论肺络
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摘要
本文深入研究肺络理论,探讨肺络的实质,总结肺系络脉的生理特点及病理变化,肺络病的病因、病机、临床表现、治疗原则及治疗方药,分析肺络理论与难治性肺系疾病的相关性,从对因治疗及对络治疗两方面总结肺系疾病用药规律。建立肺络理论体系,为肺络相关性疾病的治疗提供新的思路和理论依据。
本研究立足研究中医学的传统方法,在大量检索古今文献的基础上,运用文献研究方法,对中医学“肺络”理论进行了系统梳理与研究,总结肺络的生理功能和病理变化,系统研究并建立“肺络病”的理论体系。运用内容分析法结合现代医学研究将肺络理论与难治性肺系疾病的相关性进行深入探讨,结合临床表现总结肺络相关性疾病的中医用药规律。
研究证实肺络的生物学本质,肺之络脉系统应包括肺血液循环、淋巴循环、气体交换系统及间质免疫系统,系调节气机与气化的重要场所,承载着肺之体、用的主要生物学内涵。各种难治性呼吸系统疾病如肺纤维化、慢阻肺、支气管扩张、肺癌、哮喘及过敏性鼻炎等疾病都属于肺络病范畴。这将有助于在中医整体辨治的基础上兼顾局部和微观辨治,有利于临床提高疗效。
This paper has researched the theory of lung collaterals deeply, Summarize the physiological characters and pathological changes of lung collaterals, discuss the reguar etiology and pathogenesis, clinical manifestations, treatment principle and common herbs of diseases of lung collaterals , prove that many difficult diseases of respiratory system belong to diseases of lung collaterals; make“dredgeing collaterals therapy”as the principle of diseases of lung collaterals, summarize the rules of treatment with herbs for lung’s diseases.
This study based on traditional methods of research onTCM, searched a large number of ancient and modern documents, applied the research methods of literature, systematicly summarized the physiological functionaries and pathological changes of lung collaterals, set up the theory system of diseases of lung collaterals. Using method of content analysis combined with modern medical research to discuss the relativity of difficulty diseases of respiratory system with theory of lung collaterals .summarized the treatment principles with herbs on the diseases of lung collaterals.
The study find that the essence of lung collaterals is that lung collaterals include the blood circulation system, lymph circulation system, gas exchange system and interstitial immune system of lung. The difficulty diseases of respiratory system such as Pulmonary Fibrosis, COPD, Bronchiectasia, Lung Cancer, Asthma and Allergic Rhinitis belong to diseases of lung collaterals. The discovery will help to give round consideration to both the overall differentiation and the locality or microcosmic differentiation, thereby it can help to enhance the clinical effectiveness.
本研究立足研究中医学的传统方法,在大量检索古今文献的基础上,运用文献研究方法,对中医学“肺络”理论进行了系统梳理与研究,总结肺络的生理功能和病理变化,系统研究并建立“肺络病”的理论体系。运用内容分析法结合现代医学研究将肺络理论与难治性肺系疾病的相关性进行深入探讨,结合临床表现总结肺络相关性疾病的中医用药规律。
研究证实肺络的生物学本质,肺之络脉系统应包括肺血液循环、淋巴循环、气体交换系统及间质免疫系统,系调节气机与气化的重要场所,承载着肺之体、用的主要生物学内涵。各种难治性呼吸系统疾病如肺纤维化、慢阻肺、支气管扩张、肺癌、哮喘及过敏性鼻炎等疾病都属于肺络病范畴。这将有助于在中医整体辨治的基础上兼顾局部和微观辨治,有利于临床提高疗效。
This paper has researched the theory of lung collaterals deeply, Summarize the physiological characters and pathological changes of lung collaterals, discuss the reguar etiology and pathogenesis, clinical manifestations, treatment principle and common herbs of diseases of lung collaterals , prove that many difficult diseases of respiratory system belong to diseases of lung collaterals; make“dredgeing collaterals therapy”as the principle of diseases of lung collaterals, summarize the rules of treatment with herbs for lung’s diseases.
This study based on traditional methods of research onTCM, searched a large number of ancient and modern documents, applied the research methods of literature, systematicly summarized the physiological functionaries and pathological changes of lung collaterals, set up the theory system of diseases of lung collaterals. Using method of content analysis combined with modern medical research to discuss the relativity of difficulty diseases of respiratory system with theory of lung collaterals .summarized the treatment principles with herbs on the diseases of lung collaterals.
