PM_(2.5)污染与低出生体重发生风险关联的研究进展
|
摘要
PM_(2.5)指环境空气中直径小于或等于2.5微米的颗粒物,可以通过呼吸道等途径进入人体,并诱发氧化应激和炎症反应。研究显示,空气污染与低出生体重、早产、宫内发育迟缓等不良妊娠结局存在关联。本文主要就大气污染物PM_(2.5)与低出生体重发生风险的关联研究进行综述,以期为今后流行病学研究及发生机制研究提供参考。
引文
1联合国儿童基金会.2016年世界儿童状况报告.2016.
2 Wardlaw T,Blanc A,Zupan J,et al.Low birth weight:country regional and global estimates.New York:UNICEF,2004.
3卫生部.中国妇女发展纲要(2011-2020年).
4卫生部.中国儿童发展纲要(2011-2020年).
5 Starzec K,Klimek M,GrudzieńA,et al.Longitudinal assessment of renal size and function in extremely low birth weight children at 7and 11 years of age.Pediatr Nephrol,2016,31:2119-2126.
6 Barker DJ.The fetal origins of coronary heart disease.Eur Heart J,1997,18:883-884.
7 Barker DJ.The fetal and infant origins of adult disease.BMJ,1990,301:1111.
8 Barker D,Eriksson JG,Forsén T,et al.Fetal origins of adult disease:strength of effects and biological basis.Int J Epidemiol,2002,31:1235-1239.
9邵肖梅.成人疾病胎儿起源相关问题---追赶生长的利与弊.中华围产医学杂志,2012,15:129-131.
10 Kelishadi R,Haghdoost AA,Jamshidi F,et al.Low birthweight or rapid catch-up growth:which is more associated with cardiovascular disease and its risk factors in later life?A systematic review and cryptanalysis.Paediatr Int Child Health,2015,35:110-123.
11 Alves JG,Vasconcelos SA,de Almeida TS,et al.Influence of catchup growth on abdominal fat distribution in very low birth weight children-cohort study.J Pediatr Endocr Met,2015,28:153-156.
12 Liu S,Krewski D,Shi Y,et al.Association between maternal exposure to ambient air pollutants during pregnancy and fetal growth restriction.J Expo Sci Environ Epidemiol,2007,17:426-432.
13 Ritz B,Yu F,Fruin S,et al.Ambient Air Pollution and Risk of Birth Defects in Southern California.Am J Epidemiol,2002,155:17-25.
14 Bobak M.Outdoor air pollution,low birth weight,and prematurity.Environ Health Perspect,2000,108:173-176.
15 van den Hooven EH,Pierik FH,de Kluizenaar Y,et al.Air pollution exposure and markers of placental growth and function:the generation R Study.Environ Health Perspect,2012,120:1753-1759.
16 Li X,Huang S,Jiao A,et al.Association between ambient fine particulate matter and preterm birth or term low birth weight:An updated systematic review and meta-analysis.Environ Pollut,2017,227:596-605.
17 Geer L A,Weedon J,Bell M L.Ambient air pollution and term birth weight in Texas from 1998 to 2004.J Air Waste Manage,2012,62:1285-1295.
18 Fleischer NL.Outdoor air pollution,preterm birth,and low birth weight:analysis of the world health organization global survey on maternal and perinatal health.Environ Health Perspect,2014,122:425-430.
19张燕萍,刘旭辉,任展宏,等.太原市大气污染对妊娠结局的影响.环境与健康杂志,2007,24:128-131.
20 Zhao Y,Chen X,Liu X,et al.Exposure of mice to benzo(a)pyrene impairs endometrial receptivity and reduces the number of implantation sites during early pregnancy.Food Chem Toxicol,2014,69:244-251.
21 Talbot P,Lin S.The effect of cigarette smoke on fertilization and preimplantation development:assessment using animal models,clinical data,and stem cells.Biol Res,2011,44:189-194.
22 Ritz B,Yu F,Chapa G,et al.Effect of air pollution on preterm birth among children born in southern California between 1989 and 1993.Epidemiology,2000,11:502-511.
23 Medeiros A.Relationship between low birthweight and air pollution in the city of Sao Paulo,Brazil.Revista De Saude Publica,2005,39:965-972.
