磨牙症监测治疗仪的研制
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摘要
磨牙症是一种由于非生理功能运动发生的牙齿磨动或咬紧的现象。该病症危害性巨大,目前由于没有明确的病因,还没有统一的治疗方法。在众多的治疗方法中,牙合板的治疗是较为有效的一种。
本课题在牙合板治疗的基础上,开发了一种有良好的监护功能、治疗手段,同时也能满足医学研究需要的磨牙症监护设备。论文首先介绍了国内外的研究现状,并对现有的几种典型磨牙监护设备进行了分析,然后给出了本课题所开发系统的结构和设计理念。
所开发仪器按照功能将其分为四个模块。微弱信号模块设计并实现了采集磨牙力度信号,并设计了信号处理电路,为了进一步改善磨牙信号,系统采用了PVDF压电薄膜自行制作了符合要求的压电传感器。信号控制模块通过单片机实现了对系统流程的控制。包括实现了对采集来的磨牙信号进行模数转换、语言芯片的录音控制和对蓝牙模块的流程控制。并提供了与PC机之间的串口传输方式。手机通信模块是通过控制蓝牙模块实现与手机的无线连接,并在手机上开发软件处理磨牙信号,并以短信的方式发送到医生的手机上。生物反馈治疗模块包括两种生物反馈治疗方式:音乐反馈和振动反馈。通过控制语音芯片和振动模块实现了对患者的音乐治疗和振动治疗。
论文的最后还提出了仪器的进一步完善方案。本课题的开发将为磨牙症的治疗和深入研究奠定基础。
Bruxism is a non-physiological function of the movement of teeth grinding or clenching type. It is great harmful, but the disease has neither a clear cause nor a uniform effective treatment now. Among these treatments, biteplate treatment is a more effective method.
So we have developed a good function of guardianship and effective treatment device which based on biteplate treatment, as well as to meet the needs of medical research equipments of Bruxism. This article introduced the status of bruxism research at home and abroad at first, and compared the different of several classic bruxism monitor devices which made by some universities and hospitals in the world. And then the structure of device and the improved methods were elaborated.
The device was comprised by four parts. The weak signal acquistion module was designed to obtain the datas of the teeth force in bruxism which including signal processing circuit. In order to further improve the signal of the teeth force, PVDF (Polyvinylidene Fluoride) piezoelectric films was used to make a piezoelectric sensor to meet the requirements of system. The function of the signal control module was achieved by single-chip, which is in charge of AD changing of the acquired signal, controlling the recording function of the audio chip, the work of the Bluetooth module and so on. The third module was designed to communicate with mobile phone by wireless ways and then deal with the signal of teeth force by the software which developed by ourself. Biofeedback module includes two kinds of biofeedback ways: sound feedback and vibrating feedback treatment. These two methods were realized by using audio chip and vibrating module.
The further improvements of the device will be investigated in the future. Our work will lay a base for curing the bruxism.
本课题在牙合板治疗的基础上,开发了一种有良好的监护功能、治疗手段,同时也能满足医学研究需要的磨牙症监护设备。论文首先介绍了国内外的研究现状,并对现有的几种典型磨牙监护设备进行了分析,然后给出了本课题所开发系统的结构和设计理念。
所开发仪器按照功能将其分为四个模块。微弱信号模块设计并实现了采集磨牙力度信号,并设计了信号处理电路,为了进一步改善磨牙信号,系统采用了PVDF压电薄膜自行制作了符合要求的压电传感器。信号控制模块通过单片机实现了对系统流程的控制。包括实现了对采集来的磨牙信号进行模数转换、语言芯片的录音控制和对蓝牙模块的流程控制。并提供了与PC机之间的串口传输方式。手机通信模块是通过控制蓝牙模块实现与手机的无线连接,并在手机上开发软件处理磨牙信号,并以短信的方式发送到医生的手机上。生物反馈治疗模块包括两种生物反馈治疗方式:音乐反馈和振动反馈。通过控制语音芯片和振动模块实现了对患者的音乐治疗和振动治疗。
论文的最后还提出了仪器的进一步完善方案。本课题的开发将为磨牙症的治疗和深入研究奠定基础。
Bruxism is a non-physiological function of the movement of teeth grinding or clenching type. It is great harmful, but the disease has neither a clear cause nor a uniform effective treatment now. Among these treatments, biteplate treatment is a more effective method.