The study find that the essence of lung collaterals is that lung collaterals include the blood circulation system, lymph circulation system, gas exchange system and interstitial immune system of lung. The difficulty diseases of respiratory system such as Pulmonary Fibrosis, COPD, Bronchiectasia, Lung Cancer, Asthma and Allergic Rhinitis belong to diseases of lung collaterals. The discovery will help to give round consideration to both the overall differentiation and the locality or microcosmic differentiation, thereby it can help to enhance the clinical effectiveness.
引文
[1]邱幸凡,陈刚.络脉的气血流注特点[J].天津中医药, 2003,20(4): 53
[2]吴以岭,贾振华.中医络病理论指导血管病变防治研究的思路探讨[J].第二军医大学学报, 2007; 28(7): 748-752
[3]陈金亮,杨晓黎.略论络病理论的形成与发展[J].中国中医药信息杂志, 2003; 10(10): 1-2
[4]张晓阳.论络病的临床辨治要点[J].辽宁中医杂志, 2001; 28(9):523-524
[5]邱幸凡.经络之气脉血脉两大系统探讨.湖北中医杂志,2006,28(3):22-24.
[6]姜萍.营卫与脉络关系探微[J].山东中医药大学学报,2005,29(6):431-432
[7]龚治芳.大鼠肺泡巨噬细胞的更新时间[J].中国应用生理学杂志,1988,4(3):234-237
[8]吴以岭.气络-NEI网络相关性探析[J].中医杂志,2005,16(10):723-726
[9]熊露,田少霞.肺癌络病的现代生物学机制研究[J].中国中医基础医学杂志, 2010,16(9):827
[10]陈灏珠.实用内科学[M].第11版.北京:人民卫生出版社,2001.16(22)
[11]吴攀华,黄日红,朱正奖.基质金属蛋白酶2-9组织抑制因子l在肺间质纤维化实脸中的表达[J].中华结核和吸杂志.2001,24(2):109-110
[12]宋建平.肺痹古今论.中华医史杂志,1998,28(4):212-215
[13]牛建昭,姜术霞,李或.多脏器纤维化的络病机制探讨.北京中医药大学学报,2004,27(6):4-6.
[14] Tomikl. A case of acute lupus pneumonitis follow by high-resolution CT'. Nippon Kyopy Shikkon Gakkai,1990,28(5) :786.
[15]陈灏珠,主编.实用内科学.第12版.北京:人民卫生出版社,200.1731-1732.
[16]文小平,张淑清,朱沈秋.气血学说与活血化瘀的临床应用[J].中医药信息,1998, (5):5.
[17]张天嵩,董洪涛,陈跃来.特发性肺纤维化的中医病机探讨[J].中医函授通讯,1999,18(3):14-15.
[18]张彦萍,曹书颖,马俊义,等.博莱霉素致肺纤维化大鼠凝血活性的变化及意义[J].中华结核和呼吸杂志,2005,28(8):541-544.
[19]中华医学会呼吸病学会慢性阻塞性肺疾病学组·慢性阻塞性肺疾病诊治指南[J].中华结核和呼吸杂志,2002,25(8):453.
[20] Fabbri LM, Hurd SS.GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of COPD:2003 updated(editorial) [J].Eur Respir J,2003,22(1):1-2
[21]翁心植.慢性阻塞性肺疾病与肺原性心脏病[M].北京:北京出版社,1999.29-41.
[22]王永炎,黄启福.论瘀毒阻络是络病形成的病理基础[J].北京中医药大学学报,1999,22(2):8.
[23]张霆.从络脉论治肺癌探讨[J].福建中医药,2007,38(1):48-49
[24]熊露,郑红刚.肺癌之络病观[J],中国中医基础医学杂志, 2007,13(2):86-90
[25]马作峰,王平,姜瑞雪,等.邱幸凡论治支气管哮喘的思路与方法[J].辽宁中医杂志,2006,33(12):1539-1540.
[26]余春晓,高鸿,朱月香,等.支气管激发试验在咳嗽变异性哮喘诊断中的作用[J].中国临床医生,2005,33(10):25-26.
