发展与应用学术研讨会论文集[C].北京:中国感光学会,2008:37-40.
[24]李芝等.啶虫脒与羧甲基壳聚糖和阿拉伯胶缓释微胶囊的制备及性能研究[J].化学研究与应用,2010,22(6):745-748.
[25]马艳等.新型喜树碱缓释微胶囊的制备[J].哈尔滨工业大学学报,2009,41(4):48-50.
[26]张艳等.缓释型香精微胶囊的制备及应用[J].日用化学工业,2007,37(1):31-33.
[27]王奎涛等.玫瑰香精微胶囊缓释性的影响因素研究[J].日用化学工业,2005,35(6):368-370.
[28]宋键.微胶囊化技术及应用[M].北京:化学工业出版社,2001.
[29] Chao Y W,Wei H Y,Yin Z,eta. Fabrication of drug-loaded biodegradable microcapsules for controlled release by combination of solvent evaporation and layer-by-layer self-assembly[J]. International Journal of Pharmaceutics, 2007, 331(1): 132-145.
[30]莫名月,李国明,孔志玲.壳聚糖负载利福平微囊的制备及其性能研究[J].华南师范大学学报(自然科学版),2006,4:87-91.
[31] Qinghe Z, Bingyun L. pH-controlled drug loading and release from biodegradable microcapsules[J]. Nano medicine: Nano technology, Biology, Biology and Medicine, 2008, xx: 1-9.
[32]丘晓琳,李国明,叶俊生.低分子肝素/壳聚糖/海藻酸钠复合微囊的制备及释药性能[J].应用化学, 2005,22(4):361-366.
[33] Deladinol, Anbinderps,Albasn, et al1. Encapsulation of natural anti oxidants extracted from Ilex paraguariensis[J]. Carbohydrate Polymers, 2008, 71:126-1341.
[34]刘成圣,胡莉,范冰等.壳聚糖食品微胶囊的制备及其控制释放[J].食品工业科技,2002,2:334-341.
[35]王潮霞,陈水林.芳香疗法及其在纺织品上的应用[J].印染,2001(8):40-42.
[36] Atanne M, Murieluriel J, Stephane D, et al. Flavour en-capsulation and controlled release-a review[J]. Interna-tional Journal of Food Science and Technolog, 2006, 41:1-21 .
[37]焦利勇,王晓敏,白莹.柠檬油香精微胶囊的制备及影响因素研究[J].包装技术与工程,2010,31(7):1-14.
[38]赵新.微胶囊香味油墨及其在印刷中的应用[J].设备与器材,2001(1):38-39.
[39]郭俊华,段秀珍.洗衣粉中茉莉香精微胶囊的制备条件与研究[J].香料香精化妆品,2010(2):26-28.
[40]于海艳.香精微胶囊制备技术新进展及其发展趋势分析[J].食品与发酵工业,2007,33(2):108-113.
[41]韩笑.香味微胶囊的制备和应用实践[J].染整技术,2006,28(9):34-36.
[42]钟昌勇.橄榄油化学组成及应用综述[J].林产化工通讯,2005,39(6):34-38.
[43]李少华,阮海健.橄榄油的加工技术与开发利用研究[J].粮油加工与食品机械,2006,5:45-50.
[44] Gracia Patricia Blanch, Gema Flores, Maria del Mar Caja, Maria Luisa Ruiz del Castillo. Jasminum polyanthum Franch. as a Natural Source of (-)-Methyl Jasmonate: an Alternative to the Use of the Synthetic Standard[J]. Phytochem. Anal, 2009,20: 427-433.
[45] Hiromasa Kiyota, Emi Higashi, Takanori Koike, Takayuki Oritani. Syntheses and odour descriptions of jasmine lactone and cis-jasmone analogues bearing cyclopropane moieties[J]. Flavour and fragrance journal, 2001,16:175-179.
[46]杭伟明.涤纶和锦纶织物的抗静电整理[J].纺织学报,2009,30(6):86-89.
[47]曹万里,顾志安.涤纶及其混纺织物的抗起毛起球整理[J].印染,2004(7):31-32.
