在无痛人流中应用丙泊酚配伍芬太尼静脉麻醉的效果观察
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摘要
目的探索在无痛人流中应用丙泊酚配伍芬太尼静脉麻醉的效果。方法选取2017年6月22日至2018年6月22日期间本院无痛人流100例患者(实施奇偶数分组模式),对照组的50例患者进行瑞芬太尼麻醉,观察组的50例患者进行丙泊酚配伍芬太尼麻醉,随后对比镇静、镇痛效果以及麻醉安全性和睁眼时间、睫毛反射消失时间、自主呼吸时间、定向力恢复时间。结果观察组清醒后12h Ramsay评分[(2.45±0.62)分]、清醒后48h Ramsay评分[(2.19±0.34)分]、睁眼时间[(7.15±1.28)min]、睫毛反射消失时间[(4.16±1.22)min]、自主呼吸时间[(5.28±0.76)min]、定向力恢复时间[(15.15±1.28)min]、不良反应(4.00%)、清醒时VAS评分[(2.18±0.75)分]、清醒后12h VAS评分[(1.65±1.85)分]、清醒后48h VAS评分[(1.02±0.35)分]均优于对照组(P<0.05)。结论丙泊酚配伍芬太尼用于无痛人流中效果明显。
Objective To explore the effect of propofol combined with fentanyl intravenous anesthesia in painless abortion. Methods 100 patients with painless abortion in our hospital from June 22, 2017 to June 22, 2018 were enrolled(parity grouping mode), 50 patients in the control group underwent remifentanil anesthesia. 50 patients in the observation group were anesthetized with propofol and fentanyl, then contrast sedation, analgesic effect and anesthesia safety and blink time, eyelash reflex disappearance time, spontaneous breathing time, orientation recovery time. Results The observation group showed a 12 h Ramsay score(2.45±0.62), 48 h Ramsay score(2.19±0.34), blink time [(7.15±1.28) min], eyelash reflex disappearance time [(4.16±1.22) min], and autonomy, respiration time [(5.28±0.76) min], orientation recovery time [(15.15±1.28) min], adverse reactions(4.00%), VAS score(2.18±0.75) when awake, VAS score(1.65±1.85) after 12 hours of waking, the VAS score(1.02±0.35) of 48 h after waking were better than those in the control group(P<0.05). Conclusion Propofol combined with fentanyl is effective in painless abortion.
Objective To explore the effect of propofol combined with fentanyl intravenous anesthesia in painless abortion. Methods 100 patients with painless abortion in our hospital from June 22, 2017 to June 22, 2018 were enrolled(parity grouping mode), 50 patients in the control group underwent remifentanil anesthesia. 50 patients in the observation group were anesthetized with propofol and fentanyl, then contrast sedation, analgesic effect and anesthesia safety and blink time, eyelash reflex disappearance time, spontaneous breathing time, orientation recovery time. Results The observation group showed a 12 h Ramsay score(2.45±0.62), 48 h Ramsay score(2.19±0.34), blink time [(7.15±1.28) min], eyelash reflex disappearance time [(4.16±1.22) min], and autonomy, respiration time [(5.28±0.76) min], orientation recovery time [(15.15±1.28) min], adverse reactions(4.00%), VAS score(2.18±0.75) when awake, VAS score(1.65±1.85) after 12 hours of waking, the VAS score(1.02±0.35) of 48 h after waking were better than those in the control group(P<0.05). Conclusion Propofol combined with fentanyl is effective in painless abortion.
引文
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[10]农兰依,王高强,黄晓媚,等.丙泊酚复合芬太尼或舒芬太尼用于门诊无痛人流手术的效果对比分析[J].海峡药学,2018,30(3):95-97.
[11]于建林.联用米索前列醇、芬太尼及丙泊酚进行无痛人流复合麻醉的效果分析[J].当代医药论丛,2014,17(14):296-296.
[12]魏军标.芬太尼、丙泊酚合并小剂量咪唑安定静脉麻醉无痛人流术中的疗效及安全性分析[J].岭南急诊医学杂志,2016,21(2):169-170.
[2]周晓明,喻南慧,李玉飞,等.地佐辛与芬太尼复合丙泊酚用于无痛人工流产麻醉的临床对比分析[J].湖南师范大学学报(医学版),2017,14(4):37-40.
[3]刘蓉.丙泊酚联合芬太尼静脉泵注对于无痛人工流产妇的认知功能影响研究[J].中国医药导刊,2013,15(11):1856-1857.
[4]开红英.无痛人流术中应用依托咪酯复合地佐辛、丙泊酚与丙泊酚复合芬太尼的价值分析[J].实用妇科内分泌电子杂志,2017,4(30):49-50.
[5]杨秀珍,汪颖.探讨米索前列醇不同用法配合枸橼酸芬太尼、丙泊酚进行无痛人流麻醉的方案选择[J].卫生职业教育,2018,36(10):143-144.
[6]于鹏勇,宁伟,曹金军,等.无痛人流术中应用丙泊酚分别复合舒芬太尼和芬太尼的研究[J].内蒙古医学杂志,2016,48(10):1223-1224.
[7]王华.丙泊酚复合小剂量芬太尼在无痛人流麻醉应用中的效果和安全性分析[J].临床合理用药杂志,2018,11(5):63-64.
[8]张信鹏.用丙泊酚联合小剂量的芬太尼对接受无痛人流手术的孕妇进行麻醉的效果[J].当代医药论丛,2018,16(2):56-57.
[9]苏春华,杨高升.丙泊酚联合芬太尼不同给药方式在无痛人流中的应用效果分析[J].临床医学工程,2016,23(4):445-446.
[10]农兰依,王高强,黄晓媚,等.丙泊酚复合芬太尼或舒芬太尼用于门诊无痛人流手术的效果对比分析[J].海峡药学,2018,30(3):95-97.
[11]于建林.联用米索前列醇、芬太尼及丙泊酚进行无痛人流复合麻醉的效果分析[J].当代医药论丛,2014,17(14):296-296.
[12]魏军标.芬太尼、丙泊酚合并小剂量咪唑安定静脉麻醉无痛人流术中的疗效及安全性分析[J].岭南急诊医学杂志,2016,21(2):169-170.