药敷绝骨穴对上肢闭合性骨折患者辅助治疗作用的临床研究
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摘要
骨折可因各种原因发生骨折迟缓愈合和不愈合。因此,缩短骨折痊愈期,提高骨折愈合率,恢复其功能是治疗的关键。近现代的研究表明,中医中药在促进骨折愈合中有明显的临床疗效。绝骨,又名悬钟,为足少阳胆经穴,又为足三阳经之络穴、八会穴中的髓会,为髓气汇聚之处,有补髓壮骨的作用,但其是否有助于骨折的恢复,促进骨折的愈合,有待于进一步临床研究,基于此,本研究通过对中药复方外敷绝骨穴对上肢闭合性骨折患者手术后或复位固定后的辅助治疗作用进行临床疗效观察。
研究目的：
通过对中药复方外敷绝骨穴对骨折患者手术后或复位固定后的辅助治疗作用的临床疗效观察,有助于骨折患者的后续治疗和功能恢复,减轻骨折患者手术及复位固定后的疼痛和肿胀,促进骨折的愈合,减少骨折给患者带来的骨关节畸形和功能障碍,减少骨折对患者生活及工作等的影响,对于中医中药对骨折愈合的治疗以及绝骨穴的临床应用的拓展有一定的指导作用。
研究方法：
将临床90例骨折患者用简单随机分组方法进行分组,分为药敷绝骨穴、药敷三阴交穴组和绝骨穴按摩组,每组患者各30例,分别进行1个月的药敷绝骨穴治疗、药敷三阴交穴治疗和绝骨穴按摩治疗,各组治疗操作方法如下：
1．药敷绝骨穴组：中药处方来自于兴汉中医诊所长期从事中医骨科临床老中医祖传秘方,基本方药如下：补骨脂15克、骨碎补15克、桂枝15克、乳香10克、没药10克等。以上中药制成粉剂装密闭玻璃容器备用,待使用前加生姜汁调成糊状。取穴：于小腿外侧,当外踝尖上3寸,腓骨前缘,取双侧绝骨穴。将调成糊状的中药复方粘于2*3cm的白色胶布上,外敷于双侧绝骨穴,3小时后取下。2天1次,1个月为一疗程,观察一个疗程。
2.药敷三阴交组：中药处方同药敷绝骨穴组,基本方药如下：补骨脂15克、骨碎补15克、桂枝15克、乳香10克、没药10克等。以上中药制成粉剂装密闭玻璃容器备用,待使用前加生姜汁调成糊状。取穴：于小腿内侧,当足内踝尖上3寸,胫骨内侧缘后方。将调成糊状的中药复方粘于2*3cm的白色胶布上,外敷于双侧三阴交穴,3小时后取下。2天1次,1个月为一疗程,观察一个疗程。
3.绝骨穴按摩组：取穴：于小腿外侧,当外踝尖上3寸,腓骨前缘,取双侧绝骨穴。手法：用拇指或掌根、肘关节鹰嘴突按压绝骨穴并稍留30秒,停留5秒后再次按压,如此反复按压5次。2天1次,1个月为一疗程,观察一个疗程。
治疗期间,其他治疗方法按骨科上肢闭合性骨折常规处理方法进行。
一个疗程后观察各项指标并进行比较分析。通过骨折患者在治疗前后以的疼痛、肿胀情况,观察疼痛程度和是否消失及何时消失,并观察患者治疗前后的X光检查结果进行骨折愈合级别判断,观察药敷绝骨穴对骨折患者的辅助治疗作用的效果。
研究结果：
1、药敷绝骨穴对骨折愈合的临床疗效
本研究将90例患者随机分为药敷绝骨穴组、药敷三阴交穴组和绝骨穴按摩组,每组各30例,在3组患者中,治疗前患者的性别比、年龄以及体型无差别；骨折的各种分类无差别；在治疗前患者的疼痛、肿胀程度和X线表现情况无差别；骨折患者的复位和固定方法无差别。
根据骨折患者复位和固定后,使用药敷绝骨穴的方法能促进患者的骨折愈合,有效率为93.33%。
药敷绝骨穴组患者自觉疼痛消失的平均时间(天数)较药敷三阴交穴组和绝骨穴按摩组显著减短,P<0.05,差异有统计学意义。药敷绝骨穴对骨折患者的疼痛症状的治疗效果好。
药敷绝骨穴组患者自觉肿胀消失的平均时间(天数)较药敷三阴交穴组和绝骨穴按摩组显著减短,P<0.05,差异有统计学意义。药敷绝骨穴对骨折患者的肿胀症状的治疗效果好。
药敷绝骨穴组患者在治疗后X线评分结果较药敷三阴交穴组和绝骨穴按摩组显著升高,P<0.05,差异有统计学意义。X线结果评分提示骨折的愈合级别,所以,药敷绝骨穴对骨折患者的愈合级别有提高作用。
本次研究以中药复方外敷绝骨穴,对上肢闭合性骨折患者手术后或复位固定后的辅助治疗作用进行临床疗效观察,药敷绝骨穴组与药敷三阴交穴组相比较,药敷绝骨穴患者自觉疼痛消失的平均时间(天数)、肿胀消失的平均时间(天数)和较药敷三阴交穴组显著减短,P<0.05,差异有统计学意义。在治疗后X线评分结果较药敷三阴交穴组显著升高,P<0.05,差异有统计学意义。
所以,在治疗前患者情况无差别、同样的中药制剂,相同的敷药方法前提下,药敷绝骨穴在对骨折复位和固定后的患者疼痛、肿胀等症状的治疗,以及提示骨折愈合级别的X线情况上,均优于药敷三阴交穴。即绝骨穴有促进骨折愈合的作用,同时能减轻骨折患者手术及复位固定后的疼痛和肿胀,减少骨折给患者带来的骨关节畸形和功能障碍,临床上值得推广应用。
在药敷绝骨穴组患者中,患者治疗前后的生命体征情况平稳,均未发现有瘙痒、过敏等皮肤症状或是其他不良事件的发生。所以药敷绝骨穴是一种安全的治疗方法,治疗时基本对人体无损伤,而且简单方便、没有副作用。
2、中药复方对骨折愈合的促进作用
本次研究采用中药复方来自于兴汉中医诊所长期从事中医骨科临床老中医祖传秘方,基本方药如下：补骨脂15克、骨碎补15克、桂枝15克、乳香10克、没药10克等。以上中药制成粉剂,加水调成糊状外敷用。处方里补骨脂补肾阳、壮筋骨,骨碎补活瘀祛骨风,桂枝温通,乳香没药化瘀消肿,活血止痛。
药敷绝骨穴组与绝骨穴按摩组相比较,药敷绝骨穴患者自觉疼痛消失的平均时间(天数)、自觉肿胀消失的平均时间(天数)和较绝骨穴按摩组显著减短,且P<0.05,差异有统计学意义。在治疗后X线评分结果较绝骨穴按摩组显著升高,且P<0.05,差异有统计学意义。
所以,在治疗前患者情况无差别、同样的选穴的前提下,药敷绝骨穴在对骨折复位和固定后的患者疼痛、肿胀等症状的治疗,以及提示骨折愈合级别的X线情况上,均优于绝骨穴按摩。即中药复方有促进骨折愈合的作用,同时能减轻骨折患者手术及复位固定后的疼痛和肿胀,减少骨折给患者带来的骨关节畸形和功能障碍,临床上值得推广应用。
3、骨折的发生与患者的年龄、性别、体型的关系以及骨折分类的研究
在收集的90例患者中,骨折的发生与患者的年龄有关,老年人更容易发生骨折。骨折的发生与性别与体型无关。临床的骨折患者按骨折的各种分类方法统计,以闭合性骨折、完全骨折、粉碎性骨折、长骨骨干骨折、不稳定骨折为主。临床骨折的治疗方法以手术复位和内固定方法为主。
结论：
1、根据骨折患者复位和固定后,使用药敷绝骨穴的方法能促进患者的骨折愈合,有效率为93.33%,且疗效优于药敷三阴交穴和绝骨穴按摩。
2、绝骨穴和中药复方均有促进骨折愈合的作用,在临床上值得推广。
3、药敷绝骨穴是一种安全的治疗方法,治疗时基本对人体无损伤,而且简单方便、没有副作用。
