薄荷的药理作用及临床应用
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摘要
薄荷具有抗病毒、抗菌、抗炎、抗癌、抗氧化、镇痛、解痉等药理作用,临床多用于疏风散热、发汗解表。本文通过对国内外有关文献资料进行归纳总结,并加以概括分析,确定薄荷的药用价值。
Menthae haplocalycis herba has anti-virus, anti-bacterial, anti-inflammatory, anti-cancer, anti-oxidation,analgesic, antispasmodic effects and other pharmacological activities. Its clinical application includes dispelling wind,heat dissipation, sweating and relieving symptoms by sweating. In this paper, the relevant literature at home and abroad were summarized and analyzed to determine the medicinal value of Menthae haplocalycis herba.
Menthae haplocalycis herba has anti-virus, anti-bacterial, anti-inflammatory, anti-cancer, anti-oxidation,analgesic, antispasmodic effects and other pharmacological activities. Its clinical application includes dispelling wind,heat dissipation, sweating and relieving symptoms by sweating. In this paper, the relevant literature at home and abroad were summarized and analyzed to determine the medicinal value of Menthae haplocalycis herba.
引文
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[3]郭晓恒,杨新杰,刘涛,等.药用薄荷的来源研究[J].安徽农业科学, 2013, 41(11):4787-4788.
[4]楚遵雷.薄荷的化学成分和临床药理应用[J].齐鲁药事,2009,28(9):545-546.
[5]曾建伟,钱士辉,吴锦忠.薄荷非挥发性成分研究[J].中国中药杂志, 2006, 31(5):400-402.
[6]任慧娟,任现志.液相色谱质谱联用技术及其在中药现代化研究中的应用究[J].山西中医, 2014, 4(30):54-55.
[7]束雅春,徐丽娟,蔡皓.薄荷化学成分及采收加工研究概况[J].中华中医药学刊, 2013, 31(6):1233-1235.
[8]张继东,王庆琪.薄荷残渣中化学成分及抗炎作用[J].山东医药工业, 2000, 10(3):34-35.
[9]张援虎,刘颖,胡峻,等.薄荷中黄酮类成分的研究[J].中草药,2006, 37(4):512-515.
[10]林彤,段金廒,钱大玮,等.苏薄荷挥发性成分分析及其动态变化研究[J].现代中药研究与实践, 2006, 20(4):28-30.
[11]郑健,赵东升,吴斌,等.留兰香中化学成分的分离与鉴定[J].中国中药杂志, 2002, 27(10):749-751.
[12]梁振益,陈宗宪,刘长生.薄荷中迷迭香酸的分离提取及含量测定[J].天然产物研究与开发, 2005, 17(6):62-64.
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[14]徐凌玉,李振麟,蔡芷辰,等.薄荷化学成分的研究[J].中草药,2013, 44(20):2798-2802.
[15]邱全瑛,关洪权,邹樟.医学免疫学与病原生物学[M].北京:科学出版社, 2007:266-267.
[16]陈祖基.中草药抗单纯疱疹病毒的实验研究[J].中药杂志,1980, 21(3):73-75.
[17]陈飞,姚梅悦,周长征,等.薄荷抗单纯疱疹病毒有效部位筛选研究[J].山东中医杂志, 2015, 34(4):289-291.
[18]Schumacher A,RcichlingJ,SchnitzlerP.Virucidaleffectof peppermint oil on the enveloped viruses herpes simplex virus typle and type 2 in vitro[J]. Phytomedicine, 2003, 10(6-7):504-510.
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[20]Guo W, WangJ,ShengM,etal.Radiologicalfindingsin210pediatricpatientswithviralpneumonia:aretrospectiveease study[J]. Br J Radiol, 2012, 85(1018):1385-1389.
[21]刘华,贺湘玲,张兵,等. 255例急性下呼吸道感染井血小板异常患儿病毒病原学分析[J].中国当代儿科杂志, 2014, 16(4):406-409.
[22]Rodríguez-Auad J P, Nava-Frías M, Casasola-Flores J, et al. The epidemiology and clinical characteristics of respiratory syncytial virus infection in children at a public pediatric referral hospital in Mexieo[J]. Int J Infeet, 2012, 16(7):e508-e513.
