基于机械手的背俞穴阻抗检测系统
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
经络是中医基础理论的组成部分,为中华民族的健康和发展做出了巨大贡献。腧穴分布在经络上,是人体气血输注出入的地方。其中,背俞穴位于背腰部足太阳膀胱经第一侧线上,依脏腑位置而上下排列,临床上被广泛应用于诊断脏腑疾病。本文设计了一套人体背俞穴阻抗检测系统,由机械手阻抗采集装置和PC检测平台组成。通过检测人体背俞穴阻抗,分析它与人体疾病的联系,为医疗诊断提供客观的数据。本文的主要工作包括三个部分的内容:
     一、阻抗采集方案设计。在光线投射器的辅助下完成人体背俞穴的定位。然后将探测电极沿着背俞穴移动,从肺俞开始到膀胱俞结束,记录所经过穴位的阻抗数据。
     二、系统软硬件设计。搭建机械手检测平台,由三个相互垂直做平移运动的机械臂、相应的控制系统、计算机和探测电极组成,从而能够保证阻抗采集时速度、压力恒定。实现了EasySMC控制器、阻抗采集设备、步进电机及驱动器等的连接和调试。编写串口通信程序完成机械手运动控制和探测电极压力的PID控制。信号发生器产生交流激励信号,通过采集装置的转换,将人体阻抗信息通过音频LineIn接口以波形文件的格式记录下来。
     三、阻抗数据的处理和分析。对样本数据进行均值滤波,消除噪声干扰。使用希尔伯特变换、极值法和低通数字滤波提取音频阻抗数据的包络线,并通过转换得到人体阻抗的实际大小。对受试者同侧背俞穴阻抗连续多次测量,验证了系统的有效性。实验结果还表明正弦波信号的频率对测量结果影响较大,人体阻抗大小随着频率增大而减小;改变压力的大小,对测量结果影响不大。
     目前本系统已经成功应用于杭州市中医院的临床实验当中,完成数据的采集工作,为以后进一步研究背俞穴阻抗与疾病的关系打下了良好的基础,有着广阔的应用前景。
The meridian theory is an important component of the traditional Chinese Medicine, which has contributed a lot to the health and development of Chinese natron. Acupoints are located along the meridian, where Qi-blood of human body comes in and out. Among them, Back-shu points lie along the circulation route of The Bladder Meridian of Foot-Taiyang, corresponding to the position of Zang-Fu organs. The Back-shu points are widely used to diagnose Zang-Fu diseases. The Human Body Impedance Detecting System has been designed, which consists of the manipulator for data acquisition and the PC diagnosis platform. The system aims to analyze the relationship between human body impedance and diseases, through detecting the characteristics of the impedance, and to provide objective data for medical diagnosis. This thesis is divided into three parts.
     Part one: impedance acquisition design. The light projector helps to locate the Back-shu points, and then moves the detecting electrode automatically along the Back-shu points, from Feishu to Pangguangshu, recording the human body impedance at the same time.
     Part two: system design. The manipulator platform is built with three mutually perpendicular arms, the corresponding control system, PC and the detecting electrode, in order to assure the stability of velocity and pressure while capturing data. The system enables us to design and debug EasySMC control, step motor and its driver, data acquisition equipment, etc. Programs of serial port communication are written to fulfill these functions: the movement control of manipulator and PID control of electrode pressure detection. The human body impedance data is recorded through the LineIn port of the PC.
     Part three: data processing and analysis. The process includes denoising the audio impedance data by mean filter, and extracting the envelop of audio impedance data by Hilbert-Transform, extremum method and digital low-pass filter. Then the real human body impedance is calculated through transformation. The impedance of Back-shu points is detected for multiple times continuously, to validate the usability of the system. The experiment indicates that the frequency of sinusoidal signal influences the impedance a lot. When the frequency grows, the impedance will make a nonlinear decrease. The change of pressure within a range has very little influence on impedance.
