胆汁酸（盐）的组装及其磁学性质研究
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摘要
采用Kiliani氧化—Wolff-kishner还原路线合成酮式胆汁酸及胆烷酸，产物经红外光谱、薄层色谱、元素分析、核磁共振谱等表征确证。采用共沉淀法、水热法实现了胆烷酸根在Zn-Al水滑石(LDHs)层间的超分子组装，并用XRD、FT-IR、DSC-TG、TEM和变温磁化强度(SQUID)等手段对样品进行表征，结果表明，直接共沉淀法得到的胆烷酸根插层LDHs结晶度较高、晶相较单一，胆烷酸根在LDHs层间呈与LDHs板层接近平行的有序排列，其磁化率与温度关系表明样品呈现反铁磁交换作用；水热法得到的胆烷酸根插层LDHs，胆烷酸根在LDHs层间呈单层、上下交叉且垂直于层板高度有序排列。采用水热法制备了脱氧胆酸根插层Zn-Al水滑石(LDHs)，建立了脱氧胆酸根插层水滑石的超分子结构模型，即脱氧胆酸根阴离子通过静电力和氢键与LDHs层板相互作用，在层间呈单层、倾斜于层板有序排列。制备了各类正相及反相组装态胆烷酸盐，采用变温磁化强度(SQUID)对其磁学性能进行表征与分析，结果表明，样品主要呈反铁磁性。
The synthesis of cholanic acid was studied using cholic acid as starting material. Structure of the product is characterized by IR, TLC, elementary analysis, and ~1H NMR. Then cholanic acid was succefully intercalated into the Zn-Al Hydrotalcite compound by coprecipition method and hydrothermal method, the sample thereby obtained was characterized using several physicochemical techniques, i.e., XRD、FT-IR、DSC-TG、TEM and SQUID. Results indicated that cholanic acid-pillared Zn-Al hydrotalcite compound with good crystallinity cound be prepared by coprecipition method. Experimental data suggest the anion molecules form a paralleled layer, with the carboxylate groups pointing towards the brucite layers.χ~(-1)～T pattern of the samples show that they all bear antiferromagnetic exchange effect. While the LDH-cholanic intercalation compound synthesized by novel hydrothermal reaction show a different orientation, the cholanic anion form a single perpendicular layer in the interlayer space where the anionic substituents are thought to orient crosswise with each other to the surface of the cationic brucite-like sheet by electrostatic interactions. For the sample with deoxycholate prepared by hydrothermal method, we propose a supramolecular structure which the cholate anions form a tilted layer with their carboxylate groups pointing toward the brucite layer by electrostatic attraction and hydrogen bonding. In addition, the self-assemble cholanic salts are prepared, and their magnetic properties are characterized using SQUID, results show that there are antiferromagnetic exchange effect.
The synthesis of cholanic acid was studied using cholic acid as starting material. Structure of the product is characterized by IR, TLC, elementary analysis, and ~1H NMR. Then cholanic acid was succefully intercalated into the Zn-Al Hydrotalcite compound by coprecipition method and hydrothermal method, the sample thereby obtained was characterized using several physicochemical techniques, i.e., XRD、FT-IR、DSC-TG、TEM and SQUID. Results indicated that cholanic acid-pillared Zn-Al hydrotalcite compound with good crystallinity cound be prepared by coprecipition method. Experimental data suggest the anion molecules form a paralleled layer, with the carboxylate groups pointing towards the brucite layers.χ~(-1)～T pattern of the samples show that they all bear antiferromagnetic exchange effect. While the LDH-cholanic intercalation compound synthesized by novel hydrothermal reaction show a different orientation, the cholanic anion form a single perpendicular layer in the interlayer space where the anionic substituents are thought to orient crosswise with each other to the surface of the cationic brucite-like sheet by electrostatic interactions. For the sample with deoxycholate prepared by hydrothermal method, we propose a supramolecular structure which the cholate anions form a tilted layer with their carboxylate groups pointing toward the brucite layer by electrostatic attraction and hydrogen bonding. In addition, the self-assemble cholanic salts are prepared, and their magnetic properties are characterized using SQUID, results show that there are antiferromagnetic exchange effect.
引文
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