植物锰转运蛋白研究进展
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摘要
锰是植物必需的微量元素,参与植物的多种生命活动过程,包括光合作用、呼吸作用、蛋白质合成和激素活化等。锰缺乏和过量均能影响植物生长和产量。但是目前对锰在植物中吸收、转运过程的分子机制仍了解有限,少数金属转运蛋白家族被报道参与锰在植物体中的吸收、转运和分配,如NRAMP (natural resistance associated macrophage protein), YSL (yellow stripe-like),ZIP (zinc regulated transporter/iron-regulated transporter [ZRT/IRT1]-related protein),CDF/MTP (cation diffusion facilitator/metal toleranceprotein),CAX (cation exchanger),CCX (calcium cation exchangers),P-type ATPases和VIT (vacuolar iron transporter)。本文主要综述模式植物拟南芥和水稻中锰转运蛋白对锰吸收、分配和维持植物体内锰平衡方面的研究进展,并对相关研究进行展望。
Mn is an essential nutrient which is needed for a variety of life processes in plants, including photosynthesis,respiration, protein synthesis and hormone activation. Mn deficiency or Mn toxicity could affect plant growth and yield.However, relatively little is known about manganese uptake and mobilization in plants. Several transporter protein families have been implicated in Mn uptake and mobilization in plants. These transporter families include NRAMP(natural resistance associated macrophage protein), YSL(yellow stripe-like), ZIP(zinc regulated transporter/iron-regulated transporter [ZRT/IRT1]-related protein), CDF/MTP(cation diffusion facilitator/metal toleranceprotein), CAX(cation exchanger), CCX(calcium cation exchangers), P-type ATPases and VIT(vacuolar iron transporter). This mini review summarized the recent progresses in researchers on these proteins and their roles in the uptake, mobilization,homeostasis of Mn in plants, particularly in the model plants of Arabidopsis thaliana and rice. Prospects on the researches were also discussed.
Mn is an essential nutrient which is needed for a variety of life processes in plants, including photosynthesis,respiration, protein synthesis and hormone activation. Mn deficiency or Mn toxicity could affect plant growth and yield.However, relatively little is known about manganese uptake and mobilization in plants. Several transporter protein families have been implicated in Mn uptake and mobilization in plants. These transporter families include NRAMP(natural resistance associated macrophage protein), YSL(yellow stripe-like), ZIP(zinc regulated transporter/iron-regulated transporter [ZRT/IRT1]-related protein), CDF/MTP(cation diffusion facilitator/metal toleranceprotein), CAX(cation exchanger), CCX(calcium cation exchangers), P-type ATPases and VIT(vacuolar iron transporter). This mini review summarized the recent progresses in researchers on these proteins and their roles in the uptake, mobilization,homeostasis of Mn in plants, particularly in the model plants of Arabidopsis thaliana and rice. Prospects on the researches were also discussed.
引文
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[3]Cailliatte R,Schikora A,Briat J F,et al.High-affinity manganese uptake by the metal transporter NRAMP1 is essential for Arabidopsis growth in low manganese conditions[J].The Plant Cell,2010,22(3):904-917.
[4]Hebbern C A,Pedas P,Schjoerring J K,et al.Genotypic differences in manganese efficiency:field experiments with winter barley(Hordeum vulgare L.)[J].Plant and Soil,2005,272(1/2):233-244.
[5]Hebbern C A,Laursen K H,Ladegaard A H,et al.Latent manganese deficiency increases transpiration in barley(Hordeum vulgare)[J].Physiologia Plantarum,2010,135(3):307-316.
[6]Husted S,Laursen K H,Hebbern C A,et al.Manganese deficiency leads to genotype-specific changes in fluorescence induction kinetics and state transitions[J].Plant Physiology,2009,150(2):825-833.
[7]Marschner H.Marschner’s mineral nutrition of higher plants[M].Pittsburgh:Academic Press,2012.
