摘要
固相微萃取技术(SPME)是一种无溶剂的样品前处理技术,作为SPME技术发展的一种类型,固态萃取搅拌棒技术(SBSE)由于其萃取相的体积比SPME的大50-250倍,在萃取过程中自身进行搅拌,提高了目标组分的富集倍数约10~2,降低了分析检测下限,适合痕量有机污染物的萃取分析。
设计了SBSE专用热解析器,解析器内衬管为石英管,用气相色谱进样口对样品传输线进行加热,使解析下来的样品无损失全部转移到色谱柱中,利用分析柱头固定相的溶质聚焦技术和程序升温,使色谱峰形对称,没有出现额外的峰展宽现象。而且解析完全,没有残留,使用寿命长,成本低,适配于各种类型的气样色谱进样口和检测器。
采用溶胶凝胶技术(Sol-gel)合成了SBSE萃取相,由于萃取相本身与其载体玻璃之间通过化学键结合,获得了耐高温和耐溶剂的特点,耐温达300oC,使用寿命大于50次。表面多孔结构增加了样品与萃取相之间的接触面积,加速传质过程,提高萃取效率。一次涂层可以获得30μm的涂层厚度,多次涂渍可以使涂层厚度加倍。合成的萃取相适合于多环芳烃和有机农药类物质的分析,与气相色谱(GC)配合检测限达到ng/L级。建立了复杂样品分析前处理方法——有机溶剂提取与SBSE相结合的方法。
利用Sol-gel包埋技术对不含溶胶凝胶活性的乙烯基二甲基聚硅氧烷进行包埋,合成Fiber-SPME萃取相,提出了Sol-gel包埋理论即在高温老化阶段乙烯基聚合成网与溶胶网络相互嵌套,使制得萃取相最高耐温达300oC,使用寿命在100次以上。
针对海量样品前处理所遇到的困难,提出了固态样品瓶萃取技术(VSPME),实现了海量样本的多点同时采集,同时并行处理,避免了样品采集后和运输过程中所引起的变化。实现了处理时间和过程与样品数量无关的技术。
Solid-phase microextraction (SPME) is a simple and effective adsorption and desorption technique, which eliminates the need for solvents. As a new type of SPME, stir bar sorptive extraction (SBSE) has about 50-250 times more extraction phase than that of conventional SPME, resulting increase of enrichment factor up to 102. The stir bar coated with extraction phase is also used to stir samples during extraction. The SBSE technique is suitable for extraction of trace amount of organic compounds in food and environmental samples.
A thermal desorption system (TDS), consist of a quartz liner and heaters, gas flow controllers, temperature control units, and a sample transfer line to the GC, was designed and evaluated. A 90 mm long stainless steel cylinder of 6.7mm I.D. and 12mm O.D. was used to hold the desorption liner and the transfer line. The transfer line was inserted directly through the injector septum into the GC pre-column about 20 cm deep. Desorption is complete and no carry-over is found. The device is compatible to all GC, and is robust and low cost.
A sol-gel coating method for the preparation of bars used in sorptive microextraction was described. The extraction phase poly(dimethysiloane) (PDMS) was partially crosslinked with the sol-gel network, and the most part was entangled within the network. The thickness of coating layer is about 30μm by one coating process. Thicker coating layer can be realized by multi-coating process. The improved coating technology shows good thermal stability up to 300°C.
Organophosphorus pesticides (OPPs) in vegetables were determined by stir
引文
1 汪尔康,21 世纪的分析化学, 科学出版社,1999.
2 C. L. Arthur, J. Pawliszyn, Solid phase microextraction with thermal desorption using fused silica optical fibers, Anal Chem, 1990, 62 :2145-2148.
3 D. Louch, S. Motlagh. J, Pawliszyn, Dynamics of organic compound extraction from water using liquid-coated fused silica fibers, Anal Chem, 1992,64: 1187-1199.
4 J. Ai, Solid phase microextraction for quantitative analysis in nonequilibrium situation, Anal Chem, 1997, 69:1230-1236.
5 J. Ai, Headspace solid-phase microextraction. Dynamatics and quantitative analysis before reaching apparition equilibrium, Anal Chem, 1997, 69:3260-3266.
6 J.Ai, Solid-phase microextraction in headspace analysis. Dynamics in non-steady-state mass transfer, Anal Chem, 1998, 70:4822-4826.
7 R. Eisert, K. Levsen, Development of a prototype system for quasi-continuous analysis of organic contaminants in surface or sewage water based on in-line coupling of SPME to GC, J Chromatogr A, 1996, 737:59-65.
8 R. Eisert, J. Pawliszyn, New trends in solid-phase microextraction, Critical Reviews in Anal Chem, 1997, 27:103-135.
9 J. Chen, J. Pawliszyn, Anal Chem, Solid Phase Microextraction Coupled to High-Performance Liquid Chromatography, 1995, 67:2530-2533.
10 H. Kataoka, Automated sample prepaation using in-tube solid-phase microextraction and its application-a review, Anal Bioanal Chem, 2002, 373:31-45.
11 G. J. Hans, H. G. Janssen, C. A. Crammers, Use of open-tubular trapping columns for on-line extraction-capillary gas chromatography of aqueous samples, J High Resolut Chromatogr, 1993, 16:413-418.
12 S. Blomberg, J. Rocrad, Improved thick film open tubular traps for the enrichment of volatile organic compounds from air and water, J High Resolut Chromatogr, 1990, 13:509-515.
13 B. V. Burger, M.J. Roux, Design of automated solid-phase microextraction fortrace analysis of organic compounds in aqueous samples, J Chromatogr A, 1997,776:293-303.
14 R. Eisert, J. Pawliszyn, Automated In-Tube Solid-Phase Microextraction Coupled to High-Performance Liquid Chromatography, Anal Chem, 1997, 69:3140-3174.
15 王涵文,毛细管柱内固相微萃取的研究及与毛细管气相色谱在线联用装置的研制及应用, 中国科学院研究生院博士学位论文。
16 H.W. Wang, W. M. Liu, Y. F. Guan, In-tube solid phase microextraction and on-line coupling with high-resolution GC, LC-GC Europe, 2004,17: 144-151.
17 Y. F.Guan. H. W. Wang, W. M. Liu, On-line coupling of in-tube solid phase microextraction to capillary gas chromatography for trace analysis of aqueous samples. 色谱, 2004,22:354-357.
18. E. Baltussen, P. Sandra, F. David, and C.A. Cramers, Stir bar sorptive extraction (SBSE), a novel extraction technique for aqueous samples: theory and principles, J Microcol Sep, 1999,11, 737-747.
19 H. A. Soini, K. E. Bruce, D. Wiesler, et al. Stir bar sorptive extraction: A new quantitative and comprehensive sampling technique for determination of chemical signal profiles from biological media. J Chem Eco, 31 (2): 377-392.
20 E. Baltussen, C.A. Cramers, P. Sandra. Sorptive sample preparation-a review. Anal Bioanal Chem, 2002, 373:3-22.
21 www.gerstel.de
22 P. Sandra, B. Tienpont, F. David, Multi-residue screening of pesticides in vegetables, fruits and baby food by stir bar sorptive extraction-thermal desorption-capillary gas chromatography-mass spectrometry, J Chromatogr A, 2003, 1000:299-399.
23 H. Lord, J. Pawliszyn, Evolution of solid-phase microextraction technology, J Chromatogr A, 2000, 855:163-193.
24 T. Goercki, M. Yu, Theory of analyte extraction by selected porous polymer SPME fibres, J. Pawliszyn, Analyst, 1999, 124:643-649.
