不同的灌注量行尿动力检查结果对TURP手术的指导意义
|
摘要
目的:通过2种膀胱内灌注不同量生理盐水进行尿动力检查,比较其结果对经尿道前列腺电切手术的指导意义有何差异,以及两种不同的灌注量那种能更好的反映膀胱功能。方法:进行队列研究,将欲行尿动力检查并准备行经尿道前列腺汽化电切治疗的40例前列腺增生患者,随机分成两组,一组用200ml行膀胱灌注尿动力检查,另一组膀胱内灌注400ml行尿动力检查,将两组的结果进行统计学处理看是否存在差异,并将符合手术标准的患者行术前症状评分,手术治疗后再次行症状评分,比较两组不同的检查方法是否有临床意义。结果:将40例患者随机分成两组行尿动力检查,其中A组膀胱压和B组膀胱压经正态性检验:资料服从正态分布;经方差齐性检验得:F=4.035,P=0.052,知方差齐,故进行成组设计t检验:t=-2.839,P=0.007,有统计学差异。A和B组的逼尿肌压力进行成组设计t检验:t=-2.736,P=0.009,存在统计学差异。但术后的尿流率测定和I-PSS评分均在正常范围内,说明两种不同的尿动力检查方法虽然有统计学差异,但没有临床意义,只要在183-818ml(男性)这个灌注量行尿动力检查,能够反映膀胱的正常功能。由此我们得出另一结论,术前行尿动力检查功能正常的膀胱术后出现排尿困难,原因是多方面的,不仅有尿动学本身原因,还有其它原因,值得进一步探讨。结论:两种不同的灌注方法行尿动力检查结果虽然存在统计学差异,但均能反映正常的膀胱功能,这种差异应该是在正常值范围之上的差异。只要在只要在183～818ml(男性)这个灌注量行尿动力检查,能够反映膀胱的正常功能
Objective: Through two kinds of different bladder urine volume of normal saline to check the power, Comparing the results of transurethral resection of prostate surgery guide What's the difference, And two different perfusion that can better reflect the bladder function. Methods: Cohort study conducted, For power line will be checked and ready urine via vaporization resection of prostate TURP treatment of 40 cases of patients with benign prostatic hyperplasia, Randomly divided into two groups, One group of urinary bladder 200ml power line inspection, another group of bladder urine 400ml power line inspection, will be the results of two sets of statistical treatment to see if there are differences, and in line with the standard surgical patients with preoperative symptom score, line again after surgery for symptom score, compared two different methods of checking whether there is clinical significance. Results: 40 patients were randomly divided into two groups of urine power line inspection, one of A Group B Group bladder pressure and bladder pressure as test of normality: the information subject to normal distribution;by the homogeneity of variance test were: F=4.035, P=0.052, known to homogeneity, it carried out the design group t test: t=-2.839, P=0.007, there is statistical difference. A and B group detrusor pressure group designed t test: t=-2.736, P=0.009, significant differences exist. However, after the flow rate measured and I-PSS score were within the normal range on two different methods of urine examination power although there is significant difference, but no clinical significance, as long as at 183-818ml (men) of the perfusion urine power line inspection, can reflect the normal function of the bladder. From this we come to another conclusion, preoperative power line inspection function and normal urinary bladder after voiding difficulties arise for many reasons, not only have their own urine pharmacokinetic reasons, have other reasons, it is worth further exploration.Conclusion: Two different perfusion methods of power line urine test results despite significant difference, but could reflect the normal bladder function,such differences should be above the normal range at the difference. Just as long as the 183-818ml (men) of the perfusion urine power line inspection, can reflect the normal function of the bladder