Purpose:
To be useful for functional recovery and follow-up treatment for fracture patients; to reduce the pain and swelling after surgery and reset-fixed operation; to promote the wound healing; to avoid the joint deformity and dysfunction due to fracture; to reduce the adverse effects for life and work according to the clinical observation of aid effect of Juegu point external application with herbal formula for fracture; which is certain meaningful for fracture teatment with herb and clinical application of Juegu point.
Method:
Observe whether the pain from fracture disappear or not and when the pain disappear; observe the fracture healing level by contrasting X-ray result before and after treatment; observe the aid clinical efficacy of Juegu point external application with herbal formula for fracture by evaluating the situation of pain and swelling before and after treatment for fracture patient. Method:The 90 cases were divided into three groups as Juegu point external application by herbal formula with 30 cases(Group 1), Sanyinjiao point external application by herbal formula with 30 cases(Group 2) and Juegu point massage with 30 cases (Group 3). Use external application and massage to cure corresponding group for two months. Then study and analyse the different indexes.
Result:
1. The clinical efficacy of Juegu point external application for fracture
The research devide 90 cases into three groups as Juegu point external application by herbal formula with 30 cases(Group 1), Sanyinjiao point external application by herbal formula with 30 cases(Group 2) and Juegu point massage with 30 cases (Group 3). There were no difference between three groups in gender, age, size, type of fracture, degree of pain, swelling and X-ray result before treatment, method of reset-fixed operation.
According to the clinical symptoms and signs, the therapy of Juegu point external application with herbal fomula has significant clinical result for fracture patient, the total efficient reach 93.33%.
The average number of days of pain disappear of Group 1 is shorter than that of Group 2 and Group 3, which had statistical significance (P<0.05). The therapy of Juegu point external application with herbal fomula has better effect than others in reducing the pain from fracture.
The average number of days of swelling disappear of Group 1 is shorter than that of Group 2 and Group 3, which had statistical significance (P<0.05) The therapy of Juegu point external application with herbal fomula has better effect than others in eliminating the swelling from fracture.
The score of X-ray of Group 1 is higher than that of Group 2 and Group 3, which had statistical significance (P<0.05). The therapy of Juegu point external application with herbal fomula has better effect than others in improving the fracture healing level.