25 J. Pawliszyn, Applications of solid phase microextraction. Cambridge (UK) : The royal society of chemistry, 1999.
26 H.L. Lord, J. Pawliszyn, Evolutionof solid-phase microextraction technology, J Chromatogr A, 2000,855: 445-455.
27 Z. Inoel, C. Helical Sorbent for fast sorption and desorption in solid-phase microextraction gas chromatographic analysis, Anal Chem, 2002, 74:5501-5506
28 张道宁,吴采樱,艾飞, 固相微萃取高分子涂层的研究, 色谱,1999, 17:10-13.
29 W. M. Liu, Y. Hu, J. H. Zhao, Y. Xu, Physically incorporated extraction phase of solid-phase microextraction by sol-gel method, J Chromatog A, 1102,37-43.
30 王翔如,严健,贾丽,胡广林,陈曦,固相微萃取与色谱质谱联用快速监测水中萘与硝基萘, 分析化学,1998, 26: 133-136.
31 刘红河,黎源倩,孙成均, 顶空固相微萃取-气相色谱法测定酒中甲醇和杂醇油, 色谱,2002, 20:90-93.
32 P. Popp, A. Paschke, Efficiency of direct solid phase microextraction from water-comparison of diferent fibre type including a new C8-coating. Chromatogr, 1999, 49: 686-690.
33 M. Ligor, M. Scibiorek, B. Buszewski, New coating surfaces of fibers for solid phase microextraction, Microcolumn Sep, 1999, 11: 377-383.
34 L. Magdalena, B. Boguslaw, Determination of menthol and menthone in food and pharmaceutical products by solid phase microextraction-gas chromatograpy, J Chromatogr A, 1999, 847: 161-169.
35 Y. Liu, S. Feng, M. L. Lee, Solid-phase microextraction of PAHs from aqueous samples using fibers coated with HPLC chemically bonded silica stationary phases, Anal Chem, 1997, 69:5001-5005.
36 D. H. Wang, J. Xing, J. G. Peng, C.Y. Wu, Novel benzo-15-crown-5 sol-gel coating for solid-phase microextraction, J Chromatogr A, 2003, 1005:1-12.
37 仇文丽 曾昭睿, 用溶胶-凝胶法制备PEG-20M固相微萃取探头, 分析科学学报 ,2001,6:198-202.
38 Z. Zeng, W. Qui, Solid-phase mixroextraction using fused-silica fibers coated with sol-gel derived hydroxy-crown ether, Anal Chem, 2001, 73:2429
39 J. Y. Brian, R. T. Khalid, Electrochemical control of solid phase micro-extraction: conducting polymer coated film material applicable for preconcentration/analysis of neutral species, Talanta, 2002, 58:739-745.
40 J. C. Wu, H. Lord, Pawliszyn J, etal., Polypyrrole-coated capillary in-tube solid phase microextraction coupled with liquid chromatography-electrospray ionization mass spectrometry for the determination of β-blockers in urine and serum samples, J microcol Sep, 2000, 12:255.
41 J. C. Wu, X. M. Yu, Solid phase microextraction of inorganic anions based on ploypyrrole film, Analyst, 2000, 125:391-394.
42 J. L. Liao, C. M. Zeng, S. Hjerten, Solid phase micro extraction of biopolymers, exemplified with adsorption of basic proteins onto a fiber coated with polyacrylic acid, J Microcolumn Sep, 1996, 8:1-4.
43 T. Gorecki, P. Martos, J. Pawliszyn, Strategies for the analysis of polar solvents in liquid matrixes, Anal Chem, 1998, 70:19-27.
44 Y. Liu, Y. F. Shen, M. L. Lee, Porous layer solid phase microextraction using silica bonded phases, Anal Chem, 1997, 69:190-195.
45 Y. Liu, Y. F. Shen, A. Malik, Solid-phase microextraction of PAHs from aqueous samples using fibers coated with HPLC chemically bonded silica stationary phases, Anal Chem, 1997, 69:5001-5005.
46 T. P. Gbatu, K. L. Sutton, J. A. Caruso, Development of new SPME fibers by sol–gel technology for SPME-HPLC determination of organometals, Anal Chim Acta, 1999, 402:67-79.
47 韩素华,肖月华,吴采樱, 聚硅氧烷富勒烯固相微萃取涂层的性能,分析化学,2001,12,1374-1378.
48 J. X. Yu, L. Dong, C. Y. Wu, L. Wu, J. Xing, Hydroxyfullerene as novel coating for solid-phase microextraction fiber with sol-gel technology, J Chromatogr A, 2002, 978:37-48.
49 L. Cai, J. Xing, L. Dong, C. Wu, Application of polyphenylmethylsiloxane coated fiber for solid-phase microextraction combined with microwave-assisted extraction for the determination of organochlorine pesticides in Chinese teas, J Chromatogr A, 2003, 1015:11-21.
50 X. Li, Z. Zeng, J. Zhou, S. Gong, W, Wang, Y. Chen, Novel fiber coated with amide bridged-calix[4]arene used for solid-phase microextraction of aliphatic amines, J Chromatogr A, 2004, 1041: 1-9.
51 F. Zhou, X. Li, Z. Zeng, Determination of phenolic compounds in wastewater samples using a novel fiber by solid-phase microextraction coupled to gas chromatography, Anal Chim Acta, 2005. 538:63-70.
52 X. Li, Z. Zeng, S. Gao, H. Li, Preparation and characteristics of sol–gel-coated calix[4]arene fiber for solid-phase microextraction J Chromatogr A, 2004, 1023:15-25.
53 X. Li, Z. Zeng, J. Zhou, High thermal-stable sol-gel-coated calyx[4]arene fiber for solid-phase microextraction of chlorophenols, Anal Chim Acta, 2004, 509:27-37.
54 X. Li, Z. Zeng, J. Zhou, Y. Chen, Y. Xu, Determination of phthalate acid esters plasticizers in plastic by ultrasonic solvent extraction combined with solid-phase microextraction using calyx[4]arene fiber, Talanta, 2004, 63:1013-1019.
55 Y. Hu, Y. Yang, J. Huang, G. Li, Preparation and application of poly(dimethylsiloxane)/β-cyclodextrin solid-phase microextraction membrane, Anal Chim Acta, 2005, 543:17-24.
56 L. Wei, Q. Ou, J. Li, Preparation of a new fiber by sol-gel technology in solid-phase microextraction (SPME), Chin Chem Let, 2004, 15:1127-1130.
57 M. Azenha, C. Malheiro, A. F. Silva, Ultrathin phenyl-functionalized solid phase microextraction fiber coating developed by sol-gel deposition. J Chromatogr A, 2005, 1069:163-172.
58 M. Liu, Z. Zeng, B. Xiong, Preparation of novel solid-phase microextraction fibers by sol-gel technology for headspace solid-phase microextraction-gas chromatographyic analysis of aroma compounds in beer, J Chromatogr A, 2005, 1065:287-299.
59 K. Alhooshani, T. Y. Kim, A. Kabir, A. Malik, Sol-gel approach to in situ creation of high pH-resistant surface-bonded organic-inorganic hybrid zirconiacoating for capillary microextraction (in-tube SPME), J Chromatogr A,2005, 1062:1-14.
60 C. Basheer, S. Jegadesan, S. Valiyaveettil, H. k. Lee, Sol-gel-coated oligomers as novel stationary phases for solid-phase microextraction, J Chromatogr A, 2005, 1087:252-258.
