骶髂关节骨折的临床解剖学数字化仿真平台的建立与应用
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
骶髂关节损伤是严重骨盆创伤中最为常见的严重损伤,随着现代交通运输、煤矿采掘、高层建筑等行业迅速发展,骶髂关节骨折在骨盆严重创伤中所占的比例亦呈现逐年上升的趋势。由于受伤原因多样且解剖位置复杂,严重的骶髂关节部位的损伤,常伴有多处严重的合并伤,如大出血,盆腔脏器的损伤等,死亡率较高。没有严重合并症的骨盆骨折,尤其是骨盆的前环骨折,既往多采用非手术的保守疗法,但患者的愈后往往因为各种不同原因而较差。但对于复杂骨盆骨折,尤其是伴随有骶髂关节损伤的骨盆后环骨折,得出的诊断则具有一定的局限性。CT技术的不断提高和更新使骨盒骨折的诊断和分型更为确切,并有助于拟定详细的早期治疗计划。但对于严重复杂的骨盆骨折,由于骨块互相重叠,X线片和二维CT扫描则很难全面客观地显示骨折和移位的程度。CT是检查明显骨盆损伤的一种重要诊断方法,特别是对于有后部复合损伤(骶髂关节损伤)的骨折效果极佳,其可检查普通X线片上显示不清楚的骨盆环后部,包括骶骨骨折,骶髂关节骨折脱位、髂骨翼及髂骨后嵴骨折等等。螺旋CT三维重建已广泛应用于临床,特别是三维重建以其立体、直观、准确的图像显示优点更为广泛地应用于骨骼系统。通过三位重建技术,采用旋转切割技术,可从各方向立体地观察骨折线,对骨折断端移位情况显示得立体直观。而且根据临床需要,可选择进行冠状位或矢状位重建,弥补二维CT每个单一体位扫描存在的不足,为骨折的诊断、分类及治疗方案的制定提供了极大的帮助。快速成型技术,简称RP或RPM技术,是80年代后期首先从美国发展起来的一门新兴制造技术,它基于材料累加概念和叠层制造方法,在计算机的控制下,根据物体的CAD模型或CT/MRI等数据,不借助其他设备,通过材料的精确堆积,制造原型的一种基于离散、堆积成型原理的新的数字化成型技术,集机械工程、CAD、激光加工、数控和新材料等技术成果于一身,可自动而迅速地将设计思想转化为物理试验模型或直接制造零件。该零件是CAD模型的物理体现,分层堆积原理的实质就是通过离散把三维制造转化为一系列二维制造叠加,是一个分解——综合的过程。将所得STL数据输入快速成型机。制作出与实体1∶1大小的模型。RP技术自动化程度高,从数字模型(CAD模型)到物理模型(原型和零件)的转化,都是计算机控制下的自动完成而无需人工干预。可制造高度复杂的零件,特别对形状复杂的人体组织器官很有用处。快速成型技术原则上可以制造出任意形状的模型。人体组织器官经CT、MRI或激光等获取图像数据输入计算机,经图形处理软件处理,重建三维模型,经快速成型系统就能制造出人体局部组织或器官的模型,并用于临床辅助诊断、复杂手术方案的确定、制作个性化的假体,也可用于医学教学。欧洲已经把医学作为快速成型技术应用的主要研究方面之一。运用RP技术,技师根据患者的CT或MRI数据体外制造出模拟患者具体情况的解剖模型,医师可以通过模型进行术前规划,指导手术。将三维重建技术与RP技术有效的结合起来,即将CT检查所获得的详尽患者病情资料,经过有效的转换为STL格式的文件,在计算机的控制下,不借助其他设备,通过材料的精确堆积,迅速的制造出仿真的创伤模型。术者可以根据骶髂关节损伤模型明确损伤的类型。根据模型所反映的情况选择最佳的手术方式、入路以及内固定器材,根据其制定治疗方法(手术或非手术)、选择手术入路切口,并在模型上模拟合适的内固定类型和安装方法(预弯钢板、
Pelvic fracture is a common serious damage in trauma. Along with rapid development of modern transportation, coal mine excavation, high-rise construction, the proportion of fracture of articulatio sacroiliaca in the serious damage also rise year by year. Because of the diversity of injured reasons and complex anatomical position, the serious damage of articulatio sacroiliaca, often is accompanied by many serious associated injuries, for example, the massive hemorrhage, the pelvic cavity internal organs damage and so on, and the mortality rate is high. Pelvic fracture without serious complications, in particular fracture of pelvic front ring, formerly be treated with the non-surgery conservative treatments, but which always has a bad outcome because of different reasons. Diagnoses about complicated pelvic fracture especially sacroiliac joint damage accompanied is local. Development of CT made the precisely diagnoses and intimate treatment plan possible. CT has become a important diagnoses method in the complicated pelvic fracture. Spiral volumetric CT three-dimensional reconstruction has been applicated in clinic. Circuitation cutting technique in Spiral volumetric CT can observe the fracture three-dimensional. It is important in the diagnoses of pelvic fracture. Rapid prototyping (RP) is a new technic developed in American during later period of 1980's. RP can manufacture the prototype ofobject by CAD models or CT/MRI date controlled by compute. RP technic comprise Machinery mechanic, CAD, laser processing and numerical control technic, can manufacture experiment models rapidly and automated. RP is a process of demix and general, controlled by compute. It is useful in manufacture complex human organ. Rapid prototyping can manufacture any type organ models controlled by computer, and applicated in clinical diagnoses and education. Clinic is the major area of RP application