Among the 30 cases from Group 1, there were no significant difference about vital signs between before and after treatment, and there were no occurrence of pruritus or skin allergies or other harmful matters. Therefore, the therapy is security, simple, conveniet and no side-effect, also had no injury for human body.
2. The effect of promoting the fracture healing by Juegu point
Between Group 1 and Group 2, the average number of days of pain and swelling disappear of Group 1 is shorter than that of Group 2, which had statistical significance (P<0.05); the score of X-ray of Group 1 is higher than that of Group 2, which had statistical signif icance(P<0.05), according to the clinical observation of aid effect of Juegu point external application with herbal formula for fracture patient after surgery and reset-fixed operation.
Therefore, in the case of the same situation before treatment, the same herbal formula and the same external application method, the therapy of Juegu point external application with herbal formula is better than Sanyinjiao point in reducing pain and swelling and improving X-ray score for fracture patient after surgery and reset-fixed operation. That is to say, the therapy is worth with promotion in clinic.
3. The effect of promoting the fracture healing by herbal formula
The herbal formula composition:Buguzhi(15 gram), Gusuibu(15 gram), Guizhi (15 gram), Ruxiang(10 gram), Moyao(10 gram). Mix the above herbs into powder, then add water to them till forming the paste appearance. Use for external application.
Between Group 1 and Group 3, the average number of days of pain and swelling disappear of Group 1 is shorter than that of Group 3, which had statistical significance (P<0.05); the score of X-ray of Group 1 is higher than that of Group 3, which had statistical signif icance(P<0.05), according to the clinical observation of aid effect of Juegu point external application with herbal formula for fracture patient after surgery and reset-fixed operation.
Therefore, in the case of the same situation before treatment, the same herbal formula and the same external application method, the therapy of Juegu point external application with herbal formula is better than massage in reducing pain and swelling and improving X-ray score for fracture patient after surgery and reset-fixed operation. That is to say, the herbal formula is worth with promotion in clinic.
4. The research of the relationship between the occurance of fracture and the age, sex, body type of patient and the type of fracture
Among the 90 cases, the occurance of fracture is related with age but not related with sex and body type. That is to say, the old people is easier to be happen. The main types of fracture include closed fracture, complete fracture, smashed fracture, longbone-backbone fracture and unstable fracture. The reset operation and the fixation are the common treatment.
Conclusion:
1. According to the clinical symptoms and signs, the therapy of Juegu point external application with herbal fomula has significant clinical result for fracture patient, is better than Sanyinjiao point and massage; the total efficient reach 93.33%.
2. Both Juegu point and the herbal formula can promote the fracture healing; which is worth with promotion in clinic.