[48]张永波,高来宝,曹虹霞.芳香整理用聚氨酯微胶囊的研制[J].纺织学报,2008,24(6):517-519.
[49] Gouin S, Microencapsulation:industrial appraisal of existing technologies and trends[J]. Trends in food science & technology, 2004,15:330-347.
[50] Su R, Su JX, Wang K, Chen DQ. Phase behavior and properties of polyvinyl alcohol/gelatin blends with novel pH-dependence[J]. Journal of Polymer Science: Polymer Physics, 2009,47:239-247.
[51] YU Danfeng, PEI Guangling. Preparation and properties of olive oil microcapsules[C]. Textile Bioengineering and lnformatics Symposium Proceedings, Beijing, 2011:314-320.
[52] Lina Zhang,Yong Jin,Hai-qing Liu,Yu-ming Du. Structure and Control Release of Chitosan/Carboxymethyl Cellulose Microcapsules[J]. Journal of Applied Polymer Science, 2001,82:584-592.
[53] Yonghai Li,Zaisheng Cai. Microencapsulation and Application of Fluorine-Free Water Repellent Agent-AH102[J]. Journal of Applied Polymer Science, 2011,119,330-335.
[54] S ennur Alay,Fethiye G?de,Cemil Alkan. Synthesis and Thermal Properties of Poly(n-butyl acrylate)/n-Hexadecane Microcapsules Using Different Cross-Linkers and Their Application to Textile Fabrics[J]. Journal of Applied Polymer Science, 2011,120,2821-2829.
[55] Ian Holme. Innovative technologies for high performance textiles[J]. Society of Dyers and Colourists, Color. Technol. 2007,123,59-73.
[56] Allen G. Li,Matthew J. Quinn,Yasmin Siddiqui,Michael D. Wood,Isaac F. Federiuk,Heather M. Duman,W. Kenneth Ward. Elevation of transforming growth factor beta (TGFb) and its downstream mediators in subcutaneous foreign body capsule tissue[J]. Increased TGFb in foreign body encapsulation, 2007,82A:498-508.
[57] Swapan Kumar Ghosh, Marc Van Parys. Functional Coatings: by Polymer Microencapsulation[M]. Version 6. Zelzate : Wiley-VCH ,2006:221-258.
[58] HUANG Huajiang, XIAO Dongchen, YUAN Weikang. Microencapsulation based on emulsification for producing pharmaceutical products: a literature review[J]. Dev. Chem. Eng. Mineral Process, 2006:14(3/4), pp:515-544.
[59]王俊华,蔡再生.角鲨烷微胶囊在织物护肤整理中的应用[J].纺织学报,2010,31(1):76-80.
[60]熊葳,顾平.香味保健纺织品的开发现状与微胶囊生产技术[J].国外丝绸,2009,4:29-31.
[61] Udaya N, Wanasundara, Fereidoon Shahidi. Storage stability of microencapsulated seal blubber oil[J]. Journal of Food Lipids,2009,24(1):36-47.
[62]魏菊,王瑾,刘向.纯棉织物芳香微胶囊整理的探讨[J].染整技术,2008,30(7):30-32.
[63] Mar′?a Jos′e Moyano, Heredia, Mel′endez-Mart′?nez. The color of olive oils: Thepigments and their likely health benefits and visual and instrumental methods of analysis[J]. Comprehensive Review in Food Science and Safety,2010,9:278-291.
[64] Patricia Calvo, Teresa Hernández, Mercedes Lozano et al. Microencapsulation of extra-virgin olive oil by spray-drying: Influence of wall material and olive quality[J]. European Journal of Lipid Science and Technology, 2010,112(8):852-858.
[65] Javad Omidi, Mohammad Khorram, Abdolreza Samimi. Combined method of complex coacervation and electrospray for encapsulate preparation[J]. Journal of Applied Polymer Science,2010,117:322–328.
[66]陈文文,阎克路.纳米炭黑在羊毛织物上的应用[J].印染助剂,2007,24(6):17-23.
[67]赖军,樊丽辉,赵瑞佳,沈德权,杨文堂.有机硅改性聚氨酯抗皱整理剂的制备与应用[J].染料与助剂,2010,32(9):29-32.
