伴髓样特征乳腺癌的超声表现及其病理基础
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摘要
目的探讨伴髓样特征乳腺癌的声像图特征及其病理基础。方法回顾性分析18例伴髓样特征乳腺癌患者的超声及病理资料,观察声像图表现并与病理进行对照。结果伴髓样特征乳腺癌具有边界清晰,内部回声低或极低,后方回声无衰减,钙化少见,血供丰富等声像图特征,其所对应的病理基础为:肿瘤呈膨胀生长,纤维性间质少,成分较单一,主要是大量弥漫排列的肿瘤细胞成分等。结论伴髓样特征乳腺癌的声像图表现有一定特征性,超声检查有助于伴髓样特征乳腺癌与乳腺良性肿瘤及其他类型乳腺癌的鉴别。
Objective To investigate the ultrasonic manifestations and its pathological basis of breast carcinoma with medullary features. Methods The ultrasonic manifestations and its pathological features of 18 patients with breast carcinoma with medullary features were analyzed retrospectively. Results Ultrasonographic sonographic appearance of breast carcinoma with medullary features were as follows: sharply demarcated and low or extremely low of internal echo, no attenuation of posterior echo, rich of blood supply in the tumor. Pathological features of breast carcinoma with medullary features indicated that tumor cells grew fast in a short time and there were a large number of tumor cells and a few of interstitial cells. Conclusion Ultrasonic manifestations of breast carcinoma with medullary features can be helpful in the differentiation diagnosis of the breast carcinoma with medullary features from breast benign tumors and other type of breast carcinomas.
Objective To investigate the ultrasonic manifestations and its pathological basis of breast carcinoma with medullary features. Methods The ultrasonic manifestations and its pathological features of 18 patients with breast carcinoma with medullary features were analyzed retrospectively. Results Ultrasonographic sonographic appearance of breast carcinoma with medullary features were as follows: sharply demarcated and low or extremely low of internal echo, no attenuation of posterior echo, rich of blood supply in the tumor. Pathological features of breast carcinoma with medullary features indicated that tumor cells grew fast in a short time and there were a large number of tumor cells and a few of interstitial cells. Conclusion Ultrasonic manifestations of breast carcinoma with medullary features can be helpful in the differentiation diagnosis of the breast carcinoma with medullary features from breast benign tumors and other type of breast carcinomas.
引文
[1] Sunil R, Lakhani, Lan O, et al. WHO classification of tumours of the breast [M]. Lyon: IARC Press, 2012.368.
[2] 穆坤,吴梓政,牛海飞,等. 乳腺髓样癌临床病理特征及预后分析[J].中华普通外科杂志,2017,32(3):211-214.
[3] 中国医师协会超声医师分会. 血管和浅表器官超声检查指南[M]. 北京:人民军医出版社,2016.113-117.
[4] Adler DD, Carson PL, Rubin JM, et al. Doppler ultrasound color flow imaging in the study of breast cancer: preliminary findings [J]. Ultrasound Med Biol, 1990, 16(6): 553-559.
[5] 阚秀. 随议“乳腺髓样癌”[J]. 诊断病理学杂志,2013,20(9):525, 544.
[6] Nielsen DL, Andersson M, Andersen JL. Antiangiogenic therapy for breast cancer [J]. Breast Cancer Res, 2010, 12(5): 209-215.
[7] Oh SJ, Kim O, Lee JS, et al. Inhibition of angiogenesis by quercetin in tamoxifen-resitant breast cancer cells[J]. Food Chem Toxicol, 2010, 48(11): 3227-3234.
[8] 张缙熙,姜玉新.浅表器官及组织超声诊断[M]. 北京:科技技术文献出版社,2006. 98.
[9] 富丽娜,王怡,黄咏红,等. 乳腺实质性导管内乳头状瘤的超声特征[J].中国医学影像技术,2010,26:1481-1483.
[2] 穆坤,吴梓政,牛海飞,等. 乳腺髓样癌临床病理特征及预后分析[J].中华普通外科杂志,2017,32(3):211-214.
[3] 中国医师协会超声医师分会. 血管和浅表器官超声检查指南[M]. 北京:人民军医出版社,2016.113-117.
[4] Adler DD, Carson PL, Rubin JM, et al. Doppler ultrasound color flow imaging in the study of breast cancer: preliminary findings [J]. Ultrasound Med Biol, 1990, 16(6): 553-559.
[5] 阚秀. 随议“乳腺髓样癌”[J]. 诊断病理学杂志,2013,20(9):525, 544.
[6] Nielsen DL, Andersson M, Andersen JL. Antiangiogenic therapy for breast cancer [J]. Breast Cancer Res, 2010, 12(5): 209-215.
[7] Oh SJ, Kim O, Lee JS, et al. Inhibition of angiogenesis by quercetin in tamoxifen-resitant breast cancer cells[J]. Food Chem Toxicol, 2010, 48(11): 3227-3234.
[8] 张缙熙,姜玉新.浅表器官及组织超声诊断[M]. 北京:科技技术文献出版社,2006. 98.
[9] 富丽娜,王怡,黄咏红,等. 乳腺实质性导管内乳头状瘤的超声特征[J].中国医学影像技术,2010,26:1481-1483.