So we have developed a good function of guardianship and effective treatment device which based on biteplate treatment, as well as to meet the needs of medical research equipments of Bruxism. This article introduced the status of bruxism research at home and abroad at first, and compared the different of several classic bruxism monitor devices which made by some universities and hospitals in the world. And then the structure of device and the improved methods were elaborated.
The device was comprised by four parts. The weak signal acquistion module was designed to obtain the datas of the teeth force in bruxism which including signal processing circuit. In order to further improve the signal of the teeth force, PVDF (Polyvinylidene Fluoride) piezoelectric films was used to make a piezoelectric sensor to meet the requirements of system. The function of the signal control module was achieved by single-chip, which is in charge of AD changing of the acquired signal, controlling the recording function of the audio chip, the work of the Bluetooth module and so on. The third module was designed to communicate with mobile phone by wireless ways and then deal with the signal of teeth force by the software which developed by ourself. Biofeedback module includes two kinds of biofeedback ways: sound feedback and vibrating feedback treatment. These two methods were realized by using audio chip and vibrating module.
The further improvements of the device will be investigated in the future. Our work will lay a base for curing the bruxism.
引文
[1]张静露,殷新民,磨牙症研究进展,国外医学口腔医学分册,2003, 30(1):49～50.
[2]李雪铃,林雪峰,磨牙症与颞下颌关节紊乱病关系的研究,国际口腔医学杂志,2007, 34(1):59～60.
[3] Kreiner M,Betancor E,Clark GT,Occlusal stabilization appliances,Evidence of their efficacy,J Am Dent Assoc,2001,132(6):770～777.
[4] Pierce C J,Chrisman K,Bennett M E,et al,Stress,anticipatory stress,and psychologic measure related to sleep bruxism,J Orofac Pain,1995,9(1):51～56.
[5] Jorgic Srdjak K,Ivezic S,Cekic Arambasim A,et al,Bruxism and paychobiological model of personal,Coll Antropol,1998,22:205～212.
[6] Vanderas A P,Manetas K J,Relationship between malocclusion and bruxism in children and adolescents:a review,Pediatr Dent,1995,17(1):7～12.
[7] Macaluso. G M,Guerra P,Di Giovanni G et al,Sleep bruxism is a disorder related to periodic arousals during sleep,J Dent Rea,1998,77(4):565～573.
[8] Wise M E,Citalopram-induced bruxism,Br J Psychiatry,2001,178(2):182.
[9] Lobbezoo F,Soucy J P,Montplaisir J Y,et al,Striatal D2 receptor binding in sleep bruxism :a controlled study with iodine-123-iodobenzamide and single-photon-emission computed tomography,J Dent Res,1996,75(10):1804～1810.
[10]殷新民,张道珍,临床口腔医学杂志,2000,16(2):115～116.
[11] Tan E K,Jankovie J,Treating severe bruxism with botulinum toxin,J Am Dent Assoc,2000,131(2):211～216.
[12] Brown E S,Hong S C,Antidepressant-induced bruxism successfully treated with gabapentin,Journal of the American Dental Association,1999,130:1467～1469.
[13] Pryor JL,Kent-First M,Muallem A,et al,Microdeletion in the Ychromosome of infertile men,N Engl J Med,1997,336(8):534-539.
[14] Jattee M S,Bostwick J M,Buapirone as antidote to veolafaxine-included bruxism,Paychosomatics,2000,41(6):535～536.
[15] Rugh JD,Johnson RW,Temporal analysis of nocturnal bruxism during EMG feedback,J Periodontol,1981,52:263～265.