Objective: Through two kinds of different bladder urine volume of normal saline to check the power, Comparing the results of transurethral resection of prostate surgery guide What's the difference, And two different perfusion that can better reflect the bladder function. Methods: Cohort study conducted, For power line will be checked and ready urine via vaporization resection of prostate TURP treatment of 40 cases of patients with benign prostatic hyperplasia, Randomly divided into two groups, One group of urinary bladder 200ml power line inspection, another group of bladder urine 400ml power line inspection, will be the results of two sets of statistical treatment to see if there are differences, and in line with the standard surgical patients with preoperative symptom score, line again after surgery for symptom score, compared two different methods of checking whether there is clinical significance. Results: 40 patients were randomly divided into two groups of urine power line inspection, one of A Group B Group bladder pressure and bladder pressure as test of normality: the information subject to normal distribution;by the homogeneity of variance test were: F=4.035, P=0.052, known to homogeneity, it carried out the design group t test: t=-2.839, P=0.007, there is statistical difference. A and B group detrusor pressure group designed t test: t=-2.736, P=0.009, significant differences exist. However, after the flow rate measured and I-PSS score were within the normal range on two different methods of urine examination power although there is significant difference, but no clinical significance, as long as at 183-818ml (men) of the perfusion urine power line inspection, can reflect the normal function of the bladder. From this we come to another conclusion, preoperative power line inspection function and normal urinary bladder after voiding difficulties arise for many reasons, not only have their own urine pharmacokinetic reasons, have other reasons, it is worth further exploration.Conclusion: Two different perfusion methods of power line urine test results despite significant difference, but could reflect the normal bladder function,such differences should be above the normal range at the difference. Just as long as the 183-818ml (men) of the perfusion urine power line inspection, can reflect the normal function of the bladder
引文
[1]吴阶平,主编.吴阶平泌尿外科学.济南:山东科学技术出版社, 2004,5:1187.
[2] Jacobsen SJ, Jacobsen DJ, Girman CJ, et al. Treatment for benign prostatic hyperplasia among community dwelling men:the olmsted County study of urinary symptoms and health status. Jurol, 1999, 162:1301-1306.
[3]熊恩庆,沈文浩,宋波,等.良性前列腺增生患者手术前后尿动力学检查的临床应用价值.中华泌尿外科杂志, 2005, 20(6):393~395.
[4]郭应禄,主编.前列腺增生及前列腺癌.北京:人民卫生出版社, 1998. 83~85.
[5]尚吉文,王剑华,朱跃龙,等. BPH手术前后尿动力学检查及其临床价值.临床泌尿外科杂志, 2005, 20(6):369~370.
[6] Wright EJ, Fang J, Metter EJ, et al. Prostate apecific antigen predicts the long-term risk of prostate enlargement:resules form the Baltimore Longitudinal Study of Aging. J Urol, 2002, 167:2484-2487.
[7] Roehrborn CG, Boyel P, Bergner D, et al. Serwm prostate-specific antigen and prostate volume predict longterm change in sympotoms and flow rate :Results of a 4-year randomized trial comparing finasteride versus placebo. Urology, 1999, 54:662-669.
[8] Djavan B, Nickel JC, de la Rosette J, et al. The view of BPH progression :results of an international survey. Eur Urol. 2002, 41:490-496.
[9]崔吉吉,尹鉴淳,张和平,等.压力-流率测定在诊断老年男性排尿困难中的意义.中华泌尿外科杂志, 2004, 25(9):592~595.
[10]刘志敏,郭骏,潘铁军.静态尿道压力测定在诊断老年BPH所致膀胱出口梗阻中的作用.临床外科杂志, 2003, 11(增刊):28~30.
[11]金锡御,宋波,主编.临床尿动力学.北京:人民卫生出版社, 2002. 230.
[12] Orandi A. Transurethral incision of prostate compared with transurethral resection of prostate in 132 matching cases[J]. JU rol, 1987, 138:810-815
[13] Deare KPJ, Debruyne FMJ, Moonen WA. Extended bladder neck incision for outflow obstruction in male patients[J]. Br J U rol, 1983, 55:225-228
[14]梅骅.关于进一步提高开放性前列腺切除术疗效的几点意见.中华泌尿外科杂志, 1997, 18B131.
[15]廖利民,石炳毅,梁春泉,等. P2Q图及A2G图诊断前列腺增生性膀胱出口梗阻.中华泌尿外科杂志, 1996, 17B746.
[16]邓春华,郑克立,梅骅.前列腺增生症引起的逼尿肌功能变化.中华泌尿外科杂志, 1997, 18B116.
[17]张祥华良性前列腺增生治疗指南/那彦群.中国泌尿外科疾病诊断治疗指南.北京:人民卫生出版社, 2006:25-26.