[68] Ming-Shien Yen,Kuo-Shien Huang. The study of rapid curing crease-resistant processing on cotton fabrics. Part I. The effect of chitosan on the physical properties of processed fabrics[J]. Journal of Applied Polymer Science, 2000,78(1):35-40.
[69] Martin Ferus Comelo. Control of dyeing processes by colour measurement[J]. Review of Progress in Coloration and Related Topics, 2002,32(1):1-12.
[70]李维贤,赵耀明.乙二醛型抗皱整理剂在真丝织物上的应用[J].印染助剂,2000,17(4):19-22.
[71]崔莉,范雪荣,李艳娟,陈坚.微生物谷氨酰胺转胺酶改善羊毛织物性能[J].纺织学报, 2006,27(8):7-11.
[72] Wang QJ, Zhu XY, Lai YW. Study of artemisia oil microcapsule additives. China Leather 2007;36:4-7.
[73]郭明勋,于玲编.明胶微胶囊化技术[J].明胶科学与技术,2000,20(3):113-122.
[74] Atmane Madene, Muriel Jacquot, Jo?l Scher, Stéphane Desobry. Flavour encapsulation and controlled release–a review[J]. International Journal of Food Science and Technology, 2006,41:1-21.
[75] Bing Wang, Jiasen Zhao. Studies on Preparation of Immersion-Type Polypropylene Fragrant Fiber. I. Formation of Matrix Fiber in the Melt-Spinning Process and Its Technique of Immersion Essential Oil[J]. Journal of Applied Polymer Science, 2003,90:1970-1979.
[76] ]F. Mathieu, S. Ugazio, G. Carnelle,Y. Ducin, J. Legrand, Complex Coacervation of theGelatin–Poly(acrylic acid) System[J], Wiley InterScience, 2006,101:708-714.
[77]麻成金,马美湖,张永康,姚茂君.喷雾干燥法制备微胶囊化杜仲籽油的研究[J].中国粮油学报,2008,23(6):141-144.
[78]胡婷婷,乐园,赵宏,沈志刚,陈建峰.高压均质技术结合喷雾干燥法制备布地奈德多孔微球[J].北京化工大学学报(自然科学版),2009,36(2):9-13.
[79] Marcela M. Baracat, Adriana M. Nakagawa, Luis A. P. Freitas, Osvaldo de Freitas. Microcapsule Processing in a Spouted Bed[J]. The Canadian Journal of Chemical Engineering, 2004,82:134-141.
[80] M.E. rodriguez-huezo, R.pedroza-islas, L.A. prado-barragan, C.I. beristain, E.J. vernon-carter. Microencapsulation by Spray Drying of Multiple Emulsions Containing Carotenoids[J]. Food Engineering and Physical Properties, 2004,69(7):351-359.
[81] Hua-Jiang Huang, Xiao Dong Chen, Wei-Kang Yuan. Microencapsulation Based on Emulsification for Producing Pharmaceutical Products: A Literature Review[J]. Dev. Chem. Eng. Mineral Process, 2006,14(3/4), pp:515-544.
[82] M. Z. Lu, H. L. Lan, F. F. Wang, S. J. Chang, Y. J. Wang. Cell Encapsulation with Alginate and a-Phenoxycinnamylidene-Acetylated Poly(Allylamine)[J]. Biotecchnology and bioengneering, 2000,70,(5):479-483.
[83] Branko Ali?,Ur?ka ? ebenik, Matja? Krajnc. Differential Scanning Calorimetric Examination of Melamine–Formaldehyde Microcapsules Containing Decane[J]. Journal of Applied Polymer Science, 2011,119:3687-3695.
[84] Thomas Chandy, Daniel L. Mooradian, Gundu H.R. Rao. Evaluation of Modified Alginate-Chitosan-Polyethylene Glycol Microcapsules for Cell Encapsulation[J]. Artificial Organs, 1999,23(10):894-903.
[85] J. M. Van Raamsdonk,P. L. Chang. Osmotic pressure test: A simple, quantitative method to assess the mechanical stability of alginate microcapsules[J]. Mechanical atability of microcapsules, 2001,54: 264-271.
