塑料与纸质食品包装材料中抗氧化剂的测定及迁移研究
摘要
第一章：简述了食品及食品包装存在的问题、造成食品及食品包装材料安全问题的原因、各国因此制定的相关法律法规,以及有关食品包装材料中化学物的国内外研究进展,并在此基础上提出了本论文的研究内容及创新点。
第二章：对聚乙烯塑料食品包装材料中的抗氧化剂BHA、BHT、Irganox1076进行了研究,建立了一种快速、高效的快速溶剂萃取(ASE)-超高效液相色谱(UPLC)检测方法。并将本方法用于市售食品包装的实际检测。
第三章：建立了一种脂肪食品模拟物异辛烷中抗氧化剂BHA、BHT、Irganox1010、Irganox1076的旋转蒸发浓缩-UPLC检测方法。研究了聚乙烯(PE)膜中抗氧化剂向脂肪食品模拟物异辛烷的迁移,讨论了温度随时间对迁移的影响,根据迁移数据进行了初步的数学模型的建立,对实验值与数值模拟结果计算值作了对比分析。
第四章：利用MINTAB中心复合实验设计优化了抗氧化剂BPA、BHA、Ionox100、BHT、TTBP、AO425的UPLC检测方法,对比了脂肪食品模拟物橄榄油中以上6种抗氧化剂的旋涡振荡甲醇萃取-旋转蒸发净化浓缩以及乙酸乙酯：环己烷萃取-凝胶渗透色谱(GPC)净化浓缩提取方法,确定了最佳萃取溶剂、最小溶剂使用量。并将本方法用于实际食用油中抗氧化剂的检测。
第五章：建立了一种超声辅助丙酮萃取-超高效液相色谱-串联质谱联用(UPLC-MS/MS)检测纸质食品包装材料中的8种抗氧化剂BPA、BHA、Ionox100、BHT、TTBP、AO425、AO2246、AO300的方法。本着溶剂毒性越小越好、提取检测时间越短越好的原则,对比了不同溶剂的萃取效率、优化了液相洗脱梯度、确定了上机定容液,并考察了基质效应影响。
Chapter 1:The problems of food and food packages safety, the factors caused these problems, and the regulations related to food and food contact materials in different nations, as well as the advances in this field have been reviewed, on the basis of these reviews, our own research content and the creativity were put forward.
Chapter 2:A rapid method of extracting antioxidants BHA, BHT and Irganox1076 from PE film with methanol by accelerated solvent extraction (ASE) and determined by ultra performance liquid chromatography (UPLC) coupled with photodiode array (PDA) detector has been developed. The procedure developed has been applied to the determination of the antioxidants in different commercial food plastic packages.
Chapter 3:A rapid method of extracting antioxidants BHA, BHT, Irganox1010 and Irganox1076 from fatty food stimulant isooctane by evaporating and determining by UPLC coupled with PDA detector has been developed. The procedure developed has been applied to determine the migration of the four antioxidants from PE films into isooctane under different temperatures, mathematical modelling based on the data has been established, and comparison is made between experimental and numerical results.
Chapter 4:A confirmatory and sensitive UPLC procedure validated for determining antioxidants BPA, BHA, Ionox100, BHT, TTBP and AO425 has been optimized based on MINTAB statistical software. Agitation-centrifugation with methanol, concentrated by evaporating and agitation extraction with cyclohexane:ethyl acetate mixture clean up and concentration by gel permeation chromatography (GPC) has been compared. The best extraction solvent and the least volume has been confirmed. The procedure developed has been applied to determination of the antioxidants in different commercial oils.
Chapter 5:A confirmatory and sensitive method of ultrasonic-assisted extraction and UPLC-MS/MS determination for antioxidants BPA, BHA, Ionox100, BHT, TTBP, AO425, AO2246 and AO300 in paperboard used as food packages has been developed. On the principle of the smaller solvent toxicity and the shorter extraction time, different extraction solvents were compared. On the basis of the optimized gradient elution and confirmed solution for determination, matrix effect was evaluated.
第二章：对聚乙烯塑料食品包装材料中的抗氧化剂BHA、BHT、Irganox1076进行了研究,建立了一种快速、高效的快速溶剂萃取(ASE)-超高效液相色谱(UPLC)检测方法。并将本方法用于市售食品包装的实际检测。
第三章：建立了一种脂肪食品模拟物异辛烷中抗氧化剂BHA、BHT、Irganox1010、Irganox1076的旋转蒸发浓缩-UPLC检测方法。研究了聚乙烯(PE)膜中抗氧化剂向脂肪食品模拟物异辛烷的迁移,讨论了温度随时间对迁移的影响,根据迁移数据进行了初步的数学模型的建立,对实验值与数值模拟结果计算值作了对比分析。
第四章：利用MINTAB中心复合实验设计优化了抗氧化剂BPA、BHA、Ionox100、BHT、TTBP、AO425的UPLC检测方法,对比了脂肪食品模拟物橄榄油中以上6种抗氧化剂的旋涡振荡甲醇萃取-旋转蒸发净化浓缩以及乙酸乙酯：环己烷萃取-凝胶渗透色谱(GPC)净化浓缩提取方法,确定了最佳萃取溶剂、最小溶剂使用量。并将本方法用于实际食用油中抗氧化剂的检测。
第五章：建立了一种超声辅助丙酮萃取-超高效液相色谱-串联质谱联用(UPLC-MS/MS)检测纸质食品包装材料中的8种抗氧化剂BPA、BHA、Ionox100、BHT、TTBP、AO425、AO2246、AO300的方法。本着溶剂毒性越小越好、提取检测时间越短越好的原则,对比了不同溶剂的萃取效率、优化了液相洗脱梯度、确定了上机定容液,并考察了基质效应影响。
Chapter 1:The problems of food and food packages safety, the factors caused these problems, and the regulations related to food and food contact materials in different nations, as well as the advances in this field have been reviewed, on the basis of these reviews, our own research content and the creativity were put forward.
Chapter 2:A rapid method of extracting antioxidants BHA, BHT and Irganox1076 from PE film with methanol by accelerated solvent extraction (ASE) and determined by ultra performance liquid chromatography (UPLC) coupled with photodiode array (PDA) detector has been developed. The procedure developed has been applied to the determination of the antioxidants in different commercial food plastic packages.