61 M. Liu, Z. Zeng, H. Fang, Preparation and application of the sol-gel-derived acrylate/silicone co-polymer coatings for headspace solid-phase microextraction f 2-chlroethyl ethyl sulfide in soil, J Chromatogr A, 2005, 1076:16-26.
62 H. Fang, M. Liu, Z. Zeng, Solid-phase microextraction coupled with capillary electrophoresis to determine ephedrine derivatives in water and urine using a sol-gel derived butyl methacrylate/silicone fiber, J Chromatogr A, 2006, 1104: 359-365.
63 贾金平,冯雪,方能虎,黄加量, 活性碳纤维固相微芳取气相色谱-质谱联用测定水中苯系物.色谱,2002,20(1):63-65.
64 刘稷燕,江桂斌, 固相微萃取技术及其在有机锡和有机汞分析中的应用, 分析化学,1999, 27 (10): 1226-1230.
65 G. Jiang, J. Liu, Speciation analysis of butyltin compounds in Chinese seawater by capillary gas chromatography with flame photometric detection using in-situ hydride derivatization followed by headspace solid-phase microextraction, Anal Chim Acta, 2000, 421(1): 67-74.
66 D. Djozan, Y. Assadi, G. K. Nezhad. Modified copper wire as solid phase microextraction, Selective extraction of some amines, Chromatographia, 2002, 56(9-10):611-61.
67 方瑞斌,张维昊,陈章玉.石墨碳纤维基质的固相微萃取装置的研制及应用, 云南化工,1997, 4(1): 22-24.
68 方瑞斌,张维昊, 张馄玲. 新固相微萃取-气相色谱法分析大气中芳烃物质, 分析化学,1998, 26 (8): 1029-1032.
69 Djabanshir D, Yaaghoob A. Anodized Aluminum Wire as a Solid-Phase Microextraction Fiber, Anal Chem, 2001, 73:4054
70 Y. N. Gou, R. Eisert, J. Pawliszyn, Automated in-tube solid-phase microextraction high-performance liquid chromatography for carbamatepesticide analysis J Chromatogr A, 2000, 873:137-147.
71 C. Dietz, J. Sanz, C. Camara. Recent developments in solid-phase microextraction coatings and related techniques. J Chromatogr A, 2006, 1103:183-192.
72 J. C. Wu, J. Pawliszyn, Determination of stimulants in human urine and hair samples by polypyrrole coated capillary in-tube solid phase microextraction coupled with liquid chromatography-electrospray mass spectrometry Talanta, 2000, 54:655-672.
73 H. D. Gesser, P. C. Goswamii, Aerogels an related porous materials, Chem Rev, 1989, 89:765-788.
74 L. L. Hench, J. K.West, The sol-gel processs, Chem Rew, 1990, 90:33-72.
75 C. J. Brinker, G. W.Scherer, Sol-gel science-the physics and chemistry of sol-gel processing, Academic press, 1990, p2.
76 S. A. Rodriguez, L A Colon, Investigations of a sol–gel derived stationary phase for open tubular capillary electrochromatography, Anal Chim Acta 1999, 397, 207-215.
77 A.L. Crego, J.C. Diez-Masa, M.V. Dabrio, Preparation of open tubular columns for reversed-phase high-performance liquid chromatography, Anal Chem, 65 (1993) 1615-1621.
78 D. X. Wang, S. L. Chong, A. Malik, Sol-gel column technology for single-step deactivation, coating and stationary–phase immobilization in high-resolution capillary gas chromatography, Anal Chem, 1997, 69:4566-4576.
79 A. Malik, D. X. Wang, Solid-phase microextraction fiber structure and method of making, Patent NO. WO 00/17429.
80 S. L.Chong, D. Wang, J. D. Hayes, A. Malik, Sol-gel coating technology for the preparation of solid-phase microextraction fibers of enhanced thermal stability, Anal Chem, 1997, 69:3889-3898.
81 A. P. Vonderheide, M. Montes-Bayon, J. A. Caruso, Solid-phase microextraction as a sample prearation strategy for the analysis of seleno amino acids by gas chromatography-inductively coupled plasma mass spectrometry, Analyst, 2002, 127:49-53.
82 Zhaorui Z, Wenli Q, Ming Y, Xuan W, Zaifu H, Fang L. Solid-phase microextraction of monocyclic aromatic amines using novel fibers coated with crown ether, J Chromatogr A, 2001, 934(1-2): 51-57.
83 Zhaorui Z, Wenli Q, Zaifu H. Solid-phase microextraction using fused-silica fibers coated with sol-gel derived hydroxyl-crown ether, Anal Chem, 2001, 73(11):2429-2436.
84 L. Cai, Y ao, S. Gong, L. Gong, C. Wu, Use of a novel sol-gel dibenzo-18-crown-6 solid-phase microextraction fiber and a new derivatizing reagent for determination of aliphatic amines in lake water and human urine, Chromatographia, 2003, 58:615-621.
85 Z. Zeng, W. Qiu, H. Xing, Sol-gel-derived crown ether sationary phase for capillary gas chromatography, Anal Sci, 2000, 16:851-854.
86 Y. Lei, High extraction efficiency solid-phase microextraction fibers coated with open crown ether stationary phase using sol-gel technique, Anal Chim Acta, 2003, 486:63-72.
87 M. Liu, Z. Zeng, Y. Tian, Elimination of matrix effects for headspace solid-phase microextraction of important volatile compounds in red wine using a novel coating, Anal Chim Acta, 2005, 54:341-353.
88 M Yang, Z R Zeng, W L Qiu, Y L Wang, Preparation and investigation of polymethylphenylvinylsiloxane-coated solid-phase microextraction fibers using sol-gel technology. Chromatogr, 2002, 56(1-2): 73-80.
89 M. Yang,Y. Wang,Z. Zeng,Y. Zhou. Preparation and characteristics of new coatingfor solid-phase microextraction, 色谱,2002, (3):202-206.
90 Zhenyu W, Chuhua X, Caiying W, Huirnin H. High-performance polyethylene glycol-coated solid-phase microextraction fibers using sol-gel technology. J Chromatogr A, 2000, 893:157-168.
91. Zh R.Silva, F. Augusto, Highly porous solid-phase microextraction fiber coating based on poly(ethylene glycol)-modified ormosils synthesized by sol-gel technology, J Chromatogr A, 2005, 1072:7-12.
92 J. Yu, L. Dong, C. Wu, L. Wu, J. Xing, Hydroxyfullerene as a novel coating for solid phase microextraction fiber with sol-gel technology. J Chromatogr A,2002, 978:37-48.
93 Matthew G, Susan V O. Application of Low-temperature glassy carbon films in solid-phase microextraction. Anal Chem, 2001, 73(24): 5841-5851.
94 M. Liu, Z. Zeng, C. Wang, Y. Tan, H. Liu, Solid-phase microextraction of phosphate and methylphosphonate using novel fibers coated with a sol-gel-derived silicone-divinylbenzene co-polymer, Chromatographia, 2003, 58:597-605.
95 J. Yu, C. Wu, J. Xing, Development of new solid-phase microextraction fibers by sol-gel technology for the determination of organophosphorus pesticide multiresidues in food, J Chromagogr A, 2004, 1036:101-111.