[86] C. K. YEOM,S. B. OH,J. W. RHIM,J. M. LEE. Microencapsulation of Water-Soluble Herbicide by Interfacial Reaction. I. Characterization of Microencapsulation[J]. Journal of Applied Polymer Science, 2000,78:1645-1655
[87]王奎涛,葛艳蕊,冯薇,袁中凯.玫瑰香精微胶囊缓释性的影响因素研究[J].日用化学工业, 2005,35(6):368-370.
[88] J. Wikstr?m,H. Syv?j?rviA. UrttiM. Yliperttula, Kinetic simulation model of protein secretion and accumulation in the cell microcapsules[J]. The journal of genemedicine, 2008,10:575-582.
[89] Andy Leung, Matt Trau, Lars Keld Nielsen. Assembly of multilayer PSS/PAH membrane on coherent alginate/PLO microcapsule for long-term graft transplantation[J]. Multilayer PSS/PAH membrane for long-term graft transplantation, 2009,88A: 226-237.
[90] Bing Han,Xiaoyan Wang,Xuejun Gao,Jiguang Liu,Fuxin Liang,Xiaozhong Qu,Zhenzhong Yang. Synthesis and characterization of biodegradable microcapsules for the controlled delivery of calcium hydroxide[J]. Original research report, 2011,99B:120-126.
[91] I. Tarak??o?lu,A. Cay. Experimental study of a new shock pre-drying method for cotton fabrics[J]. International journal of enegy research, 2007,31:886-894.
[92] Pibo Ma, Xin Wang, Weilin Xu,Genyang Cao. Application of corona discharge on desizing of polyvinyl alcohol on cotton fabrics[J]. Journal of Applied Polymer Science,2009,114(5),:2887-2892.
[93]李国萍,孙卫国,谢焕.温度对羊毛溶液整理棉织物性能的影响[J].纺织科技进展,2011,4:50-51.
[94]张辉,范立红,谢光银.壳聚糖整理棉织物透湿和抗折皱性能研究[J].纺织高校基础科学学报, 2009,22(1):113-117.
[95]沈细周,吴佳林,曾翠霞,郑少琼.针织面料的水性PU整理工艺及其性能研究[J].化纤与纺织技术, 2009,2:1-4.
[96]杨子明,李鹂,欧韦文,钟慧仪,汪国成.微胶囊化学交联法对棉织物的功能整理[J].高分子材料科学与工程,2010,26(7):118-121.
[2]赵永金,吴海燕.微胶囊技术应用进展[J].兵团教育学院学报,2000,10(03):42-44.
[3]韩薇妍,赵有玺,龚平.微胶囊结构与性能的研究进展[J].中国生物工程杂志,2010,30(1):104-110.
[4]张继稳,钟大放,毕殿洲.释放分割法体外评价释放特征符合Higuchi方程的缓释制剂药物动力学[J].沈阳药科大学学报,2001,18(5):324-326.
[5]宋键,陈磊,李效军.微胶囊化技术及应用[M].化学工业出版社,2001:56-62.
[6]赖茂柏,孙蓉,吴晓琳.界面聚合法包覆石蜡制备微胶囊复合相变材料[J].材料导报:研究篇,2009,23(11):62-79.
[7]王少飞.微胶囊合成工艺研究综述[J].应用科技,2009,16:229-231.
[8]郭虹,翟玉春等.复凝聚法辣椒油树脂微胶囊的制备[J].分子科学学报,2006,22(04): 243-246.
[9]吴绍明,柴丽琴,邵建中.单凝聚制备护肤保健微胶囊[J].浙江理工大学学报, 2008,25(01):15-18.
[10]董志俭.复合凝聚薄荷油微胶囊的研究[D].无锡:江南大学,2008:3.
[11]谢艳丽,蒋敏,陈鸿雁.复凝聚法制备明胶/阿拉伯胶含油微胶囊工艺过程的研究[J].化学世界,2010,(1):33-38.