in Europe. Doctor can make plan of operation according three-dimensional view and RP technic. Accurate models can guide the operation method and choice of internal fixation device. Prognosis can be identify. Long-term manufacture and expensive spend are the important problem of RP technic hinder its clinical application. Another problem is the radiating spokes suffered by doctor and patient in the process of CT guide. The model can be used once. Analogue technic based on simulate principle, information technology(IT) and system technic etc. It's a technic about describe and a method about quantitative analysis. Doctor make operation decision according to the results of quantitative analysis by computer simulation. Analogue technics can solve a lot of problems in engineering and technology. The direction and plan of engineering can be checked by analogue technics. We can modify our plan if it doesn't satisfy the expectant requests in time. Analogue technics can be used in many process includes choice of assembly and design of the system or engineering. Doctor can modify the accurate models of the fracture of patients according CT or MRI view by computer simulation. It is the base of diagnosis and treatment. The recent viewpoint believed that, regarding the unstable pelvic fracture, the conservative treatment was difficult to get a precise reposition. For restoring the health, reducing the mortality rate and disabled rate, the majority scholars and clinician advocated surgical treatments. Because of the complex structure of pelvis, the explicit phantom study examination, in front of the accurate diagnosis and the technique surgery simulation, has the important value in diagnosis and treatment on fracture of articulatio sacroiliaca. This research discusses the diagnosis and treatment of fracture of articulatio sacroiliaca, on the basis of successful establishment of clinical anatomy digitization simulation model platform for individual articulatio sacroiliaca fracture.
     First part: Establishment of clinical anatomy digitization simulation model platform for individual articulatio sacroiliaca fracture and related research.Objective.1. establishment of digitized simulation model platform for individual articulatio sacroiliaca fracture.2. Carrying on the analysis using the digitized simulation platform for individual cases data: evaluation of different diagnosis methods for articulatio sacroiliaca fracture, as well as the individual clinical operative design before the operation; providing the useful informations for the clinical diagnosis and treatment. Methods: 15 cases of preservative adult pelvis specimens, 160~179 cm height, 32~78 year old, average 50 years old, no osseous pathological changes such as abnormalities, tumor and fracture. All pelvis specimens were performed X-ray and CT examination, as well as image reconstruction after scanning. The digitized simulation modeling of data was completed, and the comparison was performed between diagnose accordance rates of different diagnosis methods. Results: According to the establishment of individual digitized simulation model platform, difference of diagnose accordance rates between different diagnosis methods can be well evaluated; and the preoperative simulation can be carried out according to different data on the computer, to formulate more reasonable operative treatment plan.
