制药行业清洁生产指标体系的构建及清洁生产技术研究
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
制药行业通常被人们称为健康产业,与公众生活息息相关。近年来制药行业发展迅猛,但是在发展的同时也产生了一系列环境问题,其生产加工过程带来的废水、废气以及固体废物等环境污染已经成为阻碍行业发展、危害公众健康的主要问题
     在寻找经济和环境和谐统一的结合点上,美国、加拿大、英国等发达国家寻找到一条合适的途径,那就是清洁生产。清洁生产作为一种全新的可持续发展的思想,受到了世界各国的普遍认可和接受。清洁生产将全过程管理的环境战略持续的理念应用于生产过程、产品和服务中,以增加生态效益,减少对人类及环境的风险。在清洁生产方向的研究中,通过建立清洁生产指标体系可以对企业进行综合的生产全过程分析,评价企业实施清洁生产的水平,并针对企业存在的问题提出相应的清洁生产措施和管理制度,为企业持续开展清洁生产提供理论依据。
     本文在国内外清洁生产研究的基础上,以在制药行业中占有比重较大的大输液类作为研究对象,构建大输液类制药行业清洁生产评价指标体系。本文主要内容包含:
     (1)对大输液类制药行业各个环节可能产生的环境问题进行论述和分析,通过对国内外企业加工工艺和管理体系的系统研究以及对国内其他行业清洁生产评价指标体系的分析对比,从定性和定量的角度构建了包含资源和能源指标、污染物产生指标、资源综合利用指标、资源生态指标、生产工艺先进性指标、设备先进性指标、环境管理与劳动卫生指标、贯彻执行环保法规指标8个准则层31个指标层的大输液类制药行业清洁生产指标评价体系。
     (2)通过研究对比国内同行业企业先进指标,确定大输液类指标体系各指标的基准值。采用层次分析法并利用yaahp软件进行计算,确定所建立指标体系各指标的权重值并划分了相应的清洁生产水平等级。
     (3)以国内某制药企业为案例,运用建立的指标体系进行清洁生产水平评价,以此检验所建立指标体系与实际情况是否一致。结果表明,本文构建的指标体系和评价方法可操作性强、准确性较高,对我国制药行业清洁生产水平评价有一定的参考作用。
     (4)通过大量文献查阅和实地考察,本文归纳和总结了大输液类制药行业最佳可行清洁生产方案技术集成(BAT),为本行业其他企业实施清洁生产技术提供支持和参考。
The pharmaceutical industry is usually called healthy industry, and has many things to do with people's life. Recently, the pharmaceutical industry is developing rapidly, at the same time it produces a series of environmental problems. The waste water, exhaust and solid wastes produced in production process has become the hinder of the development of this industry and a public health hazard.
     In the search for harmony of economic growth and environment, the United States, Canada, Britain and other developed countries have found a suitable way which called cleaner production. Cleaner production as a brand new idea of sustainable development is now widely accepted by all countries in the world. It adopts the strategic concept of whole process of management into the production process, product and service in order to increases the ecological benefit and reduces the risk of human beings and the environment. In the research of cleaner production, the whole production process analysis of the enterprise and evaluation of enterprise implementation of cleaner production level is done by establishing a clean production index system. Corresponding clean production measures and management system are put forward which provides theoretical basis for the enterprise to carry out clean production.
     Based on the review of clean production, this paper takes the infusion as the research object for its large share in the pharmaceutical industry. Then, the evaluation index system of infusion is constructed. This article mainly includes:
     (1) The environmental problems caused by each link of the infusion of the pharmaceutical industry are discussed and analyzed in this paper. Through research on processing technology and management system of domestic and international enterprise and on cleaner production evaluation index system in other industries at home, the paper has built a infusion pharmaceutical industry clean production evaluation index system from the qualitative and quantitative point of view which contains resources and energy indicators, pollutants indicators, comprehensive utilization of resources indicators, ecological indicators, resource production technology advancement indicators, equipment advancement indicators, environment management and labor health indicators, implement environmental protection laws and regulations indicators. This index system includes 8 rule layers and 31 index levels.
     (2) Through the study of advanced index in domestic industry enterprise, the paper determined the basic value of the each index in the infusion index system. Weights of each index and levels of clean production is determined by using analytic hierarchy process and yaahp software
     (3) This paper takes a domestic pharmaceutical enterprise as a case, cleaner production level evaluation is done using the index system above, and the index system is examined with actual situation. The results show that the index system and evaluation method in this paper is feasible and highly accurate, and has reference function for the pharmaceutical industry clean production in China.
     (4) After a large number of literature review and investigation, this paper summed up the best feasible scheme of cleaner production technical integration (BAT) of the infusion in pharmaceutical industry, and also provides support and reference for cleaner production technology in other enterprise.
引文
[1]《制药工业水污染物排放标准—化学合成类》编制说明[S].2007.
    [2]国家经济贸易委员会.“十五”工业规划与发展战略[M].经济科学出版社,2001:96-106.