[16]符鹤,周忠华,蓝牙技术的原理及其应用,电脑应用技术,2006,67:40～51.
[17] NicolasRouhana,Horlait.,Bluetooth Web Internet Gateway,Proceedings of Seventh International Symposium on Computers and Communications,2002,7:679～684.
[18] David Johnson,Hardware and Software Implications of Creating Bluetooth Scatternet Devices,Africon Conference in Africa,2004,1:211～215.
[19] Glenford J.Myers,The art of software testing,New York,John Wiley sons,1979.
[20]李朝青,单片机原理及接口技术,北京:北京航空航天大学出版社,1994:58~60.
[21] Y. Amemori*,S. Yamashita*,M. Ai*,et al. Influence of nocturnal bruxism on the stomatognathic system PartⅠ:a new device for measuring mandibular movement during sleep,Journal of Oral Rehabilitation 2001,28:943～949.
[22] Lavigne,GJ,Romple PH,Montplaisir JY,Sleep brixsm:validity of clinical research diagnostic criteria in a controlled polysomngraphic study,Journal of Dental Research,75:546.
[23] Ikeda. T,Nishigawa. K,Criteria for the detection of sleep-associated bruxism in humans,Journal of Orofacial Pain,1996,10:270.
[24] Minagi. S,Akamatsu. T,Matsunaga. T,et al,Relationship between mandibular position and the coordination of masseter muscle activity during sleep in human,Journal of Oral Rehabilitation,1998,25:902.
[25] Ryuji Sakagami,Takeshi Horii,Shuichi Ino,et al,Development of a portable bruxism monitoring and analysis device equipped with a microcomputer and its practical application,Frontiers Med. Biol. Engng,2002,11(4):295～306.
[26] T. Kampe,G. Edman,G. Bader,et al,Personality traits in a group of subjects with long-standing bruxism behaviour,J. Oral Rehabil. 1997,24:588～593.
[27] R. Sakagami,H. Kato,Y. Tsuchida,I. Yoshida,et al,Development of automatic bruxism analysis system,Jpn. J. Conserv. Dent,2002,45:349~355.
[28] R. Ichiki,Y. Tsukiyama and K. Koyano,Development of a portable electromyographic recording device and an application for the evaluation of the day to day variation of nocturnal masseter muscle activity,J. Jpn. Soc. Stomatognath. Funct,1999,6:67～77.
[29] G. J. Lavine,P. H. Rpmpre,J. Y. Montplaisir,Sleep bruxism:validity of clinical research diagnostic criteria in a controlled polysomnographic study,J. Dent. Res,1996,77:546～552.
[30] C. P. Fernandes,L. B. Psarras,L. B. Freitas,et al,Jaw-closing muscles:electromyographic activity of human subjects with reduced periodontal support,J. Oral Rehab,1994,21:165～175.
[31] H. Hanamura,F. Houston and H. Rylander,Periodontal status and bruxism:a comparative study of patients with periodontal disease and occlusal parafunctions,J. Periodontol. 1987,58,173～176.
[32] Treacy K,Awareness/relaxation training and transcutaneous electrical neural stimulation in the treatment of bruxism,J Oral Rehabil,1999,26:280～287.
[33]张鸿懿,音乐疗法(一),中国自然医学杂志,1999,11:1～2.
[34]普凯元,音乐治疗的理论基础,医学与哲学,1991,(1):39.
[35] Holmegn K,Sheikholeslam A,Riise C,Effect of a full-arch maxillary occlusal splint on parafunctional activity during sleep in patients with nocturnal bruxism and sign and sympotoms of craniomandibular disorder,J Prosthet Dent,1993,69:293～297.
[36]刘迎春,叶湘滨,传感器原理设计与应用,北京:国防科技大学出版社,1997:107～121.
[37]于世风,口腔组织病理学,北京:人民卫生出版社,2000:9～11.
[38] Y. He,H Liang,The role of government in china’s healthcare IT Development,Harvard China Rev,2006,7(1):58.