     At present, the system has been applied to clinical experiment in Hangzhou Chinese Medicine Hospital. The characteristics of impedance need further study to identify its relationship with diseases, which has already shown a bright future in application.
引文
1 区结成 编.当中医遇上西医:历史与省思.北京:生活·读书·新知三联书店2006
    2 周学胜 编.中医基础理论图解表.北京:人民卫生出版社,2000
    3 胡翔龙,包景珍,马廷芳 编.中国经络现代研究.北京:人民卫生出版社,1990
    4 王本显 编译.国外对经络问题的研究.北京:人民卫生出版社,1984
    5 麻仲学 编.国际针灸交流手册.济南:山东科学技术出版社,1985
    6 刘芳,黄光英.经络的生物物理学、化学特性的研究进展.针刺研究,2007,32(4):281-284
    7 Hsin Hsiu,Shih-Min Huang,Pin-Tsun Chao etc.Study on the microcirculatory blood velocity of acupoints monitored by laser Doppler signal.Preceedings of the 29~(th)Annual International Conference of the IEEE EMBS,2007,8:959-962
    8 王文艇,钟季康,马骏.生物阻抗技术概述.上海生物医学工程,2005,26(2):119-123
    9 吴润泽,高小榕,欧阳婧.多路独立人体阻抗测量和信号分析.航天医学与医学工程,2001,14(6):429-433
    10 刘宝华.高灵敏度生物阻抗检测系统的设计.计量学报,2002,23(4):311-314
    11 黄仲曦,邓亲恺,郭云波等.一种新的六电极人体阻抗测量方法.中国医学物理学杂志,2000,17(3):189-191
    12 张珂,李剑.宽频带生物阻抗测量系统的研制.应用天地,2007,26(10):53-56
    13 K.D.Sossmeier,G.L.Callegari,L.S.Dorneles etc.Wide-range frequency method to obtain the transverse permeability from impedance measurements.Journal of Magnetism and Magnetic Materials,2008,2:e1-e3
    14 任超世.医学电阻抗技术与乳腺肿瘤检测.中国医疗器械信息,2002,8(6)
    15 史亚军 邓亲恺.人体脂肪测量新方法研究.中国医学物理学杂志,2002,19(3):188-192
    16 王祥瑞,杭燕南.电生物阻抗在重症患者监测中的应用.1992,4(4):234-236
    17 张栋,付卫星,王淑友.经脉温度特性的红外热像图显示.针刺研究,1996,21(3):63-67
    18 胡翔龙,汪培清,许金森 等.人体体表循经红外辐射轨迹的主要特征和显现规律研究.红外与毫米波学报,2001,20(5):325-328
    19 胡翔龙,许金森,叶蕾等.人体体表循经红外辐射轨迹的加热诱发.红外与毫米波学报,2002,21(1):6-11
    20 胡翔龙,许金森,王培清等.人体体表循经红外辐射轨迹形成机理的初步探讨.红外与毫米波学报,2003,22(3):175-180
    21 杨洪钦,谢树森,胡翔龙.基于红外热像技术的经络现象及其时间相关性.红外与毫米波学报,2007,26(5):340-343
    22 杜建强,欧顺云.核医学在经络领域的研究现状.中国医药信息,2007,24(2):2-4
    23 陈英茂,田嘉禾,何义杰等.体内18F-FDG循经迁移线的三维断层及透视观察.中国针灸,2002,22(9):603-605
    24 周章玲 田嘉禾,徐白萱 等.针刺慢性胆囊炎患者经穴与经外组织对胆经核素示踪影响的研究.中国针灸学会第五届全国中青年针灸推拿学术研讨会:59-63
    25 阎平,周迪湘,张鹏飞等.用32P光镜放射自显影示踪术对人体经脉循行路线组织结构的研究.解剖学杂志2002,25(2):119-121
    26 刘里远 编.古典经络学与现代经络学.北京:北京医科大学、中国协和医科大学联合出版社1997
    27 庄垂加,胡翔龙,黄聪阳 等.足太阳膀胱经循经性可阻滞性的临床研究.上海针灸杂志,2007,26(1):36-38
    28 张凡,杜书凯.循经感传激发经穴对心脏功能影响的研究进展.首都体育学院学报,2004,16(2):99-103
