反复应用碘消毒剂可否导致人体过量摄碘的研究
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摘要
背景:以碘元素为有效成分的消毒剂在医学领域有着广泛的应用。外科医生在术前进行手部消毒时,含碘消毒剂一直是在世界范围内最经典的、应用最广的选择。碘元素同时是甲状腺激素的合成原料,碘的缺乏可引起多种甲状腺疾病。2001年以来,人们开始认识到,碘的摄入过量同样可使多种甲状腺疾病的发病率增加目的:探讨外科医生反复应用含碘消毒剂进行术前手部消毒是否会引起碘元素过量摄入。方法:使用国际公认的测定方法对上海中山医院长期使用安尔碘刷手的外科医生和器械护士的碘摄入水平进行测定,并在该医院使用新型消毒剂替换安尔碘之后对同样的样本再次进行了测定,作为自身对照。结果:经过对71例样本和61例对照样本的结果分析,发现该人群并不存在碘摄入过量,并且停用含碘消毒剂后该人群碘的摄入水平亦无显著下降。
Background: Disinfectants containing iodine are widely used in medicine field. It has been most commonly chosen by surgeons as the classic disinfectant for pre-operative scrub. Iodine is also a material for the thyroid gland to produce thyroid hormone, and the inadequate intake of iodine has been known to contribute to thyroid diseases. On the year 2001, it was known that the overdosed intake of iodine can also cause many kinds of thyroid diseases. Object: To determine whether repeated use of iodine as surgery scrub will causes overdosed intake of iodine. Methods: Determine the level of iodine intake of a group of surgeons and scrub nurses in Zhongshan Hospital who have been intensively using iodine as per-operative hand scrub, Then run the test again to the same group of people as a self-control after the hospital replaced the disinfectant with a new one without iodine, and contrast the results of the two times. Results: After analyzing the result from the specimen of 71 people and their self-control, it is believed that the intensive use of disinfectant with iodine does not cause overdosed iodine intake, and that after stop using it there is no significent decrease of the level of the iodine intake.
引文
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