[27]崔红生,杨保林,武维屏.哮病探析[J].中国医药学报,2000, 15(1): 60-61.
[28]王海娟,贾建勋.变应性鼻炎与支气管哮喘病机分析及同源疾病辨证治疗[J].甘肃中医,2009,22(2):47
[29]陈金亮,杨晓黎.略论络病理论的形成与发展[J].中国中医药信息杂志, 2003,10(10):1-2
[30]严道男.中医药治疗变应性鼻炎应兼顾辨病和辩证[J].江苏中医药,2007,39(2):1-2
[31]陈舒华,汪宗文,梅丽容.组胺激发试验对变应性鼻炎鼻粘膜微血管的影响[J].中国微循环, 2001,5(2):135
[1]牛建昭,姜术霞,李彧.多脏器纤维化的络病机制探讨[J].北京中医药大学学报,2004, 27(6):4
[2]王殿华.络病理论与肺纤维化关系的探讨[J].临床研究,2006,29(3)
[3]王步青,薛勤梅.肺络理论与肺纤维化关系探讨].探讨中国中医药信息杂志,2008, 15(11):93
[4]王魁亮,舒占钧,王坤玲.肺络痹辨治探析[J].理论研究,
[5]崔红生,邱冬梅,武维屏.肺间质纤维化从络病辨治思路[J].中国中医药报,2004, 6(3)
[6]李戎.论艾灸肺俞膏肓俞治疗肺纤维化的中医理论基础与施治依据[J].辽宁中医杂志,2001,31(4):291-293
[1]吴金峰,姜云香,杜娟.络病学说与慢性阻塞性肺疾病病机相关性探讨[J].山东中医药大学学报,2004,28(5):326
[2]宋俊生.试述中西医结合的切入点[J].辽宁中医杂志,2000,27(5):197.
[3]蒋宁,武维屏.中医络病学说与肺间质纤维化病机关系初探[J].中国中医基础医学杂志,2003,9(5):22.
[4]冯淬灵,武维屏.络病理论与慢性阻塞性肺疾病气道重塑[J].北京中医药大学学报,2003,26(4):75
[5]仕丽.温阳散寒化瘀通络法治疗慢性阻塞性肺疾病稳定期45例[J].深圳中西医结合杂志, 2 0 0 8, 18 (3):165
[6]唐光华,姜良铎,余如瑾.从“毒损肺络”说探讨慢性阻塞性肺病缓解期气道局部病机[J].中国中医药信息杂志,2006,13(1):88
[2]吴以岭,贾振华.中医络病理论指导血管病变防治研究的思路探讨[J].第二军医大学学报, 2007; 28(7): 748-752
[3]陈金亮,杨晓黎.略论络病理论的形成与发展[J].中国中医药信息杂志, 2003; 10(10): 1-2
[4]张晓阳.论络病的临床辨治要点[J].辽宁中医杂志, 2001; 28(9):523-524
[5]邱幸凡.经络之气脉血脉两大系统探讨.湖北中医杂志,2006,28(3):22-24.
[6]姜萍.营卫与脉络关系探微[J].山东中医药大学学报,2005,29(6):431-432
[7]龚治芳.大鼠肺泡巨噬细胞的更新时间[J].中国应用生理学杂志,1988,4(3):234-237
[8]吴以岭.气络-NEI网络相关性探析[J].中医杂志,2005,16(10):723-726
[9]熊露,田少霞.肺癌络病的现代生物学机制研究[J].中国中医基础医学杂志, 2010,16(9):827
[10]陈灏珠.实用内科学[M].第11版.北京:人民卫生出版社,2001.16(22)
[11]吴攀华,黄日红,朱正奖.基质金属蛋白酶2-9组织抑制因子l在肺间质纤维化实脸中的表达[J].中华结核和吸杂志.2001,24(2):109-110
[12]宋建平.肺痹古今论.中华医史杂志,1998,28(4):212-215
[13]牛建昭,姜术霞,李或.多脏器纤维化的络病机制探讨.北京中医药大学学报,2004,27(6):4-6.
[14] Tomikl. A case of acute lupus pneumonitis follow by high-resolution CT'. Nippon Kyopy Shikkon Gakkai,1990,28(5) :786.