[39] Pal A,Mbarika,Telemedicine diffusion in a developing Country:The case of India,IEEE Transactions on Information Technology in Biomedicine,2005,2005,9(1):59.
[40]曾庆勇,微弱信号检测,杭州:浙江大学出版社,1994:323～325.
[41] Zarcone VP, Sleep hygiene. In:Kryger MH,Roth T,Dement WC.Principles and practice of sleep medicine, 2nd ed. Philadelphia:WBSaunders,1994,542-546.
[42] Clark GT,Koyano K,Browne PA,Oral motor disorders in humans,J Calif Dent Assoc,1993,21:19～30.
[43] Watson TS,Effectiveness of arousal and arousal plus overcorrection to reduce nocturnal bruxism,J Behav Ther Exp Psychiatry,1993,24:181～185.
[44] Holmgren K,Sheikholeslam A,Riise C,Effect of a full-arch maxillary occlusal splint on parafunctional activity during sleep in patients with nocturnal bruxism and signs and symptoms of craniomandibular disorders,J Prosthet Dent,1993,69:293～297.
[45]孙建民,杨清梅,传感器技术,北京:清华大学出版社,2006:231～239.
[46]压电薄膜传感器技术(国际互联网版本),精量电子(深圳)有限公司,1998.
[47]金观昌,于淼,压电薄膜压力分布计算机测试系统研究,清华大学学报(自然科学版),1998,38(2):21～24.
[48]万建国,朱纪军,石立华,PVDF压电薄膜在结构监测中的应用初探,传感器学报,1998,1:18～24.
[49]罗志增,何发昌,用PVDF制作的触觉传感器,传感器技术,1997,16(3):1～4.
[50]邹建华,彭宽平,姜新桥,电工电子技术基础,武汉:华中科技大学出版社,2005:442.
[51] Choi YB,Krause,JS.Telemedicine in the USA: standardization through information management and technical applications,IEEE Communications Magazine,2006,44(4):41.
[52]张卉,王运栋,曲爱华,基于蓝牙的设备管理信息系统研究,微计算机信息,2005,36:119～121.
[53] Bluetooth SIG Specification of the Bluetooth System Core,Version 1.1,England Cambridge Siliconkadio Co. ,Ltd,2001.
[54] Bruce Eckel,Java编程思想(候捷),北京:机械工业出版社,1994:39.
[55] Andre N. Klingsheim,J2ME Bluetooth Programming,Department of Informatics University of Bergen,2004.
[56] Sense8 Corporation,World Tool Kit C++ Programming Guide,USA,Sense8 Corporation,1999:10.
[57] Watanabe T,Baba K,Yamagata K,et al,A vibratory stimulationbased inhibition system for nocturnal bruxism:a clinical report,J Prosthet Dent,2001,85:233～235.
[2]李雪铃,林雪峰,磨牙症与颞下颌关节紊乱病关系的研究,国际口腔医学杂志,2007, 34(1):59～60.
[3] Kreiner M,Betancor E,Clark GT,Occlusal stabilization appliances,Evidence of their efficacy,J Am Dent Assoc,2001,132(6):770～777.
[4] Pierce C J,Chrisman K,Bennett M E,et al,Stress,anticipatory stress,and psychologic measure related to sleep bruxism,J Orofac Pain,1995,9(1):51～56.
[5] Jorgic Srdjak K,Ivezic S,Cekic Arambasim A,et al,Bruxism and paychobiological model of personal,Coll Antropol,1998,22:205～212.
[6] Vanderas A P,Manetas K J,Relationship between malocclusion and bruxism in children and adolescents:a review,Pediatr Dent,1995,17(1):7～12.
[7] Macaluso. G M,Guerra P,Di Giovanni G et al,Sleep bruxism is a disorder related to periodic arousals during sleep,J Dent Rea,1998,77(4):565～573.
[8] Wise M E,Citalopram-induced bruxism,Br J Psychiatry,2001,178(2):182.