[23]李佩佩,杨子君,陈萌,等.薄荷多糖的提取工艺及其抗氧化、抗病毒活性的研究[J].食品科技, 2014, 39(12):196-201.
[24]刘群群.薄荷属植物的化学成分及药理学作用研究[J].现代食品, 2016, 7(19):44-45.
[25]周露,谢文申.云南薄荷精油的化学成分及其抗菌活性研究[J].香料香精化妆品, 2011, 10(5):1-3.
[26]王微,吴楠,祖元刚,等.薄荷精油抗菌活性研究.植物研究,2007, 27(5):626-629.
[27]Haksar A, Sharma A, Chawla R, et al. Mint oil(Mentha spicata Linn.)offerbehavioralradioprotection:radiation-induced conditioned taste aversion study[J]. Phytother Res, 2009, 23:293-296.
[28]SamarthRM,SamarthM.Protectionagainstradiation-induced testicular damage in swiss albio mice by Mentha pipetita(Linn.)[J]. Basic Clin Pharm, 2009, 104:329-334.
[29]SamarthRM,PanwarM,KumarM,etal.Radioprotective influence of Mentha pipetita(Linn.)against gamma irradiation in mice:antioxidant and radical scavenging activity[J]. Int J Radiat Biol, 2006, 82:331-337.
[30]周岩.本草思辨录[M].陆拯,校点.北京:中国中医药出版社,2013:54.
[31]沈映君.中药药理学[M].北京:人民卫生出版社, 2011:129.
[32]刘艳红,钟波. 160例复方薄荷脑俞穴麻醉用于肛肠疾病手术的效果分析[J].中医临床研究, 2014, 6(4):78-79.
[33]马文芳,樊建林,徐海霞,等.薄荷油湿热敷对减轻胸腰椎压缩性骨折患者腹胀的疗效观察[J].实用临床医药杂志, 2015,19(14):153-157.
[34]程阔菊,王晖,陈垦.薄荷醇的安全性研究进展[J].辽宁中医杂志, 2011, 37(2):377-379.
[35]高月平,张瑾.自拟冰片薄荷汤治疗阴道炎的临床研究[J].辽宁中医杂志, 2010, 37(10):1991-1992.
[36]陈向阳.薄荷酚类部位化学成分及抗炎活性研究[D].北京:北京中医药大学, 2016-06.
[2]沈梅芳,李小萌,单琪媛.薄荷化学成分与药理作用研究新进展[J].中华中医药学刊, 2012, 7:1484-1487.
[3]郭晓恒,杨新杰,刘涛,等.药用薄荷的来源研究[J].安徽农业科学, 2013, 41(11):4787-4788.
[4]楚遵雷.薄荷的化学成分和临床药理应用[J].齐鲁药事,2009,28(9):545-546.
[5]曾建伟,钱士辉,吴锦忠.薄荷非挥发性成分研究[J].中国中药杂志, 2006, 31(5):400-402.
[6]任慧娟,任现志.液相色谱质谱联用技术及其在中药现代化研究中的应用究[J].山西中医, 2014, 4(30):54-55.
[7]束雅春,徐丽娟,蔡皓.薄荷化学成分及采收加工研究概况[J].中华中医药学刊, 2013, 31(6):1233-1235.
[8]张继东,王庆琪.薄荷残渣中化学成分及抗炎作用[J].山东医药工业, 2000, 10(3):34-35.
[9]张援虎,刘颖,胡峻,等.薄荷中黄酮类成分的研究[J].中草药,2006, 37(4):512-515.
[10]林彤,段金廒,钱大玮,等.苏薄荷挥发性成分分析及其动态变化研究[J].现代中药研究与实践, 2006, 20(4):28-30.
[11]郑健,赵东升,吴斌,等.留兰香中化学成分的分离与鉴定[J].中国中药杂志, 2002, 27(10):749-751.
[12]梁振益,陈宗宪,刘长生.薄荷中迷迭香酸的分离提取及含量测定[J].天然产物研究与开发, 2005, 17(6):62-64.
[13]Dorman H J, Ko?ar M, Kahlos K, et al. Antioxidant properties and compositionofaqueousextractsfromMenthaspecies,hybrids,varieties, and cultivars[J]. J Agr Food Chem, 2003, 51(16):4563-4569.