Chapter 3:A rapid method of extracting antioxidants BHA, BHT, Irganox1010 and Irganox1076 from fatty food stimulant isooctane by evaporating and determining by UPLC coupled with PDA detector has been developed. The procedure developed has been applied to determine the migration of the four antioxidants from PE films into isooctane under different temperatures, mathematical modelling based on the data has been established, and comparison is made between experimental and numerical results.
Chapter 4:A confirmatory and sensitive UPLC procedure validated for determining antioxidants BPA, BHA, Ionox100, BHT, TTBP and AO425 has been optimized based on MINTAB statistical software. Agitation-centrifugation with methanol, concentrated by evaporating and agitation extraction with cyclohexane:ethyl acetate mixture clean up and concentration by gel permeation chromatography (GPC) has been compared. The best extraction solvent and the least volume has been confirmed. The procedure developed has been applied to determination of the antioxidants in different commercial oils.
Chapter 5:A confirmatory and sensitive method of ultrasonic-assisted extraction and UPLC-MS/MS determination for antioxidants BPA, BHA, Ionox100, BHT, TTBP, AO425, AO2246 and AO300 in paperboard used as food packages has been developed. On the principle of the smaller solvent toxicity and the shorter extraction time, different extraction solvents were compared. On the basis of the optimized gradient elution and confirmed solution for determination, matrix effect was evaluated.
引文
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[1]陈宇,王朝晖,郑德.实用塑料助剂手册.北京,化学工业出版社,2007：1
[2]Suman Michele, La Tegola Stefano, Catellani Dante. Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry Method for the Determination of Epoxidized Soybean Oil in Food Products. Journal of Agricultural and Food Chemistry.2005,53(26):9879-9884
[3]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Determination of antioxidant migration levels from low-density polyethylene films into food simulants. Journal of Chromatography A.2003,1018(1):53-62
[4]Jeon Dae Hoon, Park Gun Young, Kwak In Shin. Antioxidants and their migration into food simulants on irradiated LLDPE film. LWT-Food Science and Technology.2007, 40(1):151-156
[5]Alvaro Garrido-Lopez, Tena Maria Teresa. Experimental design approach for the optimisation of pressurised fluid extraction of additives from polyethylene films. Journal of Chromatography A.2005,1099(1-2):75-83
[6]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Antioxidant Content of and Migration from Commercial Polyethylene, Polypropylene, and Polyvinyl Chloride Packages. Journal of Agricultural and Food Chemistry.2007,55(8):3225-3231
[7]宋欢,李波,李波平.PVC塑料包装中化学物总迁移的研究.化学研究与应用.2009,21(6)：934-936
[8]韩兆让,卢爱玲.聚合物包装材料上单体分子的迁移.塑料包装.1996,6(1)：9-13
[9]Molander P., Haugland K., Hegna D. R. Determination of low levels of an antioxidant in polyolefins by large-volume injection temperature programmed packed capillary liquid chromatography. Journal of Chromatography A.1999,864(1):103-109
[10]Vandenburg Harold J., Clifford Anthony A., Bartle Keith D. Analytical Extraction of Additives From Polymers. The Analyst.1997,122:101R-115R
[11]李秀勇,牟峻,刘惠涛.超高效液相色谱-质谱法测定油脂中的10种抗氧化剂.分析化学.2008,36(3)：369-372
[12]刘宏程,黎其万,佴注.基质固相分散-HPLC法快速测定植物油中抗氧化剂.食品科学.2007,28(1)：253-255
[13]Noguerol-Cal Rosalia, Lopez-Vilarino Jose Manuel, Gonzalez-Rodriguez M. Victoria. Development of an ultraperformance liquid chromatography method for improved determination of additives in polymeric materials. Journal of Separation Science.2007, 30(15):2452-2459
[14]Camacho Walker, Karlsson Sigbritt. Quality-determination of recycled plastic packaging waste by identification of contaminants by GC-MS after microwave assisted extraction (MAE). Polymer Degradation and Stability.2000,71(1):123-134
[15]Minuti Lucio, Pellegrino Roberto. Determination of phenolic compounds in wines by novel matrix solid-phase dispersion extraction and gas chromatography/mass spectrometry. Journal of Chromatography A.2008,1185(1):23-30
[16]Commission Directive 2004/19/EC of 1 March 2004 amending Directive 2002/72/EC relating to plastic materials and articles intended to come into contact with foodstuffs.
[17]Commission Directive 2002/72/EC of 6 August 2002 relating to plastic materials and articles intended to come into contact with foodstuffs.218-220
[18]Council Directive 85/572/EEC of 19 December 1985 laying down the list of simulants to be used for testing migration of constituents of plastic materials and articles intended to come into contact with foodstuffs. L372/14-21
[1]Commission Directive 97/48/EC of 29 July 1997 amending for the second time Council Directive 82/711/EEC laying down the basic rules necessary for testing migration of the constituents of plastic materials and articles intended to come into contact with foodstuffs.
[2]Council Directive 85/572/EEC of 19 December 1985 laying down the list of simulants to be used for testing migration of constituents of plastic materials and articles intended to come into contact with foodstuffs.
[3]Helmroth Erika, Rijk Rinus, Dekker Matthijs. Predictive modelling of migration from packaging materials into food products for regulatory purposes. Trends in Food Science & Technology.2002,13(3):102-109
[4]Chung D., Papadakis S. E., Yam K. L. Simple models for assessing migration from food-packaging films. Food Additives & Contaminants.2002,19(6):611-617
[5]Begley T., Castle L., Feigenbaum A. Evaluation of migration models that might be used in support of regulations for food-contact plastics. Food Additives & Contaminants. 2005,22(1):73-90
[6]韩兆让,卢爱玲.聚合物包装材料上单体分子的迁移.塑料包装.1996,6(1)：9-13
[7]刘志刚,王志伟.塑料包装材料化学物向食品迁移的模型研究进展.高分子材料科学与工程.2007,23(5)：19-23
[8]王正林,刘志刚,胡长鹰.聚烯烃抗氧剂1076和168在食用油中的迁移研究.包装工程.2007,28(6)：1-3
[9]刘志刚,胡长鹰,王志伟.3种聚烯烃抗氧剂迁移的试验分析及数值模拟.包装工程.2007,28(1)：1-3
[10]宋欢,李波,李波平.PVC塑料包装中化学物总迁移的研究.化学研究与应用.2009,21(6)：934-936
[11]编委会欧盟食品接触材料安全法规实用指南.欧盟食品接触材料安全法规实用指南.北京,中国标准出版社,2005：69-73
[12]Commission Directive 2004/19/EC of 1 March 2004 amending Directive 2002/72/EC relating to plastic materials and articles intended to come into contact with foodstuffs.