     Second part: Clinical anatomical verification of digitized simulation model platform for individual articulatio sacroiliaca fracture and the simulated effect of operation on corpse specimen. Objective: comparison of effects of operative simulation with digitized simulation model platform for individual articulatio sacroiliaca fracture and with corpse specimen, and comparison of effects of guiding clinical practice. Methods: 1. operative simulation for articulatio sacroiliaca fracture on preservative adult pelvis specimens; 2. operative simulation on digitized simulation model platform for individual articulatio sacroiliaca fracture, hypothesized stimulated operative model same as the real situation of individual data; 3. performing the comparison between two; Results: the use of digitized simulation model platform for individual articulatio sacroiliaca fracture on preoperative diagnosis and operative simulation, can obtain the satisfactory effect. Conclusions: 1. The establishment of clinical anatomy digitized simulation model platform for individual articulatio sacroiliaca fracture, may have a good use on the diagnosis and operative simulation for different state of injury simulated models; 2. digitized simulation model platform for individual articulatio sacroiliaca fracture can stimulate the injury state of articulatio sacroiliaca accurately and assists to formulate the operative treatment plan, which is satisfied on the confirmation effect, and can provide exhaustive reference for the clinical treatments.
引文
1.Tile M.Pelvic ring fractures:should they be fixed?.J Bone Joint Surg,1988,70(1):1-12
    2.Burgess AR,Faxtridge BJ,Young WR.Pelvic ring disruptions:Effective classification system and treatment protocols.J Trauma,1990,151:22-30
    3.Rafat A,Wright MJ.Current management of pelvic fractures.South Med J,2000,93(8):760
    4.S Terry Canale 主编,卢世璧主译.坎贝尔骨科手术学(第9版),第三卷.山东:科学技术出版社,2001.2199-2204
    5.Routt ML Jr,Nork SE,Mills WJ.High-energy pelvic ring disruptions.Orthop Clin North Am,2002,33(1):59-72
    6.周志道,胡三保,唐子华.骨盆骨折60例报告.骨与关节损伤杂志,1999,14(6):397-398
    7.Pohlemann T.Pelvic ring injuries:assessment and concepts of surgical management.In:Ruedi TP,Murphy WM.eds.AO Principles of Fracture Manangemento lst ed.Stuttgart:Thieme,2000.391-413
    8.Pennal GF,Tile M,Waddell JP,Garside H.Pelvic disruption:assessment and classification.Clin Orthop,1980,151:12-21
    9.Bucholz RW.The pathological anatomy of Malgaigne fracture-dislocations of the pelvis.J Bone Joint Surg,1981,63(A):400
    10.Young JWR,Burgess AR.Radiologic management of pelvic ring fractures:systemic radiographic diagnosis.Baltimore,1987,Urban &Schwarzenberg
    11.Gill K,Bucholz RW.The role of computerized tomographic scanning in the evaluation of major pelvic fractures.J Bone Joint Surg Am,1984, 66(1):34-39
    
    12.马梦昆,李伟强,陈鸿.骨盆骨折CT扫描的临床价值.临床骨科杂志,1999,2(1):27-28