3. The therapy of Juegu point external application with herbal fomula is security, simple, conveniet and no side-effect, also had no injury for human body.
研究目的：
通过对中药复方外敷绝骨穴对骨折患者手术后或复位固定后的辅助治疗作用的临床疗效观察,有助于骨折患者的后续治疗和功能恢复,减轻骨折患者手术及复位固定后的疼痛和肿胀,促进骨折的愈合,减少骨折给患者带来的骨关节畸形和功能障碍,减少骨折对患者生活及工作等的影响,对于中医中药对骨折愈合的治疗以及绝骨穴的临床应用的拓展有一定的指导作用。
研究方法：
将临床90例骨折患者用简单随机分组方法进行分组,分为药敷绝骨穴、药敷三阴交穴组和绝骨穴按摩组,每组患者各30例,分别进行1个月的药敷绝骨穴治疗、药敷三阴交穴治疗和绝骨穴按摩治疗,各组治疗操作方法如下：
1．药敷绝骨穴组：中药处方来自于兴汉中医诊所长期从事中医骨科临床老中医祖传秘方,基本方药如下：补骨脂15克、骨碎补15克、桂枝15克、乳香10克、没药10克等。以上中药制成粉剂装密闭玻璃容器备用,待使用前加生姜汁调成糊状。取穴：于小腿外侧,当外踝尖上3寸,腓骨前缘,取双侧绝骨穴。将调成糊状的中药复方粘于2*3cm的白色胶布上,外敷于双侧绝骨穴,3小时后取下。2天1次,1个月为一疗程,观察一个疗程。
2.药敷三阴交组：中药处方同药敷绝骨穴组,基本方药如下：补骨脂15克、骨碎补15克、桂枝15克、乳香10克、没药10克等。以上中药制成粉剂装密闭玻璃容器备用,待使用前加生姜汁调成糊状。取穴：于小腿内侧,当足内踝尖上3寸,胫骨内侧缘后方。将调成糊状的中药复方粘于2*3cm的白色胶布上,外敷于双侧三阴交穴,3小时后取下。2天1次,1个月为一疗程,观察一个疗程。
3.绝骨穴按摩组：取穴：于小腿外侧,当外踝尖上3寸,腓骨前缘,取双侧绝骨穴。手法：用拇指或掌根、肘关节鹰嘴突按压绝骨穴并稍留30秒,停留5秒后再次按压,如此反复按压5次。2天1次,1个月为一疗程,观察一个疗程。
治疗期间,其他治疗方法按骨科上肢闭合性骨折常规处理方法进行。
一个疗程后观察各项指标并进行比较分析。通过骨折患者在治疗前后以的疼痛、肿胀情况,观察疼痛程度和是否消失及何时消失,并观察患者治疗前后的X光检查结果进行骨折愈合级别判断,观察药敷绝骨穴对骨折患者的辅助治疗作用的效果。
研究结果：
1、药敷绝骨穴对骨折愈合的临床疗效
本研究将90例患者随机分为药敷绝骨穴组、药敷三阴交穴组和绝骨穴按摩组,每组各30例,在3组患者中,治疗前患者的性别比、年龄以及体型无差别；骨折的各种分类无差别；在治疗前患者的疼痛、肿胀程度和X线表现情况无差别；骨折患者的复位和固定方法无差别。
根据骨折患者复位和固定后,使用药敷绝骨穴的方法能促进患者的骨折愈合,有效率为93.33%。
药敷绝骨穴组患者自觉疼痛消失的平均时间(天数)较药敷三阴交穴组和绝骨穴按摩组显著减短,P<0.05,差异有统计学意义。药敷绝骨穴对骨折患者的疼痛症状的治疗效果好。
药敷绝骨穴组患者自觉肿胀消失的平均时间(天数)较药敷三阴交穴组和绝骨穴按摩组显著减短,P<0.05,差异有统计学意义。药敷绝骨穴对骨折患者的肿胀症状的治疗效果好。
药敷绝骨穴组患者在治疗后X线评分结果较药敷三阴交穴组和绝骨穴按摩组显著升高,P<0.05,差异有统计学意义。X线结果评分提示骨折的愈合级别,所以,药敷绝骨穴对骨折患者的愈合级别有提高作用。
本次研究以中药复方外敷绝骨穴,对上肢闭合性骨折患者手术后或复位固定后的辅助治疗作用进行临床疗效观察,药敷绝骨穴组与药敷三阴交穴组相比较,药敷绝骨穴患者自觉疼痛消失的平均时间(天数)、肿胀消失的平均时间(天数)和较药敷三阴交穴组显著减短,P<0.05,差异有统计学意义。在治疗后X线评分结果较药敷三阴交穴组显著升高,P<0.05,差异有统计学意义。
所以,在治疗前患者情况无差别、同样的中药制剂,相同的敷药方法前提下,药敷绝骨穴在对骨折复位和固定后的患者疼痛、肿胀等症状的治疗,以及提示骨折愈合级别的X线情况上,均优于药敷三阴交穴。即绝骨穴有促进骨折愈合的作用,同时能减轻骨折患者手术及复位固定后的疼痛和肿胀,减少骨折给患者带来的骨关节畸形和功能障碍,临床上值得推广应用。
在药敷绝骨穴组患者中,患者治疗前后的生命体征情况平稳,均未发现有瘙痒、过敏等皮肤症状或是其他不良事件的发生。所以药敷绝骨穴是一种安全的治疗方法,治疗时基本对人体无损伤,而且简单方便、没有副作用。
2、中药复方对骨折愈合的促进作用
本次研究采用中药复方来自于兴汉中医诊所长期从事中医骨科临床老中医祖传秘方,基本方药如下：补骨脂15克、骨碎补15克、桂枝15克、乳香10克、没药10克等。以上中药制成粉剂,加水调成糊状外敷用。处方里补骨脂补肾阳、壮筋骨,骨碎补活瘀祛骨风,桂枝温通,乳香没药化瘀消肿,活血止痛。
药敷绝骨穴组与绝骨穴按摩组相比较,药敷绝骨穴患者自觉疼痛消失的平均时间(天数)、自觉肿胀消失的平均时间(天数)和较绝骨穴按摩组显著减短,且P<0.05,差异有统计学意义。在治疗后X线评分结果较绝骨穴按摩组显著升高,且P<0.05,差异有统计学意义。
所以,在治疗前患者情况无差别、同样的选穴的前提下,药敷绝骨穴在对骨折复位和固定后的患者疼痛、肿胀等症状的治疗,以及提示骨折愈合级别的X线情况上,均优于绝骨穴按摩。即中药复方有促进骨折愈合的作用,同时能减轻骨折患者手术及复位固定后的疼痛和肿胀,减少骨折给患者带来的骨关节畸形和功能障碍,临床上值得推广应用。
3、骨折的发生与患者的年龄、性别、体型的关系以及骨折分类的研究
在收集的90例患者中,骨折的发生与患者的年龄有关,老年人更容易发生骨折。骨折的发生与性别与体型无关。临床的骨折患者按骨折的各种分类方法统计,以闭合性骨折、完全骨折、粉碎性骨折、长骨骨干骨折、不稳定骨折为主。临床骨折的治疗方法以手术复位和内固定方法为主。
结论：
1、根据骨折患者复位和固定后,使用药敷绝骨穴的方法能促进患者的骨折愈合,有效率为93.33%,且疗效优于药敷三阴交穴和绝骨穴按摩。
2、绝骨穴和中药复方均有促进骨折愈合的作用,在临床上值得推广。
3、药敷绝骨穴是一种安全的治疗方法,治疗时基本对人体无损伤,而且简单方便、没有副作用。
Purpose:
To be useful for functional recovery and follow-up treatment for fracture patients; to reduce the pain and swelling after surgery and reset-fixed operation; to promote the wound healing; to avoid the joint deformity and dysfunction due to fracture; to reduce the adverse effects for life and work according to the clinical observation of aid effect of Juegu point external application with herbal formula for fracture; which is certain meaningful for fracture teatment with herb and clinical application of Juegu point.