[13]Commission Directive 2002/72/EC of 6 August 2002 relating to plastic materials and articles intended to come into contact with foodstuffs.
[14]BS EN13130-1-2004 Materials and articles in contact with foodstuffs-Plastics substances subject to limitation-Part 1:Guide to test methods for the specific migration of substances from plastics to foods and food simulants and the determination of substances in plastics and the selection of conditions of exposure to food simulants.
[15]Council Directive 82/711/EEC of 18 October 1982 laying down the basic rules necessary for testing migration of the constituents of plastic materials and articles intended to come into contact with foodstuffs.
[16]Piringer O. G., Baner A. L.食品用塑料包装材料阻隔功能、传质、品质保证和立法.北京,化学工业出版社,2004：175-176
[17]陈宇,王朝晖,郑德.实用塑料助剂手册.北京,化学工业出版社,2007：272-291
[1]李秀勇,牟俊,刘惠涛.超高效液相色谱-质谱法测定油脂中的10种抗氧化剂.分析化学.2008,36(3)：369-372
[2]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Determination of antioxidants by solid-phase extraction method in aqueous food simulants. Talanta.2005, 66:1103-1107
[3]Commission Directive 2002/72/EC of 6 August 2002 relating to plastic materials and articles intended to come into contact with foodstuffs. Official Journal of the European Communities.2002:218-220
[4]Commission Directive 2004/19/EC of 1 March 2004 amending Directive 2002/72/EC relating to plastic materials and articles intended to come into contact with foodstuffs. Official Journal of the European Communities.2004
[5]Martinez-Lopez S., Morales-Noe A., Pastor-Garcia A. Sample preparation improvement in polycyclic aromatic hydrocarbons determination in olive oils by gel permeation chromatography and liquid chromatography with fluorescence detection. Journal of AOAC International.2005,88(4):1247-1254
[6]Pardo Olga, Yusa Vicent, Leon Nuria. Development of a method for the analysis of seven banned azo-dyes in chilli and hot chilli food samples by pressurised liquid extraction and liquid chromatography with electrospray ionization-tandem mass spectrometry. Talanta.2009,78(1):178-186
[7]Cavaliere Brunella, Macchione Barbara, Sindona Giovanni. Tandem mass spectrometry in food safety assessment:The determination of phthalates in olive oil. Journal of Chromatography A.2008,1205(1-2):137-143
[8]Tovar Laura, Salafranca Jesus, Sanchez Cristina. Migration Studies To Assess the Safety in Use of a New Antioxidant Active Packaging. Journal of Agricultural and Food Chemistry.2005,53(13):5270-5275
[9]Farajzadeh M. A., Vardast M. R., Bahram M. Optimization of Dispersive Liquid-Liquid Microextraction of Irganox 1010 and Irgafos 168 from Polyolefins Before Liquid Chromatographic Analysis. Chromatographia.2009,69(5-6):409-419
[10]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Determination of antioxidant migration levels from low-density polyethylene films into food simulants. Journal of Chromatography A.2003,1018(1):53-62
[11]Francisco Maria Leonora dL, Resurreccion A. V. A. Development of a reversed-phase high performance liquid chromatography (RP-HPLC) procedure for the simultaneous determination of phenolic compounds in peanut skin extracts. Food Chemistry.2009,117(2):356-363
[12]Suarez Manuel, Macia Alba, Romero Maria-Paz. Improved liquid chromatography tandem mass spectrometry method for the determination of phenolic compounds in virgin olive oil. Journal of Chromatography A.2008,1214(1-2):90-99
[13]Marcato B., Guerra S., Vianello M. Migration of antioxidant additives from various polyolefinic plastics into oleaginous vehicles. International Journal of Pharmaceutics. 2003,257(1-2):217-225
[14]李鱼,刘建林,王晓丽.分散液-液微萃取／高效液相色谱法测定水样中的痕量双酚A.高等学校化学学报.2008,29(11)：2142-2148
[15]Spacil Zdenek, Novakova Lucie, Solich Petr. Analysis of phenolic compounds by high performance liquid chromatography and ultra performance liquid chromatography. Talanta.2008,76(1):189-199
[16]Noguerol-Cal Rosalia, Lopez-Vilarino Jose Manuel, Gonzalez-Rodriguez M. Victoria. Development of an ultraperformance liquid chromatography method for improved determination of additives in polymeric materials. Journal of Separation Science.2007, 30(15):2452-2459
[17]宋欢,李小梅,林勤保.超高效液相色谱测定市售塑料食品包装中的抗氧化剂.食品科学.2008,29(9)：448-450
[18]Jeon Dae Hoon, Park Gun Young, Kwak In Shin. Antioxidants and their migration into food simulants on irradiated LLDPE film. LWT-Food Science and Technology. 2007,40(1):151-156
[19]Minuti Lucio, Pellegrino Roberto. Determination of phenolic compounds in wines by novel matrix solid-phase dispersion extraction and gas chromatography/mass spectrometry. Journal of Chromatography A.2008,1185(1):23-30
[20]Lee Maw-Rong, Lin Chueh-Yu, Li Zu-Guang. Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry. Journal of Chromatography A.2006,1120(1-2): 244-251
[21]Poustka J., Dunovska L., Hajslova J.etal. Determination and occurrence of bisphenol a, bisphenol a diglycidyl ether, and bisphenol F diglycidyl ether, including their derivatives, in canned foodstuffs' from the Czech retail market. CZECH Journal of Food Sciences.2007.25(4):221-229
[22]Gonzalez M., Gallego M., Valcarcel M. Gas chromatographic flow method for the preconcentration and simultaneous determination of antioxidant and preservative additives in fatty foods. Journal of Chromatography A.1999,848(1-2):529-536
[23]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Antioxidant Content of and Migration from Commercial Polyethylene, Polypropylene, and Polyvinyl Chloride Packages. Journal of Agricultural and Food Chemistry.2007,55(8):3225-3231
[24]Juan F. Garcia-Reyes Carmen Ferrer M. Jose, Antonio Molina-Diaz Amadeo R. Fernandez-Alba. Determination of pesticide residues in olive oil and olives. TrAC Trends in Analytical Chemistry.2007,26(3):239-251
[25]Guardia-Rubio M., Marchal-Lopez R. M., Ayora-Canada M. J. Determination of pesticides in olives by gas chromatography using different detection systems. Journal of Chromatography A.2007,1145(1-2):195-203