[14]徐凌玉,李振麟,蔡芷辰,等.薄荷化学成分的研究[J].中草药,2013, 44(20):2798-2802.
[15]邱全瑛,关洪权,邹樟.医学免疫学与病原生物学[M].北京:科学出版社, 2007:266-267.
[16]陈祖基.中草药抗单纯疱疹病毒的实验研究[J].中药杂志,1980, 21(3):73-75.
[17]陈飞,姚梅悦,周长征,等.薄荷抗单纯疱疹病毒有效部位筛选研究[J].山东中医杂志, 2015, 34(4):289-291.
[18]Schumacher A,RcichlingJ,SchnitzlerP.Virucidaleffectof peppermint oil on the enveloped viruses herpes simplex virus typle and type 2 in vitro[J]. Phytomedicine, 2003, 10(6-7):504-510.
[19]NairH,NokesDJ,GessnerBD,etal.Globalburdenofaeute lower respiratory infections due to respiratory syneytial virus in young children:a systematic review and meta-analysis[J].Lancet,2010, 375(9725):1545-1555.
[20]Guo W, WangJ,ShengM,etal.Radiologicalfindingsin210pediatricpatientswithviralpneumonia:aretrospectiveease study[J]. Br J Radiol, 2012, 85(1018):1385-1389.
[21]刘华,贺湘玲,张兵,等. 255例急性下呼吸道感染井血小板异常患儿病毒病原学分析[J].中国当代儿科杂志, 2014, 16(4):406-409.
[22]Rodríguez-Auad J P, Nava-Frías M, Casasola-Flores J, et al. The epidemiology and clinical characteristics of respiratory syncytial virus infection in children at a public pediatric referral hospital in Mexieo[J]. Int J Infeet, 2012, 16(7):e508-e513.
[23]李佩佩,杨子君,陈萌,等.薄荷多糖的提取工艺及其抗氧化、抗病毒活性的研究[J].食品科技, 2014, 39(12):196-201.
[24]刘群群.薄荷属植物的化学成分及药理学作用研究[J].现代食品, 2016, 7(19):44-45.
[25]周露,谢文申.云南薄荷精油的化学成分及其抗菌活性研究[J].香料香精化妆品, 2011, 10(5):1-3.
[26]王微,吴楠,祖元刚,等.薄荷精油抗菌活性研究.植物研究,2007, 27(5):626-629.
[27]Haksar A, Sharma A, Chawla R, et al. Mint oil(Mentha spicata Linn.)offerbehavioralradioprotection:radiation-induced conditioned taste aversion study[J]. Phytother Res, 2009, 23:293-296.
[28]SamarthRM,SamarthM.Protectionagainstradiation-induced testicular damage in swiss albio mice by Mentha pipetita(Linn.)[J]. Basic Clin Pharm, 2009, 104:329-334.
[29]SamarthRM,PanwarM,KumarM,etal.Radioprotective influence of Mentha pipetita(Linn.)against gamma irradiation in mice:antioxidant and radical scavenging activity[J]. Int J Radiat Biol, 2006, 82:331-337.
[30]周岩.本草思辨录[M].陆拯,校点.北京:中国中医药出版社,2013:54.
[31]沈映君.中药药理学[M].北京:人民卫生出版社, 2011:129.
[32]刘艳红,钟波. 160例复方薄荷脑俞穴麻醉用于肛肠疾病手术的效果分析[J].中医临床研究, 2014, 6(4):78-79.
[33]马文芳,樊建林,徐海霞,等.薄荷油湿热敷对减轻胸腰椎压缩性骨折患者腹胀的疗效观察[J].实用临床医药杂志, 2015,19(14):153-157.
[34]程阔菊,王晖,陈垦.薄荷醇的安全性研究进展[J].辽宁中医杂志, 2011, 37(2):377-379.
[35]高月平,张瑾.自拟冰片薄荷汤治疗阴道炎的临床研究[J].辽宁中医杂志, 2010, 37(10):1991-1992.
[36]陈向阳.薄荷酚类部位化学成分及抗炎活性研究[D].北京:北京中医药大学, 2016-06.