[8]Kochian L V,Hoekenga O A,Pi?eros M A.How do crop plants tolerate acid soils?Mechanisms of aluminum tolerance and phosphorous efficiency[J].Annual Review of Plant Biology,2004,55(1):459-493.
[9]Bereczky Z,Wang H Y,Schubert V,et al.Differential regulation of nramp and irt metal transporter genes in wild type and iron uptake mutants of tomato[J].Journal of Biological Chemistry,2003,278(27):24697-24704.
[10]Kaiser B N,Moreau S,Castelli J,et al.The soybean NRAMP homologue,Gm DMT1,is a symbiotic divalent metal transporter capable of ferrous iron transport[J].Plant Journal,2010,35(3):295-304.
[11]Xiao H,Yin L,Xu X,et al.The iron-regulated transporter,Mb NRAMP1,isolated from Malus baccata is involved in Fe,Mn and Cd trafficking[J].Annals of Botany,2008,102(6):881-889.
[12]Oomen R J,Wu J,Lelièvre F,et al.Functional characterization of NRAMP3 and NRAMP4 from the metal hyperaccumulator Thlaspi caerulescens[J].New Phytologist,2010,181(3):637-650.
[13]Cailliatte R,Lapeyre B,Briat J F,et al.The NRAMP6 metal transporter contributes to cadmium toxicity[J].Biochemical Journal,2009,422(2):217-228.
[14]Thomine S,Lelièvre F,Debarbieux E,et al.AtNRAMP3,a multispecific vacuolar metal transporter involved in plant responses to iron deficiency[J].The Plant Journal,2003,34(5):685-695.
[15]Lanquar V,Ramos M S,Lelièvre F,et al.Export of vacuolar manganese by AtNRAMP3 and AtNRAMP4 Is required for optimal photosynthesis and growth under manganese deficiency[J].Plant Physiology,2010,152(4):1986-1999.
[16]Yamaji N,Sasaki A,Xia J X,et al.A node-based switch for preferential distribution of manganese in rice[J].Nature Communications,2013,4(9):2442.
[17]Yang M,Zhang W,Dong H,et al.OsNRAMP3 is a vascular bundles-specific manganese transporter that is responsible for manganese distribution in rice[J].PLoS One,2013,8(12):e83990.
[18]Ishimaru Y,Takahashi R,Bashir K,et al.Characterizing the role of rice NRAMP5 in manganese,iron and cadmium transport[J].Scientific Reports,2012,2:286.
[19]Ishimaru Y,Bashir K,Nakanishi H,et al.OsNRAMP5,a major player for constitutive iron and manganese uptake in rice[J].Plant Signaling and Behavior,2012,7(7):763-766.
[20]Yang M,Zhang Y,Zhang L,et al.OsNRAMP5 contributes to manganese translocation and distribution in rice shoots[J].Journal of Experimental Botany,2014,65(17):4849-4861.
[21]杨猛.水稻NRAMP家族基因在Mn和Cd转运中的功能研究[D].武汉:华中农业大学,2014.
[22]Curie C,Panaviene Z,Loulergue C,et al.Maize yellow stripe1 encodes a membrane protein directly involved in Fe(III)uptake[J].Nature,2001,409(6818):346-349.
[23]Jr D D R,Roberts L A,Sanderson T,et al.Arabidopsis Yellow Stripe-Like2(YSL2):a metal-regulated gene encoding a plasma membrane transporter of nicotianamine-metal complexes[J].Plant Journal,2010,39(3):403-414.
[24]Waters B M,Chu H H,Didonato R J,et al.Mutations in Arabidopsis yellow stripe-like1 and yellow stripe-like3 reveal their roles in metal ion homeostasis and loading of metal ions in seeds[J].Plant Physiology,2006,141(4):1446-1458.
[25]Chu H H,Chiecko J,Punshon T,et al.Successful reproduction requires the function of Arabidopsis YELLOWSTRIPE-LIKE1 and YELLOW STRIPE-LIKE3 Metal-Nicotianamine transporters in both vegetative and reproductive structures[J].Plant Physiology,2010,154(1):197-210.