[26]Sanchez Andres Garcia, Martos Natividad Ramos, Ballesteros Evaristo. Multiresidue analysis of pesticides in olive oil by gel permeation chromatography followed by gas chromatography-tandem mass-spectrometric determination. Analytica Chimica Acta.2006, 558(1-2):53-61
[27]Huang Zhiqiang, Li Yongjun, Chen Bo. Simultaneous determination of 102 pesticide residues in Chinese teas by gas chromatography-mass spectrometry. Journal of Chromatography B.2007,853(1-2):154-162
[1]黄崇杏,王志伟,王双飞.纸质食品包装材料中的残留污染物.包装工程.2007,28(7)：12-15
[2]Triantafyllou V. I., Akrida-Demertzi K., Demertzis P. G. A study on the migration of organic pollutants from recycled paperboard packaging materials to solid food matrices. Food Chemistry.2007,101(4):1759-1768
[3]Ozaki Asako, Yamaguchi Yukihiko, Fujita Tadao. Chemical analysis and genotoxicological safety assessment of paper and paperboard used for food packaging. Food and Chemical Toxicology.2004,42(8):1323-1337
[4]Nerin Cristina, Asensio Esther, Jimenez Carolina. Supercritical Fluid Extraction of Potential Migrants from Paper and Board Intended for Use As Food Packaging Materials. Analytical Chemistry.2002,74(22):5831-5836
[5]Jan Hrivfiak, Peter Tolgyessy, Sofia Figedyova. Solid-phase microcolumn extraction and gas chromatography-mass spectrometry identification of volatile organic compounds emitted by paper. Talanta. In Press, Corrected Proof.
[6]Nerin C., Asensio E. Behaviour of organic pollutants in paper and board samples intended to be in contact with food. Analytica Chimica Acta.2004,508(2):185-191
[7]Latorre A., Lacorte S., Barcel D. Determination of nonylphenol and octylphenol in paper by microwave-assisted extraction coupled to headspace solid-phase microextraction and gas chromatography-mass spectrometry. Journal of Chromatography A.2005,1065(2): 251-256
[8]Mario De Los Santos, Ramon Batlle, Jesus Salafranca. Subcritical water and dynamic sonication-assisted solvent extraction of fluorescent whitening agents and azo dyes in paper samples. Journal of Chromatography A.2005,1064(2):135-141
[9]Anderson W., Castle L. Benzophenone in cartonboard packaging materials and the factors that influence its migration into food. Food Additives and Contaminants.2003. 20(6):607-618
[10]Domeno C., Munizza G., Nerin C. Development of a solid-phase microextraction method for direct determination of pentachlorophenol in paper and board samples: Comparison with conventional extraction method. Journal of Chromatography A.2005, 1095(1-2):8-15
[11]Triantafyllou Vasileios I., Akrida-Demertzi Konstantoula, Demertzis Panagiotis G. Migration studies from recycled paper packaging materials:development of an analytical method for rapid testing. Analytica Chimica Acta.2002,467(1-2):253-260
[12]Styskin E. L., Gurvich Y. A. Gas chromatography of phenolic antioxidants. Journal of Chromatography A.1973,77(1):11-19
[13]Song Y.S., Park H.J., Komolprasert V. Analytical procedure for quantifying five compounds suspected as possible contaminants in recycled paper/paperboard for food packaging. Journal of Agricultural and Food Chemistry.2000.48(12):5856-5859
[14]Bradley E. L., Honkalampi-Hamalainen U., Weber A. The BIOSAFEPAPER project for in vitro toxicity assessments:Preparation, detailed chemical characterisation and testing of extracts from paper and board samples. Food and Chemical Toxicology.2008, 46(7):2498-2509
[15]Zdenek Spacil, Lucie Novakova, Petr Solich. Analysis of phenolic compounds by high performance liquid chromatography and ultra performance liquid chromatography. Talanta.2008,76(1):189-199
[16]Suarez Manuel, Macia Alba, Romero Maria-Paz. Improved liquid chromatography tandem mass spectrometry method for the determination of phenolic compounds in virgin olive oil. Journal of Chromatography A.2008,1214(1-2):90-99
[17]Lucie Novakova, Zdenek Spacil, Marcela Seifrtova. Rapid qualitative and quantitative ultra high performance liquid chromatography method for simultaneous analysis of twenty nine common phenolic compounds of various structures. Talanta. In Press, Accepted Manuscript
[18]Herrero M., Plaza M., Cifuentes A. Green processes for extraction of bioactives from Rosemary. Chemical and functional characterization via ultra performance liquid chromatography-tandem mass spectrometry and in-vitro assays. Journal of Chromatography A. In Press, Accepted Manuscript
[19]Samec D., Gruz J., Strnad M. Antioxidant and antimicrobial properties of Teucrium arduini L. (Lamiaceae) flower and leaf infusions (Teucrium arduini L. antioxidant capacity). Food and Chemical Toxicology. In Press, Corrected Proof
[20]ResAP(2002)1决议1号技术文件-拟与食品接触的纸和纸板材料及制品生产中使用的物质清单.
[21]Alvaro Garrido-Lopez, Tena Maria Teresa. Experimental design approach for the optimisation of pressurised fluid extraction of additives from polyethylene films. Journal of Chromatography A.2005,1099(1-2):75-83
[22]Harold J. Vandenburg, Anthony A. Clifford, Keith D. Bartle. A simple solvent selection method for accelerated solvent extraction of additives from polymers. Analyst. 1999,124:1707-1710
[23]Carabias-Martinez R., Rodriguez-Gonzalo E., Revilla-Ruiz P. Determination of endocrine-disrupting compounds in cereals by pressurized liquid extraction and liquid chromatography-mass spectrometry:Study of background contamination. Journal of Chromatography A.2006,1137(2):207-215
[2]郝晓秀.包装材料学.北京,印刷工业出版社,2000,2
[3]陈宇,王朝晖,郑德.实用塑料助剂手册.北京,化学工业出版社,2007,1
[4]黄崇杏,王志伟,王双飞.纸质食品包装材料中的残留污染物.12-15
[5]刘全校,刘伟.碱性纸张老化的影响因素探讨.黑龙江造纸.2002,30(4),24-25
[6]Triantafyllou V. I., Akrida-Demertzi K., Demertzis P. G. A study on the migration of organic pollutants from recycled paperboard packaging materials to solid food matrices. Food Chemistry.2007,101(4),1759-1768
[7]Council Directive 82/711/EEC of 18 October 1982 laying down the basic rules necessary for testing migration of the constituents of plastic materials and articles intended to come into contact with foodstuffs.