Method:
Observe whether the pain from fracture disappear or not and when the pain disappear; observe the fracture healing level by contrasting X-ray result before and after treatment; observe the aid clinical efficacy of Juegu point external application with herbal formula for fracture by evaluating the situation of pain and swelling before and after treatment for fracture patient. Method:The 90 cases were divided into three groups as Juegu point external application by herbal formula with 30 cases(Group 1), Sanyinjiao point external application by herbal formula with 30 cases(Group 2) and Juegu point massage with 30 cases (Group 3). Use external application and massage to cure corresponding group for two months. Then study and analyse the different indexes.
Result:
1. The clinical efficacy of Juegu point external application for fracture
The research devide 90 cases into three groups as Juegu point external application by herbal formula with 30 cases(Group 1), Sanyinjiao point external application by herbal formula with 30 cases(Group 2) and Juegu point massage with 30 cases (Group 3). There were no difference between three groups in gender, age, size, type of fracture, degree of pain, swelling and X-ray result before treatment, method of reset-fixed operation.
According to the clinical symptoms and signs, the therapy of Juegu point external application with herbal fomula has significant clinical result for fracture patient, the total efficient reach 93.33%.
The average number of days of pain disappear of Group 1 is shorter than that of Group 2 and Group 3, which had statistical significance (P<0.05). The therapy of Juegu point external application with herbal fomula has better effect than others in reducing the pain from fracture.
The average number of days of swelling disappear of Group 1 is shorter than that of Group 2 and Group 3, which had statistical significance (P<0.05) The therapy of Juegu point external application with herbal fomula has better effect than others in eliminating the swelling from fracture.
The score of X-ray of Group 1 is higher than that of Group 2 and Group 3, which had statistical significance (P<0.05). The therapy of Juegu point external application with herbal fomula has better effect than others in improving the fracture healing level.
Among the 30 cases from Group 1, there were no significant difference about vital signs between before and after treatment, and there were no occurrence of pruritus or skin allergies or other harmful matters. Therefore, the therapy is security, simple, conveniet and no side-effect, also had no injury for human body.
2. The effect of promoting the fracture healing by Juegu point
Between Group 1 and Group 2, the average number of days of pain and swelling disappear of Group 1 is shorter than that of Group 2, which had statistical significance (P<0.05); the score of X-ray of Group 1 is higher than that of Group 2, which had statistical signif icance(P<0.05), according to the clinical observation of aid effect of Juegu point external application with herbal formula for fracture patient after surgery and reset-fixed operation.
Therefore, in the case of the same situation before treatment, the same herbal formula and the same external application method, the therapy of Juegu point external application with herbal formula is better than Sanyinjiao point in reducing pain and swelling and improving X-ray score for fracture patient after surgery and reset-fixed operation. That is to say, the therapy is worth with promotion in clinic.
3. The effect of promoting the fracture healing by herbal formula
The herbal formula composition:Buguzhi(15 gram), Gusuibu(15 gram), Guizhi (15 gram), Ruxiang(10 gram), Moyao(10 gram). Mix the above herbs into powder, then add water to them till forming the paste appearance. Use for external application.
Between Group 1 and Group 3, the average number of days of pain and swelling disappear of Group 1 is shorter than that of Group 3, which had statistical significance (P<0.05); the score of X-ray of Group 1 is higher than that of Group 3, which had statistical signif icance(P<0.05), according to the clinical observation of aid effect of Juegu point external application with herbal formula for fracture patient after surgery and reset-fixed operation.
Therefore, in the case of the same situation before treatment, the same herbal formula and the same external application method, the therapy of Juegu point external application with herbal formula is better than massage in reducing pain and swelling and improving X-ray score for fracture patient after surgery and reset-fixed operation. That is to say, the herbal formula is worth with promotion in clinic.
4. The research of the relationship between the occurance of fracture and the age, sex, body type of patient and the type of fracture
Among the 90 cases, the occurance of fracture is related with age but not related with sex and body type. That is to say, the old people is easier to be happen. The main types of fracture include closed fracture, complete fracture, smashed fracture, longbone-backbone fracture and unstable fracture. The reset operation and the fixation are the common treatment.
Conclusion:
1. According to the clinical symptoms and signs, the therapy of Juegu point external application with herbal fomula has significant clinical result for fracture patient, is better than Sanyinjiao point and massage; the total efficient reach 93.33%.
2. Both Juegu point and the herbal formula can promote the fracture healing; which is worth with promotion in clinic.
3. The therapy of Juegu point external application with herbal fomula is security, simple, conveniet and no side-effect, also had no injury for human body.