[18] Meigs JB, Barry MJ, Giovannucci E, et al. Incident rates and risk factors for acute urimary retention:the health professionals followup study. J Urol, 1999, 162:376-382.
[19] Turner Warwick R, Whiteside CG, Worth PHL, et al. A urody-namic review of clinical problems associated with bladder neck dysfunction and its treatment by endoscopic incision and tran strigonal posterior prostatectomy[J]. Br J U rol, 1973, 45:44-49
[20]田兆雄,张卫东,张思孝,等.前列腺增生症的发病情况调查及TURP与开放性手术治疗的比较[J].中华泌尿外科杂志, 1989, 10:37-40
[21]杨荣,蒋鹤鸣,安世源,等. 200例经尿道电切前列腺的初步讨论[J].中华泌尿外科杂志, 1988, 9:102-104
[22] Orandi A. Transurethral incision of prostate compared with transurethral resection of prostate in 132 matching cases[J]. JU rol, 1987, 138:810-815
[23] Deare KPJ, Debruyne FMJ, Moonen WA. Extended bladder neck incision for outflow obstruction in male patients[J]. Br J U rol, 1983, 55:225-228
[24] Vicente RJ, Sanchez MF, Polou RJ. Tansurethral incision in be-nign prostate hypertrophy[J]. Arch Esp U rol, 1994, 47:915-922
[25]柏骅.关于进一步提高开放性前列腺切除术后疗效的几点意见.中华泌尿外科杂志, 1997, 18∶131-133.
[26]张鹏,高庆忠,武治津.前列腺增生症术后疗效不良的尿动力学分析.现代泌尿外科, 2001, 6(4):14-16.
[27]张文涛,何朝宏,文建国,等.良性前列腺增生术后排尿困难的尿动力学分析.河南外科杂志, 2007, 13(2):1-2.
[28]武治津,高庆忠,吴克让,等.压力-流率测定在前列腺增生症手术适应证的作用.中华泌尿外科杂志, 1998, 16(9):285-287
[29]赵军,贺大林,刘润明,等.良性前列腺增生相关的膀胱痉挛病因分析及治疗.中华男科学杂志, 2005, 11(4):275-276
[30] Turner Warwick R, Whiteside CG, Worth PHL, et al. A urody-namic review of clinical problems associated with bladder neck dysfunction and its treatment by endoscopic incision and transtrigonal posterior prostatectomy[J]. Br J U rol, 1973, 45:44-49
[31]田兆雄,张卫东,张思孝,等.前列腺增生症的发病情况调查及TURP与开放性手术治疗的比较[J].中华泌尿外科杂志, 1989, 10:37-40
[32]杨荣,蒋鹤鸣,安世源,等. 200例经尿道电切前列腺的初步讨论[J].中华泌尿外科杂志, 1988, 9:102-104
[33] Orandi A. Transurethral incision of prostate compared with transurethral resection of prostate in 132 matching cases[J]. JU rol, 1987, 138:810-815
[34] Deare KPJ, Debruyne FMJ, Moonen WA. Extended bladder neckincision for outflow obstruction in male patients[J]. Br J U rol, 1983, 55:225-228
[35] Vicente RJ, Sanchez MF, Polou RJ. Tansurethral incision in be-nign prostate hypertrophy[J]. Arch Esp U rol, 1994, 47:915-922
[36] Denis L, Griffiths K, Khoury S, et al. Proceeding of the 2nd International Consultation on BPH. Plymouth, United King-dom, Health Publication, 1998.
[37] Barry MJ, Fowler FJ, O'Leary MP, et al. The American uro-logical association symptom index for benign prostatic hyper-plasia. J Urol, 1992, 148:1549-57.
[38] McConnell JD. Benign prostatic hyperplasia:treatment guide-lines and patient classification. Br J Urol, 1995, 76:29-46.
[39]张士青,潘惟昕,盛兴标,等.问卷短期复测的稳定性研究.中华泌尿外科杂志, 1998, 19:728-32.
[40] Barry MJ, Williford WO, Chang Y, et al. Benign prostatic hy-perplasia specific status measures in clinical research:how much change in the American Urological Association symp-tom index and the benign prostatic hyperplasia impact indexis perceptible to patients. J Urol, 1995, 154:1770-4.