[26]Conte S S,Chu H H,Rodriguez D C,et al.Arabidopsis thaliana Yellow Stripe1-Like4 and Yellow Stripe1-Like6localize to internal cellular membranes and are involved in metal ion homeostasis[J].Front Plant Science,2013,4(283):1-16.
[27]Divol F,Couch D,Conéjéro G,et al.The Arabidopsis YELLOW STRIPE LIKE4 and 6 transporters control iron release from the chloroplast[J].Plant Cell,2013,25(3):1040-1055.
[28]Koike S,Inoue H,Mizuno D,et al.OsYSL2 is a rice metal-nicotianamine transporter that is regulated by iron and expressed in the phloem[J].The Plant Journal,2004,39(3):415-424.
[29]Ishimaru Y,Masuda H,Bashir K,et al.Rice metal-nicotianamine transporter,OsYSL2,is required for the long-distance transport of iron and manganese[J].The Plant Journal,2010,62(3):379-390.
[30]Shao J F,Yamaji N,Shen R F,et al.The key to Mn homeostasis in plants:regulation of Mn transporters[J].Trends in Plant Science,2017,22(3):215-224.
[31]Sasaki A,Yamaji N,Xia J,et al.OsYSL6 is involved in the detoxification of excess manganese in rice[J].Plant Physiology,2011,157(4):1832-1840.
[32]Eide D,Broderius M,Fett J,et al.A novel iron-regulated metal transporter from plants identified by functional expression in yeast[J].Proceedings of the National Academy of Sciences,1996,93(11):5624-5628.
[33]Grotz N,Fox T,Connolly E,et al.Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency[J].Proceedings of the National Academy of Sciences,1998,95(12):7220-7224.
[34]Wintz H,Fox T,Wu Y Y,et al.Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis[J].Journal of Biological Chemistry,2003,278(48):47644-47653.
[35]Pedas P,Ytting C K,Fuglsang A T,et al.Manganese efficiency in barley:identification and characterization of the metal ion transporter Hv IRT1[J].Plant Physiology,2008,148(1):455-466.
[36]Milner M J,Seamon J,Craft E,et al.Transport properties of members of the ZIP family in plants and their role in Zn and Mn homeostasis[J].Journal of Experimental Botany,2013,64(1):369-381.
[37]Zhang H,Zhao S,Li D,et al.Genome-wide analysis of the ZRT,IRT-Like protein(ZIP)family and their responses to metal stress in Populus trichocarpa[J].Plant Molecular Biology Reporter,2017,35(5):534-549.
[38]Fu X Z,Zhou X,Xing F,et al.Genome-wide identification,cloning and functional analysis of the zinc/iron-regulated transporter-like protein(ZIP)gene family in trifoliate orange(Poncirus trifoliata L.Raf.)[J].Frontiers in Plant Science,2017,8:588.
[39]Long L,Persson D P,Duan F,et al.The iron-regulated transporter 1 plays an essential role in uptake,translocation and grain-loading of manganese,but not iron,in barley[J].New Phytologist,2018,217(4):1640-1653.
[40]M?ser P,Thomine S,Schroeder J I,et al.Phylogenetic relationships within cation transporter families of Arabidopsis[J].Plant Physiology,2001,126(4):1646-1667.
[41]Vert G,Grotz N,Dedaldechamp F,et al.IRT1,an Arabidopsis transporter essential for iron uptake from the soil and for plant growth[J].The Plant Cell,2002,14(6):1223-1233.
[42]Yang T J,Perry P J,Ciani S,et al.Manganese deficiency alters the patterning and development of root hairs in Arabidopsis[J].Journal of Experimental Botany,2008,59(12):3453-3464.
[43]Ramegowda,Yamunarani,Venkategowda,et al.Expression of a rice Zn transporter,OsZIP1,increases Zn concentration;in tobacco and finger millet transgenic plants[J].Plant Biotechnology Reports,2013,7(3):309-319.
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