24 Dugandzic R,Dodds L,Stieb D,et al.The association between low level exposures to ambient air pollution and term low birth weight:a retrospective cohort study.Evniron Health,2006,5:3-10.
25王双青,王艳梅,董淑英,等.孕期PM2.5暴露与新生儿生长发育关系的初步研究.环境与健康杂志,2014,31:163-166.
26 Saenen ND,Vrijens K,Janssen BG,et al.Lower Placental Leptin Promoter Methylation in Association with Fine Particulate Matter Air pollution during pregnancy and placental nitrosative stress at birth in the environ age cohort.Environ Health Perspect,2016,125:262-268.
27 Saenen ND,Vrijens K,Janssen BG,et al.Placental Nitrosative Stress and Exposure to Ambient Air Pollution During Gestation:APopulation Study.Am J Epidemiol,2016,184:442-449.
28 Kannan S,Misra DP,Dvonch JT,et al.Exposures to Airborne Particulate Matter and Adverse Perinatal Outcomes:A Biologically Plausible Mechanistic Framework for Exploring Potential Effect Modification by Nutrition.Environ Health Perspect,2006,114:1636-1642.
29 Lee PC,Talbott EO,Roberts JM,et al.Particulate air pollution exposure and C-reactive protein during early pregnancy.Epidemiology,2011,22:524-531.
30 Sanin LH,López SR,Olivares ET,et al.Relation between birth weight and placenta weight.Biol Neonate,2001,80:113-117.
31 Veras MM,Damaceno-Rodrigues NR,Caldini EG,et al.Particulate urban air pollution affects the functional morphology of mouse placenta.Biol Reprod,2008,79:578-584.
32 Veras MM,Damaceno-Rodrigues NR,Silva RMG,et al.Chronic exposure to fine particulate matter emitted by traffic affects reproductive and fetal outcomes in mice.Environ Res,2009,109:536-543.
33车震.烹调油烟细颗粒物(PM2.5)导致脐带损伤和胎鼠低出生体重.安徽医科大学,2014.
34李莎,王洋,崔国权,等.大气PM2.5污染与孕妇血铅水平的关系.环境与健康杂志,2013,30:338-340.
35赵娜娟.镍污染区大气PM_(2.5)中几种元素对不良妊娠结局的影响及胎盘屏障作用研究.兰州大学,2012.
36董芳燕.镍污染环境暴露对胎儿生长发育的影响及机制研究.兰州大学,2012.
37 Ebisu K,Bell ML.Airborne PM 2.5 Chemical Components and Low Birth Weight in the Northeastern and Mid-Atlantic Regions of the United States.Environ Health Perspect,2012,120:1746-1752.
38 Basu R.Effects of fine particulate matter and its constituents on low birth weight among full-term infants in California.Environ Res,2014,128:42-51.
39赵庆国,李兵,杜玉开.空气污染物对出生体重影响的研究.中国预防医学杂志,2008,9:607-613.
40赵庆国,李兵.户外空气中可吸入颗粒物对出生体重的影响.中国妇幼健康研究,2008,19:4-6.
41 Harris G,Thompson WD,Fitzgerald E,et al.The association of PM2.5 with full term low birth weight at different spatial scales.Environ Res,2014,134:427-434.
42 Lacasa1a M,Esplugues A,Ballester F.Exposure to ambient air pollution and prenatal and early childhood health effects.Eur JEpidemiol,2005,20:183-199.
43 Dadvand P,Parker J,Bell ML,et al.Maternal exposure to particulate air pollution and term birth weight:a multi-country evaluation of effect and heterogeneity.Environ Health Perspect,2013,121:267-373.
44 Hyder A,Lee HJ,Ebisu K,et al.PM2.5 exposure and birth outcomes:Use of satellite-and monitor-based data.Epidemiology,2014,25:58-67.
45赵庆国,梁志江,李兵,等.广东某市空气污染对低出生体重的影响分析.中国妇幼健康研究,2010,21:138-142.
46 He K,Yang F,Ma Y,et al.The characteristics of PM2.5 in Beijing,China.Atmos Environ,2001,35:4959-4970.
47杨复沫,贺克斌,马永亮,等.北京PM2.5浓度的变化特征及其与PM10、TSP的关系.中国环境科学,2002,22:506-510.