[12]董志俭,沈煜等.复合凝聚球状多核薄荷油微胶囊的壁材选择及固化研究[J].食品与发酵工业,2009,35:40-44.
[13]王全杰,朱先义等.艾蒿油微胶囊的研制[J].中国皮革,2007,36(23):4-7.
[14]李瑾,郑明学等.影响复凝聚法制备明胶缓释微囊的因素探讨[J].中国畜牧兽医,2009,36(6):207-209.
[15]王承南等.油茶籽油微胶囊凝聚法工艺技术的研究[J].中南林学院学报,2001,21(4):28-31.
[16]徐丽琴等.月见草油微胶囊技术的研究[J].辽宁师范大学学报自然科学版,2005,28(4):470-473.
[17]李柱来等,壳聚糖-阿拉伯胶布洛芬缓释微囊制备工艺研究[J].天然产物研究与开发,2005,17(1):51-54.
[18]陈亚泉.辣椒油的微胶囊化研究[D].长沙:湖南农业大学,2009:6.
[19]程侣柏.化工百科全书[M].北京:化学工业出版社,1994:28-31.
[20]蔡涛等.微胶囊的制备技术及其应用[J].化工中间体,2009,12:6-12.
[21]冯文昭等.新型热敏变色材料的微胶囊化研究[J].天津工业大学学报,2008,27(2):32-35.
[22]涂赞润,任宏图.光敏变色微胶囊的合成及其在纺织品中的应用[J].印染,1999,(10):5-8.
[23]李刚强等.光敏微胶囊的制备及缓释性能研究[A].中国感光学会2008非银盐影像技术及材料发展与应用学术研讨会论文集[C].北京:中国感光学会,2008:37-40.
[24]李芝等.啶虫脒与羧甲基壳聚糖和阿拉伯胶缓释微胶囊的制备及性能研究[J].化学研究与应用,2010,22(6):745-748.
[25]马艳等.新型喜树碱缓释微胶囊的制备[J].哈尔滨工业大学学报,2009,41(4):48-50.
[26]张艳等.缓释型香精微胶囊的制备及应用[J].日用化学工业,2007,37(1):31-33.
[27]王奎涛等.玫瑰香精微胶囊缓释性的影响因素研究[J].日用化学工业,2005,35(6):368-370.
[28]宋键.微胶囊化技术及应用[M].北京:化学工业出版社,2001.
[29] Chao Y W,Wei H Y,Yin Z,eta. Fabrication of drug-loaded biodegradable microcapsules for controlled release by combination of solvent evaporation and layer-by-layer self-assembly[J]. International Journal of Pharmaceutics, 2007, 331(1): 132-145.
[30]莫名月,李国明,孔志玲.壳聚糖负载利福平微囊的制备及其性能研究[J].华南师范大学学报(自然科学版),2006,4:87-91.
[31] Qinghe Z, Bingyun L. pH-controlled drug loading and release from biodegradable microcapsules[J]. Nano medicine: Nano technology, Biology, Biology and Medicine, 2008, xx: 1-9.
[32]丘晓琳,李国明,叶俊生.低分子肝素/壳聚糖/海藻酸钠复合微囊的制备及释药性能[J].应用化学, 2005,22(4):361-366.
[33] Deladinol, Anbinderps,Albasn, et al1. Encapsulation of natural anti oxidants extracted from Ilex paraguariensis[J]. Carbohydrate Polymers, 2008, 71:126-1341.
[34]刘成圣,胡莉,范冰等.壳聚糖食品微胶囊的制备及其控制释放[J].食品工业科技,2002,2:334-341.
[35]王潮霞,陈水林.芳香疗法及其在纺织品上的应用[J].印染,2001(8):40-42.
[36] Atanne M, Murieluriel J, Stephane D, et al. Flavour en-capsulation and controlled release-a review[J]. Interna-tional Journal of Food Science and Technolog, 2006, 41:1-21 .
[37]焦利勇,王晓敏,白莹.柠檬油香精微胶囊的制备及影响因素研究[J].包装技术与工程,2010,31(7):1-14.
[38]赵新.微胶囊香味油墨及其在印刷中的应用[J].设备与器材,2001(1):38-39.