[8]Council Directive 85/572/EEC of 19 December 1985 laying down the list of simulants to be used for testing migration of constituents of plastic materials and articles intended to come into contact with foodstuffs. L372/14-21
[9]Commission Directive 97/48/EEC of 29 July 1997 amending for the second time Council Directive 82/711/EEC laying down the basic rules necessary for testing migration of the constituents of plastic materials and articles intended to come into contact with foodstuffs.
[10]Commission Directive 2002/72/EC of 6 August 2002 relating to plastic materials and articles intended to come into contact with foodstuffs.
[11]Commission Directive 2004/19/EC of 1 March 2004 amending Directive 2002/72/EC relating to plastic materials and articles intended to come into contact with foodstuffs.
[12]BS EN13130-1-2004 Materials and articles in contact with foodstuffs-Plastics substances subject to limitation-Part 1:Guide to test methods for the specific migration of substances from plastics to foods and food simulants and the determination of substances in plastics and the selection of conditions of exposure to food simulants.
[13]GB 2760-2007食品添加剂使用卫生标准.
[14]徐文达,程裕东,岑伟平.食品软包装材料与技术.北京,机械工业出版社,2003,35-49
[15]欧国勇,杨辉荣.纸塑复合胶粘剂的研究现状和动向.现代化工.2001,21(5)：17-21
[16]赵威威.塑料包装材料中化学物向脂肪类食品的迁移研究[硕士学位论文].江南大学.2007：5
[17]Monteiro, Nerin, Reyes. Migration of Tinuvin P, a UV Stabilizer, from PET Bottles into Fatty-Food Simulats. Packaging Technology and Science.1999,12:241-248
[18]欧盟食品接触材料安全法规实用指南编委会.欧盟食品接触材料安全法规实用指南.北京,中国标准出版社,2005：69-73
[19]黄崇杏,王志伟,王双飞.国内外食品接触纸质包装材料安全法规的现状.包装工程.2008,29(9)：204-207
[20]List of Indirect Additives Used in Food Contact Substances. http://www.accessdata.fda.gov/scripts/fcn/fcnNavigation.cfm?rpt=iaListing
[21]毛希琴,郑顺利,于利军.比较欧盟和美国的塑料食品包装材料管理体系与溶剂残留的限量规定.塑料.2008,37(4)：109-111
[22]CFSAN. Office Of Food Additive Safety. Preparation of Food Contact Notifications for Food Contact Substances:Toxicology Recommendations.
[23]CFSAN. Office of Food Additive Safety. Guidance for Industry-Preparation of Food Contact Notifications and Food Additive Petitions for Food Contact Substances: Chemistry Recommendations, Final Guidance.
[24]Choy Thomas K., Quattrone Jr Joseph J., Alicino Nicholas J. A gas chromatographic method for the determination of the antioxidants bha, bht and ethoxyquin in aqueous and in hydrocarbon soluble samples. Journal of Chromatography A.1963,12:171-177
[25]Lee Maw-Rong, Lin Chueh-Yu, Li Zu-Guang. Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry. Journal of Chromatography A.2006,1120(1-2): 244-251
[26]Gonzalez M., Gallego M., Valcarcel M. Gas chromatographic flow method for the preconcentration and simultaneous determination of antioxidant and preservative additives in fatty foods. Journal of Chromatography A.1999,848(1-2):529-536
[27]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Antioxidant Content of and Migration from Commercial Polyethylene, Polypropylene, and Polyvinyl Chloride Packages. Journal of Agricultural and Food Chemistry.2007,55(8):3225-3231
[28]Minuti Lucio, Pellegrino Roberto. Determination of phenolic compounds in wines by novel matrix solid-phase dispersion extraction and gas chromatography/mass spectrometry. Journal of Chromatography A.2008,1185(1):23-30
[29]Pardo Olga, Yusa Vicent, Leon Nuria. Development of a method for the analysis of seven banned azo-dyes in chilli and hot chilli food samples by pressurised liquid extraction and liquid chromatography with electrospray ionization-tandem mass spectrometry. Talanta.2009,78(1):178-186
[30]刘宏程,黎其万,佴注.基质固相分散-HPLC法快速测定植物油中抗氧化剂.食品科学.2007,28(1)：253-255
[31]李秀勇,牟峻,刘惠涛.超高效液相色谱-质谱法测定油脂中的10种抗氧化剂.分析化学.2008,36(3)：369-372
[32]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Determination of antioxidants by solid-phase extraction method in aqueous food simulants. Talanta.2005,66:1103-1107
[33]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Determination of antioxidant migration levels from low-density polyethylene films into food simulants. Journal of Chromatography A.2003,1018(1):53-62
[34]Pentimalli M., Ragni P., Righini G. Polymers and paper as packaging materials of irradiated foodAn NMR study. Radiation Physics and Chemistry.2000,57(3-6):385-388
[35]Sanches-Silva A., Sendon-Garcia R., Cooper I. Compilation of analytical methods and guidelines for the determination of selected model migrants from plastic packaging. Trends in Food Science & Technology.2006,17(10):535-546
[36]李波平,林勤保,宋欢.快速溶剂萃取-高效液相色谱测定塑料中邻苯二甲酸酯类化合物.应用化学.2008,(1)：63-66
[37]Vandenburg Harold J., Clifford Anthony A., Bartle Keith D. A simple solvent selection method for accelerated solvent extraction of additives from polymers. The Analyst.1999,124(11):1707-1710
[38]Camacho Walker, Karlsson Sigbritt. Quality-determination of recycled plastic packaging waste by identification of contaminants by GC-MS after microwave assisted extraction (MAE). Polymer Degradation and Stability.2000,71(1):123-134
[39]Alvaro Garrido-Lopez, Tena Maria Teresa. Experimental design approach for the optimisation of pressurised fluid extraction of additives from polyethylene films. Journal of Chromatography A.2005,1099(1-2):75-83
[40]Silva A. Sanches, Cooper I., Franz R. Revision of analytical strategies to evaluate different migrants from food packaging materials. Trends in Food Science and Technology.2006,17(7):354-366
[41]Freire M. T., Castle L., Reyes F. G. R. Thermal Stability of Polyethylene Terephthalate Food Contact Material:Formation of Volatiles from Retail Samples and Implications for Recycling. Food Additives and Contaminants.1998,15:473-480