    29 崔承斌 王京京,吴中朝.从背俞穴与夹脊穴的关系论背俞功能带.中国针灸,2005,25(7):483-486
    30 段鲜红,郭现辉.浅谈背腰部穴位与背俞穴的不同应用.河南中医,2003,23(12):53
    31 张国强,尹百顺.浅谈腧穴命名的特点.吉林中医药,2007,27(6):59
    32 孙永平,甑薇.背俞穴位置考.北京中医药大学学报,1994,17(5):22-23
    33 杨松堤,孟凤仙.背俞穴临床应用与中医整体观.中国医学报,2000,6:47
    34 吴新贵,何源浩.背俞穴主治作用的机理探讨.中国针灸学会临床分会第十四届全国针灸学术研讨会,2006:173-175
    35 苏妆,裴景春.背俞穴研究进展.中医药学刊,2005,23(增):62-64
    36 王娟.背俞穴临床应用举隅.甘肃中医,2000,13(1):47-48
    37 周颖芳,李万瑶,赵昭和.脾俞、胃俞穴的蜂针治疗功用.蜜蜂杂志,2007,1(6):33
    38 徐斯伟.背俞穴为主治疗哮喘的疗效观察.上海针灸杂志,2007,26(10):9-10
    39 LinXue.Preliminary Investigation on Regularity of Selecting Acupoints for Treatment of Insomnia by Acupuncture.Journal of Acpuncture and Tuina Science,2005,3(1):53-56
    40 王泽涛,欧阳亮.背俞穴的临床应用.2004年全国腧穴应用与研究学术大会暨针灸教育学术研讨会,2004:92-94
    41 胡芝兰.脏腑背俞穴刍议.浙江中医学院学报,1994,18(3):47-48
    42 肖永俭,肖沛.腧穴体表面积探讨.山东中医药大学学报,1999,23(1):11-18
    43 Yilin Qin,Zhuo Cheng,Tiange Zhuang etc.Interactive Segmentation of Muscles and 3D Representation of Mefidians Based on Visible Human.Engineering in Medicine and Biology 27~(th)Annual Conferenee,Shanghai,China,2005,9:5116-5119
    44 丁立,袁修于 赵玉珍.生物皮肤传质的研究.中国工程热物理学会传热传质学学术会 议,107-112
    45 杨东 等,电气设备丛书--触/漏电保护器,化学工业出版社,2007
    46 肖贵遐,韩冰,刘国庆 等.生物电阻抗技术的医学应用.2003,20(4):287-290
    47 任超世.生物电阻抗测量技术.中国医疗器械信息,2004,10(1):21-25
    48 郭兴明,彭承琳,唐敏.生物阻抗测量系统的研究.电子技术应用,1995,11:13-15
    49 李光明,吴祈耀.生物阻抗测量技术的原理及应用.世界医疗器械,1999,5(3):51-53
    50 Javier Lario-Garcia,Ramon Pallas-Areny.Analysis of a three-component impedance using twosine waves.IEEE JMTC 2003-Instrumentation and Measurement Technology Conference,2003,3:1282-1284
    51 Ruigang Liu,Xiuzhen dong,Xuetao Shi etc.Primary Multi-frequency Data Analyze in Electrical Impedance Scanning.Engineering in Medicine and Biology 27th Annual Conference,2005:1504-1507
    52 彭承琳,郭兴明.人体细胞内外液分布阻抗测量仪的研究.仪器仪表学报,1996,17(6):612-617
    53 孙晓燕,汪涛.低频阻抗数据计算人体体液分布的可行性研究.中国生物医学工程学报,2007,26(2):188-194
    54 Takenori Fukumoto,Gwang-Moon Eom,Shigeo Ohba etc.Temporal Resolution of the Skin Impedance Measurement in Frequency-Domain Method.IEEE Transactions on Biomedical Engineering,2007,54(1):170-173
