乙醇对血管内皮细胞及家兔血液流变学等作用影响的实验研究
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摘要
研究背景
在法医学检验及鉴定中，经常遇到由于饮酒后而引发的刑事案件和民事案件。由于在醉酒状态下容易引起斗殴伤害案件的发生，也可以成为原来患有高血压病、冠心病等心脑血管疾病的死亡诱因。过量饮酒还可直接引起酒精中毒死亡，这就导致了在法医学检验及鉴定中，乙醇、外力及疾病在死亡或伤害后果中的作用、各自应当承担什么样的法律责任、如何诊断及鉴定往往成为一个争论的焦点，而这种鉴定结论却对案件的定罪、量刑有着非常重要的作用，因此有必要对乙醇与机体的作用进行深入的研究，为解决此类问题提供理论基础。
乙醇与心脑血管系统的作用密切相关，而内皮细胞是血管系统的一个重要组成部分，其直接接触血液中的乙醇，又受到血流冲击力的作用。因此本研究应用细胞生物力学的方法，模拟在人体血液循环状态作用下，探讨不同乙醇浓度对血管内皮细胞热休克蛋白(HSP)70表达的影响，以期作为反映乙醇中毒的一个指针。利用扫描电镜观察内皮细胞在不同浓度乙
Background
Some criminal and civilian cases are often encountered irritated by drunken people during the practice of forensic identification and check actions. The injured and deaths are easily aroused by drunken man fighting each other. Alcoholism is one of the inducing causes of the drunken who had the hypertension or coronary heart disease. The death can be also caused by ethanol overtaken. All of these reasons, such as the effect of alcohol, the mild injury, and the disease were in a tangle. Therefore, it is necessary to clarify the proportion of each taken factor. So as to determine the result of ethanol, rate of the force, and to diagnose the disease are the principal points of identification. What's more, the conclusion of identification is very essential to evaluate and sentence the case. So it is necessary to research the effect of ethanol with the human body and provide the theoretical foundation for these events.
Because of affinity relationship of ethanol with the cardiac, vascular and cerebral systems, and because of endothelial cells is the direct site to contact the ethanol in blood flow and to sustain the stress from the flow. The study, using the methods of cellular biomechanics to simulate the circulation of blood
在法医学检验及鉴定中，经常遇到由于饮酒后而引发的刑事案件和民事案件。由于在醉酒状态下容易引起斗殴伤害案件的发生，也可以成为原来患有高血压病、冠心病等心脑血管疾病的死亡诱因。过量饮酒还可直接引起酒精中毒死亡，这就导致了在法医学检验及鉴定中，乙醇、外力及疾病在死亡或伤害后果中的作用、各自应当承担什么样的法律责任、如何诊断及鉴定往往成为一个争论的焦点，而这种鉴定结论却对案件的定罪、量刑有着非常重要的作用，因此有必要对乙醇与机体的作用进行深入的研究，为解决此类问题提供理论基础。
乙醇与心脑血管系统的作用密切相关，而内皮细胞是血管系统的一个重要组成部分，其直接接触血液中的乙醇，又受到血流冲击力的作用。因此本研究应用细胞生物力学的方法，模拟在人体血液循环状态作用下，探讨不同乙醇浓度对血管内皮细胞热休克蛋白(HSP)70表达的影响，以期作为反映乙醇中毒的一个指针。利用扫描电镜观察内皮细胞在不同浓度乙
Background
Some criminal and civilian cases are often encountered irritated by drunken people during the practice of forensic identification and check actions. The injured and deaths are easily aroused by drunken man fighting each other. Alcoholism is one of the inducing causes of the drunken who had the hypertension or coronary heart disease. The death can be also caused by ethanol overtaken. All of these reasons, such as the effect of alcohol, the mild injury, and the disease were in a tangle. Therefore, it is necessary to clarify the proportion of each taken factor. So as to determine the result of ethanol, rate of the force, and to diagnose the disease are the principal points of identification. What's more, the conclusion of identification is very essential to evaluate and sentence the case. So it is necessary to research the effect of ethanol with the human body and provide the theoretical foundation for these events.
Because of affinity relationship of ethanol with the cardiac, vascular and cerebral systems, and because of endothelial cells is the direct site to contact the ethanol in blood flow and to sustain the stress from the flow. The study, using the methods of cellular biomechanics to simulate the circulation of blood
引文
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