    [3]《制药行业水污染物排放标准—混装制剂类》编制说明[S].2007.
    [4]丁静,梁毅.制药企业药品生产过程中污染的控制咨询服务[J].化工装备技术,2006,15(7):55-60.
    [5]SUSAN L M, SAMUEL B M. Creating and managing a virtual inter-organizational learning network for greener production:a conceptual model and case study [J].Journal of Cleaner Production,2006,14:91-899.
    [6]BRUCE T. Encouraging industry to assess and implement cleaner production measures [J].Journal of Cleaner Production,2006(14):601-609.
    [7]SAMUEL B M, LARRY W A. Systems thinking and green chemistry in the textile industry:concepts, technologies and benefits [J].Journal of Cleaner Production,2004(12):585-601.
    [8]MUYS B, WOUTERS G, SPIRINCKX C. Cleaner production:a guide to information sources [J].Journal of Cleaner Production,1997:22-26.
    [9]ANASTAS P T, WILLAMSON T C. Green Chemistry:Frontiers in Benign Chemical Syntheses a Process New York:Oxford University Press [J].Journal of Cleaner Production,1998:33-39.
    [10]HILSON G. Barriers to implementing cleaner technologies and cleaner production practices in the mining industry:A case study of the Americas [J].Minerals Engineering,2000,13(7):699-717.
    [11]国际环境信息网[OL]. http://www.envirobiz.com.
    [12]National Productivity Council. From Waste to Profits, Guidelines for Waste Minimization [C].New Delhi,2004.
    [13]United Nations Environment Program, Industry and Environment, Cleaner Production Assessment Manual [J].New Delhi,2005.
    [14]DOWLER L. The Research University's Dilemma:Resource sharing and research in a institutional environment [J].Journal of Cleaner Production,1995,21:5-26.
    [15]技术服务和信息措施[OL].http://www.zghbxy.com/html/shengchan/20080504/440.html.
    [16]何炳光,王学军.国外清洁生产实施与启迪[M].2002,学苑出版社,北京.
    [17]中国21世纪议程——中国21世纪人口、环境与发展白皮书[M].中国环境科学出版社出版,1994,5:1-92.
    [18]刘敬禹.玻璃行业的清洁生产评价方法研究[D].长春:吉林大学,2006.
    [19]吴百力.推行清洁生产面临的问题及对策[J].环境保护科学,2000,(S1):7-8.
    [20]GRAEDEL T E, ALLENBY B R. Industrial Ecology [M].Englewood Cliffs. NJ:Prentice Hall,1995.
    [21]王福良.发展循环经济推行清洁生产[J].宁夏工程技术,2004,3(3):291-293.
    [22]NARAYANASWAMY V, SCOTT J A. Resource flow and product chain analysis as practical promote cleaner production initiatives [J].2003,11(2):375-387.
    [23]United States Environmental Protection Agency, Alternatives to chlorinated solvents for cleaning and degreasing [C].Toronto:University of Toronto Press,1994.
    [24]United States Environmental Protection Agency, Facility pollution prevention guide [C].Toronto:University of Toronto Press,1992.
    [25]彭庆彦等.清洁生产是控制环境污染的有效途径[J].北方环境,2004,6(29):22-35.
    [26]刘颖辉.“末端治理”和“清洁生产”[J].中国环保产业,2002,6:14-15.
    [27]刘青,吕航.末端治理和清洁生产的比较评述[J].环境污染与防治,2000,22:34-36.
    [28]乔致奇.实现环保与经济双赢的切入点是清洁生产与技术创新[J].北京:中国冶金,2001,5:56-69.
    [29]贾爱娟,靳敏.国内外清洁生产评价指标综述[J].陕西环境,2003,10(3):31-35.
    [30]周筝.国内外清洁生产进展现状综述[J].能源与环境,2007,(04):20-22.
    [31]王斌,陈建宏.矿山清洁生产评价体系研究[J].金属矿山,2007,(8):79-82.
    [32]Environmental Performance Indicators in Industry, Report 3,Draft Handbook, European Green Table, Norway[S].1993:22-36.
    [33]TADEUSZ F. An environment assessment method for cleaner production technologies [J].Journal of Cleaner Production,2007,15:914-919.
    [34]KOMENDAREK W. Enterprise certificate of purer production(in Polish) [J]. Czystsza Produkcja Polsee,1999,7:1-26.
    [35]ALLEN H. Environmental Indicators:A systematic approach to measuring and reporting on environmental politely performance in the center of sustainable development world resources institute [J].Journal of Cleaner Production,1995,5:28-36.
    [36]张平.清洁生产指标体系构建与案例数据库网站开发[D].上海:东华大学,2004.
    [37]JURGIS S. Cleaner production in the developing world [J].Clean Techno Environ Policy,2005,7:145-147.
    [38]魏宗华.工业企业清洁生产评估指标的研究[J].环境保护,2000,5:22-24.