引文
[1]李万平.手法整复、小夹板外固定配合中药辨证分期治疗中老年肱骨下段粉碎性骨折75例[J].中医药导报.2008,14(4)：54
[2]罗换新,赵学文,冀海源等.序贯疗法治疗骨折的对照研究[J].四川中医.2008,26(5)：92-93
[3]沈勇灵.中药骨伤液湿敷治疗闭合骨折消肿止痛的疗效观[J].现代保健：医学创新研究.2008,5(15)：171-172
[4]杨雄健,吴俊哲,陈敢峰.手术内固定+中药辨证治疗距骨骨折[J].当代医学.2008,9：150-151
[5]彭尚军,徐无忌,郭星等.锁定加压接骨板结合中药治疗人工髋关节股骨假体周围骨折临床研究[J].新中医.2007,39(8)：44-45
[6]朱惠芳,朱炜.中药熏洗对髌骨骨折后膝关节功能恢复的治疗作用[J].中医药临床杂志.2007,19(2)：165-166
[7]谢艳.中药促进骨折愈合的机制[J].四川中医．2008,26(4)：51—54
[8]胡学武,游长征,熊辉.中医药促进骨折愈合分子机理研究进展[J].中医药导报.2006,12(10)：79-81
[9]高大伟,苏培基,伍中庆等.中药促进骨折愈合临床文献的Meta分析[J].中国矫形外科杂志.2008,16(12)：913-916
[10]侯晓峰,刘景生.中药促进骨折愈合机理[J].中国中医骨伤科杂志,2003,11(2)：61
[11]阮朝阳.中药促进骨折愈合作用机制的实验研究进展[J].湖南中医药导报,2003,9(2)：49
[12]刘钟华,杨世荣,回春.中药促进骨折愈合的实验研究概况(J].长春中医学院学报,2004,20(2)：63
[13]符诗聪,杜宁,史炜镔,等.丹参有效部位对骨折愈合影响的生物力学实验研究[J].中国中西医结合杂志,1999,19(2)：106
[14]李也白,温宏,徐华梓,等.复合中药制剂促进骨折愈合的实验研究[J].骨与关节损伤杂志,1999,14(2)：108
[15]周秋丽,王丽娟,郭颖杰,等.鹿茸多肽对实验性骨折的治疗作用及机理研究[J].白求恩医科大学学报,1999,25(5)：586
[16]柳海峰,杨佩荪,陈晋杰,等.三花接骨散对骨折鼠垂体生长激素细胞的影响[J].中国中医骨伤科杂志,1998,6(5)：7
[17]徐东艳,应健跃.中药促进骨折愈合的研究进展(J].浙江中医杂志,2005,(3)：137
[18]程志安,吴燕峰,黄智清,等.续断对成骨细胞增殖、分化、凋亡和细胞周期的影响.中医正骨,2004,16(12)：1
[19]王华松,黄琼霞,许申明.骨碎补对骨折愈合中血生化指TGF—表达的影响.中医正骨,2001,13(5)：6
[20]张治国,崔大领.“张氏接骨散”促进骨折愈合的临床观察(J].中医药研究,1995,15(5)：9
[21]朱以锦.化痰祛瘀补肾治疗股骨颈骨折延迟愈合30例[J].四川中医,2002,20(12)：63
[22]蒋顺琬,杨卓欣,林志文.壮筋补骨丸促进骨折愈合的临床研究[J].广州中医药大学学报,2004,2(15)：373
[23]田玉环,付爱平,刘国胜.正奇接骨丹颗粒剂治疗创伤骨折临床研究[J].中国实验方剂学杂志,2004,10(4)：61
[24]张建国,陈良金,蒋文跃.外敷中药对骨折愈合微血管重建的影响[J].中国骨伤,2000,13(2)：86
[25]杜华山,黄伟流,赖志峰,等.黄油纱布外敷促进骨折愈合1130例[J].湖南中医杂志,2005,21(2)：60
[26]张晓燕,吴铁.针灸促进骨折愈合的研究现状[J].河北中医,2005,27(7)：548
[27]张俐,吴炳煌,移平,等.针灸对骨折家兔促甲状腺激素的影响[J].福建中医学院学报,1999,9(1)：29
[28]王文远.针刺臀痛穴对大白兔下肢软组织损伤修复的影响[J].中国矫形外科杂志,1997,4(4)：312
[29]]张俐,张安桢,移平.针灸促进骨折愈合的红外热像图观察[J].中国骨伤,2001,14(8)：468-470
[30]]张俐,移平,吴炳煌,等.针灸对骨折家兔微量元素的影响[J].中国中医骨伤科杂志,1999,7(5)：1-5
[31]]张秀花,丁永清,陈静.针刺对体内微量元素变化的影响[J].中国中医药科技,2002,9(2)：66
[32]]吴明霞,吴炳煌,刘献祥,等.艾灸对绝经后骨质疏松症影响的实验和临床研究[J].中国针灸,2002,22(5)：334-336
[33]]祁晓华,聂明,沈梅红,等.针刺对骨折家兔甲状腺功能的影响[J].南京中医药大学学报(自然科学版),2001,17(2)：111-112
[34]]李心沁,王琳,单秋华.针刺对大鼠骨折愈合及骨痂TGF—p1表达的影响[J].山东中医杂志,2006,25(8)： 546—548
[35]熊芳丽,肖亚平.针灸促进骨折愈合的临床观察[J].中国针灸,1997,17(11)：685
