中药溻渍治疗膝骨性关节炎的临床研究
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摘要
目的:膝骨性关节炎是中老年人的常见病、多发病,严重的影响中老年人的生活质量,成为全球性的公共卫生问题之一。膝骨性关节炎的有效预防与治疗已成为当务之急,本着科研服务社会的宗旨,本次研究试图为膝骨性关节炎的治疗找到一种安全、方便、持续有效的治疗途径。
方法:将符合纳入标准的60例膝骨性关节炎患者,按随机原则分为治疗组和对照组,每组30例,治疗组给予中药溻渍外敷治疗,对照组给予TDP(特定电磁波)治疗仪照射治疗。并将治疗前、治疗后的临床症状分别根据《中药新药临床研究指导原则》的标准给予评分,将所得数据经spssl2. 0统计软件进行统计学分析,客观评价两种治疗方法的临床治疗效果。
结果:治疗组总有效率为90.00%,对照组总有效率为76.67%,治疗组疗效明显高于对照组(P<0.05)。
结论:中药溻渍治疗膝骨性关节炎的疗效显著,证实了中药溻渍治疗的有效性,拓宽了膝骨性关节炎的治疗思路,为开发高疗效、高质量、高标准的治疗方法和治疗药物奠定了基础。
Objective:The knee osteoarthritis is a common and frequently-occurring disease of quinquagenarian.It is has become one of the global public health problem, which are caused the arthritis and complication have seriously influenced the old people's quality of life. The Knee osteoarthritis effective prevention and treatment has become the urgent matter. This study based on the tenet of scientific research and serving the society, and finding out a safe, convenient and continuous effective approach for the knee osteoarthritis treatment.
Methods:Put the 60 cases of the knee osteoarthritis patients that according with the criteria, randomly divided into two groups, each group of 30 cases, the treatment group gives the apply cointment Tazi of the Chinese medicine treatment, the control group gives the TDP (specialized electromagnetic wave) therapeutic apparatus the radiation therapy. And put a grade for the on admission and the clinical symptoms of after treatment , which separately according to“Chinese herbal medicine clinical research guiding principle”standard. the income data will be statistical analysed by spssl2. 0 statistical software and impersonal appraise the two therapy method of clinical therapeutic effect.
Results:The total effective rate of the treatment group is 90.00%, and the control effective rate of the treatment group is 76.67%. The curative effect of treatment group was obviously higher than that of the control group (P < 0.05).
Conclusion:The therapeutic effect is remarkable for the knee osteoarthritis of the Chinese medicine Tazi treatment, worth clinical extending. Confirmed the effectiveness of the Chinese medicine Tazi treatment and broadened the ideas of the knee osteoarthritis treatment, for developing the high curative effect, high quality, high standard treatments and drug therapy laid a foundation.
方法:将符合纳入标准的60例膝骨性关节炎患者,按随机原则分为治疗组和对照组,每组30例,治疗组给予中药溻渍外敷治疗,对照组给予TDP(特定电磁波)治疗仪照射治疗。并将治疗前、治疗后的临床症状分别根据《中药新药临床研究指导原则》的标准给予评分,将所得数据经spssl2. 0统计软件进行统计学分析,客观评价两种治疗方法的临床治疗效果。
结果:治疗组总有效率为90.00%,对照组总有效率为76.67%,治疗组疗效明显高于对照组(P<0.05)。
结论:中药溻渍治疗膝骨性关节炎的疗效显著,证实了中药溻渍治疗的有效性,拓宽了膝骨性关节炎的治疗思路,为开发高疗效、高质量、高标准的治疗方法和治疗药物奠定了基础。
Objective:The knee osteoarthritis is a common and frequently-occurring disease of quinquagenarian.It is has become one of the global public health problem, which are caused the arthritis and complication have seriously influenced the old people's quality of life. The Knee osteoarthritis effective prevention and treatment has become the urgent matter. This study based on the tenet of scientific research and serving the society, and finding out a safe, convenient and continuous effective approach for the knee osteoarthritis treatment.