[42]Song Y.S., Park H.J., Komolprasert V. Analytical procedure for quantifying five compounds suspected as possible contaminants in recycled paper/paperboard for food packaging. Journal of Agricultural and Food Chemistry.2000.48(12):5856-5859
[43]Nerin Cristina, Asensio Esther, Jimenez Carolina. Supercritical Fluid Extraction of Potential Migrants from Paper and Board Intended for Use As Food Packaging Materials. Analytical Chemistry.2002,74(22):5831-5836
[44]Mario De Los Santos, Ramon Batlle, Jesus Salafranca. Subcritical water and dynamic sonication-assisted solvent extraction of fluorescent whitening agents and azo dyes in paper samples. Journal of Chromatography A.2005,1064(2):135-141
[45]Domeno C., Munizza G., Nerin C. Development of a solid-phase microextraction method for direct determination of pentachlorophenol in paper and board samples: Comparison with conventional extraction method. Journal of Chromatography A.2005, 1095(1-2):8-15
[46]Latorre A., Lacorte S., Barcel D. Determination of nonylphenol and octylphenol in paper by microwave-assisted extraction coupled to headspace solid-phase microextraction and gas chromatography-mass spectrometry. Journal of Chromatography A.2005,1065(2): 251-256
[47]Ozaki Asako, Yamaguchi Yukihiko, Fujita Tadao. Chemical analysis and genotoxicological safety assessment of paper and paperboard used for food packaging. Food and Chemical Toxicology.2004,42(8):1323-1337
[48]Anderson W., Castle L. Benzophenone in cartonboard packaging materials and the factors that influence its migration into food. Food Additives and Contaminants.2003. 20(6):607-618
[49]Chung D., Papadakis S. E., Yam K. L. Simple models for assessing migration from food-packaging films. Food Additives & Contaminants.2002,19(6):611-617
[50]Triantafyllou Vasileios I., Akrida-Demertzi Konstantoula, Demertzis Panagiotis G. Migration studies from recycled paper packaging materials:development of an analytical method for rapid testing. Analytica Chimica Acta.2002,467(1-2):253-260
[51]Marcato B., Guerra S., Vianello M. Migration of antioxidant additives from various polyolefinic plastics into oleaginous vehicles. International Journal of Pharmaceutics. 2003,257(1-2):217-225
[52]Waldeback Monica, Jansson Charlotte, J Francisco. Accelerated solvent extraction of the antioxidant Irganox1076 in linear low density polyethylene (LLDPE) granules before and after g-irradiation. The Analyst.1998,123:1205-1207
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[55]刘志刚,胡长鹰,王志伟.3种聚烯烃抗氧剂迁移的试验分析及数值模拟.包装工程.2007,28(1)：1-3
[56]王正林,刘志刚,胡长鹰.聚烯烃抗氧剂1076和168在食用油中的迁移研究.包装工程.2007,28(6)：1-3
[57]宋欢,李波,李波平.PVC塑料包装中化学物总迁移的研究.化学研究与应用.2009,21(6)：934-936
[58]Piringer O. G., Baner A. L.食品用塑料包装材料阻隔功能、传质、品质保证和立法.北京,化学工业出版社,175-176
[1]陈宇,王朝晖,郑德.实用塑料助剂手册.北京,化学工业出版社,2007：1
[2]Suman Michele, La Tegola Stefano, Catellani Dante. Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry Method for the Determination of Epoxidized Soybean Oil in Food Products. Journal of Agricultural and Food Chemistry.2005,53(26):9879-9884
[3]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Determination of antioxidant migration levels from low-density polyethylene films into food simulants. Journal of Chromatography A.2003,1018(1):53-62
[4]Jeon Dae Hoon, Park Gun Young, Kwak In Shin. Antioxidants and their migration into food simulants on irradiated LLDPE film. LWT-Food Science and Technology.2007, 40(1):151-156
[5]Alvaro Garrido-Lopez, Tena Maria Teresa. Experimental design approach for the optimisation of pressurised fluid extraction of additives from polyethylene films. Journal of Chromatography A.2005,1099(1-2):75-83
[6]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Antioxidant Content of and Migration from Commercial Polyethylene, Polypropylene, and Polyvinyl Chloride Packages. Journal of Agricultural and Food Chemistry.2007,55(8):3225-3231
[7]宋欢,李波,李波平.PVC塑料包装中化学物总迁移的研究.化学研究与应用.2009,21(6)：934-936
[8]韩兆让,卢爱玲.聚合物包装材料上单体分子的迁移.塑料包装.1996,6(1)：9-13
[9]Molander P., Haugland K., Hegna D. R. Determination of low levels of an antioxidant in polyolefins by large-volume injection temperature programmed packed capillary liquid chromatography. Journal of Chromatography A.1999,864(1):103-109
[10]Vandenburg Harold J., Clifford Anthony A., Bartle Keith D. Analytical Extraction of Additives From Polymers. The Analyst.1997,122:101R-115R
[11]李秀勇,牟峻,刘惠涛.超高效液相色谱-质谱法测定油脂中的10种抗氧化剂.分析化学.2008,36(3)：369-372
[12]刘宏程,黎其万,佴注.基质固相分散-HPLC法快速测定植物油中抗氧化剂.食品科学.2007,28(1)：253-255
[13]Noguerol-Cal Rosalia, Lopez-Vilarino Jose Manuel, Gonzalez-Rodriguez M. Victoria. Development of an ultraperformance liquid chromatography method for improved determination of additives in polymeric materials. Journal of Separation Science.2007, 30(15):2452-2459
[14]Camacho Walker, Karlsson Sigbritt. Quality-determination of recycled plastic packaging waste by identification of contaminants by GC-MS after microwave assisted extraction (MAE). Polymer Degradation and Stability.2000,71(1):123-134
[15]Minuti Lucio, Pellegrino Roberto. Determination of phenolic compounds in wines by novel matrix solid-phase dispersion extraction and gas chromatography/mass spectrometry. Journal of Chromatography A.2008,1185(1):23-30
[16]Commission Directive 2004/19/EC of 1 March 2004 amending Directive 2002/72/EC relating to plastic materials and articles intended to come into contact with foodstuffs.