[36]粱贵生.针刺艾灸治疗胫腓骨骨折延迟愈合临床体会(J].中医药学报,2000,(2)：59
[37]周黎明.电针治疗J拴腓骨骨折延迟愈合52例疗效观察[J].中国针灸,2000,(10)：599
[38]]刘家瑞.穴位注射配合物理疗法治疗胸腰椎压缩性骨折[J].中国康复,2006,21(3)：198
[39]杨镇萍,建.脉络宁穴位注射促进骨愈合的临床应用[J].长春中医学医学报,2002,18(3)：39-40
[40]]郑海涛,梁丽华.针刺配合穴位注射治疗骨折迟缓愈合32例[J].实用中医药杂志,2004,20(3)：129
[41]]王全权,陈海林,张兴国.穴位注射结合中药促进尺桡骨骨折愈合的疗效观察[J].成都中医药大学学报,2005,28(2)：23-24
[42]赵臣来,郭加利.独取绝骨治疗急性腰扭伤50例[J].针灸临床杂志.2003,19(3)：37
[43]杜永平,陈蓓琳,严君白.悬钟穴治疗枕大神经痛33例[J].针灸临床杂志.1995,11(9)：42
[44]米德萍.针刺绝骨治疗落枕38例疗效观察[J].云南中医中药杂志.2005,26(1)：28
[45]孙朝辉,冯彩霞.针刺悬钟配阿是穴治疗骨科术后疼痛[J].中国针灸.2007,27(12)：895-897
[46]周亚娜,向楠,李家康等.针刺治疗原发性骨质疏松症96例临床观察[J].湖北巾医学院学报.2004,12(6)：82—83
[47]赵利华,文建军.艾炷灸足三里、悬钟对衰老小鼠学习记忆及脑NONOS的影响[J].辽宁中医药大学学报.2008,10(9)：148—151
[48]陈文,顾红卫,马维平等.针刺足三里、悬钟对缺血性中风患者脑血管功能的影响：多中心随机对照研究[J].中国针灸.2006,26(12)：851-853
[49]邓柏颖,谢感共.化脓灸法对血液流变学指标近期影响的观察[J].中医药学刊.2003,21(3)：372
[50]中药新药临床研究指导原则.中国医药科技出版社,2002
[51]胥少汀,葛宝丰,徐印坎.实用骨科学.人民军医出版社,2005
[52]顾玉东,王澍寰,侍德.手外科手术学[M].上海：上海医科大学出版社,1999：379-380
[53]南登崑.康复医学,北京：人民卫生出版社,2004,第3版
[54]陈丽茹.艾炷灸膈俞、绝骨穴调节实验性大鼠骨髓造血与免疫功能紊乱的研究[D].成都中医药大学,2000.
[55]闫玉玲.艾炷灸膈俞、绝骨调节实验性大鼠造血机能紊乱的研究[D].成都中医药大学,1999.
[2]罗换新,赵学文,冀海源等.序贯疗法治疗骨折的对照研究[J].四川中医.2008,26(5)：92-93
[3]沈勇灵.中药骨伤液湿敷治疗闭合骨折消肿止痛的疗效观[J].现代保健：医学创新研究.2008,5(15)：171-172
[4]杨雄健,吴俊哲,陈敢峰.手术内固定+中药辨证治疗距骨骨折[J].当代医学.2008,9：150-151
[5]彭尚军,徐无忌,郭星等.锁定加压接骨板结合中药治疗人工髋关节股骨假体周围骨折临床研究[J].新中医.2007,39(8)：44-45
[6]朱惠芳,朱炜.中药熏洗对髌骨骨折后膝关节功能恢复的治疗作用[J].中医药临床杂志.2007,19(2)：165-166
[7]谢艳.中药促进骨折愈合的机制[J].四川中医．2008,26(4)：51—54
[8]胡学武,游长征,熊辉.中医药促进骨折愈合分子机理研究进展[J].中医药导报.2006,12(10)：79-81
[9]高大伟,苏培基,伍中庆等.中药促进骨折愈合临床文献的Meta分析[J].中国矫形外科杂志.2008,16(12)：913-916
[10]侯晓峰,刘景生.中药促进骨折愈合机理[J].中国中医骨伤科杂志,2003,11(2)：61
[11]阮朝阳.中药促进骨折愈合作用机制的实验研究进展[J].湖南中医药导报,2003,9(2)：49
[12]刘钟华,杨世荣,回春.中药促进骨折愈合的实验研究概况(J].长春中医学院学报,2004,20(2)：63
[13]符诗聪,杜宁,史炜镔,等.丹参有效部位对骨折愈合影响的生物力学实验研究[J].中国中西医结合杂志,1999,19(2)：106
[14]李也白,温宏,徐华梓,等.复合中药制剂促进骨折愈合的实验研究[J].骨与关节损伤杂志,1999,14(2)：108
[15]周秋丽,王丽娟,郭颖杰,等.鹿茸多肽对实验性骨折的治疗作用及机理研究[J].白求恩医科大学学报,1999,25(5)：586
[16]柳海峰,杨佩荪,陈晋杰,等.三花接骨散对骨折鼠垂体生长激素细胞的影响[J].中国中医骨伤科杂志,1998,6(5)：7
[17]徐东艳,应健跃.中药促进骨折愈合的研究进展(J].浙江中医杂志,2005,(3)：137
[18]程志安,吴燕峰,黄智清,等.续断对成骨细胞增殖、分化、凋亡和细胞周期的影响.中医正骨,2004,16(12)：1