Methods:Put the 60 cases of the knee osteoarthritis patients that according with the criteria, randomly divided into two groups, each group of 30 cases, the treatment group gives the apply cointment Tazi of the Chinese medicine treatment, the control group gives the TDP (specialized electromagnetic wave) therapeutic apparatus the radiation therapy. And put a grade for the on admission and the clinical symptoms of after treatment , which separately according to“Chinese herbal medicine clinical research guiding principle”standard. the income data will be statistical analysed by spssl2. 0 statistical software and impersonal appraise the two therapy method of clinical therapeutic effect.
Results:The total effective rate of the treatment group is 90.00%, and the control effective rate of the treatment group is 76.67%. The curative effect of treatment group was obviously higher than that of the control group (P < 0.05).
Conclusion:The therapeutic effect is remarkable for the knee osteoarthritis of the Chinese medicine Tazi treatment, worth clinical extending. Confirmed the effectiveness of the Chinese medicine Tazi treatment and broadened the ideas of the knee osteoarthritis treatment, for developing the high curative effect, high quality, high standard treatments and drug therapy laid a foundation.
引文
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[27]徐华明.推拿配合激光穴位照射治疗膝骨性关节炎[J].中医正骨.2004,16(11):42
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[30]范永军.三联疗法治疗膝骨性关节炎103例[J].中医研究,2009,22(10):46
[31]胥少汀,葛宝丰,徐印坎主编.实用骨科学[M].第三版.北京.人民军医出版社.2005:1338
[32]郑冰.中西医结合治疗膝骨性关节炎78例[J].福建中医药,2004,35(6):20
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[34]陈启明主编.骨科基础学[M].第2版.北京:人民卫生出版社,2002:416
[35]刘炯.骨内高压症的研究现状和进展[J].中国骨与关节损伤杂志,2008,23(4):350-352
[36] Moskowitz RW. The burden of osteoarthritisclin ical amd quality of life issues[J] .Am JM anag Care, 2009,(8)223-229
[37]帖泰,谭秋祥.现代综合疗法治疗膝骨性关节炎98例报. [J].中医正骨,2008,20(9):62
[38]江锋,陈巍,马川.膝骨性关节炎患者关节滑液肿瘤坏死因子表达及其临床意义[J].实用医学杂志,2010,26(2):246-247
[39] LinclowTE.Osteoarthritis:new insights[J].AnnInternMed, 2002,13(6):86-88
[40] Altman RD.Criterria for classification of clinical osteoa rthritis.[J] rheumatol,1991,18 (27):10-12
[41]张劲,丑刚,周俊,等.透明质酸钠注射配合千草方薰洗对膝骨关节骨性关节软骨的影响[ J] .中国中医骨伤科杂志,2009,17(14):35
[42]常彬,薛冬,彭丹.128例膝关节骨关节炎的治疗体会[J].长治医学院学报,2010,24(1):44-45.
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[2]徐卫东,吴岳富,张春才主编.骨关节炎的诊断与治疗[M].第2版.上海.第二军医大学出版社,2004:8,10,20
[3]黎立.痹祺胶囊治疗膝关节骨性关节炎的临床疗效观察中华中医药杂志(原中国医药学报),2009,24(4):492
[4]陈秋明,佘伯亮,宾淑芬.温针灸内外膝眼穴为主治疗膝骨性关节炎[J].针灸临床杂志.2008,24(4):9-10.
[5]李西海,梁文娜,刘献祥.从痰瘀论治膝骨性关节炎50例临床观察[J].中医杂志,2009,50(2):136-138
[6]郭建刚,冯坤,赵仪.中药内服治疗骨性关节炎新进展[J].中医正骨,2002,14(4):54
[7]任超西,赵明山.辨证论治退行性膝关节骨性关节病[J].河南中医学院学报,2004,19(113):55
[8]马明明.中医辨证治疗中老年膝关节骨性关节炎98例[J].河北中医,2002,24 (2):107-108
[9]叶芳,叶肯华,叶欣.辨证施治膝骨性关节炎81例[J].陕西中医,2005,26(12):1302-1303
[10]陈泽文,喻友军.骨痹汤治疗膝关节骨性关节炎82例总结[J].湖南中医杂志,2002,18(3):22-23
[11]黄少江.补阳还五汤加味治疗老年膝关节性关节病疗效观察[J].中华实用中西医杂志2005 VOL.(18) NO.10 1508
[12]谢心军.加味思仙续断方治疗膝关节骨关节炎疗效观察[J].中医正骨,2005,17 (7):13-14.