[17]Commission Directive 2002/72/EC of 6 August 2002 relating to plastic materials and articles intended to come into contact with foodstuffs.218-220
[18]Council Directive 85/572/EEC of 19 December 1985 laying down the list of simulants to be used for testing migration of constituents of plastic materials and articles intended to come into contact with foodstuffs. L372/14-21
[1]Commission Directive 97/48/EC of 29 July 1997 amending for the second time Council Directive 82/711/EEC laying down the basic rules necessary for testing migration of the constituents of plastic materials and articles intended to come into contact with foodstuffs.
[2]Council Directive 85/572/EEC of 19 December 1985 laying down the list of simulants to be used for testing migration of constituents of plastic materials and articles intended to come into contact with foodstuffs.
[3]Helmroth Erika, Rijk Rinus, Dekker Matthijs. Predictive modelling of migration from packaging materials into food products for regulatory purposes. Trends in Food Science & Technology.2002,13(3):102-109
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[1]李秀勇,牟俊,刘惠涛.超高效液相色谱-质谱法测定油脂中的10种抗氧化剂.分析化学.2008,36(3)：369-372
[2]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Determination of antioxidants by solid-phase extraction method in aqueous food simulants. Talanta.2005, 66:1103-1107
[3]Commission Directive 2002/72/EC of 6 August 2002 relating to plastic materials and articles intended to come into contact with foodstuffs. Official Journal of the European Communities.2002:218-220
[4]Commission Directive 2004/19/EC of 1 March 2004 amending Directive 2002/72/EC relating to plastic materials and articles intended to come into contact with foodstuffs. Official Journal of the European Communities.2004
[5]Martinez-Lopez S., Morales-Noe A., Pastor-Garcia A. Sample preparation improvement in polycyclic aromatic hydrocarbons determination in olive oils by gel permeation chromatography and liquid chromatography with fluorescence detection. Journal of AOAC International.2005,88(4):1247-1254
[6]Pardo Olga, Yusa Vicent, Leon Nuria. Development of a method for the analysis of seven banned azo-dyes in chilli and hot chilli food samples by pressurised liquid extraction and liquid chromatography with electrospray ionization-tandem mass spectrometry. Talanta.2009,78(1):178-186
[7]Cavaliere Brunella, Macchione Barbara, Sindona Giovanni. Tandem mass spectrometry in food safety assessment:The determination of phthalates in olive oil. Journal of Chromatography A.2008,1205(1-2):137-143
[8]Tovar Laura, Salafranca Jesus, Sanchez Cristina. Migration Studies To Assess the Safety in Use of a New Antioxidant Active Packaging. Journal of Agricultural and Food Chemistry.2005,53(13):5270-5275
[9]Farajzadeh M. A., Vardast M. R., Bahram M. Optimization of Dispersive Liquid-Liquid Microextraction of Irganox 1010 and Irgafos 168 from Polyolefins Before Liquid Chromatographic Analysis. Chromatographia.2009,69(5-6):409-419
[10]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Determination of antioxidant migration levels from low-density polyethylene films into food simulants. Journal of Chromatography A.2003,1018(1):53-62
[11]Francisco Maria Leonora dL, Resurreccion A. V. A. Development of a reversed-phase high performance liquid chromatography (RP-HPLC) procedure for the simultaneous determination of phenolic compounds in peanut skin extracts. Food Chemistry.2009,117(2):356-363
[12]Suarez Manuel, Macia Alba, Romero Maria-Paz. Improved liquid chromatography tandem mass spectrometry method for the determination of phenolic compounds in virgin olive oil. Journal of Chromatography A.2008,1214(1-2):90-99
[13]Marcato B., Guerra S., Vianello M. Migration of antioxidant additives from various polyolefinic plastics into oleaginous vehicles. International Journal of Pharmaceutics. 2003,257(1-2):217-225
[14]李鱼,刘建林,王晓丽.分散液-液微萃取／高效液相色谱法测定水样中的痕量双酚A.高等学校化学学报.2008,29(11)：2142-2148
[15]Spacil Zdenek, Novakova Lucie, Solich Petr. Analysis of phenolic compounds by high performance liquid chromatography and ultra performance liquid chromatography. Talanta.2008,76(1):189-199
[16]Noguerol-Cal Rosalia, Lopez-Vilarino Jose Manuel, Gonzalez-Rodriguez M. Victoria. Development of an ultraperformance liquid chromatography method for improved determination of additives in polymeric materials. Journal of Separation Science.2007, 30(15):2452-2459
[17]宋欢,李小梅,林勤保.超高效液相色谱测定市售塑料食品包装中的抗氧化剂.食品科学.2008,29(9)：448-450
[18]Jeon Dae Hoon, Park Gun Young, Kwak In Shin. Antioxidants and their migration into food simulants on irradiated LLDPE film. LWT-Food Science and Technology. 2007,40(1):151-156
[19]Minuti Lucio, Pellegrino Roberto. Determination of phenolic compounds in wines by novel matrix solid-phase dispersion extraction and gas chromatography/mass spectrometry. Journal of Chromatography A.2008,1185(1):23-30
[20]Lee Maw-Rong, Lin Chueh-Yu, Li Zu-Guang. Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry. Journal of Chromatography A.2006,1120(1-2): 244-251
[21]Poustka J., Dunovska L., Hajslova J.etal. Determination and occurrence of bisphenol a, bisphenol a diglycidyl ether, and bisphenol F diglycidyl ether, including their derivatives, in canned foodstuffs' from the Czech retail market. CZECH Journal of Food Sciences.2007.25(4):221-229
[22]Gonzalez M., Gallego M., Valcarcel M. Gas chromatographic flow method for the preconcentration and simultaneous determination of antioxidant and preservative additives in fatty foods. Journal of Chromatography A.1999,848(1-2):529-536
[23]Dopico-Garcia M. S., Lopez-Vilarino J. M., Gonzalez-Rodriguez M. V. Antioxidant Content of and Migration from Commercial Polyethylene, Polypropylene, and Polyvinyl Chloride Packages. Journal of Agricultural and Food Chemistry.2007,55(8):3225-3231