[41]吉村亚希子,新美三由纪,大桥靖雄,等. International prostate symptom score.日泌尿会志, 1997, 88:1013-20.
[42] Luján M, Páez BA, Martín OE, et al. The validity of the IPSS questionnaire in a sample of 262 patients with benign pro-static hyperplasia. Arch Esp Uro, 1997, 50(8):847-53.
[43] Rodrigues Netto NJr, de Lima ML, de Andrade EF, et al. Latin American study on patient acceptance of the Interna-tional Prostate Symptom Score(IPSS)in the evaluation of symptomatic benign prostatic hyperplasia. Urology, 1997, 49(1):46-9.
[44]邵强,郭宇文,郭宏波,等. BPH患者对中文版IPSS理解能力的评估.中华泌尿外科杂志, 2001, 22:51-3.
[45] Netto NR Jr, de Lima ML. The influence of patient education level on the International Prostatic Symptom Score. J Urol, 1995, 154:97-9.
[46] Perrin P, Némoz C, Paparel P, et al. A modified IPSS score: value of a choice of qualitative answers. Prog Urol, 2006, 16:168-73.
[47]王东文,刘红耀,米振国,等.前列腺增生症的逼尿肌功能改变[J].中华泌尿外科杂志, 1998, 19:268一269.
[48]沈桂新.超声在前列腺疾病诊断及治疗中的应用现状[J].中国医学文摘,老年医学, 2007, 16(2):110一112.
[49]张小东主译.尿动力学[M].北京:人民卫生出版社, 1999.
[50]胡强达.前列腺增生症的诊断[J].中华泌尿外科杂志, 1999, 20(7):443.
[51]王东文双卫兵.良胜前列腺增生患者膀肤小梁化程度与尿动力学检查结果的相关性研究[J].中华泌尿外科杂志2004, 25(7):469-472
[52]孙光.良性前列腺增生症的诊断与治疗[J].实用老年医学2005, 19(4):176一178.
[53]陈清树,吴银锁,刘英发等.良性前列腺增生并逼尿肌功能障碍的尿动力学检查及其临床价值[J].中华泌尿外科杂志, 2002,23:279-280
[54]杨百强.尿动力学检查在评价良性前列腺增生症治疗中的作用[J].陕西医学杂志, 2005, 34(10):1308一1309.
[55]邱功阔,宋波,金锡御等.膀肤出口梗阻对逼尿肌兴奋性?收缩性及顺应性影响的实验研究[J].中华泌尿外科杂志, 2000, 21:4214.
[56]卢一平. BPH膀胧出口梗阻患者的逼尿肌功能状况评价[J].中华泌尿外科杂志, 1998,19:262.
[57] Ban’yMJ, FowlerFJ, O, learyMp, et al. TheAmerieanUrologiealAssoeiation sym PtomindexforbenignProstatehyPerplasia[J]. JUrol, 1992, 148:1549.
[66]孙忠全,宋建达.我国前列腺增生症腔内治疗的现状和进展[U].中国男科学杂志, 2003, 17(4):219
[67] elDinKE, deWildtMJ, RosierPF, etal. Thecorre lation between uronamie andeystose opiefindinginel derlymen with voidin geomplaints[J]. JUrol, 1996, 155(3):1018-1022.
[68]章振保.前列腺增生症的尿动力学改变[J].实用医学杂志, 2001, 17(1):8.
[69] Soliman SA, Wadie B S, Ibrahim el-HE, et al. Rotoresection versus transurethral resection of the prostate: short-term evaluation of a pro-spective randomized study[J]. JUro, l 2007, 177(3): 1036-1039.
[70]何有华,陈映鹤,竺海波,等.尿动力学检查在前列腺增生症术前评估中的临床意义[J].临床外科杂志, 2006, 14(6): 372-373.
[71] NeveusT, von-Gontard A, Hoebeke P, et al. The standardization of terminology of lower urinary tract function in children and adolescents: report from the Standardisation Committee of the InternationalChildren’s Continence Society[J]. JUro, l 2006, 176(1): 314-324.
[1] Mcconnel JD, Roehrborn CG, bautista OM, et al The long-term effect of doxazosin, finateride, and combination therapy on the clincial progression of benign prostatic hyerplasia. N Engl Med, 2003, 349:2387-2398.