    13.Soubrier M,Dubost J,Boisgard S.Insufficiency fracture.A survey of 60 cases and review of the literature.Joint Bone Spine,2003,70(3):209-18
    14.梁国穗,周谋望.髋臼及骨盆骨折.中国创伤骨科杂志,2000,2(1):51-53
    15.Bucholz RW,Peter P.Assessment of pelvic stability.AAOS Inst Course Lect,1988(37):119
    16.张旭辉.骨盆骨折的诊疗进展.中国矫形外科杂志,2002,9(2):178-180
    17.Herman GT,Lin HK.Three-dimensional display of human organs from computed tomograms.Comput Graph Proc,1979,9:1-12
    18.Hemmy DC,Zonneveld FW.A decade of clinical three-dimensional imaging.Invest Radio,1994,29:489-496
    19.张晓宏,巫北海.螺旋CT与电子束CT简介.重庆医学,1998,27(2):93-94
    20.熊传芝,郝敬明,胡春艾.螺旋CT三维及四维在关节内骨折中的应用.中华骨科杂志,1999,19(11):665-668
    21.张峻,侯筱魁,王以友.三维CT重建在胫骨平台骨折中的应用.中华骨科杂志,1998,18:387-390
    22.周志勤,陈晓玲,孙泓泓.螺旋CT 3D及4D成像技术在骨盆骨折中的应用价值.中华临床杂志,2002,2(4):3-5
    23.Donna M,Elliot KF,RN.Acetabular and pelvic fractures in the pediatric patent:value of two- and three-dimensional image.Journal of pediatric Orthopaedics,1992,12:621
    24.Douglas DR,Charles J.S,Brandon WC.Depiction of pelvic fractures using 3D volumetric holography:Comparison of plain X-ray and CT.Journal of Computer Assisted Tomography,1995,19:967-974
    25.王劲,张雪林,李树祥等.螺旋CT多平面重建、三维表面遮盖法重建及容积重建技术在骨盆骨折中的临床应用.临床放射学杂志,2001,20(4):302-304
    26.Protorius ES,Fishman ED.Volume-rendered-three-dimensional spiral CT:Muscloskeletal applicational.Radio graphy,1999,19:1143
    27.彭磊,徐春林,魏莉莉.螺旋CT三维重建在骨盆骨折中的应用.CT 理论与应用研究,2002,11(3):39-41
    28.孙泓泓,赵京龙,杨全新.骨骼系统螺旋CT三维重建的技术探讨.陕西医学杂志,2003,35(5):405-407
    29.McCollough CH,Morin RL.The technical design and performance of ultra fast computed tomography.Radio Clin of North Am,1994,32(3):521-536
    30.Seno H,Mizunuma M,Nishida M,et al.3D-CT stereoscopic imaging in maxillofacial surgery.Journal of Tomography,1999,23(2):276-279
    31.Ray CE JR.Application of three-dimensional CT imaging for evaluation of head and neck pathology.Radio Clin of North Am,1993,31(1):181-194
    32.何沙,白桦,戴汝平.电子束CT三维重建方法.CT理论与应用研究,1998,7(4):5-12
    33.陆维举,赵建宁,李斌等.电子束CT三维重建在髋臼骨折诊断与治疗中的应用.骨与关节损伤杂志,2000,15(5):321-322
    34.苏亚辉,吕新生,曹文钢等.快速成型技术在临床医学中的应用。合肥工业大学学报(自然科学版),2002,25(3):411-413
    35.滕勇,王臻,李涤尘.快速成型技术在医学中的应用.国外医学工程分册,2001,24(6):257-261
    36.肖水生.快速成型技术及其在颅颌面外科中的应用.重庆医学,2002,31(12):1250-1251
    37.韩强.快速成型技术在医学领域中的应用.国外口腔医学分册,2002,29(4):257-259
    38.尹庆水,钟世镇.珊瑚羟基磷灰石人工骨的研究进展.中华骨科杂志,1997,17(6):396-398
    39.吴永辉,李涤尘,卢秉恒等.基于RP的人工骨骼制造方法探索.中国机械工程,12(4):392-394
    40.王行仁.先进仿真技术.测控技术,1999,18(6):5-8
    41.杨嘉樨,计算机仿真的进展,计算机仿真,1995,1:1-1
    42.苏建明,张续红,胡庆夕,展望虚拟现实技术,计算机 仿真,2004,21(1):18-21
    43.王正中,复杂系统仿真方法及应用,计算机仿真,2001,1(18):3-6
    44.王正中,屠仁寿.现代计算机仿真技术及应用[M]1 北京:国防工业出版社,1991
    45.王兆其.虚拟人合成研究综述.中国科学院研究生院学报,2000,17(2):89-96
    46.宫可想,周淑秋,常宪平,三维人体建模技术探讨,首都师范大学学报(自然科学版),2003,24(4):17-20
    47.戴克戎.人工关节后期松动的生物学基础.人工关节的基础研究与临床研究,1993,9(3):18-21
    48.尚鹏,于力牛,王成焘,骨改建及其数字仿真的研究进展,北京生物医学工程,2002,21(4):286-289
    49.蔡巧玲,胡大一,医学模拟技术在临床教学中的应用,中华内科杂志,2006,45(5):357-358
    50.Williams PL,Bannister LH,Berry MM,et al.Grayps anatomy.38th ed.New York:Churchill Livingston.1995.528-531,662-676.