[39]郭俊华,段秀珍.洗衣粉中茉莉香精微胶囊的制备条件与研究[J].香料香精化妆品,2010(2):26-28.
[40]于海艳.香精微胶囊制备技术新进展及其发展趋势分析[J].食品与发酵工业,2007,33(2):108-113.
[41]韩笑.香味微胶囊的制备和应用实践[J].染整技术,2006,28(9):34-36.
[42]钟昌勇.橄榄油化学组成及应用综述[J].林产化工通讯,2005,39(6):34-38.
[43]李少华,阮海健.橄榄油的加工技术与开发利用研究[J].粮油加工与食品机械,2006,5:45-50.
[44] Gracia Patricia Blanch, Gema Flores, Maria del Mar Caja, Maria Luisa Ruiz del Castillo. Jasminum polyanthum Franch. as a Natural Source of (-)-Methyl Jasmonate: an Alternative to the Use of the Synthetic Standard[J]. Phytochem. Anal, 2009,20: 427-433.
[45] Hiromasa Kiyota, Emi Higashi, Takanori Koike, Takayuki Oritani. Syntheses and odour descriptions of jasmine lactone and cis-jasmone analogues bearing cyclopropane moieties[J]. Flavour and fragrance journal, 2001,16:175-179.
[46]杭伟明.涤纶和锦纶织物的抗静电整理[J].纺织学报,2009,30(6):86-89.
[47]曹万里,顾志安.涤纶及其混纺织物的抗起毛起球整理[J].印染,2004(7):31-32.
[48]张永波,高来宝,曹虹霞.芳香整理用聚氨酯微胶囊的研制[J].纺织学报,2008,24(6):517-519.
[49] Gouin S, Microencapsulation:industrial appraisal of existing technologies and trends[J]. Trends in food science & technology, 2004,15:330-347.
[50] Su R, Su JX, Wang K, Chen DQ. Phase behavior and properties of polyvinyl alcohol/gelatin blends with novel pH-dependence[J]. Journal of Polymer Science: Polymer Physics, 2009,47:239-247.
[51] YU Danfeng, PEI Guangling. Preparation and properties of olive oil microcapsules[C]. Textile Bioengineering and lnformatics Symposium Proceedings, Beijing, 2011:314-320.
[52] Lina Zhang,Yong Jin,Hai-qing Liu,Yu-ming Du. Structure and Control Release of Chitosan/Carboxymethyl Cellulose Microcapsules[J]. Journal of Applied Polymer Science, 2001,82:584-592.
[53] Yonghai Li,Zaisheng Cai. Microencapsulation and Application of Fluorine-Free Water Repellent Agent-AH102[J]. Journal of Applied Polymer Science, 2011,119,330-335.
[54] S ennur Alay,Fethiye G?de,Cemil Alkan. Synthesis and Thermal Properties of Poly(n-butyl acrylate)/n-Hexadecane Microcapsules Using Different Cross-Linkers and Their Application to Textile Fabrics[J]. Journal of Applied Polymer Science, 2011,120,2821-2829.
[55] Ian Holme. Innovative technologies for high performance textiles[J]. Society of Dyers and Colourists, Color. Technol. 2007,123,59-73.
[56] Allen G. Li,Matthew J. Quinn,Yasmin Siddiqui,Michael D. Wood,Isaac F. Federiuk,Heather M. Duman,W. Kenneth Ward. Elevation of transforming growth factor beta (TGFb) and its downstream mediators in subcutaneous foreign body capsule tissue[J]. Increased TGFb in foreign body encapsulation, 2007,82A:498-508.
[57] Swapan Kumar Ghosh, Marc Van Parys. Functional Coatings: by Polymer Microencapsulation[M]. Version 6. Zelzate : Wiley-VCH ,2006:221-258.
[58] HUANG Huajiang, XIAO Dongchen, YUAN Weikang. Microencapsulation based on emulsification for producing pharmaceutical products: a literature review[J]. Dev. Chem. Eng. Mineral Process, 2006:14(3/4), pp:515-544.