[2] Madersbacher S, Alivizatos G, Nordling J, et al. EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction. Eur Urol, 2004, 46:547-554.
[3]张祥华良性前列腺增生治疗指南/那彦群.中国泌尿外科疾病诊断治疗指南.北京:人民卫生出版社, 2006:25-26.
[4] Jacobsen SJ, Jacobsen DJ, Girman CJ, et al. Treatment for benign prostatic hyperplasia among community dwelling men:the olmsted County study of urinary symptoms and health status. Jurol, 1999, 162:1301-1306.
[5] Meigs JB, Barry MJ, Giovannucci E, et al. Incident rates and risk factors for acute urimary retention:the health professionals followup study. J Urol, 1999, 162:376-382.
[6] Wright EJ, Fang J, Metter EJ, et al. Prostate apecific antigen predicts the long-term risk of prostate enlargement:resules form the Baltimore Longitudinal Study of Aging. J Urol, 2002, 167:2484-2487.
[7] Roehrborn CG, Boyel P, Bergner D, et al. Serwm prostate-specific antigen and prostate volume predict longterm change in sympotoms and flow rate :Results of a 4-year randomized trial comparing finasteride versus placebo. Urology, 1999, 54:662-669.
[8] Djavan B, Nickel JC, de la Rosette J, et al. The view of BPH progression :results of an international survey. Eur Urol. 2002, 41:490-496.
[9]王国民,徐伟刚,上海市区良性前列腺增生症危险因素调查,中华预防医学杂志, 1997 10:107-108.
[10] McNicholas T, LUTS, the case is altered. Eur Urol, 2002, 9(Suppl):28-35
[11] Roberts RO, Jacobsen SJ, Rhodes T, et al. Longititudinal changes in peak urinary flow rates in a communitybased cohort. J Urol, 2000, 163:107-113.
[12] Roehrborn CG, MConnell JD, Lieber M, et al. serum prostate-specific antigen is a powerfull predictor of acute urinary retent on and the need for surgery in men with clinical benign prostatic hyperplasia. Urology, 1999, 53:473-480.
[13] McConnell JD, Bruskewitz R, Walsh P, et al. The effect of finasteride on the risk of acute urinary retention and the need for surgical treatment among men with benignprostatic hyperplasia. Finasteride Long-Term Efficacy and safety Study Group. N Engl J Med, 1998, 338:557-663.
[14]刘海红,夏欣一,黄宇烽?慢性前列腺炎与细胞因子研究进展.中华男科学杂志2006, 12(6):548-550
[15]张矩,陈林峰,祝韶军,等?性激素受体及相关因子在前列腺基质细胞中的表达.临床泌尿外科杂志, 2002, 17(8):417-419.
[2] Jacobsen SJ, Jacobsen DJ, Girman CJ, et al. Treatment for benign prostatic hyperplasia among community dwelling men:the olmsted County study of urinary symptoms and health status. Jurol, 1999, 162:1301-1306.
[3]熊恩庆,沈文浩,宋波,等.良性前列腺增生患者手术前后尿动力学检查的临床应用价值.中华泌尿外科杂志, 2005, 20(6):393~395.
[4]郭应禄,主编.前列腺增生及前列腺癌.北京:人民卫生出版社, 1998. 83~85.
[5]尚吉文,王剑华,朱跃龙,等. BPH手术前后尿动力学检查及其临床价值.临床泌尿外科杂志, 2005, 20(6):369~370.
[6] Wright EJ, Fang J, Metter EJ, et al. Prostate apecific antigen predicts the long-term risk of prostate enlargement:resules form the Baltimore Longitudinal Study of Aging. J Urol, 2002, 167:2484-2487.
[7] Roehrborn CG, Boyel P, Bergner D, et al. Serwm prostate-specific antigen and prostate volume predict longterm change in sympotoms and flow rate :Results of a 4-year randomized trial comparing finasteride versus placebo. Urology, 1999, 54:662-669.
[8] Djavan B, Nickel JC, de la Rosette J, et al. The view of BPH progression :results of an international survey. Eur Urol. 2002, 41:490-496.