[9] Lobbezoo F,Soucy J P,Montplaisir J Y,et al,Striatal D2 receptor binding in sleep bruxism :a controlled study with iodine-123-iodobenzamide and single-photon-emission computed tomography,J Dent Res,1996,75(10):1804～1810.
[10]殷新民,张道珍,临床口腔医学杂志,2000,16(2):115～116.
[11] Tan E K,Jankovie J,Treating severe bruxism with botulinum toxin,J Am Dent Assoc,2000,131(2):211～216.
[12] Brown E S,Hong S C,Antidepressant-induced bruxism successfully treated with gabapentin,Journal of the American Dental Association,1999,130:1467～1469.
[13] Pryor JL,Kent-First M,Muallem A,et al,Microdeletion in the Ychromosome of infertile men,N Engl J Med,1997,336(8):534-539.
[14] Jattee M S,Bostwick J M,Buapirone as antidote to veolafaxine-included bruxism,Paychosomatics,2000,41(6):535～536.
[15] Rugh JD,Johnson RW,Temporal analysis of nocturnal bruxism during EMG feedback,J Periodontol,1981,52:263～265.
[16]符鹤,周忠华,蓝牙技术的原理及其应用,电脑应用技术,2006,67:40～51.
[17] NicolasRouhana,Horlait.,Bluetooth Web Internet Gateway,Proceedings of Seventh International Symposium on Computers and Communications,2002,7:679～684.
[18] David Johnson,Hardware and Software Implications of Creating Bluetooth Scatternet Devices,Africon Conference in Africa,2004,1:211～215.
[19] Glenford J.Myers,The art of software testing,New York,John Wiley sons,1979.
[20]李朝青,单片机原理及接口技术,北京:北京航空航天大学出版社,1994:58~60.
[21] Y. Amemori*,S. Yamashita*,M. Ai*,et al. Influence of nocturnal bruxism on the stomatognathic system PartⅠ:a new device for measuring mandibular movement during sleep,Journal of Oral Rehabilitation 2001,28:943～949.
[22] Lavigne,GJ,Romple PH,Montplaisir JY,Sleep brixsm:validity of clinical research diagnostic criteria in a controlled polysomngraphic study,Journal of Dental Research,75:546.
[23] Ikeda. T,Nishigawa. K,Criteria for the detection of sleep-associated bruxism in humans,Journal of Orofacial Pain,1996,10:270.
[24] Minagi. S,Akamatsu. T,Matsunaga. T,et al,Relationship between mandibular position and the coordination of masseter muscle activity during sleep in human,Journal of Oral Rehabilitation,1998,25:902.
[25] Ryuji Sakagami,Takeshi Horii,Shuichi Ino,et al,Development of a portable bruxism monitoring and analysis device equipped with a microcomputer and its practical application,Frontiers Med. Biol. Engng,2002,11(4):295～306.
[26] T. Kampe,G. Edman,G. Bader,et al,Personality traits in a group of subjects with long-standing bruxism behaviour,J. Oral Rehabil. 1997,24:588～593.
[27] R. Sakagami,H. Kato,Y. Tsuchida,I. Yoshida,et al,Development of automatic bruxism analysis system,Jpn. J. Conserv. Dent,2002,45:349~355.
[28] R. Ichiki,Y. Tsukiyama and K. Koyano,Development of a portable electromyographic recording device and an application for the evaluation of the day to day variation of nocturnal masseter muscle activity,J. Jpn. Soc. Stomatognath. Funct,1999,6:67～77.
[29] G. J. Lavine,P. H. Rpmpre,J. Y. Montplaisir,Sleep bruxism:validity of clinical research diagnostic criteria in a controlled polysomnographic study,J. Dent. Res,1996,77:546～552.
[30] C. P. Fernandes,L. B. Psarras,L. B. Freitas,et al,Jaw-closing muscles:electromyographic activity of human subjects with reduced periodontal support,J. Oral Rehab,1994,21:165～175.
