金马排石汤治疗上尿路结石58例
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摘要
目的:观察金马排石汤治疗上尿路结石的临床疗效。方法:将2016年7月至2017年7月本院接诊的116例上尿路结石患者随机分为观察组和对照组,每组各58例。对照组给予排石颗粒治疗,观察组给予金马排石汤治疗。观察两组患者的临床疗效和并发症发生情况,比较两组患者治疗前后实验室指标[白细胞(white blood cell,WBC)、血红蛋白(he-moglobin,HGB)、血小板计数(platelet,PLT)、丙氨酸氨基转移酶(alanine transaminase,ALT)、天冬氨酸氨基转移酶(aspar-tateaminotransferase,AST)、肌酐(serum creatinine,Scr)、血尿素氮(blood urea nitrogen,BUN)]及生存质量评分。结果:对照组有效率为51. 72%,观察组有效率为87. 93%,两组患者临床疗效比较,差异具有统计学意义(P <0. 05)。两组患者治疗前后WBC、HGB、PLT、ALT、AST、Cr、BUN变化不明显,差异无统计学意义(P> 0. 05)。两组患者治疗后生存质量评分高于治疗前,且观察组高于对照组,差异具有统计学意义(P <0. 05)。观察组并发症发生率与对照组比较,差异无统计学意义(P> 0. 05)。结论:金马排石汤治疗上尿路结石可显著改善患者的生存质量,且对生化指标影响小,并发症较少。
Objective: To observe the clinical curative effect of Jinma Paishi Decoction( JMPSD) on upper urinary calculi. Methods: One hundred and sixteen patients with upper urinary tract calculi treated in our hospital from July 2016 to July 2017 were randomly divided into the observation group and the control group,with 58 cases in each group. The ones in the control group were treated with Paishi Granules( PSG),while the ones in the observation group were treated with JMPSD. Then the clinical efficacies and complications of the two groups were observed. The laboratory indexes [white blood cell( WBC),hemoglobin( HGB),platelet count( PLT),alanine aminotransferase( ALT),aspartate aminotransferase( AST),creatinine( serum creatinine),( serum creatinine,Scr),blood urea nitrogen,BUN) ],and quality of life scores before and after the treatment were compared between the two groups. Results: The effective rate was 51. 72% in the control group and 87. 93% in the observation group. There was a significant difference between the two groups( P < 0. 05). There were no significant differences in WBC,HGB,PLT,ALT,AST,Cr and BUN between the two groups before and after the treatment( P > 0. 05). The quality of life score of the two groups after the treatment was higher than that before the treatment,and the observation group was higher than the control group,the difference was statistically significant( P < 0. 05). There was no significant difference in the incidence of complications between the observation group and the control group( P > 0. 05). Conclusion: JMPSD has a remarkable clinical curative effect on upper urinary calculi,can significantly improve the quality of life of patients,and has little impact on biochemical indicators and fewer complications.
Objective: To observe the clinical curative effect of Jinma Paishi Decoction( JMPSD) on upper urinary calculi. Methods: One hundred and sixteen patients with upper urinary tract calculi treated in our hospital from July 2016 to July 2017 were randomly divided into the observation group and the control group,with 58 cases in each group. The ones in the control group were treated with Paishi Granules( PSG),while the ones in the observation group were treated with JMPSD. Then the clinical efficacies and complications of the two groups were observed. The laboratory indexes [white blood cell( WBC),hemoglobin( HGB),platelet count( PLT),alanine aminotransferase( ALT),aspartate aminotransferase( AST),creatinine( serum creatinine),( serum creatinine,Scr),blood urea nitrogen,BUN) ],and quality of life scores before and after the treatment were compared between the two groups. Results: The effective rate was 51. 72% in the control group and 87. 93% in the observation group. There was a significant difference between the two groups( P < 0. 05). There were no significant differences in WBC,HGB,PLT,ALT,AST,Cr and BUN between the two groups before and after the treatment( P > 0. 05). The quality of life score of the two groups after the treatment was higher than that before the treatment,and the observation group was higher than the control group,the difference was statistically significant( P < 0. 05). There was no significant difference in the incidence of complications between the observation group and the control group( P > 0. 05). Conclusion: JMPSD has a remarkable clinical curative effect on upper urinary calculi,can significantly improve the quality of life of patients,and has little impact on biochemical indicators and fewer complications.