96 M. Liu, Z. Zeng, H. Fang, Preparation and application of the sol-gel-derived acrylate/silicone co-polymer coatings for headspace solid-phase microextraction of 2-chloroethyl ethyl sulfide in soil, J Chromatogr A, 2005, 1076:16-26.
97 A. L. Lopes, F. Augusto, Preparation and characterization of polydimethylsiloxane/poly(vinylalcohol) coated solid phase microextraction fibers using sol-gel technology, J Chromatogr A, 2004, 1056: 13-19.
98 V. G. Zuin, A. L. Lopes, J. H. Yariwake, F. Augsto, Application of a novel sol-gel polydimethylsiloxane-poly(vinyl alcohol) solid-phase microextraction fiber for gas chromatographic determination of pesticide residues in herbal infusions, J Chromatogr A, 2004, 1056:21-26.
99 杨敏,曾昭睿,仇文丽,黄载福,用于固相微萃取的乙烯基开链冠醚复合涂层的研制,高等学校化学学报,2003, 24:615-617.
100 C. Dong, Z. Zeng, X. Li, Determination of organochlorine pesticides and their metabolites in radish after headspace solid-phase microextraction using calyx[4]arene fiber, Talanta, 2005, 66:721-727.
101 Y. Fan, Y. Feng, S. Da, Z. Wang, In-tube solid-phase microextraction using a –cyclodextrin coated capillary coupled to high performance liquid chromatography for determination of no-steroidal anti-inflammatory drugs in urine samples, Talanta, 2005, 65:111-117.
102 H. Bagheri, A. Es-haghi, M. Rouini, Sol-gel-based solid-phasemicroextraction and gas chromatography-mass spectrometry determination of dextromethorphan and dextrorphan in human plasma, J Chromatogr B, 2005, 818:147-157.
103 B. L. Wittkamp, Determination of BTEX Compounds in Water by Solid-Phase Microextraction and Raman Spectroscopy, Anal Chem 1995, 67:600-605.
104 C. R. Jia. Solid phase microextraction combined with HPLC for determination of metal ions using crown ether as selective extracting reagent, J Micro Sep, 1998, 10:167-173.
105 K. Det , Optimization of solid-phase microextraction conditions for determination of phenols, Anal Chem, 1994, 66:160-167.
106 M. Chai, Determination of volatile chlorinated hydrocarbons in air and water with solid-phase microextraction, Analyst, 1993,118:1501-1505.
107 J. Y. Horng, Determination of the semi-volatile compounds nitrobenzene, isophorone, 2,4-dinitrotoluene and 2,6-dinitrotoluene in water using solid-phase microextraction with a polydimethylsiloxane- coated fibre, J Chromatogr A, 1994, 678:313-318.
108 R. Eisert, Element-selective detection of pesticides by gas chromatography—atomic emission detection and solid-phase microextraction, J Chromatogr A, 1994, 683:175-183.
109 Y. Cai, Determination of methylmercury in fish and river water samples using in situ sodium tetraethylborate derivatization following by solid-phase microextraction and gas chromatography-mass spectrometry, J Chromatogr A, 1995, 696:113-122.
110 C. Rivassseau, Comparsion of on-line SPE-HPLC and SPME-GC for the analysis of micro-contaminates in water, Chromatographia, 1995, 41:462-470.
111 A. A. Boydboland, Solid-phase microextraction of nitrogen-containing herbicides, J Chromatogr A, 1995, 704:163-172.
112 T. Gorecki, Determination of Tetraethyllead and Inorganic Lead in Water by Solid Phase Microextraction/Gas Chromatography, Anal Chem, 1996, 68:3008-3014.
113 A. A. Boydboland, Solid-Phase Microextraction Coupled with High-Performance Liquid Chromatography for the Determination of Alkylphenol Ethoxylate Surfactants in Water, Anal Chem, 1996, 68:1521-1529.
114 R. C. Hale, Determination of coal tar and creosote constituents in the aquatic environment, J Chromatogr A, 1997, 774:79-95.
115 A. L. Nguyen, Separation and Determination of Polycyclic Aromatic Hydrocarbons by Solid Phase Microextraction/Cyclodextrin-Modified Capillary Electrophoresis, Anal Chem, 1997, 69:1726-1731.
116 L. Pan, Derivatization/Solid-Phase Microextraction: New Approach to Polar Analytes, Anal Chem, 1997, 69:196-205.
117 S. Abarshick, Trace Analysis of Explosives in Seawater Using Solid-Phase Microextraction and Gas Chromatography/Ion Trap Mass Spectrometry, Anal Chem, 1998, 70:3015-3020.
118 M. Llompart, Solid-Phase Microextraction and Headspace Solid-Phase Microextraction for the Determination of Polychlorinated Biphenyls in Water Samples, Anal Chem, 1998, 70:2510-2515.
119 Z. Y. Zhang, Analysis of organic compounds in environmental samples by headspace solid phase microextraction, HRC-Journal of high resolution chromatography , 1993, 16:689-692.
120 P. Popp, Application of solid-phase microextraction and gas chromatography with electron-capture and mass spectrometric detection for the determination of hexachlorocyclohexanes in soil solutions, J Chromatogr A, 1994, 687:133-140.
121 K. G. Furtone, A simple, inexpensive, rapid, sensitive and solventless technique for the analysis of accelerants in fire debris based on SPME, HRC-Journal of high resolution chromatography, 1995,18:625-629.
122 C. M. Barshick, Elemental and Organometallic Analyses of Soil Using Glow Discharge Mass Spectrometry and Gas Chromatography/Mass Spectrometry, Rap Communi Mass Spectr. 1996, 10:341-346.
123 A. A. Boydboland, Simultaneous determination of 60 pesticides in water using solid-phase microextraction and gas chromatography–mass spectrometry, Aanalyst, 1996, 121:929-937.
124 K. J.Hageman, Coupled Subcritical Water Extraction with Solid-Phase Microextraction for Determining Semivolatile Organics in Environmental Solids, Anal Chem, 1996, 68:3892-3898.
125 K. J. Hangeman, Coupled Subcritical Water Extraction with Solid-Phase Microextraction for Determining Semivolatile Organics in Environmental Solids, Anal Chem, 1997, 69:801-801.
126 F. J. Santos, Analysis of chlorobenzenes in soils by headspace solid-phase microextraction and gas chromatography-ion trap mass spectrometry, J Chromatogr A, 1997, 771:181-189.
117 M. Moder, Characterization of water-soluble components of slurries using solid-phase microextraction coupled to liquid chromatography-mass spectrometry, J Micro Sep, 1998, 10:225-234.
128 M. R. Lee. Solid-phase microextraction and gas chromatography–mass spectrometry for determining chlorophenols from landfill leaches and soil, J Chromatogr A, 1998, 806:317-324.
129 T. J. Clark. Quantitative Determination of Phenols in Mainstream Smoke with Solid-Phase Microextraction–Gas Chromatography–Selected Ion Monitoring Mass Spectrometry , J Chromatographic Sci, 1996, 34:272-275.
130 M. Chai, Determination of volatile chlorinated hydrocarbons in air and water with solid-phase microextraction, Analyst, 1993, 118:1501-1505.
131 D. Gorlo, Calibration procedure for solid phase microextraction—gas chromatographic analysis of organic vapours in air, Talanta, 1997, 44:1543-1550.
132 M. Emccomb, Microextraction of volatile organic compounds using the inside needle capillary adsorption trap (INCAT) device, Talanta, 1997, 44:2137-2143.