    51.陈肃标,强直性脊柱炎,实用医学杂志,2002,18(2):112-113
    52.徐朋,徐达传,高道海等.腰骶部SPR 术中脊神经前后根定位和应用解剖.中国临床解剖学杂志,1999,17(1):1
    53.宋连新;张英泽;彭阿钦;潘进社&垂直不稳定性骨盆骨折内固定的生物力学研究&中华实验外科杂志;2000,17:126-127
    54.Garcia JM,Doblare M,Seral B,Seral F,Palance D,Graica 1,Three-dimensional finite element analysis of several intermal and external pelvis fixations,J Biomech Eng,2000,122:516-522
    55.Radasch RM,Merkley DF,Hoefle WD,Peterson J,Static strength evaluation of sacroiliac fracture-separation repairs.Vet Surg,1990,19:155-161
    56.Matta JM,Saucedo T.Internal fixation of pelvic ring fractures[J].Clin Orthop,1989,242:83-97.
    57.Denis F.The three - column spine and its sighificance in the classificationof acture thoracolumbar sp ine injuries[J].Sp ine,1983,8(8):817-831.
    58.Sims SH,Bosse M,KellamJ.Indications for stabilization of major pelvicdisruption[J].Tech Orthop,1995;9(4):275-282
    59.Garbuglia A,Bossi E,Ronzani C et al.Severe pelvic injuries:indications and techniques of skeletal fixation[J].Chir ltal,1998;50(5-6):61-71
    60.Chip Rouct ML,Smonian PT,Swrontkowski MF.Stabilization of pelvicring disruptions[J].Clin North Am,1997;28(3):369-388
    
    61.RouttML Jr,Nork SE,MillsWJ,et al.Percutaneous fixation of pelvic ring disrup tions.Clin Orthop Relat Res,2000,(375):15-29.
    62.Ebraheim NA,Xu R,Biyani A,et al.Morphologic considerations of thefirst sacral pedicle for iliosacral screw placement.Spine,1997,22(8):841-846.
    63.Edwards CC.Spinal screw fixation of the lumbar spine:early results treating the first 50cases[J].Orthop Trans,1987,11(1):99.
    64.Cotrel y,Dubousset J,Guillaumat M.New universal instrumentation in spinal surgery[J].Clin Orthop,1988,227:10-23.
    65.Guyer DW,Wiltse LL,Peek RD.The Wiltse pedicle screw fixationsystem[J].Orthopedics,1988,11(10):1455-1460.
    66.Krag MH.Biomechanic of thoracolumbar spinal fixation:a review[J].Spine,1991,16(3 suppl):84-99.
    67.Louis R.Fusion of the lumbar and sacral spine by internal fixation with screw plates[J].Clin Orthop,1986,203:18-33.
    68.Steffee AD,Biscup RS,Sitkowski DJ1 Segmental spine plates with pedicle screw fixation:a new internal fixation device for disorders of the lumbar and thoracolumbar spine[J].Clin Orthop,1986,203:45-53.