[9]崔吉吉,尹鉴淳,张和平,等.压力-流率测定在诊断老年男性排尿困难中的意义.中华泌尿外科杂志, 2004, 25(9):592~595.
[10]刘志敏,郭骏,潘铁军.静态尿道压力测定在诊断老年BPH所致膀胱出口梗阻中的作用.临床外科杂志, 2003, 11(增刊):28~30.
[11]金锡御,宋波,主编.临床尿动力学.北京:人民卫生出版社, 2002. 230.
[12] Orandi A. Transurethral incision of prostate compared with transurethral resection of prostate in 132 matching cases[J]. JU rol, 1987, 138:810-815
[13] Deare KPJ, Debruyne FMJ, Moonen WA. Extended bladder neck incision for outflow obstruction in male patients[J]. Br J U rol, 1983, 55:225-228
[14]梅骅.关于进一步提高开放性前列腺切除术疗效的几点意见.中华泌尿外科杂志, 1997, 18B131.
[15]廖利民,石炳毅,梁春泉,等. P2Q图及A2G图诊断前列腺增生性膀胱出口梗阻.中华泌尿外科杂志, 1996, 17B746.
[16]邓春华,郑克立,梅骅.前列腺增生症引起的逼尿肌功能变化.中华泌尿外科杂志, 1997, 18B116.
[17]张祥华良性前列腺增生治疗指南/那彦群.中国泌尿外科疾病诊断治疗指南.北京:人民卫生出版社, 2006:25-26.
[18] Meigs JB, Barry MJ, Giovannucci E, et al. Incident rates and risk factors for acute urimary retention:the health professionals followup study. J Urol, 1999, 162:376-382.
[19] Turner Warwick R, Whiteside CG, Worth PHL, et al. A urody-namic review of clinical problems associated with bladder neck dysfunction and its treatment by endoscopic incision and tran strigonal posterior prostatectomy[J]. Br J U rol, 1973, 45:44-49
[20]田兆雄,张卫东,张思孝,等.前列腺增生症的发病情况调查及TURP与开放性手术治疗的比较[J].中华泌尿外科杂志, 1989, 10:37-40
[21]杨荣,蒋鹤鸣,安世源,等. 200例经尿道电切前列腺的初步讨论[J].中华泌尿外科杂志, 1988, 9:102-104
[22] Orandi A. Transurethral incision of prostate compared with transurethral resection of prostate in 132 matching cases[J]. JU rol, 1987, 138:810-815
[23] Deare KPJ, Debruyne FMJ, Moonen WA. Extended bladder neck incision for outflow obstruction in male patients[J]. Br J U rol, 1983, 55:225-228
[24] Vicente RJ, Sanchez MF, Polou RJ. Tansurethral incision in be-nign prostate hypertrophy[J]. Arch Esp U rol, 1994, 47:915-922
[25]柏骅.关于进一步提高开放性前列腺切除术后疗效的几点意见.中华泌尿外科杂志, 1997, 18∶131-133.
[26]张鹏,高庆忠,武治津.前列腺增生症术后疗效不良的尿动力学分析.现代泌尿外科, 2001, 6(4):14-16.
[27]张文涛,何朝宏,文建国,等.良性前列腺增生术后排尿困难的尿动力学分析.河南外科杂志, 2007, 13(2):1-2.
[28]武治津,高庆忠,吴克让,等.压力-流率测定在前列腺增生症手术适应证的作用.中华泌尿外科杂志, 1998, 16(9):285-287
[29]赵军,贺大林,刘润明,等.良性前列腺增生相关的膀胱痉挛病因分析及治疗.中华男科学杂志, 2005, 11(4):275-276
[30] Turner Warwick R, Whiteside CG, Worth PHL, et al. A urody-namic review of clinical problems associated with bladder neck dysfunction and its treatment by endoscopic incision and transtrigonal posterior prostatectomy[J]. Br J U rol, 1973, 45:44-49
[31]田兆雄,张卫东,张思孝,等.前列腺增生症的发病情况调查及TURP与开放性手术治疗的比较[J].中华泌尿外科杂志, 1989, 10:37-40
[32]杨荣,蒋鹤鸣,安世源,等. 200例经尿道电切前列腺的初步讨论[J].中华泌尿外科杂志, 1988, 9:102-104
[33] Orandi A. Transurethral incision of prostate compared with transurethral resection of prostate in 132 matching cases[J]. JU rol, 1987, 138:810-815
[34] Deare KPJ, Debruyne FMJ, Moonen WA. Extended bladder neckincision for outflow obstruction in male patients[J]. Br J U rol, 1983, 55:225-228
[35] Vicente RJ, Sanchez MF, Polou RJ. Tansurethral incision in be-nign prostate hypertrophy[J]. Arch Esp U rol, 1994, 47:915-922
[36] Denis L, Griffiths K, Khoury S, et al. Proceeding of the 2nd International Consultation on BPH. Plymouth, United King-dom, Health Publication, 1998.