133 P. Popp, Solid phase microextraction of volatile organic compounds using Carboxen-polydimethylsiloxane fibers, Chromatographia, 1997, 46:419-424.
134 P. Amartos. Estimation of Air/Coating Distribution Coefficients for Solid Phase Microextraction Using Retention Indexes from Linear Temperature-Programmed Capillary Gas Chromatography. Application to theSampling and Analysis of Total Petroleum Hydrocarbons in Air, Anal Chem, 1997, 69:402-408.
135 L. Pan, Derivatization/Solid-Phase Microextraction: New Approach to Polar Analytes, Anal Chem, 1997, 69:196-205.
136 S. B. Hawthorne, Solventless determination of caffeine in beverages using solid-phase microextraction with fused-silica fibers, J Chromatogr, 1992,603:185-191.
137 J. C. Wu, W. Xie, J. Pawliszyn, Automated in-tube solid phase microextraction coupled with HPLC-ES-MS for the determination of catechins and caffeine in tea. Analyst, 2000, 125: 2216-2222.
138 B. D. Page, Application of solid-phase microextraction to the headspace gas chromatographic analysis of halogenated volatiles in selected foods, J Chromatogr, 1993, 648:199-211.
139 A. J. Maich, Solid Phase Microextraction for Quantitative Headspace Sampling of Apple Volatiles, Anal Chem, 1996, 68:4114-4118.
140 H. Verhoeven, SPME: artifact formation and its avoidance, Chromatographia. 1997, 46:63-66.
141 T. J. Clark, Determination of Volatile Acids in Tobacco, Tea, and Coffee Using Derivatization–Purge and Trap Gas Chromatography–Selected Ion Monitoring Mass Spectrometry, J Chromatogr Sci, 1997, 35:209-212.
142 S. S. Yang, Determination of alkaloids using solid phase microtraction and GC-NPD, Chromatographia, 1998, 47:443-448.
143 D. D. L. C. Garcia. Analysis of Wine Bouquet Components Using Headspace Solid-Phase Microextraction-Capillary Gas Chromatography, J HRC-Journal of High Resolution Chromtography. 1998, 21:373-377.
144 M. M.estres, Headspace solid-phase microextraction analysis of volatile sulphides and disulphides in wine aroma, J Chromatogr A, 1998, 808:211-218.
145 N. P. Sen, Rapid semi-quantitative estimation of N-nitrosodibutylamine and N-nitrosodibenzylamine in smoked hams by solid-phase microextraction followed by gas chromatography-thermal energy analysis, J Chromatogr A, 1997, 788:131-140.
146 D. D. C. Garcia, Separation of metal cations in acidic solution by capillary electrophoresis with direct and indirect UV detection, HRC-Journal of High Resolution Chromtography, 1997, 20:665-668.
147 A. Keszler, Identification of Volatile Compounds in Sunflower Oil by Headspace SPME and Ion-Trap GC/MS, HRC-Journal of High Resolution Chromtography, 1998, 21:368-370.
148 Y. W. Wang, Solid phase microextraction associated with microwave assisted extraction of food products, HRC-Journal of High Resolution Chromtography, 1997, 20:213-216.
149 M. Chiarotti, Solid-phase microextraction (SPME) and gas-chromatographic analysis of anorectic compounds in human urine, J Microcol Sep, 1997, 9:249-252.
150 H.L. Lord, Method Optimization for the Analysis of Amphetamines in Urine by Solid-Phase Microextraction, Anal Chem, 1997, 69:3899-3906.
151 C. Battu, Screening Procedure for 21 Amphetamine-Related Compounds in Urine Using Solid-Phase Microextraction and Gas Chromatography–Mass Spectrometry, J Chromatogr Sci, 1998, 36:1-7.
152 M. Moder, Determination of urinary acylcarnitines by ESI-MS coupled with solid-phase microextraction (SPME), J. Mass. Sepctro. 1997, 32:1195-1204.
153 D. A. Volmer, Rapid determination of corticosteroids in urine by combined solid phase microextraction/liquid chromatography/mass spectrometry, Rapid Communications Mass Spectro. 1997, 11:1926-1934.
154 X. P. Lee, Detection of organophosphate pesticides in human bodyfluids by HS-SPME and capillary GC with nitrogen-phosphorates detection, Chromatographia. 1996, 42:135-140.
155 P. Okeyo, Analysis of steroids from human serum by SPME with headspace derivatization and GC/MS,HRC-Journal of High Resolution Chromtography, 1997, 20:171-173.
156 Y. Luo, Determination of five benzodiazepines in aqueous solution and biological fluids using solid-phase microextraction with Carbowax TM/DVB fiber coating, J Micro Sep, 1998, 10:193-201.
157 K. Takekawa, Analysis of cyanide in blood by headspace solid phase microextraction and gas chromatography. Chromatographia, 1998, 47:209-214.
158 L. S. Debruin, Solid-Phase Microextraction of Monocyclic Aromatic Amines from Biological Fluids, Anal Chem, 1998, 70:1986-1992.
159 B. J. Hall, Determination of Cannabinoids in Water and Human Saliva by Solid-Phase Microextraction and Quadrupole Ion Trap Gas Chromatography/Mass Spectrometry, Anal. Chem. 1998, 70:1788-1796.
160 C. Grote, Solid-Phase Microextraction for the Analysis of Human Breath, Anal Chem, 1997, 69:587-596.
161 Y. Cai, Determination of methylmercury in fish and river water samples using in situ sodium tetraethylborate derivatization following by solid-phase microextraction and gas chromatography-mass spectrometry, J Chromatogr A, 1995, 696(1):113-122.
162 C. Malosse, Solid-phase microextraction, an alternative method for the study of airborne insect pheromones (Metamasius hemipterus, coleoptera, curculionidae), HRC-Journal of High Resolution Chromtography, 1995, 18:669-670.
163 T. Gorecki, Pesticides by solid-phase microextraction. Results of a round robin test, Analyst, 1996, 121:1381-1386.
164 A. J. Matich, Solid Phase Microextraction for Quantitative Headspace Sampling of Apple Volatiles, Anal Chem, 1996, 68:4114-4118.
165 G. Moneti, Solid-phase Microextraction of Insect Epicuticular Hydrocarbons for Gas Chromatographic/Mass Spectrometric Analysis, Rapid communications in Mass Spectrometry, 1997, 11:857-862.
166 B. Frerot, Solid-phase microextraction (SPME): A new tool in pheromone identification in lepidoptera, HRC-Journal of High Resolution Chromtography, 1997, 20:340-342.
167 R. Maile, Sampling techniques for gas chromatographic–mass spectrometric analysis of long-chain free fatty acids from insect exocrine glands, J Chromatogr A, 1998, 816:169-175.
168 A. keszler, HRC-Journal of High Resolution Chromtography. Identificationof Volatile Compounds in Sunflower Oil by Headspace SPME and Ion-Trap GC/MS 1998, 21:368-370.
169 Y, Luo, Determination of five benzodiazepines in aqueous solution and biological fluids using solid-phase microextraction with carbowaxTM/DVB fiber coating, J Micro Sep, 1998, 10(2):193-201.
170 L. Nardi, Coupled in-tube SPME-HRGC:a complementary SPME technique to analyze aqueous samples by GC, Am Lab, 2002, 34:30-37.
171 B. C. Dennis, P. J. Marriott, H. K. Lee, P. D. Morrison, In-tube solid phase micro-extraction-gas chromatography of volatile compounds in aqueous solution, Analyst, 1999, 124:651-655.
