银翘散加减方联合窄谱中波紫外线治疗玫瑰糠疹临床疗效观察
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摘要
玫瑰糠疹是一种临床常见的皮肤病,目前病因不明。其临床表现为先出现一上覆细小鳞屑的圆形或椭圆形红色斑疹,即“母斑”,1—2周后,渐在躯干及四肢近端出现多数形态相似的小斑疹,即“子斑”,其长轴与皮纹走向一致,呈对称分布。其发病率较高。目前现代医学常使用抗组胺药配合外用药物,或使用免疫调节剂、抗生素等治疗。物理疗法有紫外线光照疗法、高压氧治疗等。但尚没有一种公认有效的治疗方法。中医药治疗本病历史悠久,积累了丰富的临床经验,具有疗效较好,副作用较小的优势;同时存在着个体差异明显等缺点。本研究运用中医基本理论,结合现代医学技术,从临床表现综合评分观察中医药治疗玫瑰糠疹的临床疗效,并为其提供科学依据,有一定的理论及实际意义。
目的:观察银翘散加减方联合窄谱中波紫外线治疗玫瑰糠疹的临床疗效
方法:42例玫瑰糠疹患者随机分成治疗组和对照组。治疗组20例,口服银翘散加减方,外用解毒搽剂,结合皮疹局部窄谱中波紫外线照射治疗;对照组22例,口服盐酸西替利嗪片,外治法同治疗组。采用PRSS积分观察治疗前后患者皮损的变化。并记录患者出现的任何不良反应。
结果:银翘散加减方治疗组在改善PRSS积分、有效率、安全性及时效性方面均优于西替利嗪对照组,差异均具有显著性意义(P＜0.05)。
结论:银翘散加减方治疗玫瑰糠疹临床疗效明显,优于西替利嗪。
Pityriasis rosea is a common erythroderma desquamativum disease, of which the origin is currently unknown. It is liable to attack the torso and areas near the end of the limbs. It is purple in colour and covered with scales,the long axis of the macular eruption being parallel to that of the skin. At first, an erythema, which is termed mother erythema,appears at a certain place on the torso or oval shape. 1 ~ 2 weeks later, in other places, the same macula eruption, smaller than the mother erythema and of different sizes, called child erythema, appear in groups one after another. They are usually arranged in a symmetrical manner. Its incidence is high. At present the modern medicine often uses the antihistamine coordination external use, or uses immunity conditioner, antibiotic. The physiotherapy includs the ultraviolet ray illumination therapy, the high pressure oxygen treatment and so on. But still there is no recognized effective treatment. TCM treatment of this disease has a long history, has accumulated rich clinical experience, with the advantages of better efficacy and less side effects; At the same time there is a disadvantage, such as individual differences. In this study, the use of the basic theory of traditional Chinese medicine combined with modern medical technology, from clinical observation of the performance of General score pityriasis rosea in Chinese medicine the treatment of clinical efficacy, and provide a scientific basis, there is a theoretical and practical significance.
Objectives: To observe the clinical efficacy Powder Yinqiao Combined With Narrow Band UVB on Treating Pityriasis Rosea.
Methods: 42 cases of pityriasis rosea were randomly divided into treatment group and the control group. Treatment group 20 cases, oral Powder Yinqiao side Jiedu liniment for external use, combined with a rash of local narrow-band UVB irradiation; 22 cases of the control group, oral cetirizine hydrochloride tablets, use the same external treatment with the treatment group. PRSS points used before and after the skin lesions of patients with treatment changes. And recorded any adverse reactions.
Results: Powder Yinqiao side is superior to the control group with in improving the treatment group at PRSS points, the efficiency, safety and timeliness. The differences are significant.
Conclusion: Powder Yinqiao side effects clinical treatment of pityriasis rosea significantly better than cetirizine.
目的:观察银翘散加减方联合窄谱中波紫外线治疗玫瑰糠疹的临床疗效
方法:42例玫瑰糠疹患者随机分成治疗组和对照组。治疗组20例,口服银翘散加减方,外用解毒搽剂,结合皮疹局部窄谱中波紫外线照射治疗;对照组22例,口服盐酸西替利嗪片,外治法同治疗组。采用PRSS积分观察治疗前后患者皮损的变化。并记录患者出现的任何不良反应。
结果:银翘散加减方治疗组在改善PRSS积分、有效率、安全性及时效性方面均优于西替利嗪对照组,差异均具有显著性意义(P＜0.05)。
结论:银翘散加减方治疗玫瑰糠疹临床疗效明显,优于西替利嗪。
Pityriasis rosea is a common erythroderma desquamativum disease, of which the origin is currently unknown. It is liable to attack the torso and areas near the end of the limbs. It is purple in colour and covered with scales,the long axis of the macular eruption being parallel to that of the skin. At first, an erythema, which is termed mother erythema,appears at a certain place on the torso or oval shape. 1 ~ 2 weeks later, in other places, the same macula eruption, smaller than the mother erythema and of different sizes, called child erythema, appear in groups one after another. They are usually arranged in a symmetrical manner. Its incidence is high. At present the modern medicine often uses the antihistamine coordination external use, or uses immunity conditioner, antibiotic. The physiotherapy includs the ultraviolet ray illumination therapy, the high pressure oxygen treatment and so on. But still there is no recognized effective treatment. TCM treatment of this disease has a long history, has accumulated rich clinical experience, with the advantages of better efficacy and less side effects; At the same time there is a disadvantage, such as individual differences. In this study, the use of the basic theory of traditional Chinese medicine combined with modern medical technology, from clinical observation of the performance of General score pityriasis rosea in Chinese medicine the treatment of clinical efficacy, and provide a scientific basis, there is a theoretical and practical significance.
Objectives: To observe the clinical efficacy Powder Yinqiao Combined With Narrow Band UVB on Treating Pityriasis Rosea.
Methods: 42 cases of pityriasis rosea were randomly divided into treatment group and the control group. Treatment group 20 cases, oral Powder Yinqiao side Jiedu liniment for external use, combined with a rash of local narrow-band UVB irradiation; 22 cases of the control group, oral cetirizine hydrochloride tablets, use the same external treatment with the treatment group. PRSS points used before and after the skin lesions of patients with treatment changes. And recorded any adverse reactions.
Results: Powder Yinqiao side is superior to the control group with in improving the treatment group at PRSS points, the efficiency, safety and timeliness. The differences are significant.
Conclusion: Powder Yinqiao side effects clinical treatment of pityriasis rosea significantly better than cetirizine.
引文
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