[37] Barry MJ, Fowler FJ, O'Leary MP, et al. The American uro-logical association symptom index for benign prostatic hyper-plasia. J Urol, 1992, 148:1549-57.
[38] McConnell JD. Benign prostatic hyperplasia:treatment guide-lines and patient classification. Br J Urol, 1995, 76:29-46.
[39]张士青,潘惟昕,盛兴标,等.问卷短期复测的稳定性研究.中华泌尿外科杂志, 1998, 19:728-32.
[40] Barry MJ, Williford WO, Chang Y, et al. Benign prostatic hy-perplasia specific status measures in clinical research:how much change in the American Urological Association symp-tom index and the benign prostatic hyperplasia impact indexis perceptible to patients. J Urol, 1995, 154:1770-4.
[41]吉村亚希子,新美三由纪,大桥靖雄,等. International prostate symptom score.日泌尿会志, 1997, 88:1013-20.
[42] Luján M, Páez BA, Martín OE, et al. The validity of the IPSS questionnaire in a sample of 262 patients with benign pro-static hyperplasia. Arch Esp Uro, 1997, 50(8):847-53.
[43] Rodrigues Netto NJr, de Lima ML, de Andrade EF, et al. Latin American study on patient acceptance of the Interna-tional Prostate Symptom Score(IPSS)in the evaluation of symptomatic benign prostatic hyperplasia. Urology, 1997, 49(1):46-9.
[44]邵强,郭宇文,郭宏波,等. BPH患者对中文版IPSS理解能力的评估.中华泌尿外科杂志, 2001, 22:51-3.
[45] Netto NR Jr, de Lima ML. The influence of patient education level on the International Prostatic Symptom Score. J Urol, 1995, 154:97-9.
[46] Perrin P, Némoz C, Paparel P, et al. A modified IPSS score: value of a choice of qualitative answers. Prog Urol, 2006, 16:168-73.
[47]王东文,刘红耀,米振国,等.前列腺增生症的逼尿肌功能改变[J].中华泌尿外科杂志, 1998, 19:268一269.
[48]沈桂新.超声在前列腺疾病诊断及治疗中的应用现状[J].中国医学文摘,老年医学, 2007, 16(2):110一112.
[49]张小东主译.尿动力学[M].北京:人民卫生出版社, 1999.
[50]胡强达.前列腺增生症的诊断[J].中华泌尿外科杂志, 1999, 20(7):443.
[51]王东文双卫兵.良胜前列腺增生患者膀肤小梁化程度与尿动力学检查结果的相关性研究[J].中华泌尿外科杂志2004, 25(7):469-472
[52]孙光.良性前列腺增生症的诊断与治疗[J].实用老年医学2005, 19(4):176一178.
[53]陈清树,吴银锁,刘英发等.良性前列腺增生并逼尿肌功能障碍的尿动力学检查及其临床价值[J].中华泌尿外科杂志, 2002,23:279-280
[54]杨百强.尿动力学检查在评价良性前列腺增生症治疗中的作用[J].陕西医学杂志, 2005, 34(10):1308一1309.
[55]邱功阔,宋波,金锡御等.膀肤出口梗阻对逼尿肌兴奋性?收缩性及顺应性影响的实验研究[J].中华泌尿外科杂志, 2000, 21:4214.
[56]卢一平. BPH膀胧出口梗阻患者的逼尿肌功能状况评价[J].中华泌尿外科杂志, 1998,19:262.