172 B. Tienpont, F. David, T. Benijts, P. Sandra, Stir bar sorptive extraction-thermal desorption-capillary GC-MS for profiling and target component analysis of pharmaceutical drugs in urine, J Pharmaceutical and Biomedical Analysis, 2003, 32:569-579.
173 B. Tienpont, F. David, C. Bicchi, and P. Sandra, High capacity headspace sorptive extraction , J Microcol Sep, 2000, 12: 577-584.
174 B. Kolahgar, A. Hoffmann, and A.C. Heiden,“Evaluation of the Method of Stir Bar Sorptive Extraction for the Determination of Polycyclic Aromatic Hydrocarbons (PAH) in Water Samples,” paper M16, Proceedings of the 25th International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2002).
175 P. Popp, C. Bauer, and L. Weinrich, Application of a polysiloxane-based extraction method combined with column liquid chromatography to determine polycyclic aromatic hydrocarbons in environmental samples, Anal Chim Acta, 2004, 504:307-312.
176 P. Popp, C. Bauer, L. Weinrich, Application of a polysiloxane-based extraction method combined with column liquid chromatography to determine polycyclic aromatic hydrocarbons in environmental samples, Anal Chim Acta, 2001, 436:1-9.
177 N. Ochiai, K. Sasamoto, M. Takino, S.Yamashita, S. Daishima, A.C. Heiden, and A. Hoffmann, Determination of trace amounts of off-flavor compounds indrinking water by stir bar sorptive extraction and thermal desorption GC-MS, Analyst, 2001, 126:1652-1657.
178 D. Benanou, F. Acobas, M.R. de Roubin, F.David, and P. Sandra, Analysis of off-flavors in the aquatic environment by stir bar sorptive extraction-thermal desorption-capillary GC/MS/olfactormetry, Anal Bioanal Chem, 2003, 376:69-77.
179 J. Vercauteren, C. Pérèz, C. Devos, P. Sandra, F. Vanhaecke, and L. Moens, Stir bar sorptive extraction for the determination of ppq-level traces of organotin compounds in environmental samples with thermal desorption-capillary gas chromatography-ICP mass spectrometry, Anal Chem, 2001, 73:1509-1514.
180 B. Tienpont, F. David, and P. Sandra, Stir bar sorptive extraction-thermal desorption-capillary GC-MS applied to biological fluids, Anal Bioanal Chem, 2002,373:46-55.
181 H.G. Wahl, C. Peterfi, A. Hoffmann, and H.M. Liebich, “Analysis of Drugs in Human Body Fluids by Stir Bar Sorptive Extraction and Thermal Desorption GC/MS,” paper L15, Proceedings of the 23rd International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2000).
182 B. Tienpont, F. David, T. Benijts, P. Sandra, Stir bar sorptive extraction-thermal desorption-capillary GC-MS for profiling and target component analysis of pharmaceutical drugs in urine J Pharm Biomed Anal, 2003, 32:569-579.
183 H.G. Wahl, C. Peterfi, A. Hoffmann, and H.M. Liebich, “Analysis of Plasticizers and Their Metabolites in Body Fluids and Infusates by Stir Bar Sorptive Extraction and Thermal Desorption GC/MS,” paper D28, Proceedings of the 23rd International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2000).
184 H.A. Soini, K.E. Bruce, D. Wiesler, and M. Novotny, “Quantification of Volatiles in Mammalian Urine by Stir Bar Sorptive Extraction Techniques and Gas Chromatography,” paper D13, Proceedings of the 25th International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2002).
185 K. Desmet, P. Kiss, M. De Hertogh, and P. Sandra, “Analysis of Polycyclic Aromatic Hydrocarbon Metabolites in Urine Using in-situ Derivatisation Stir Bar Sorptive Extraction–CGC/MS,” paper D13, Proceedings of the 25th International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium,CD-ROM, 2002).
186 T. Benijts, J. Vercammen, R. Dams, H.P. Tuan, W. Lambert, and P. Sandra, Stir bar sorptive extraction–thermal desorption–capillary gas chromatography–mass spectrometry applied to the analysis of polychlorinated biphenyls in human sperm,J Chromatogr B, 2001, 755:137-142.
187 A.G.J. Tredoux, H.H. Lauer, T. Heideman, and P. Sandra, The Determination of Benzoic Acid in Lemon Flavored Beverages by Stir Bar Sorptive Extraction-CGC-MS J. High Resolut Chromatogr, 2000, 23, 644-646.
188 J.C.R. Demyttenaere, C. Dagher, R. Verhé, and P. Sandra, “Flavour Analysis of Greek White Wine Using Solid Phase Microextraction–Capillary GC/MS,” paper P35, Proceedings of the 25th International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2002).
189 A. Hoffmann and A.C. Heiden, “Determination of Flavor and Off Flavor Compounds in Dairy Products using Stir Bar Sorptive Extraction and Thermal Desorption GC/MSD/PFPD,” paper D34, Proceedings of the 23rd International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2000).
190 A. Hoffmann, A.C. Heiden, and E. P. fannkoch, “Flavor Profiling of Beverages by Stir Bar Sorptive Extraction and Thermal Desorption GC/MS/PFPD, Part II: Non-Alcoholic Beverages,” paper M33, Proceedings of the 23rd International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2000).
191 C. Bicchi, C. Cordero, C. Iori, P. Rubiolo, and P. Sandra, “Headspace Sorptive Extraction in the Headspace Analysis of Aromatic and Medicinal Plants,” paper D45, Proceedings of the 23rd International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2000).
192 P. Sandra, F. David, and J. Vercammen, Advances in Flavours and Fragrances, K.A.D. Swift, Ed. (Royal Society of Chemistry, Cambridge, United Kingdom, 2002), p. 27.
193 N. Ochiai, K. Sasamoto, M. Takino, S. Yamashita, S. Daishima, A.C. Heiden, and A. Hoffmann, Simultaneous determination of preservatives in beverages, vinegar, aqueous sauces, and quasi-drug drinks by stir-bar sorptive extraction (SBSE), Anal Bioanal Chem, 2002, 373:56-63.
194 A. Hoffmann, W.R. Sponholz, F. David, and P. Sandra, “Corkiness in Wine-Trace Analysis of 2,4,6-Trichloroanisole by Stir Bar Sorptive Extraction and Thermal Desorption GC/MS,” paper D35, Proceedings of the 23rd International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CDROM, 2000).
195 F. David, A. Tredoux, E. Baltussen, A. Hoffmann, and P. Sandra, “Determination of Contaminants in Wine Using Stir Bar Sorptive Extraction,” paper M35, Proceedings of the 23rd International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CDROM, 2000).
196 C. Bicchi, C. Cordero, C. Iori, P. Rubiolo, and P. Sandra, “Stir Bar Sorptive Extraction in Sample Preparation from Heterogeneous Matrices: Determination of Pesticide Residues in Pear Pulp at ppb Level,” paper D19, Proceedings of the 25th International Symposium on Capillary Chromatography (IOPMS, Kortrijk, Belgium, CD-ROM, 2002).
197 P. Sandra, B. Tienpont, J. Vercammen, A. Tredoux, T. Sandra, and F. David, Stir bar sorptive extraction applied to the determination of dicarboximide fungicides in wine, J Chromatogr A, 2001, 928:117-126.
198 P. Sandra, B. Tienpont, and F. David, Determination of the interconversion energy barrier of enantiomers by separation methods, J Chromatogr A, 2003, 1000, 779-800.