    [39]孙彩霞.清洁生产审核评价方法研究与应用[D].浙江:浙江大学,2004.
    [40]李福平,吴自民,李良玉.水泥行业清洁生产评价方法初探[J].硅酸盐通报,2007,26(2):320-323.
    [41]刘英.清洁工艺过程及其关键技术的研究[D].重庆:重庆大学,2004.
    [42]李军,陈庄.产品生命周期评价体系探讨[J].重庆环境科学,1999,6:10-12.
    [43]白保柱,邓明,罗涛.清洁生产分析与评价实践[J].环境科学与技术,2001,5:36-39.
    [44]郝庆军.水泥工业清洁生产指标体系有关问题的研究[D].北京:北京工业大学,2007.
    [45]The Design for the Environment, U.S. Environmental Protection Agency(EPA) [OL].http://www.epa.gov/opptintr/dfe/.
    [46]KOMENDAREK W. Enterprise certificate of purer production(in Polish) [J] Clean Technologies and Environmental Policy,1995,(7):145-147.
    [47]宋之杰,高晓红.一种多指标综合评价中确定指标权重的方法[J].燕山大学学报,2002,(1):20-26.
    [48]宏成,闫玉静.综合评价中不可缺少的部分—权重的确定[J].科技论坛,2009,(3):58.
    [49]李祚泳.环境质量评价原理与方法.化学工业出版社,2004,33-36.
    [50]李立峰,张树深.清洁生产定量评价方法的研究与应用[J].化工装备技术.2003,(1):49-53.
    [51]刘轲,许冠英.清洁生产评价方法实证研究[J].中山大学学报论丛.2003,(1):110-113.
    [52]SAATY T L. The Analytic Hierarchy Process:Planning, Priority Setting, Resource Allocation [J].New York:McGraw Hill,1980:36-43.
    [53]WIND Y, SAATY T L. Marketing applications of the analytic hierarchy process [J].Management Science,1980(26):641-658.
    [54]田炯,王翠然,陆根法.层次分析法在生态效率评价中的应用研究[J].环境保护科学,2009,35(1):118-120.
    [55]王丽丽.模糊数学法结合层次分析法用于清洁生产潜力评估研究[D],重庆大学.
    [56]赵焕臣,许树柏.层次分析法:一种简易的新决策方法[M].北京,科学出版社,1986.
    [57]邓聚龙.灰色系统基本方法[M].湖北:华中理工大学出版社,1987.
    [58]孙昭文,杨俊行,李莉.层次分析法的判断矩阵一致性及其应用[J].天津大学学报,1994,27(4):487-492.
    [59]王守兰,武少华,焦倩.清洁生产评价方法——模糊数学法[J].北京工业大学学报,2005,(01):108-112.
    [60]吴云超,任蕾.国际工程承包项目风险评估——基于AHP的Yaahp软件实现[J].黑龙江对外经贸,2009(11):28-30.
    [61]电解金属锰行业清洁生产评价指标体系(试行),2002.
    [62]刘英.清洁工艺过程及其关键技术的研究[D].重庆大学,2004.
    [63]张平,陈东辉.清洁生产指标体系的评价模式探讨[J].污染防治技术,2004,17(1):107-108.
    [64]陈菁.矿山环评中值得关注的几个问题[J].有色冶金设计与研究,2008,29(2):36-37.
    [65]赵莹.食用植物油工业清洁生产综合评价方法研究[D].吉林:吉林大学,2007.
    [66]程燕.高岭土行业清洁生产评价指标体系构建[D].合肥:合肥工业大学,2009.
    [67]BARROS M C. Identification of best available techniques in the seafood industry:a case study [J].Journal of Cleaner Production,2008:1-9.
    [68]杨凯,丁峰,孙晶.制药企业节水途径及案例分析[J].污染防治技术,2003(3):36-39.
    [69]MIKKEL T, ESKILD H. Per Christensen. Cleaner production in Danish fish processing experiences, status and possible future strategies [J].Journal of Cleaner Production,2008:1-11.
    [70]张家坤.水力除灰系统的节水措施[J].华北电力技术,1994(8):25-26.
    [71]刘振铎,张东江.水平衡测试是做好节水工作的有效手段[J].河北水利水电技术,2002,(6):44.
    [72]宋勋.大输液水浴灭菌柜的节能降耗.医药工程设计[J],2007(1):2-6.
    [73]李杨果,王耀南,王威.基于机器视觉的大输液智能灯检机研究[J].光电工程,2006(3):35-42.
    [74]CHAN J P, PAIMER G. Machine vision-applications in industry [A].Application of Machine Vision.IEE Colloquium [C].London, UK:IEEE,1995.1/1-1/6.
    [75]THOMAS A,HOLT J. Real-time Industrial Visual Inspection:A Review [J]. Neurobiology of Learning and Memory,1995,1(2):139-158.
    [76]袁桂英.空白试验的相关因素对化学需氧量测定的影响[J].黑龙江科技信息,2010(8):42-52.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700