48 Duan FK.Concentration and chemical characteristics of PM2.5 in Beijing,China:2001-2002.Sci Total,2006,355:264-275.
2 Wardlaw T,Blanc A,Zupan J,et al.Low birth weight:country regional and global estimates.New York:UNICEF,2004.
3卫生部.中国妇女发展纲要(2011-2020年).
4卫生部.中国儿童发展纲要(2011-2020年).
5 Starzec K,Klimek M,GrudzieńA,et al.Longitudinal assessment of renal size and function in extremely low birth weight children at 7and 11 years of age.Pediatr Nephrol,2016,31:2119-2126.
6 Barker DJ.The fetal origins of coronary heart disease.Eur Heart J,1997,18:883-884.
7 Barker DJ.The fetal and infant origins of adult disease.BMJ,1990,301:1111.
8 Barker D,Eriksson JG,Forsén T,et al.Fetal origins of adult disease:strength of effects and biological basis.Int J Epidemiol,2002,31:1235-1239.
9邵肖梅.成人疾病胎儿起源相关问题---追赶生长的利与弊.中华围产医学杂志,2012,15:129-131.
10 Kelishadi R,Haghdoost AA,Jamshidi F,et al.Low birthweight or rapid catch-up growth:which is more associated with cardiovascular disease and its risk factors in later life?A systematic review and cryptanalysis.Paediatr Int Child Health,2015,35:110-123.
11 Alves JG,Vasconcelos SA,de Almeida TS,et al.Influence of catchup growth on abdominal fat distribution in very low birth weight children-cohort study.J Pediatr Endocr Met,2015,28:153-156.
12 Liu S,Krewski D,Shi Y,et al.Association between maternal exposure to ambient air pollutants during pregnancy and fetal growth restriction.J Expo Sci Environ Epidemiol,2007,17:426-432.
13 Ritz B,Yu F,Fruin S,et al.Ambient Air Pollution and Risk of Birth Defects in Southern California.Am J Epidemiol,2002,155:17-25.
14 Bobak M.Outdoor air pollution,low birth weight,and prematurity.Environ Health Perspect,2000,108:173-176.
15 van den Hooven EH,Pierik FH,de Kluizenaar Y,et al.Air pollution exposure and markers of placental growth and function:the generation R Study.Environ Health Perspect,2012,120:1753-1759.
16 Li X,Huang S,Jiao A,et al.Association between ambient fine particulate matter and preterm birth or term low birth weight:An updated systematic review and meta-analysis.Environ Pollut,2017,227:596-605.
17 Geer L A,Weedon J,Bell M L.Ambient air pollution and term birth weight in Texas from 1998 to 2004.J Air Waste Manage,2012,62:1285-1295.
18 Fleischer NL.Outdoor air pollution,preterm birth,and low birth weight:analysis of the world health organization global survey on maternal and perinatal health.Environ Health Perspect,2014,122:425-430.
19张燕萍,刘旭辉,任展宏,等.太原市大气污染对妊娠结局的影响.环境与健康杂志,2007,24:128-131.
20 Zhao Y,Chen X,Liu X,et al.Exposure of mice to benzo(a)pyrene impairs endometrial receptivity and reduces the number of implantation sites during early pregnancy.Food Chem Toxicol,2014,69:244-251.
21 Talbot P,Lin S.The effect of cigarette smoke on fertilization and preimplantation development:assessment using animal models,clinical data,and stem cells.Biol Res,2011,44:189-194.
22 Ritz B,Yu F,Chapa G,et al.Effect of air pollution on preterm birth among children born in southern California between 1989 and 1993.Epidemiology,2000,11:502-511.
23 Medeiros A.Relationship between low birthweight and air pollution in the city of Sao Paulo,Brazil.Revista De Saude Publica,2005,39:965-972.
24 Dugandzic R,Dodds L,Stieb D,et al.The association between low level exposures to ambient air pollution and term low birth weight:a retrospective cohort study.Evniron Health,2006,5:3-10.