    55 J.C.Newell,D.Isaacson,D.G.Gisser.Rapid Assessment of Eletrode Characteristics for Impedance Imageing.IEEE Transactions on Biomedical Engineering,1990,37(7):735-738
    56 周学武,宋晓英,张丙忠.浅析医学电子仪器的电安全性.医疗装备,2006,19(3):36
    57 李绍炎 编著.自动机与自动线.北京:清华大学出版社,2007
    58 别洛夫 库利达 编.闻清 译.机械手.北京:原子能出版社,1982
    59 大熊繁 编.卢伯英 译.机器人控制.北京:科学出版社,2002
    60 孙金英,任明岩.步进电机的速度控制及运动规划.今日电子,2007,9:104-105
    61 李现勇 编.Visual C++串口通信技术与工程实践.北京:人民邮电出版社,2002
    62 李长林,高洁,李长林 编.Visual C++串口通信技术与典型实例.北京:清华大学出版社,2006
    63 何克忠,李伟 编.计算机控制系统.北京:清华大学出版社,2005
    64 陈雪松 杨洪耕.递归最小二乘法追踪电压闪变包络线.电力自动化设备,2006,26(6):30-32
    65 刘彬,黛桂平,林洪彬.一种改进的基于小波变换的包络提取算法研究.仪器仪表学报,2006,27(1):34-37
    66 钟佑明,金涛,秦树人.希尔伯特-黄变换钟的一种新包络线算法.数据采集与处理,2005,20(1):13-17
    67 赵学智,符红羽,陈文戈 等.小波分析在信号包络提取钟的应用.广东工业大学学报,2000,17(3):36-39
    68 Carlos Fritsch,Alberto Ibanez,Montserrat Parrilla.A Digital Envelope Detection Filter for Real-Time Operation.IEEE Transactions on Instrumentation and Measurement,1999,48(6):1287-1293
    69 Soo-Chang Pei,Min-Huang Yeh.Discrete Fractional Hilbert Transform.IEEE,1998:506-509
    70 Rashid Ansari.IIR Discrete-Time Hilbert Transformers.IEEE TRANSACTIONS ON ACOUSTICS,SPEECH,AND SIGNAL PROCESSING,1987,35(8):1116-1119
    71 Ahmed I.Zayed.Hilbert Transform Associated with the Fractional Fourier Transform.IEEE SIGNAL PROCESSING LETTERS,1998,5(8):206-208
    72 John G.Proakis,Masoud Salehi著.叶芝慧,赵新胜译.通信系统工程(第二版).北京:电子工业出版社,2002
    73 Vaclav Cizek.Discrete Hilbert Transform.IEEE Transaction on Audio and Electroacoustics,1970,18(4):340-343
    74 韩利竹 王华 编.MATLAB电子仿真与应用(第二版).北京:国防工业出版社,2003
    75 薛年喜 编.MATLAB在数字信号处理中的应用.北京:清华大学出版社,2003
    76 程佩青 编.数字信号处理教程(第二版).北京:清华大学出版社,2001
    77 丁玉美,高西全 编.数字信号处理(第二版).西安:西安电子科技大学出版社,2001
    78 Daniel P.Huttenlocher,Gregory A.Klanderman,William J.Rucklidge.Comparing Images Using the Hausdorff Distance.IEEE TRANSCATION ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE,1993,15(9):850-863
    79 郭晓新,许志闻,卢奕南等.基于Fourier-Mellin不变量的图像配准方法.仪器仪表学报,2004,25(4)421-424:
    80 卫海英 编.应用统计学.广州:暨南大学出版社,2001
    81 姜青松.对腧穴定义的质疑及思考.中国针灸,2007,27(10):791
    82 吴新贵 何源浩.背俞穴的主治作用及其机制.中国临床康复,2006,10(43):170-182

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700