199 S. Nakamura, S. Daishima, Simultaneous determination of 64 pesticides in river water by stir bar sorptive extraction and thermal desorption-gas chromatography mass spectrometry, Anal Bioanal Chem, 2005, 382:99-107.
200 M. Kreck, A. Scharrer, S. Bilke, A. Mosandl, Stir bar sorptive extraction(SBSE)-enantio-MDGC-MS-a rapid method for the enantioselective analysis of chiral flavour compounds in strawberries, Eur Food Res Technol, 2001, 213:389-394.
201 M. Kawaguchi, K. Inoue, M. Yoshimura, H. Nakazawa, Determination of 4-nonylphenol and 4-tert.-oxtylphenol in water samples by stir bar sorptive extraction and thermal desertion-gas chromatography-mass spectrometry, Anal Bioanal Chem, 2004, 505:217-222.
202 P. Serodio, J. Nogueira, Multi-residue screening of endocrine disrupters chemicals in water samples by stir bar sorptive extraction-liquid desorption-capillary gas chromatography-mass spectrometry deterction, Anal Bioanal Chem, 2004, 517:21-32.
203 A. D. Villiers, G. Vanhoenacker, P. Sandra, Stir bar sorptive extraction-liquid desorption applied to the analysis of hop-derived bitter acids in beer by micellar electrokinetic chromatography, Electrophoresis, 2004, 25:664-669.
204 C. Bicchi, C. Iori, P. Rubiolo, P. Sandra, Headspace sorptive extraction (HSSE), stir bar sorptive extraction (SBSE), and solid phase microextraction (SPME) applied to the analysis of roasted Arabica coffee and coffee brew, J Agri Food Chem, 2002, 50:449-459.
205 S. Nakamura, N. Nakamura, S. Ito, Determination of 2-methylisoborneol and geosmin in water by gas chromatography-mass spectrometry using stir bar sorptive extraction, J Sep Sci 2001, 24:674-677.
206 N. Ochiai, K. Sasamoto, A. Hoffmann, Determination of stale-flavor carbonyl compounds in beer by stir bar soptive extraction with in-situ derivatization and thermal desorption-gas chromatography-mass spectrometry, J Chromatogr A, 2003, 986:101-110.
207 C. Blasco, M. Fernandez, Y. Pico, G. Font, Comparison of solid-phase microextraction and stir bar sorptive extraction for determining six organophosphorus insecticides in honey by liquid chromatography-mass spectrometry, J Chromatogr A, 2004, 1030:77-85.
208 M. Kawaguchi, K. Inoue, H. Nakazawa, Trace analysis of phenolid xenoestrogens in water samples by stir bar sorptive extraction with in situderivatizaion and thermal desorption-gas chromatography-mass spectrometry, J Chromatogr A, 2004, 1041:19-26.
209 A. Stopforth, A. Tredoux, A. Crouch, P. Sandra, A rapid method of diagnosing pulmonary tuberculsis using stir bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry, J Chromatogr A, 2004, 2005,1071:135-139.
210 J. Lambert, W. Mullett, E. Kwong, D. Lubda, Stir bar sorptive extraction based on restricted access material for the direct extraction of caffeine and metabolites in biological fluids, J Chromatogr A, 2005, 1075:43-49.
211 W. M. Liu, H.W. Wang, Y. F. Guan, Preparation of stir bars for sorptive extraction using sol-gel method, J Chromatogr A, 2004, 1045:15-22.
212 W. M. Liu, Y. Hu, J. H. Zhao, Y. Xu, Y. F. Guan, Determination of OPPs in potato and leek by stir bar sorptive extraction, J Chromatogr A, 2006, 1072:1-7.
1 L. Montero, P. Popp, A. Paschke, J. Pawliszyn, Polydimethylsiloxane rod extraction, a novel technique for the determination of organic micropollutants in water samples by thermal desorption-capillary gas chromatography-mass spectrometry, J Chromatogr A, 2004, 1025:17-26.
2 N. Ochiai, K. Sasamoto, M. Takino, S. Yamashita, S. Daishima, A. Hoffman, Determination of trace amounts of off-flavor compounds in drinking water by stir bar sorptive extraction and thermal desroption GC-MS, Analyst, 2001, 126:1652-1657.
3 Baltussen, E. Sandra, P. David, F. Cramers, C. Stir bar sorptive extraction (SBSE), a novel extraction technique for aqueous samples: theory and principles. J. Microcolumn separation, 1999, 11(10): 737-747.
4 周宁琳,有机硅聚合物导论,科学出版社,2002.
5辛松民,有机硅合成工艺及产品应用,化学工业出版社,1999.
6 刘国诠,余兆楼,色谱柱技术,化学工业出版社,2001.
7 R.W. Jones, Fundamental principles of sol-gel technology, North American publications center.
8 M. A. Jeannot, F. F.Cantwell, Solvent Microextraction into a Single Drop,Anal Chem, 1996,68: 2236-2240.
9 Ai. J, Solid-phase microextraction for quantitative analysis in nonequilibrium situations, Anal Chem, 1997, 69:1230-1236.
10 谢振伟,但德忠,赵燕,周娜,超声波辅助萃取技术在样品预处理中的应用,化学通报,2005,68:1-11.
1 H. Lord, J. Pawliszyn, Evolution of solid-phase microextraction technology, J Chromatogr A, 2000, 855:153-193.
2 H. G. Mol, H. G. Janssen, C. A. Crammers, Use of open-tubular trapping columns for on-line extraction-capillary gas chromatography of aqueous samples, J High Resolut Chromatogr, 1993, 16:413-418.
3 H.W. Wang, W. M. Liu, Y. F. Guan, In-tube solid phase microextraction and on-line coupling with high-resolution GC, LC-GC Europe, 2004,17 (3), 144-151.
4 关亚风,江涛,王涵文,一种填充毛细管液相色谱-高温气相色谱在线联用接口,中国专利,专利号:CN00252698.0。
5 P. Sandra, B. Tienpont, F. David, Multi-residue screening of pesticides in vegetables, fruits and baby gas chromatography-mass spectrometry, J Chromatogr A, 2003, 1000:299-309.
6 B. Kolahgar, A. Hoffmann, A. C. Heiden, Application of stir bar sorptive extraction to the determination of polycyclic aromatic hydrocarbons in aqueous samples, J Chromatogr A, 2002, 963:225-230.
7 www.gerstel.com/product.tdsg.htm.
1 T. Gorecki, R. Mindrup, J. Pawliszyn, Pesticides by solid-phase microextraction. Results of a round robin test, Analyst ,1996,121:1381-1386.
2 R. Ferrari, T. Nilsson, R. Arena, P. Arlati, G. Bartolucci, Inter-laboratory validation of solid-phase microextraction for the determination of triazine herbicides and their degradation products at ng/l level in water samples, J Chromatogr A 1998,795:371-376.
3 S. J. Crook, Presented at the 8th symposium on handling of environmental and biological samples in chromatogramphy, America, 1997.
4 F. Hernandez, J. Beltran, F. J. Lopez, J. V. Gaspar, Use of Solid-Phase Microextraction for the Quantitative Determination of Herbicides in Soil and Water Samples, Anal Chem, 2000,72:2313-2322.
5 L. Cai, J. Xing, L. Dong, C. Wu, Application of polyphonylmethylsiloxane coated fiber for solid-phase microextraction combined with microwave-assisted extraction for the determination of organochlorine pesticides in Chinese teas, J Chromatogr A, 2003,1015:11-21.