25王双青,王艳梅,董淑英,等.孕期PM2.5暴露与新生儿生长发育关系的初步研究.环境与健康杂志,2014,31:163-166.
26 Saenen ND,Vrijens K,Janssen BG,et al.Lower Placental Leptin Promoter Methylation in Association with Fine Particulate Matter Air pollution during pregnancy and placental nitrosative stress at birth in the environ age cohort.Environ Health Perspect,2016,125:262-268.
27 Saenen ND,Vrijens K,Janssen BG,et al.Placental Nitrosative Stress and Exposure to Ambient Air Pollution During Gestation:APopulation Study.Am J Epidemiol,2016,184:442-449.
28 Kannan S,Misra DP,Dvonch JT,et al.Exposures to Airborne Particulate Matter and Adverse Perinatal Outcomes:A Biologically Plausible Mechanistic Framework for Exploring Potential Effect Modification by Nutrition.Environ Health Perspect,2006,114:1636-1642.
29 Lee PC,Talbott EO,Roberts JM,et al.Particulate air pollution exposure and C-reactive protein during early pregnancy.Epidemiology,2011,22:524-531.
30 Sanin LH,López SR,Olivares ET,et al.Relation between birth weight and placenta weight.Biol Neonate,2001,80:113-117.
31 Veras MM,Damaceno-Rodrigues NR,Caldini EG,et al.Particulate urban air pollution affects the functional morphology of mouse placenta.Biol Reprod,2008,79:578-584.
32 Veras MM,Damaceno-Rodrigues NR,Silva RMG,et al.Chronic exposure to fine particulate matter emitted by traffic affects reproductive and fetal outcomes in mice.Environ Res,2009,109:536-543.
33车震.烹调油烟细颗粒物(PM2.5)导致脐带损伤和胎鼠低出生体重.安徽医科大学,2014.
34李莎,王洋,崔国权,等.大气PM2.5污染与孕妇血铅水平的关系.环境与健康杂志,2013,30:338-340.
35赵娜娟.镍污染区大气PM_(2.5)中几种元素对不良妊娠结局的影响及胎盘屏障作用研究.兰州大学,2012.
36董芳燕.镍污染环境暴露对胎儿生长发育的影响及机制研究.兰州大学,2012.
37 Ebisu K,Bell ML.Airborne PM 2.5 Chemical Components and Low Birth Weight in the Northeastern and Mid-Atlantic Regions of the United States.Environ Health Perspect,2012,120:1746-1752.
38 Basu R.Effects of fine particulate matter and its constituents on low birth weight among full-term infants in California.Environ Res,2014,128:42-51.
39赵庆国,李兵,杜玉开.空气污染物对出生体重影响的研究.中国预防医学杂志,2008,9:607-613.
40赵庆国,李兵.户外空气中可吸入颗粒物对出生体重的影响.中国妇幼健康研究,2008,19:4-6.
41 Harris G,Thompson WD,Fitzgerald E,et al.The association of PM2.5 with full term low birth weight at different spatial scales.Environ Res,2014,134:427-434.
42 Lacasa1a M,Esplugues A,Ballester F.Exposure to ambient air pollution and prenatal and early childhood health effects.Eur JEpidemiol,2005,20:183-199.
43 Dadvand P,Parker J,Bell ML,et al.Maternal exposure to particulate air pollution and term birth weight:a multi-country evaluation of effect and heterogeneity.Environ Health Perspect,2013,121:267-373.
44 Hyder A,Lee HJ,Ebisu K,et al.PM2.5 exposure and birth outcomes:Use of satellite-and monitor-based data.Epidemiology,2014,25:58-67.
45赵庆国,梁志江,李兵,等.广东某市空气污染对低出生体重的影响分析.中国妇幼健康研究,2010,21:138-142.
46 He K,Yang F,Ma Y,et al.The characteristics of PM2.5 in Beijing,China.Atmos Environ,2001,35:4959-4970.
47杨复沫,贺克斌,马永亮,等.北京PM2.5浓度的变化特征及其与PM10、TSP的关系.中国环境科学,2002,22:506-510.
48 Duan FK.Concentration and chemical characteristics of PM2.5 in Beijing,China:2001-2002.Sci Total,2006,355:264-275.