[24]Juan F. Garcia-Reyes Carmen Ferrer M. Jose, Antonio Molina-Diaz Amadeo R. Fernandez-Alba. Determination of pesticide residues in olive oil and olives. TrAC Trends in Analytical Chemistry.2007,26(3):239-251
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[26]Sanchez Andres Garcia, Martos Natividad Ramos, Ballesteros Evaristo. Multiresidue analysis of pesticides in olive oil by gel permeation chromatography followed by gas chromatography-tandem mass-spectrometric determination. Analytica Chimica Acta.2006, 558(1-2):53-61
[27]Huang Zhiqiang, Li Yongjun, Chen Bo. Simultaneous determination of 102 pesticide residues in Chinese teas by gas chromatography-mass spectrometry. Journal of Chromatography B.2007,853(1-2):154-162
[1]黄崇杏,王志伟,王双飞.纸质食品包装材料中的残留污染物.包装工程.2007,28(7)：12-15
[2]Triantafyllou V. I., Akrida-Demertzi K., Demertzis P. G. A study on the migration of organic pollutants from recycled paperboard packaging materials to solid food matrices. Food Chemistry.2007,101(4):1759-1768
[3]Ozaki Asako, Yamaguchi Yukihiko, Fujita Tadao. Chemical analysis and genotoxicological safety assessment of paper and paperboard used for food packaging. Food and Chemical Toxicology.2004,42(8):1323-1337
[4]Nerin Cristina, Asensio Esther, Jimenez Carolina. Supercritical Fluid Extraction of Potential Migrants from Paper and Board Intended for Use As Food Packaging Materials. Analytical Chemistry.2002,74(22):5831-5836
[5]Jan Hrivfiak, Peter Tolgyessy, Sofia Figedyova. Solid-phase microcolumn extraction and gas chromatography-mass spectrometry identification of volatile organic compounds emitted by paper. Talanta. In Press, Corrected Proof.
[6]Nerin C., Asensio E. Behaviour of organic pollutants in paper and board samples intended to be in contact with food. Analytica Chimica Acta.2004,508(2):185-191
[7]Latorre A., Lacorte S., Barcel D. Determination of nonylphenol and octylphenol in paper by microwave-assisted extraction coupled to headspace solid-phase microextraction and gas chromatography-mass spectrometry. Journal of Chromatography A.2005,1065(2): 251-256
[8]Mario De Los Santos, Ramon Batlle, Jesus Salafranca. Subcritical water and dynamic sonication-assisted solvent extraction of fluorescent whitening agents and azo dyes in paper samples. Journal of Chromatography A.2005,1064(2):135-141
[9]Anderson W., Castle L. Benzophenone in cartonboard packaging materials and the factors that influence its migration into food. Food Additives and Contaminants.2003. 20(6):607-618
[10]Domeno C., Munizza G., Nerin C. Development of a solid-phase microextraction method for direct determination of pentachlorophenol in paper and board samples: Comparison with conventional extraction method. Journal of Chromatography A.2005, 1095(1-2):8-15
[11]Triantafyllou Vasileios I., Akrida-Demertzi Konstantoula, Demertzis Panagiotis G. Migration studies from recycled paper packaging materials:development of an analytical method for rapid testing. Analytica Chimica Acta.2002,467(1-2):253-260
[12]Styskin E. L., Gurvich Y. A. Gas chromatography of phenolic antioxidants. Journal of Chromatography A.1973,77(1):11-19
[13]Song Y.S., Park H.J., Komolprasert V. Analytical procedure for quantifying five compounds suspected as possible contaminants in recycled paper/paperboard for food packaging. Journal of Agricultural and Food Chemistry.2000.48(12):5856-5859
[14]Bradley E. L., Honkalampi-Hamalainen U., Weber A. The BIOSAFEPAPER project for in vitro toxicity assessments:Preparation, detailed chemical characterisation and testing of extracts from paper and board samples. Food and Chemical Toxicology.2008, 46(7):2498-2509
[15]Zdenek Spacil, Lucie Novakova, Petr Solich. Analysis of phenolic compounds by high performance liquid chromatography and ultra performance liquid chromatography. Talanta.2008,76(1):189-199
[16]Suarez Manuel, Macia Alba, Romero Maria-Paz. Improved liquid chromatography tandem mass spectrometry method for the determination of phenolic compounds in virgin olive oil. Journal of Chromatography A.2008,1214(1-2):90-99
[17]Lucie Novakova, Zdenek Spacil, Marcela Seifrtova. Rapid qualitative and quantitative ultra high performance liquid chromatography method for simultaneous analysis of twenty nine common phenolic compounds of various structures. Talanta. In Press, Accepted Manuscript
[18]Herrero M., Plaza M., Cifuentes A. Green processes for extraction of bioactives from Rosemary. Chemical and functional characterization via ultra performance liquid chromatography-tandem mass spectrometry and in-vitro assays. Journal of Chromatography A. In Press, Accepted Manuscript
[19]Samec D., Gruz J., Strnad M. Antioxidant and antimicrobial properties of Teucrium arduini L. (Lamiaceae) flower and leaf infusions (Teucrium arduini L. antioxidant capacity). Food and Chemical Toxicology. In Press, Corrected Proof
[20]ResAP(2002)1决议1号技术文件-拟与食品接触的纸和纸板材料及制品生产中使用的物质清单.
[21]Alvaro Garrido-Lopez, Tena Maria Teresa. Experimental design approach for the optimisation of pressurised fluid extraction of additives from polyethylene films. Journal of Chromatography A.2005,1099(1-2):75-83
[22]Harold J. Vandenburg, Anthony A. Clifford, Keith D. Bartle. A simple solvent selection method for accelerated solvent extraction of additives from polymers. Analyst. 1999,124:1707-1710
[23]Carabias-Martinez R., Rodriguez-Gonzalo E., Revilla-Ruiz P. Determination of endocrine-disrupting compounds in cereals by pressurized liquid extraction and liquid chromatography-mass spectrometry:Study of background contamination. Journal of Chromatography A.2006,1137(2):207-215