6 R. Hu, B. Hennion, L. Urruty, M. Montury, Food Addit Contam 1999,280:111.
7 A. A. Boyd-Boland, S. Magdic, J. Pawliszyn, Simultaneous determination of 60 pesticides in water using solid-phase microextraction and gas chromatography–mass spectrometry, Analyst, 1996, 121: 929-937.
8 A. A. Boyd-Boland, J. Pawliszyn, Solid-phase microextraction of nitrogen-containing herbicides, J Chromatogr A, 1995, 704:163-172.
9 M. Vitali, M. Guidotti, R. Giovinazzo, O. Cedrone, Food Addit Contam, 1998, 280: 280.
10 L. Urruty, M. Montury, M. Braci, J. Fournier, J. M.Dournel, Comparison of Two Recent Solventless Methods for the Determination of Procymidone Residues in Wines: SPME/GC/MS and ELISA Tests , J Agric Food Chem, 1997,45:1519-1522.
11 E.Pitarch, S.Egea, J. Beltran, F. J. Lopez, F. Hernandez, Presented at the 11thmeeting of Spanish society for analytical chemistry, Valencia, 1999.
12 A. Namera, M. Yashiki, N. Nagasawa, Y. Iwasaki, T. Kojima, Rapid analysis of malathion in blood using head space-solid phase microextraction and selected ion monitoring, Forensic Sci Int, 1997, 88:125-131.
13 X. P. Lee, T. Kumazawa, K. Sato, O. Suzuki, Detection of organophosphate pesticides in human body fluids by HS-SPME and capillary GC with nitrogen-phosphorates detection, Chromatographia, 1996, 42:135.
14 F. Guan, K. Watanabe, A. Ishii, H. Seno, T. Kumazawa, H. Hattori, O.Suzuki, J Chromatogr B, 1998, 71:205-211.
15 E. Manoli, C. Samara, Polycyclic aromatic hydrocarbons in natural waters:sources occurrence and analysis, Trends in Anal Chem, 1999, 18(6): 417~428.
16 E. Baltussen, H. G. Janssen, P. Sandra, C. A.Cramers, A novel type of liquid/liquid extraction for the preconcentration of organic micropollutants from aqueous samples: Applications to the analysis of PAH's and OCP's in water, J. High Resolut Chromatogr, 1997, 20(7):395~399.
17 E. R. Brouwer, A. N. J. Hermans, H. Lingeman, U. A. Brinkman, Determination of polycyclic aromatic hydrocarbons in surface water by column liquid chromatography with fluorescence detection, using on-line micelle-mediated sample preparation, J Chromatogr A, 1994, 669:45~47.
18 Y. He, H. K. Lee, Trace analysis by combined use of off-line solid-phase extraction, on-column sample focusing and U-shape flow cell in capillary liquid chromatography, J Chromatogr. A, 1998, 808:79~86.
19 H. Bagheri, A. Mohammadi, Pyrrole-based conductive polymer as the solid-phase extraction medium for the preconcentration of environmental pollutants in water samples followed by gas chromatography with flame ionization and mass spectrometry detection, J Chromatogr. A, 2003, 1015:23~30.
20 C. L. Arthur,Solid phase microextraction with thermal desorption using fusedsilica optical fibers, J. Pawliszyn, Anal Chem, 1990, 62:2145~2148.
21 D.S. Lough, S. Motlagh, J. Pawliszyn, Solid phase microextraction with thermal desorption using fused silica optical fibers, Anal. Chem. 1992, 64:1187~1199.
22 B Kolahgar, A. Hoffman, A. C. Heiden. Application of stir bar sorptive extraction to the determination of polycyclic aromatic hydrocarbons in aqueous samples, J Chromatogr A, 2002, 963:225-230.
23 J. Ai, Solid Phase Microextraction for Quantitative Analysis in Nonequilibrium Situations, Anal Chem, 1997, 69:1230~1236.
24 Z. Zhang, J. Huang, G. Yu, H. Hong, Occurrence of PAHs, PCBs and organochlorine pesticides in the Tonghui River of Beijing, China, Environ Pollut, 2004, 130: 249~261.
25 梁云爱, 孙光令, 分析试验室, 1994,13(5):47.
26 李志达, 陈振荣, 福州大学学报(自然科学版), 1994,22(6):116.
27 邱涤非, 肖晓瑶, 色谱, 1995,13(6):450.
28 丁明玉, 杨海军, 肖善强, 陈培榕, 色谱, 1999, 17(5):459~461.
1 H. Lord, J. Pawliszyn, Evolution of solid-phase microextraction technology, J Chromatography, 2000, 885:153-193.
2 A. Malik, D. Wang, Capillary column and method of making, World patent 2001 No. 2000011463.
3 D. Wang, S. L. Chong, A. Malik, Sol-gel column technology for single step deactivation , coating, and stationary-phase immobilization in high-resolution capillary gas chromatography, Anal Chem, 1997,69:4566-4576.
4 S. L. Chong, D. Wang, A. Malik, Sol-Gel Coating Technology for the Preparation of Solid-Phase Microextraction Fibers of Enhanced Thermal Stability, Anal Chem, 1997, 69:3889-3898.
5 C. Shende, A. Kabir, E. Townsend, A. Malik, Sol-gel poly(ethylene glycol) stationary phase for high-resolution capillary gas chromatography, Anal Chem, 2003, 75:3518-3530.
6 J. D. Hayes, A. Malik, Sol-gel open tubular ODS columns with reversed electroosmotic flow for capillary electrochromatography, Anal Chem, 2001, 73:987-996.
7 A. Malik, Advances in sol-gel based columns for capillary electrochromatography: sol-gel open-tubular columns, Electrophoresis, 2002, 23:3973-3992.
8 A. C. Pierre, G. M. Pajonk, Chemistry of aerogels and their applications, Chem Rev, 2002,102:4243-4265.
9 D. A. Loy, K. Shea, Bridged polysilsesquioxanes. Highly porous hybrid organic-inorganic materials, Chem Rev, 1995, 95:1434-1442.
10 Chen J, Pawliszyn J B. Solid Phase Microextraction Coupled to High-Performance Liquid Chromatography , Anal Chem, 1995,67(15):2530-2533.
11 Gou Y, Eiser R, Pawliszyn J. chromatography for carbamate pesticide analysisJ Chromatogr. A, 2000, 873(1):137-147.
12 Kataoka H, Narimatsu S, Lord H. Automated In-Tube Solid-Phase Microextraction Coupled with Liquid Chromatography/Electrospray Ionization Mass Spectrometry for the Determination of β-Blockers and Metabolites in Urine and Serum Samples,Anal Chem, 1999, 71(19):4237-4244.
13 Pawliszyn J, Ed, Applications of solid-phase microextraction. The Royal Society of Chemistry. Hertfordshire U. K. 1999
14 X. R. Xia, R. B.Leidy, Preparation and Characterization of Porous Silica-Coated Multifibers for Solid-Phase Microextraction,Anal. Chem. 2001, 73:2041-2047.
15 J. Vercaueren, C. Peres, C. Devos, P. Sandra. Stir Bar Sorptive Extraction for the Determination of ppq-Level Traces of Organotin Compounds in Environmental Samples with Thermal Desorption-Capillary Gas Chromatography-ICP Mass Spectrometry,Anal Chem. 2001, 73:1509-1514.
16 关亚风,刘文民,赵景红,王海龙 “一种固相萃取样品瓶和热解析装置”CN200410069204.7.