引文
[1]王轩久,王艳玲,柳伟,等.涿州市尿路结石的流行病学现状及危险因素分析[J].天津医药,2014,42(1):71-73.
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[7]赵敏.中医辨证分型治疗上尿路结石85例临床观察[J].新中医,2013,45(3):54-55.
[8]曾永威,高婉仪,邓学斌,等.三水地区成人上尿路结石患者结石成分、中医证型、体质特点及防治策略探讨[J].浙江中医药大学学报,2014,38(11):1290-1295.
[9]朱文静,杨明,彭煜,等.泌尿系结石中西医结合防治模式探讨[J].中医杂志,2015,56(17):1462-1464.
[10]陶荣菊.中医辨证选方与排石通淋专药合用治疗尿路结石[J].光明中医,2012,27(5):1001-1002.
[11]杜围,李显文,徐华,等.输尿管内双J管置入术结合中药排石颗粒治疗尿路结石的临床分析[J].中国医药导报,2011,8(20):37-38.
[12]黄小平,陈协辉,赵立琳,等.上尿路排石冲剂治疗尿路结石的临床研究[J].世界中西医结合杂志,2010,5(2):139-141.
[13]刘江.金马排石汤治疗上尿路结石临床疗效观察[J].临床合理用药杂志,2017,10(4):32-33.
[14]雷家辉,王军,王晓蓉,等.益气补肾排石汤结合体外碎石治疗上尿路结石79例[J].山西中医,2012,28(9):12-13.
[15]马玉生,王永传,许孝新,等.中西医结合方式治疗肾结石前后肾损伤生化指标的变化及其意义研究[J].世界中西医结合杂志,2016,11(5):699-702.
[2]戴红峰,袁顺辉,李泽惠.上尿路结石治疗新进展[J].医学综述,2013,19(17):3166-3169.
[3]严娟,郭小军.基于多元概化理论与结构方程模型对SCL-90量表的信效度分析[J].湖州师范学院学报,2014,36(4):72-76.
[4] NARAYAN V M,BOZORGMEHRI S,ELLEN J H,et al. Evalua-ting Region of Interest Measurement Strategies to Characterize Up-per Urinary Tract Stones on Computerized Tomography[J]. J Urol,2017,197(3):715-722.
[5]江耀明,杨嗣星.上尿路结石的治疗进展[J].医学综述,2012,18(24):4200-4203.
[6]甘星,许远兵.泌尿系结石并发急性感染的危险因素及病原学分析[J].浙江医学,2017,39(6):469-470,472.
[7]赵敏.中医辨证分型治疗上尿路结石85例临床观察[J].新中医,2013,45(3):54-55.
[8]曾永威,高婉仪,邓学斌,等.三水地区成人上尿路结石患者结石成分、中医证型、体质特点及防治策略探讨[J].浙江中医药大学学报,2014,38(11):1290-1295.
[9]朱文静,杨明,彭煜,等.泌尿系结石中西医结合防治模式探讨[J].中医杂志,2015,56(17):1462-1464.
[10]陶荣菊.中医辨证选方与排石通淋专药合用治疗尿路结石[J].光明中医,2012,27(5):1001-1002.
[11]杜围,李显文,徐华,等.输尿管内双J管置入术结合中药排石颗粒治疗尿路结石的临床分析[J].中国医药导报,2011,8(20):37-38.
[12]黄小平,陈协辉,赵立琳,等.上尿路排石冲剂治疗尿路结石的临床研究[J].世界中西医结合杂志,2010,5(2):139-141.
[13]刘江.金马排石汤治疗上尿路结石临床疗效观察[J].临床合理用药杂志,2017,10(4):32-33.
[14]雷家辉,王军,王晓蓉,等.益气补肾排石汤结合体外碎石治疗上尿路结石79例[J].山西中医,2012,28(9):12-13.
[15]马玉生,王永传,许孝新,等.中西医结合方式治疗肾结石前后肾损伤生化指标的变化及其意义研究[J].世界中西医结合杂志,2016,11(5):699-702.