祛痰除湿化瘀法治疗痰湿瘀结型子宫肌瘤的临床疗效观察
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摘要
目的：系统观察祛痰除湿化瘀法治疗子宫肌瘤痰湿瘀结型的临床疗效。
方法：用自拟祛痰除湿化瘀方对56例子宫肌瘤痰湿瘀结型患者进行治疗,每一个月为一个疗程,连续观察三个疗程。每疗程结束时,观察患者症状积分、肌瘤大小及子宫大小的变化。疗程结束后,用SPSS13.0软件对积分进行统计学分析,判定疗效。
结果：祛痰除湿化瘀方对患者疗效分别为：中医症候疗效显效率30.36%、有效率为58.93%,总有效率89.29%；对肌瘤疗效痊愈率为5.36%、显效率为8.93%、有效率为39.28%,总有效率为53.57%。总综合有效率为55.35%。
结论：说明本方对患者肌瘤大小的改善不明显,但是在改善患者临床症状,减轻痛苦方面有明显疗效,有临床推广价值。
Objective:to observe the clinical effection of expelling phlegm dispersing dampness and resolving blood stasis method applied in the treatment of uterine myoma which belongs to phlegm acuminated with blood stasis.
Methods:56 cases of uterine myoma which belongs to phlegm acuminated with blood stasis were treated by the formula named qutanchushihuayu fang. Take one month as a treatment course and observe the changes of the symptoms continuously for three treatment courses. To record the changes of symptoms、volume of uterus and size of the myoma in scores after each treatment course. To anlyse the scores with software SPSS 13.0 and judge the effection of the treatment.
Results:tatally,89.29% of the patients'symptoms are inproved, and 46.43% of the patients'myoma are smaller than before treatment. The total effection of this treatment is 53.57%.The tatal effective proption of treatment effection including both symptoms and volmum of myoma is 55.35%. The effection of this formula of improving the symptoms is more obvious than the effection of smaller the size of myoma. It is valuable for the widening use of this formula to improve the symptoms.
Conclusion:As to uterine myoma which belongs to phlegm acuminated with blood stasis, this formula has very obvious effection for inproveing the symptoms of the patients to release their tourch of the disease.It is vualuable for clinic application.
方法：用自拟祛痰除湿化瘀方对56例子宫肌瘤痰湿瘀结型患者进行治疗,每一个月为一个疗程,连续观察三个疗程。每疗程结束时,观察患者症状积分、肌瘤大小及子宫大小的变化。疗程结束后,用SPSS13.0软件对积分进行统计学分析,判定疗效。
结果：祛痰除湿化瘀方对患者疗效分别为：中医症候疗效显效率30.36%、有效率为58.93%,总有效率89.29%；对肌瘤疗效痊愈率为5.36%、显效率为8.93%、有效率为39.28%,总有效率为53.57%。总综合有效率为55.35%。
结论：说明本方对患者肌瘤大小的改善不明显,但是在改善患者临床症状,减轻痛苦方面有明显疗效,有临床推广价值。
Objective:to observe the clinical effection of expelling phlegm dispersing dampness and resolving blood stasis method applied in the treatment of uterine myoma which belongs to phlegm acuminated with blood stasis.
Methods:56 cases of uterine myoma which belongs to phlegm acuminated with blood stasis were treated by the formula named qutanchushihuayu fang. Take one month as a treatment course and observe the changes of the symptoms continuously for three treatment courses. To record the changes of symptoms、volume of uterus and size of the myoma in scores after each treatment course. To anlyse the scores with software SPSS 13.0 and judge the effection of the treatment.
Results:tatally,89.29% of the patients'symptoms are inproved, and 46.43% of the patients'myoma are smaller than before treatment. The total effection of this treatment is 53.57%.The tatal effective proption of treatment effection including both symptoms and volmum of myoma is 55.35%. The effection of this formula of improving the symptoms is more obvious than the effection of smaller the size of myoma. It is valuable for the widening use of this formula to improve the symptoms.
Conclusion:As to uterine myoma which belongs to phlegm acuminated with blood stasis, this formula has very obvious effection for inproveing the symptoms of the patients to release their tourch of the disease.It is vualuable for clinic application.
引文
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[9]鲁西″脑45增强扫描应用姜半夏预防造影剂副作用[J].中国中西医结合杂志,1992,12(5)：299.
[10]黄春林,朱晓新主编.中药药理与临床手册,人民卫生出版社,2006,第1版：558.559.
[11]张明发等苍术药理研究[J].1999年第10卷第1期
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[13]沈丕安主编.中药药理与临床运用,人民卫生出版社,2006,第1版：476-477
[14]沈丕安主编.中药药理与临床运用,人民卫生出版社,2006,第1版：203-205
[15]黄春林,朱晓新主编.中药药理与Ⅰ临床手册,人民卫生出版社,2006,第1版：291-292
[16]石宏志.泽兰对血液流变学影响的研究与进展[J].中国临床康复,2004,81341：7776-7
[17]宋树立.川牛膝水煎液小鼠妊娠的实验研究[J].中国医药学,1998,10(3)：22.
[18]水平,李新华,孙曙光.怀牛膝的药理研究续报[J].河南中医,1985,5(1)：40.
[19]马亚兵.枳壳的胃肠作用及炮制前后的变化[J].中药药理与临床,1996,16(6)：28.
[20]宿树兰.枳壳的研究进展[J].中药材.2001,24(3)
[21]易明娟.宫宁口服液治疗子宫肌瘤的实验研究.中药药理与临床,1996,12(4)：41-43
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[23]Parker WH, Fu YS, Berek JS. Uterine sarcoma in patients operated on for presumed leiomyoma and rapid growing leiomyoma. Obstet Gynecol [M]1994,83:414-418
[24]Vikhlyaeva EM. Khedzh va zs, Fantsebenko ND. et.al. Faminail predisposition to uterine leiomyoms. Int J Gynaecol Obstet.1995.51(2): 127
[25]Mmhall LM. Spiegel-D. Barbieri RL. Et. D. Variation in the incidence of uterine leiomyoma among pmmenopausal women by age andmObstet Gynee01.1997,90(6):967
[26]HeinemannK, ThielC, Mohneretal, Benigngy necologicaltumors: estimated incidence. Resultsof the German Cohort Studyon Women, Health. German Cohort Study on WomenHealth[J]. EurJObstetGynecol ReProdBi01.2003,26:107(1):78-80.
[27]Quade BJ,Weremowicz S,Neskey D M。et al.Fuision transcripts involving HMGA2 are not a common molecular mechanism in uterine leiomyomata rearrangements in 12ql5[J]. Cancer Res.2003,63(6):1351
[28]Williams A J, Ponell W I.. Collins T。et al. Clinical Significance of cytogenetie abnormalities in uterine myomas[J]. Am J Path,1997,150: 911
[29]Kriss S. Clinical significance of cytogenetlc abnormalities in utetine myomas[J]. Cancer Genet Cytogenets,1999,114:9
[30]Kazmierezak B, Paltin P, Wanschura S。et al. Chlinical significance of cytogenetic abnormalities in uterine myomas[J]. Genes Chromosomes Cancer.1998.23(4):279.285
[31]史金凤.子宫肌瘤的病因及发病机理研究进展孙忠实[J].实用妇产科杂志,2001,28(1)：17,
[32]Del.O V. Morgant Gterine fibromas and the hormonal paRem, [J]the Peutiee considerations MinervaGine01.1996:48:533
[33]Brandon DD, Efickson TE, Keenan EJ; et al. Estrogen receptor gene expression in human uterine leiomata,[J]Clin Endocrinol Metab.1995, 80:1876
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