摘要
脂肪源基质血管组分(SVF)细胞是一种具有干细胞特性的异质性细胞群,SVF含有的多种细胞类型使其具有强大的免疫调节、血管新生和组织重建等再生潜能。目前将其应用于多种疾病的临床治疗,均显示出良好的安全性和治愈效果。综述目前提取脂肪源SVF的不同方法及其所含细胞群的具体表型,同时也总结了SVF在脂肪移植、糖尿病、克罗恩病和骨关节炎等多种疾病中的临床应用进展。
Adipose-derived stromal vascular fraction(SVF) cells are a heterogeneous cell population with the characteristics of stem cells.Because of their various cell types, they have strong regenerative potentials such as angiogenesis, tissue remodeling and immune regulation.They have been used for clinic treatment of various conditions with good safety and therapeutic effects. This article reviewed the different separation methods of adipose-derived SVF and characterizes the specific phenotypes of the cells contained in it. At the same time, the advances in clinical applications of SVF in fat transplantation, diabetes, Crohn's disease, osteoarthritis and other diseases were summarized.
引文
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