肛疾宁外洗颗粒用于混合痔术后的临床研究
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摘要
目的：探讨肛疾宁外洗颗粒防治混合痔术后主要并发症的临床疗效。方法：在符合纳入标准的病例中选择60例病人,随机分为观察组、对照一组、对照二组。三组病例在术后常规治疗的基础上,自术后第一天起观察组20人给予肛疾宁外洗颗粒熏洗;对照一组20人给予花子叶汤熏洗；对照二组20人仅给予温开水熏洗治疗。七天为一疗程,详细观察患者并发症情况,对其治疗第2d、5d、7d时的主要症状体征进行评价。结果：临床研究表明,在用药的第5d、7d观察组和两对照组在改善肛门疼痛、水肿、坠胀,便血方面有显著性差异(p<0.05)；在用药的2d观察组和两对照组在改善疼痛,坠胀,便血方面没有显著差异(p>0.05)；用药的第2d、5d、7d观察组和两对照组之间在改善肛门水肿方面分别存在差异(p<0.05)；用药的第2d、5d、7d观察组与二对照组在改善肉芽生长及创面愈合状况时无显著差异(p>0.05)结论：以清热解毒,消肿止痛,凉血止血,收敛止痒立法组成的肛疾宁外洗颗粒,可通过改善末梢循环,缓解括约肌痉挛,抗炎,镇痛,止血,消肿等作用减轻混合痔术后的肛门疼痛、坠胀、便血等症状,有效防治术后创面愈合缓慢的症状,说明对混合痔术后的病机认识是合理的,清热解毒、凉血止血、消肿止痛是治疗混合痔术后主要并发症的有效方法,本方是防治混合痔术后主要并发症的有效方剂。
Objective:to observe the therapeutic effect of Gang Jining granule on preventing and Treating postoperational complications of mixed Hemorrhoids.Methods:We choose 60 patients who are accord with the diagnosis standard and assigned them into three groups at random.20 patients who are the treatment groups are treated by taking Gang Jining granule from the first day after operation,20 patients who are the first control groups are treated by fumigating with Hua Ziye soup piles from the first day after operation too,20 patients who are the second control groups are treated only by fumigating with warm water.To compare the treatment between the three groups after the 2nd,5nd,7nd by computation the data of postoperative.Results:The result is different between the treatment groups and the next two groups at anus dropsy and straining of anorectum at the 2nd,5 nd,7nd. The result is different between the treatment groups and the next two groups at urinary disturbance at the 2nd,5nd,7nd. The result is different between the treatment groups and the next two groups at anus pain at the 5nd,7nd.There is no obvious difference between the treatment groups and the first control groups at promote faecal function and bleeding with faecal at the 2nd,4nd,7nd.Conclusion:Gang Jining granule can effectively improve and prevent the anus dropsy and straining of anorectum, urinary disturbance, anus pain, faecal function and bleeding with faecal by improving blood capillary, alleviating the convolution of sphincter,pain-relieving,reducing inflammation etc.So it is said that we are correct at the pathogenesis of post-operational complications of the mixed Hemorrhoids with damp and heat poured and the Gang Jining granule is effective.
Objective:to observe the therapeutic effect of Gang Jining granule on preventing and Treating postoperational complications of mixed Hemorrhoids.Methods:We choose 60 patients who are accord with the diagnosis standard and assigned them into three groups at random.20 patients who are the treatment groups are treated by taking Gang Jining granule from the first day after operation,20 patients who are the first control groups are treated by fumigating with Hua Ziye soup piles from the first day after operation too,20 patients who are the second control groups are treated only by fumigating with warm water.To compare the treatment between the three groups after the 2nd,5nd,7nd by computation the data of postoperative.Results:The result is different between the treatment groups and the next two groups at anus dropsy and straining of anorectum at the 2nd,5 nd,7nd. The result is different between the treatment groups and the next two groups at urinary disturbance at the 2nd,5nd,7nd. The result is different between the treatment groups and the next two groups at anus pain at the 5nd,7nd.There is no obvious difference between the treatment groups and the first control groups at promote faecal function and bleeding with faecal at the 2nd,4nd,7nd.Conclusion:Gang Jining granule can effectively improve and prevent the anus dropsy and straining of anorectum, urinary disturbance, anus pain, faecal function and bleeding with faecal by improving blood capillary, alleviating the convolution of sphincter,pain-relieving,reducing inflammation etc.So it is said that we are correct at the pathogenesis of post-operational complications of the mixed Hemorrhoids with damp and heat poured and the Gang Jining granule is effective.
引文
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[2]朱东升,谢庆军.中药熏洗治疗肛肠病术后193例疗效观察[J].中华当代医学,2006,4(2)：68.