[57] Ban’yMJ, FowlerFJ, O, learyMp, et al. TheAmerieanUrologiealAssoeiation sym PtomindexforbenignProstatehyPerplasia[J]. JUrol, 1992, 148:1549.
[66]孙忠全,宋建达.我国前列腺增生症腔内治疗的现状和进展[U].中国男科学杂志, 2003, 17(4):219
[67] elDinKE, deWildtMJ, RosierPF, etal. Thecorre lation between uronamie andeystose opiefindinginel derlymen with voidin geomplaints[J]. JUrol, 1996, 155(3):1018-1022.
[68]章振保.前列腺增生症的尿动力学改变[J].实用医学杂志, 2001, 17(1):8.
[69] Soliman SA, Wadie B S, Ibrahim el-HE, et al. Rotoresection versus transurethral resection of the prostate: short-term evaluation of a pro-spective randomized study[J]. JUro, l 2007, 177(3): 1036-1039.
[70]何有华,陈映鹤,竺海波,等.尿动力学检查在前列腺增生症术前评估中的临床意义[J].临床外科杂志, 2006, 14(6): 372-373.
[71] NeveusT, von-Gontard A, Hoebeke P, et al. The standardization of terminology of lower urinary tract function in children and adolescents: report from the Standardisation Committee of the InternationalChildren’s Continence Society[J]. JUro, l 2006, 176(1): 314-324.
[1] Mcconnel JD, Roehrborn CG, bautista OM, et al The long-term effect of doxazosin, finateride, and combination therapy on the clincial progression of benign prostatic hyerplasia. N Engl Med, 2003, 349:2387-2398.
[2] Madersbacher S, Alivizatos G, Nordling J, et al. EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction. Eur Urol, 2004, 46:547-554.
[3]张祥华良性前列腺增生治疗指南/那彦群.中国泌尿外科疾病诊断治疗指南.北京:人民卫生出版社, 2006:25-26.
[4] Jacobsen SJ, Jacobsen DJ, Girman CJ, et al. Treatment for benign prostatic hyperplasia among community dwelling men:the olmsted County study of urinary symptoms and health status. Jurol, 1999, 162:1301-1306.
[5] Meigs JB, Barry MJ, Giovannucci E, et al. Incident rates and risk factors for acute urimary retention:the health professionals followup study. J Urol, 1999, 162:376-382.
[6] Wright EJ, Fang J, Metter EJ, et al. Prostate apecific antigen predicts the long-term risk of prostate enlargement:resules form the Baltimore Longitudinal Study of Aging. J Urol, 2002, 167:2484-2487.
[7] Roehrborn CG, Boyel P, Bergner D, et al. Serwm prostate-specific antigen and prostate volume predict longterm change in sympotoms and flow rate :Results of a 4-year randomized trial comparing finasteride versus placebo. Urology, 1999, 54:662-669.
[8] Djavan B, Nickel JC, de la Rosette J, et al. The view of BPH progression :results of an international survey. Eur Urol. 2002, 41:490-496.
[9]王国民,徐伟刚,上海市区良性前列腺增生症危险因素调查,中华预防医学杂志, 1997 10:107-108.
[10] McNicholas T, LUTS, the case is altered. Eur Urol, 2002, 9(Suppl):28-35
[11] Roberts RO, Jacobsen SJ, Rhodes T, et al. Longititudinal changes in peak urinary flow rates in a communitybased cohort. J Urol, 2000, 163:107-113.
[12] Roehrborn CG, MConnell JD, Lieber M, et al. serum prostate-specific antigen is a powerfull predictor of acute urinary retent on and the need for surgery in men with clinical benign prostatic hyperplasia. Urology, 1999, 53:473-480.
[13] McConnell JD, Bruskewitz R, Walsh P, et al. The effect of finasteride on the risk of acute urinary retention and the need for surgical treatment among men with benignprostatic hyperplasia. Finasteride Long-Term Efficacy and safety Study Group. N Engl J Med, 1998, 338:557-663.
[14]刘海红,夏欣一,黄宇烽?慢性前列腺炎与细胞因子研究进展.中华男科学杂志2006, 12(6):548-550
[15]张矩,陈林峰,祝韶军,等?性激素受体及相关因子在前列腺基质细胞中的表达.临床泌尿外科杂志, 2002, 17(8):417-419.