[59]王俊华,蔡再生.角鲨烷微胶囊在织物护肤整理中的应用[J].纺织学报,2010,31(1):76-80.
[60]熊葳,顾平.香味保健纺织品的开发现状与微胶囊生产技术[J].国外丝绸,2009,4:29-31.
[61] Udaya N, Wanasundara, Fereidoon Shahidi. Storage stability of microencapsulated seal blubber oil[J]. Journal of Food Lipids,2009,24(1):36-47.
[62]魏菊,王瑾,刘向.纯棉织物芳香微胶囊整理的探讨[J].染整技术,2008,30(7):30-32.
[63] Mar′?a Jos′e Moyano, Heredia, Mel′endez-Mart′?nez. The color of olive oils: Thepigments and their likely health benefits and visual and instrumental methods of analysis[J]. Comprehensive Review in Food Science and Safety,2010,9:278-291.
[64] Patricia Calvo, Teresa Hernández, Mercedes Lozano et al. Microencapsulation of extra-virgin olive oil by spray-drying: Influence of wall material and olive quality[J]. European Journal of Lipid Science and Technology, 2010,112(8):852-858.
[65] Javad Omidi, Mohammad Khorram, Abdolreza Samimi. Combined method of complex coacervation and electrospray for encapsulate preparation[J]. Journal of Applied Polymer Science,2010,117:322–328.
[66]陈文文,阎克路.纳米炭黑在羊毛织物上的应用[J].印染助剂,2007,24(6):17-23.
[67]赖军,樊丽辉,赵瑞佳,沈德权,杨文堂.有机硅改性聚氨酯抗皱整理剂的制备与应用[J].染料与助剂,2010,32(9):29-32.
[68] Ming-Shien Yen,Kuo-Shien Huang. The study of rapid curing crease-resistant processing on cotton fabrics. Part I. The effect of chitosan on the physical properties of processed fabrics[J]. Journal of Applied Polymer Science, 2000,78(1):35-40.
[69] Martin Ferus Comelo. Control of dyeing processes by colour measurement[J]. Review of Progress in Coloration and Related Topics, 2002,32(1):1-12.
[70]李维贤,赵耀明.乙二醛型抗皱整理剂在真丝织物上的应用[J].印染助剂,2000,17(4):19-22.
[71]崔莉,范雪荣,李艳娟,陈坚.微生物谷氨酰胺转胺酶改善羊毛织物性能[J].纺织学报, 2006,27(8):7-11.
[72] Wang QJ, Zhu XY, Lai YW. Study of artemisia oil microcapsule additives. China Leather 2007;36:4-7.
[73]郭明勋,于玲编.明胶微胶囊化技术[J].明胶科学与技术,2000,20(3):113-122.
[74] Atmane Madene, Muriel Jacquot, Jo?l Scher, Stéphane Desobry. Flavour encapsulation and controlled release–a review[J]. International Journal of Food Science and Technology, 2006,41:1-21.
[75] Bing Wang, Jiasen Zhao. Studies on Preparation of Immersion-Type Polypropylene Fragrant Fiber. I. Formation of Matrix Fiber in the Melt-Spinning Process and Its Technique of Immersion Essential Oil[J]. Journal of Applied Polymer Science, 2003,90:1970-1979.
[76] ]F. Mathieu, S. Ugazio, G. Carnelle,Y. Ducin, J. Legrand, Complex Coacervation of theGelatin–Poly(acrylic acid) System[J], Wiley InterScience, 2006,101:708-714.
[77]麻成金,马美湖,张永康,姚茂君.喷雾干燥法制备微胶囊化杜仲籽油的研究[J].中国粮油学报,2008,23(6):141-144.
[78]胡婷婷,乐园,赵宏,沈志刚,陈建峰.高压均质技术结合喷雾干燥法制备布地奈德多孔微球[J].北京化工大学学报(自然科学版),2009,36(2):9-13.
[79] Marcela M. Baracat, Adriana M. Nakagawa, Luis A. P. Freitas, Osvaldo de Freitas. Microcapsule Processing in a Spouted Bed[J]. The Canadian Journal of Chemical Engineering, 2004,82:134-141.
