腹腔镜术后GnRH-a治疗对EMT合并不孕患者妊娠结局的影响
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摘要
目的探讨腹腔镜术后GnRH-a治疗对EMT合并不孕患者妊娠结局的影响。方法选取50例拟行腹腔镜手术治疗的EMT伴不孕的患者,随机等分为观察组与对照组,对照组仅予以腹腔镜术治疗,观察组在腹腔镜术后予以GnRH-a治疗,对比两组治疗效果。结果观察组良好结局发生率高于对照组,不良结局发生率低于对照组(P<0.05);观察组治疗后的婚姻质量评分高于对照组(P<0.05)。结论腹腔镜术后GnRH-a治疗能够改善EMT合并不孕患者的妊娠结局,提高其婚姻质量,值得推广。
Objective To investigate the effect of GnRH-a after laparoscopic surgery on the pregnancy outcome of EMT patients with infertility.Methods 50 cases of EMT with infertility treated by laparoscopy were randomly divided into the observation group and the control group. The control group was treated with laparoscopy only.The observation group was treated with GnRH-a after the laparoscopy,and the treatment effect was compared between the two groups.Results The pregnancy rate and natural delivery rate in the observation group were more than those of the control group. The abortion rate, the rate of ectopic pregnancy, the rate of premature delivery and the cesarean section rate were less than those of the control group(P<0.05),and the score of marital quality in the observation group was higher than that of the control group(P<0.05).Conclusion GnRH-a treatment after laparoscopic surgery can improve the pregnancy outcome of EMT patients with infertility and improve their marital quality,which is worthy of promotion.
Objective To investigate the effect of GnRH-a after laparoscopic surgery on the pregnancy outcome of EMT patients with infertility.Methods 50 cases of EMT with infertility treated by laparoscopy were randomly divided into the observation group and the control group. The control group was treated with laparoscopy only.The observation group was treated with GnRH-a after the laparoscopy,and the treatment effect was compared between the two groups.Results The pregnancy rate and natural delivery rate in the observation group were more than those of the control group. The abortion rate, the rate of ectopic pregnancy, the rate of premature delivery and the cesarean section rate were less than those of the control group(P<0.05),and the score of marital quality in the observation group was higher than that of the control group(P<0.05).Conclusion GnRH-a treatment after laparoscopic surgery can improve the pregnancy outcome of EMT patients with infertility and improve their marital quality,which is worthy of promotion.
引文
[1]苏胜红.子宫内膜异位症合并不孕患者腹腔镜术后联合药物治疗对妊娠结局的影响[J].中国计划生育和妇产科,2018,10(01):32-36.
[2]谭振宇.子宫内膜异位症合并不孕患者腹腔镜术后联合药物治疗对妊娠结局的影响[J].医疗装备,2017,30(20):77-78.
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[4]刘洪雪,李健,罗平.宫-腹腔镜联合治疗子宫内膜异位症合并不孕患者术后妊娠的影响因素分析[J].实用妇产科杂志,2017,33(02):144-147.
[5]孙文珍.腹腔镜治疗子宫内膜异位症合并不孕患者术后药物治疗对妊娠结局的影响[J].中外医学研究,2016,14(26):29-30.
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[8] Banghyun lee,hongling du,hugh s taylor Experimental murine endometriosis induces dna methylation and altered gene expression in eutopic endometrium[J].Yale university school of medicine.2009,80(1):79-85.
[2]谭振宇.子宫内膜异位症合并不孕患者腹腔镜术后联合药物治疗对妊娠结局的影响[J].医疗装备,2017,30(20):77-78.
[3]廖美光,单静.腹腔镜联合药物治疗子宫内膜异位症合并不孕症的临床观察[J].海峡药学,2017,29(05):86-87.
[4]刘洪雪,李健,罗平.宫-腹腔镜联合治疗子宫内膜异位症合并不孕患者术后妊娠的影响因素分析[J].实用妇产科杂志,2017,33(02):144-147.
[5]孙文珍.腹腔镜治疗子宫内膜异位症合并不孕患者术后药物治疗对妊娠结局的影响[J].中外医学研究,2016,14(26):29-30.
[6] Fassbender,verbeeck,bornigen.combined mrna microarray and proteomic analysis of eutopic endometrium of women with and without endometriosis[J].human reproduction.2013,28(5):1153-1154.
[7] Kodithuwakku,s.p.pang,r.t.k.ng,wnt activation downregulates olfactomedin-1 in fallopian tubal epithelial cells:a microenvironment predisposed to tubal ectopic pregnancy[J].Laboratory investigation, 2012, 92(2)267-268.
[8] Banghyun lee,hongling du,hugh s taylor Experimental murine endometriosis induces dna methylation and altered gene expression in eutopic endometrium[J].Yale university school of medicine.2009,80(1):79-85.