    69.Harrington PR,Dickson J H.Spinal instrumentation in the treatment of severe progressive spondylolisthesis[J].Clin Orthop,1976,(117):157-163.
    70.龙源深,梁 锦,詹世强,等.改进第1 骶椎椎弓根螺钉进入法的解剖学研究与临床应用[J].中华骨科杂志,1999,19(9):537-540.
    71.黄宗文,饶书城.脊柱腰骶段经椎弓根固定的应用解剖学研究[J].中国脊柱脊髓杂志,1996,6(3):119-122.
    72.杨 凯,赵 海,刘 强,等.正常成人骶1 椎弓根解剖学测量与临床应用[J].中国矫形外科杂志,1998,5(4):320-321.
    73.严 军,郭 春,唐天驷,等.经椎弓根椎体间内固定治疗腰椎滑脱症的应用解剖学研究[J].骨与关节损伤杂志,1996,11(5):278-281.
    74.Xu R,Ebraheim NA,Yeasting RA,et al.Morphometric evaluation of the first sacral vertebra and the projection of its pedicle on the posterior aspect of the sacrum[J].Spine,1995,20(8):936-940.
    75.William WL,Zhu QA,Zhong ShZh,et al.Biomechanics of two triangulated sacral screws for lumbosacral fixation[J].Chin J Spine andSpinal Cord,2000,10(5):292-295.
    吕维加,朱青安,钟世镇,等.双骶骨螺钉成角固定的生物力学分析[J].中国脊柱脊髓杂志,2000,10(5):292-295.
    76.Zhu QA,LuWJ,Holmes Andrew,et al.A biomechanical evaluation of pull - out strength for sacral screw fixation[J].Chin J Orthop,1999,19(8):467-470.
    朱青安,吕维加,Holmes Andrew,等.骶骨螺钉四种固定方式的生物力学分析[J].中华骨科杂志,1999,19(8):467-470.
    77.Smith SA,Abitbol JJ,Carlson GD,et al.The effects of depth of penetration,screw orientation,and bone density on sacral screw fixation[J].Spine,1993,18(8):1006-1010.
    78.Carlson GD,Abitbol JJ,Anderson DR,et al.Screw fixation in the human sacrum:an in vitro study of the biomechanics of fixation[J].i.Spine,1992,17(6 suppl):196-203.
    79.洪华兴,潘志军,黄宗坚,骶髂关节螺钉固定应用及CT与解剖学研究,中国骨伤2004年5月第17卷第5期,270-273.
    80.Keating JF,Werier J,Blachut P,et al.Early fixation of the vertically unstable pelvis:the role of iliosacral screw fixation of the posterior
    lesion[J].Journal of Orthopaedic Trauma,1999,13(2):107-113
    
    81.成 俊,宋跃明,丁方东,内固定结合外固定治疗C型骨盆骨折,四川医学2005年9月第26卷(第9期)1000-1001
    82.Baumgaertner MR.Fractures of the posterior wall of the acetabulum.J Am Acad Orthop Surg,1999,7:54-65
    83.章纯光,海涌,邹德成等.骨骼CT图像的三维重建及临床意义.中国矫形外科杂志,2002,10(9):901-902
    84.苗延巍,伍建林,郎志谨等.螺旋CT三维重建在髋臼骨折的临床应用.中国医学影像技术,2002,12(6):517-519
    85.孙泓泓,赵京龙,杨全新等.骨骼系统螺旋CT三维重建的技术探讨.陕西医学杂志,2003,35(5):405-407
    86.Fishman EK,Magid D,Brooke AF.Fractures of the sacrum and sacroiliac joint:evaluation by computerized tomography with multiple reconstruction.J South Med,1998,81:171-177
    87.薛波,胡勇,徐荣明,CT 引导下空心拉力螺钉内固定治疗骶髂复合体损伤,骨与关节损伤杂志2004年7月第19卷第7期:445-447

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700