[13]王培民,夏岩,许建安.膝宁方治疗膝关节骨性关节炎平地行走疼痛的临床观察[J].中医骨伤,2005,18(4):240-241
[14]曹向阳,李无阳,郭艳锦.壮筋活血汤治疗膝骨关节炎152例[J].上海中医杂志,2004,38(6):30-31
[15]杜世华.温经活血汤治疗膝骨性关节炎89例[J].山东中医杂志,2007,2(6): 390
[16]彭宇,袁长深.中医外治法治疗膝骨性关节炎近况[J].现代中医药,2008,28(2):58
[17]李孟,徐鹏飞,朱长庚.八味膏治疗膝骨性关节炎80例[J].陕西中医2009,30(8):1007
[18]宋晓平,孙智平.舒筋活络洗剂治疗膝骨性关节炎41例[J].现代中医药2009,29(5):30
[19]李彦丽、崔书国、赵建改良中药外洗法治疗膝骨性关节炎的疗效观察[J].河北中医2009,31(8):1150
[20]李刚,贾胜洪.中药熏药加外敷治疗膝骨性关节炎32例[J].杏林中医药2009,29(8):685
[21]何勇,徐阳平,霍雄涛.艾灸治疗膝关节骨性关节炎的临床研究[J].中国中医骨伤杂志,2009, 17( 3): 38-39
[22]刘玲玲.循经穴位注射加艾条灸治疗膝骨骨性节炎[J].临床观察中医药导报,2009,15(9):35
[23]陈鸣,高伟.采用针刺配合电针治疗膝骨性关节炎80例[J].Journal of External Therapy of TCM Oct,2009,18(5):44
[24]丁开玺.膝关节骨性关节炎的保守治疗[J].河北医学,2004,10(6):555-556
[25]张石鹏.中药熏蒸配合推拿手法治疗膝骨性关节炎86例[J].民间疗法,2008,12:20-21.
[26]王秀清.直流电中药离子导入治疗膝关节骨性关节炎68例[J].中国疗养学,2004,13(4)203-204
[27]徐华明.推拿配合激光穴位照射治疗膝骨性关节炎[J].中医正骨.2004,16(11):42
[28]邓小川,陈洪波,郭帮富.熏洗弹拨练功三联法对兔膝OA软骨细胞凋亡影响的实验研究[J].中国中医骨伤杂志.2009,17(8):4-7.
[29]谢添,董晓俊,章汉平.四联疗法治疗膝关节骨性关节炎[J].湖北中医杂志,2009,31(l):45
[30]范永军.三联疗法治疗膝骨性关节炎103例[J].中医研究,2009,22(10):46
[31]胥少汀,葛宝丰,徐印坎主编.实用骨科学[M].第三版.北京.人民军医出版社.2005:1338
[32]郑冰.中西医结合治疗膝骨性关节炎78例[J].福建中医药,2004,35(6):20
[33] Felson DT. Preventing knee and hip osteoarthritis.Bull Rheum Dis,1998. 47:1-4
[34]陈启明主编.骨科基础学[M].第2版.北京:人民卫生出版社,2002:416
[35]刘炯.骨内高压症的研究现状和进展[J].中国骨与关节损伤杂志,2008,23(4):350-352
[36] Moskowitz RW. The burden of osteoarthritisclin ical amd quality of life issues[J] .Am JM anag Care, 2009,(8)223-229
[37]帖泰,谭秋祥.现代综合疗法治疗膝骨性关节炎98例报. [J].中医正骨,2008,20(9):62
[38]江锋,陈巍,马川.膝骨性关节炎患者关节滑液肿瘤坏死因子表达及其临床意义[J].实用医学杂志,2010,26(2):246-247
[39] LinclowTE.Osteoarthritis:new insights[J].AnnInternMed, 2002,13(6):86-88
[40] Altman RD.Criterria for classification of clinical osteoa rthritis.[J] rheumatol,1991,18 (27):10-12
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