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[5]张俊峰,何东宏.双黄连注射液用于肛肠病术后创面换药178例[J].中国肛肠病杂志,2004,3(24)：41.
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[3]席子明,张永水.化痔丸化水熏泡治疗痔术后肛缘水肿136例[J].河南大学学报(医学版),2003,3(2)：54.
[4]周华.混合痔术后中药煎剂熏洗临床观察[J].浙江中西医结合杂志,2001,11(11)：705-706.
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[7]郭淳.痔洗一号液在肛肠病术后的应用观察[J].江西中医,2007,38(294)：55.
[8]周健,周泠,秦建平.肤痔清软膏在混合痔剥扎术后创面的应用[J].遵义医学院学报,2007,30(1)：38.
[9]程刚.复方珠黄霜在肛门术后创面的临床应用[J].辽宁医学杂志,2006,20(6)：372.
[10]吴艳,邢程.熊胆痔灵膏促进痔术后愈合的疗效观察[J].黑龙江医药科学,2002,25(2)：93.
[11]臧玲玲.黄秦软膏治疗痔瘘术后水肿[J].实用医技杂志,2006,13(3)：391.
[12]牟奇蓉.黄连膏加冰片外敷治疗混合痔术后水肿86例[J].中医外治杂志,2007,16(1)：22.
[13]魏红沁,丁春华,李艳芬,郁惠峰.针刺对混合痔剥扎术后镇痛的临床观察[J].上海针灸杂志,2007,(5)：186.
[14]温跃明.电针治疗肛肠病术后急性尿潴留93例[J].新中医,1998,30(4)：28-29.
[15]张金恩.复方薄荷脑注射液在肛肠病术后应用分析[M].大肠肛门病论文汇编,2001：297.
[16]曹天顺.中药超前平衡镇痛法对痔术后镇痛与并发症影响的临床研究[J].中国肛肠病杂志,2006,26(11)：40.
[17]朱健平,王宗锐,吴宋夏.龙脑促进药物经皮渗透作用的研究[J].中国药学杂志,1999,34(2)：104-106.
[18]王晖,许卫铭,王宗锐等.薄荷醇与冰片的促透作用中草药,1997,28(2)：93-95.
[19]魏莉,蔡贞贞,徐莲英.当归及其复方透皮吸收特性的研究[J].中国中药杂志,2000,25(1)：32-34.
[20]许碧莲,王晖,许卫铭等.冰片对盐酸川芎嗪促透作用的研究中成药,2001,23(12)：864-867.
[21]赵晓洋,竭福,葛荣明等.冰片抗真菌作用的超微结构观察[J].哈尔滨医科大学学报,1992,20(3)：295-297.
[22]常颂平,李玉春冰.片对真菌细胞超微结构的影响及治疗化脓性中耳炎的临床应用[J].中国中药杂志,2000,25(5)：306-308.
[23]刘莉莉,李晓玲.术后疼痛控制的护理现状[J].现代护理,2005,11(6)：441-443.
[24]Hicks TJ. Ethical implications of pain management in a nursing home:Adi-scussion Nursing Ethics,2000,7(5):392-398.
[25]贾宝全,冷玉芳.腹部手术后病人硬膜外自控镇痛的临床观察[J].中华麻醉学杂志,2002,22(6)：343.
[26]向峰.第十一次全国中西医结合大肠肛门病学术会议论文汇编,2006：96.
[27]王志伟,李江等.TDP特定电磁波肛部理疗对环状混合痔患者术后恢复的作用[J].华南国防医学杂志,2006,(20)5：45.
[28]武梅,潘小娅.太宁栓并TDP照射在混合痔术后的应用[J].现代中西医结合杂志,2006,15(9)：1173.
[29]徐照秀,蔡而玮.混合痔术后微波治疗30例疗效观察[J].河南中医,2006,(26)5：53.
[1]魏红沁,丁春华,李艳芬,郁惠峰.针刺对混合痔剥扎术后镇痛的临床观察[J].上海针灸杂志,2007,(5)：186.
[2]朱东升,谢庆军.中药熏洗治疗肛肠病术后193例疗效观察[J].中华当代医学,2006,4(2)：68.
[3]席子明,张永水.化痔丸化水熏泡治疗痔术后肛缘水肿136例[J].河南大学学报(医学版),23(2),54.
[4]刘剑,范金萍.肛肠病术后消炎止痛膏换药效果的临床观察[J].中国肛肠病杂志,2007,12(27)：49.
[5]张俊峰,何东宏.双黄连注射液用于肛肠病术后创面换药178例[J].中国肛肠病杂志,2004,3(24)：41.
[6]陈火根等.唬拍生肌膏在肛肠病术后换药中的应用[J].中国肛肠病杂志,2007,11(27)：54.
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