[80] M.E. rodriguez-huezo, R.pedroza-islas, L.A. prado-barragan, C.I. beristain, E.J. vernon-carter. Microencapsulation by Spray Drying of Multiple Emulsions Containing Carotenoids[J]. Food Engineering and Physical Properties, 2004,69(7):351-359.
[81] Hua-Jiang Huang, Xiao Dong Chen, Wei-Kang Yuan. Microencapsulation Based on Emulsification for Producing Pharmaceutical Products: A Literature Review[J]. Dev. Chem. Eng. Mineral Process, 2006,14(3/4), pp:515-544.
[82] M. Z. Lu, H. L. Lan, F. F. Wang, S. J. Chang, Y. J. Wang. Cell Encapsulation with Alginate and a-Phenoxycinnamylidene-Acetylated Poly(Allylamine)[J]. Biotecchnology and bioengneering, 2000,70,(5):479-483.
[83] Branko Ali?,Ur?ka ? ebenik, Matja? Krajnc. Differential Scanning Calorimetric Examination of Melamine–Formaldehyde Microcapsules Containing Decane[J]. Journal of Applied Polymer Science, 2011,119:3687-3695.
[84] Thomas Chandy, Daniel L. Mooradian, Gundu H.R. Rao. Evaluation of Modified Alginate-Chitosan-Polyethylene Glycol Microcapsules for Cell Encapsulation[J]. Artificial Organs, 1999,23(10):894-903.
[85] J. M. Van Raamsdonk,P. L. Chang. Osmotic pressure test: A simple, quantitative method to assess the mechanical stability of alginate microcapsules[J]. Mechanical atability of microcapsules, 2001,54: 264-271.
[86] C. K. YEOM,S. B. OH,J. W. RHIM,J. M. LEE. Microencapsulation of Water-Soluble Herbicide by Interfacial Reaction. I. Characterization of Microencapsulation[J]. Journal of Applied Polymer Science, 2000,78:1645-1655
[87]王奎涛,葛艳蕊,冯薇,袁中凯.玫瑰香精微胶囊缓释性的影响因素研究[J].日用化学工业, 2005,35(6):368-370.
[88] J. Wikstr?m,H. Syv?j?rviA. UrttiM. Yliperttula, Kinetic simulation model of protein secretion and accumulation in the cell microcapsules[J]. The journal of genemedicine, 2008,10:575-582.
[89] Andy Leung, Matt Trau, Lars Keld Nielsen. Assembly of multilayer PSS/PAH membrane on coherent alginate/PLO microcapsule for long-term graft transplantation[J]. Multilayer PSS/PAH membrane for long-term graft transplantation, 2009,88A: 226-237.
[90] Bing Han,Xiaoyan Wang,Xuejun Gao,Jiguang Liu,Fuxin Liang,Xiaozhong Qu,Zhenzhong Yang. Synthesis and characterization of biodegradable microcapsules for the controlled delivery of calcium hydroxide[J]. Original research report, 2011,99B:120-126.
[91] I. Tarak??o?lu,A. Cay. Experimental study of a new shock pre-drying method for cotton fabrics[J]. International journal of enegy research, 2007,31:886-894.
[92] Pibo Ma, Xin Wang, Weilin Xu,Genyang Cao. Application of corona discharge on desizing of polyvinyl alcohol on cotton fabrics[J]. Journal of Applied Polymer Science,2009,114(5),:2887-2892.
[93]李国萍,孙卫国,谢焕.温度对羊毛溶液整理棉织物性能的影响[J].纺织科技进展,2011,4:50-51.
[94]张辉,范立红,谢光银.壳聚糖整理棉织物透湿和抗折皱性能研究[J].纺织高校基础科学学报, 2009,22(1):113-117.
[95]沈细周,吴佳林,曾翠霞,郑少琼.针织面料的水性PU整理工艺及其性能研究[J].化纤与纺织技术, 2009,2:1-4.
[96]杨子明,李鹂,欧韦文,钟慧仪,汪国成.微胶囊化学交联法对棉织物的功能整理[J].高分子材料科学与工程,2010,26(7):118-121.