[15]陈灏珠,主编.实用内科学.第12版.北京:人民卫生出版社,200.1731-1732.
[16]文小平,张淑清,朱沈秋.气血学说与活血化瘀的临床应用[J].中医药信息,1998, (5):5.
[17]张天嵩,董洪涛,陈跃来.特发性肺纤维化的中医病机探讨[J].中医函授通讯,1999,18(3):14-15.
[18]张彦萍,曹书颖,马俊义,等.博莱霉素致肺纤维化大鼠凝血活性的变化及意义[J].中华结核和呼吸杂志,2005,28(8):541-544.
[19]中华医学会呼吸病学会慢性阻塞性肺疾病学组·慢性阻塞性肺疾病诊治指南[J].中华结核和呼吸杂志,2002,25(8):453.
[20] Fabbri LM, Hurd SS.GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of COPD:2003 updated(editorial) [J].Eur Respir J,2003,22(1):1-2
[21]翁心植.慢性阻塞性肺疾病与肺原性心脏病[M].北京:北京出版社,1999.29-41.
[22]王永炎,黄启福.论瘀毒阻络是络病形成的病理基础[J].北京中医药大学学报,1999,22(2):8.
[23]张霆.从络脉论治肺癌探讨[J].福建中医药,2007,38(1):48-49
[24]熊露,郑红刚.肺癌之络病观[J],中国中医基础医学杂志, 2007,13(2):86-90
[25]马作峰,王平,姜瑞雪,等.邱幸凡论治支气管哮喘的思路与方法[J].辽宁中医杂志,2006,33(12):1539-1540.
[26]余春晓,高鸿,朱月香,等.支气管激发试验在咳嗽变异性哮喘诊断中的作用[J].中国临床医生,2005,33(10):25-26.
[27]崔红生,杨保林,武维屏.哮病探析[J].中国医药学报,2000, 15(1): 60-61.
[28]王海娟,贾建勋.变应性鼻炎与支气管哮喘病机分析及同源疾病辨证治疗[J].甘肃中医,2009,22(2):47
[29]陈金亮,杨晓黎.略论络病理论的形成与发展[J].中国中医药信息杂志, 2003,10(10):1-2
[30]严道男.中医药治疗变应性鼻炎应兼顾辨病和辩证[J].江苏中医药,2007,39(2):1-2
[31]陈舒华,汪宗文,梅丽容.组胺激发试验对变应性鼻炎鼻粘膜微血管的影响[J].中国微循环, 2001,5(2):135
[1]牛建昭,姜术霞,李彧.多脏器纤维化的络病机制探讨[J].北京中医药大学学报,2004, 27(6):4
[2]王殿华.络病理论与肺纤维化关系的探讨[J].临床研究,2006,29(3)
[3]王步青,薛勤梅.肺络理论与肺纤维化关系探讨].探讨中国中医药信息杂志,2008, 15(11):93
[4]王魁亮,舒占钧,王坤玲.肺络痹辨治探析[J].理论研究,
[5]崔红生,邱冬梅,武维屏.肺间质纤维化从络病辨治思路[J].中国中医药报,2004, 6(3)
[6]李戎.论艾灸肺俞膏肓俞治疗肺纤维化的中医理论基础与施治依据[J].辽宁中医杂志,2001,31(4):291-293
[1]吴金峰,姜云香,杜娟.络病学说与慢性阻塞性肺疾病病机相关性探讨[J].山东中医药大学学报,2004,28(5):326
[2]宋俊生.试述中西医结合的切入点[J].辽宁中医杂志,2000,27(5):197.
[3]蒋宁,武维屏.中医络病学说与肺间质纤维化病机关系初探[J].中国中医基础医学杂志,2003,9(5):22.
[4]冯淬灵,武维屏.络病理论与慢性阻塞性肺疾病气道重塑[J].北京中医药大学学报,2003,26(4):75
[5]仕丽.温阳散寒化瘀通络法治疗慢性阻塞性肺疾病稳定期45例[J].深圳中西医结合杂志, 2 0 0 8, 18 (3):165
[6]唐光华,姜良铎,余如瑾.从“毒损肺络”说探讨慢性阻塞性肺病缓解期气道局部病机[J].中国中医药信息杂志,2006,13(1):88