[31] H. Hanamura,F. Houston and H. Rylander,Periodontal status and bruxism:a comparative study of patients with periodontal disease and occlusal parafunctions,J. Periodontol. 1987,58,173～176.
[32] Treacy K,Awareness/relaxation training and transcutaneous electrical neural stimulation in the treatment of bruxism,J Oral Rehabil,1999,26:280～287.
[33]张鸿懿,音乐疗法(一),中国自然医学杂志,1999,11:1～2.
[34]普凯元,音乐治疗的理论基础,医学与哲学,1991,(1):39.
[35] Holmegn K,Sheikholeslam A,Riise C,Effect of a full-arch maxillary occlusal splint on parafunctional activity during sleep in patients with nocturnal bruxism and sign and sympotoms of craniomandibular disorder,J Prosthet Dent,1993,69:293～297.
[36]刘迎春,叶湘滨,传感器原理设计与应用,北京:国防科技大学出版社,1997:107～121.
[37]于世风,口腔组织病理学,北京:人民卫生出版社,2000:9～11.
[38] Y. He,H Liang,The role of government in china’s healthcare IT Development,Harvard China Rev,2006,7(1):58.
[39] Pal A,Mbarika,Telemedicine diffusion in a developing Country:The case of India,IEEE Transactions on Information Technology in Biomedicine,2005,2005,9(1):59.
[40]曾庆勇,微弱信号检测,杭州:浙江大学出版社,1994:323～325.
[41] Zarcone VP, Sleep hygiene. In:Kryger MH,Roth T,Dement WC.Principles and practice of sleep medicine, 2nd ed. Philadelphia:WBSaunders,1994,542-546.
[42] Clark GT,Koyano K,Browne PA,Oral motor disorders in humans,J Calif Dent Assoc,1993,21:19～30.
[43] Watson TS,Effectiveness of arousal and arousal plus overcorrection to reduce nocturnal bruxism,J Behav Ther Exp Psychiatry,1993,24:181～185.
[44] Holmgren K,Sheikholeslam A,Riise C,Effect of a full-arch maxillary occlusal splint on parafunctional activity during sleep in patients with nocturnal bruxism and signs and symptoms of craniomandibular disorders,J Prosthet Dent,1993,69:293～297.
[45]孙建民,杨清梅,传感器技术,北京:清华大学出版社,2006:231～239.
[46]压电薄膜传感器技术(国际互联网版本),精量电子(深圳)有限公司,1998.
[47]金观昌,于淼,压电薄膜压力分布计算机测试系统研究,清华大学学报(自然科学版),1998,38(2):21～24.
[48]万建国,朱纪军,石立华,PVDF压电薄膜在结构监测中的应用初探,传感器学报,1998,1:18～24.
[49]罗志增,何发昌,用PVDF制作的触觉传感器,传感器技术,1997,16(3):1～4.
[50]邹建华,彭宽平,姜新桥,电工电子技术基础,武汉:华中科技大学出版社,2005:442.
[51] Choi YB,Krause,JS.Telemedicine in the USA: standardization through information management and technical applications,IEEE Communications Magazine,2006,44(4):41.
[52]张卉,王运栋,曲爱华,基于蓝牙的设备管理信息系统研究,微计算机信息,2005,36:119～121.
[53] Bluetooth SIG Specification of the Bluetooth System Core,Version 1.1,England Cambridge Siliconkadio Co. ,Ltd,2001.
[54] Bruce Eckel,Java编程思想(候捷),北京:机械工业出版社,1994:39.
[55] Andre N. Klingsheim,J2ME Bluetooth Programming,Department of Informatics University of Bergen,2004.
[56] Sense8 Corporation,World Tool Kit C++ Programming Guide,USA,Sense8 Corporation,1999:10.
[57] Watanabe T,Baba K,Yamagata K,et al,A vibratory stimulationbased inhibition system for nocturnal bruxism:a clinical report,J Prosthet Dent,2001,85:233～235.