[19]王华松,黄琼霞,许申明.骨碎补对骨折愈合中血生化指TGF—表达的影响.中医正骨,2001,13(5)：6
[20]张治国,崔大领.“张氏接骨散”促进骨折愈合的临床观察(J].中医药研究,1995,15(5)：9
[21]朱以锦.化痰祛瘀补肾治疗股骨颈骨折延迟愈合30例[J].四川中医,2002,20(12)：63
[22]蒋顺琬,杨卓欣,林志文.壮筋补骨丸促进骨折愈合的临床研究[J].广州中医药大学学报,2004,2(15)：373
[23]田玉环,付爱平,刘国胜.正奇接骨丹颗粒剂治疗创伤骨折临床研究[J].中国实验方剂学杂志,2004,10(4)：61
[24]张建国,陈良金,蒋文跃.外敷中药对骨折愈合微血管重建的影响[J].中国骨伤,2000,13(2)：86
[25]杜华山,黄伟流,赖志峰,等.黄油纱布外敷促进骨折愈合1130例[J].湖南中医杂志,2005,21(2)：60
[26]张晓燕,吴铁.针灸促进骨折愈合的研究现状[J].河北中医,2005,27(7)：548
[27]张俐,吴炳煌,移平,等.针灸对骨折家兔促甲状腺激素的影响[J].福建中医学院学报,1999,9(1)：29
[28]王文远.针刺臀痛穴对大白兔下肢软组织损伤修复的影响[J].中国矫形外科杂志,1997,4(4)：312
[29]]张俐,张安桢,移平.针灸促进骨折愈合的红外热像图观察[J].中国骨伤,2001,14(8)：468-470
[30]]张俐,移平,吴炳煌,等.针灸对骨折家兔微量元素的影响[J].中国中医骨伤科杂志,1999,7(5)：1-5
[31]]张秀花,丁永清,陈静.针刺对体内微量元素变化的影响[J].中国中医药科技,2002,9(2)：66
[32]]吴明霞,吴炳煌,刘献祥,等.艾灸对绝经后骨质疏松症影响的实验和临床研究[J].中国针灸,2002,22(5)：334-336
[33]]祁晓华,聂明,沈梅红,等.针刺对骨折家兔甲状腺功能的影响[J].南京中医药大学学报(自然科学版),2001,17(2)：111-112
[34]]李心沁,王琳,单秋华.针刺对大鼠骨折愈合及骨痂TGF—p1表达的影响[J].山东中医杂志,2006,25(8)： 546—548
[35]熊芳丽,肖亚平.针灸促进骨折愈合的临床观察[J].中国针灸,1997,17(11)：685
[36]粱贵生.针刺艾灸治疗胫腓骨骨折延迟愈合临床体会(J].中医药学报,2000,(2)：59
[37]周黎明.电针治疗J拴腓骨骨折延迟愈合52例疗效观察[J].中国针灸,2000,(10)：599
[38]]刘家瑞.穴位注射配合物理疗法治疗胸腰椎压缩性骨折[J].中国康复,2006,21(3)：198
[39]杨镇萍,建.脉络宁穴位注射促进骨愈合的临床应用[J].长春中医学医学报,2002,18(3)：39-40
[40]]郑海涛,梁丽华.针刺配合穴位注射治疗骨折迟缓愈合32例[J].实用中医药杂志,2004,20(3)：129
[41]]王全权,陈海林,张兴国.穴位注射结合中药促进尺桡骨骨折愈合的疗效观察[J].成都中医药大学学报,2005,28(2)：23-24
[42]赵臣来,郭加利.独取绝骨治疗急性腰扭伤50例[J].针灸临床杂志.2003,19(3)：37
[43]杜永平,陈蓓琳,严君白.悬钟穴治疗枕大神经痛33例[J].针灸临床杂志.1995,11(9)：42
[44]米德萍.针刺绝骨治疗落枕38例疗效观察[J].云南中医中药杂志.2005,26(1)：28
[45]孙朝辉,冯彩霞.针刺悬钟配阿是穴治疗骨科术后疼痛[J].中国针灸.2007,27(12)：895-897
[46]周亚娜,向楠,李家康等.针刺治疗原发性骨质疏松症96例临床观察[J].湖北巾医学院学报.2004,12(6)：82—83
[47]赵利华,文建军.艾炷灸足三里、悬钟对衰老小鼠学习记忆及脑NONOS的影响[J].辽宁中医药大学学报.2008,10(9)：148—151
[48]陈文,顾红卫,马维平等.针刺足三里、悬钟对缺血性中风患者脑血管功能的影响：多中心随机对照研究[J].中国针灸.2006,26(12)：851-853
[49]邓柏颖,谢感共.化脓灸法对血液流变学指标近期影响的观察[J].中医药学刊.2003,21(3)：372
[50]中药新药临床研究指导原则.中国医药科技出版社,2002
[51]胥少汀,葛宝丰,徐印坎.实用骨科学.人民军医出版社,2005
[52]顾玉东,王澍寰,侍德.手外科手术学[M].上海：上海医科大学出版社,1999：379-380
[53]南登崑.康复医学,北京：人民卫生出版社,2004,第3版
[54]陈丽茹.艾炷灸膈俞、绝骨穴调节实验性大鼠骨髓造血与免疫功能紊乱的研究[D].成都中医药大学,2000.
[55]闫玉玲.艾炷灸膈俞、绝骨调节实验性大鼠造血机能紊乱的研究[D].成都中医药大学,1999.