补阳还五汤加减联合早期康复训练对脑梗死恢复期临床疗效和日常生活活动能力影响
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摘要
目的:观察补阳还五汤加减联合早期康复训练对脑梗死恢复期临床疗效和日常生活活动能力影响。方法:将60例患者随机分为两组各30例。治疗组在对照组基础上口服补阳还五汤加减治疗,疗程均4周,观察治疗前后中医证候积分、神经功能缺损、日常生活活动能力改善情况。结果:总有效率治疗组93.33%,优于对照组76.67%,两组临床疗效有显著性差异(P<0.05);治疗组治疗后神经功能缺损评分(NIHSS评分)及Barthel指数评分均优于对照组,两组比较,差异有显著性意义(P<0.05)。结论:补阳还五汤加减联合早期康复训练治疗脑梗死恢复期具有较好的治疗效果,可明显改善中医证候,还可改善神经功能缺损和提高日常生活活动能力。
Objective: To observe the clinical effect and daily living ability of Buyang Huanwu decoction(补阳还五汤) with early rehabilitative intervention on cerebral infarction recovery stage. Methods: 60 cases were randomly divided into two groups(with 30 cases in each group). The treatment group was given Buyang Huanwu decoction(补阳还五汤) for 4 weeks on the basis of the treatment of the control group. The integral of TCM symptoms, neurologic impairment, activity capacity in daily life before and after treatment of two groups were observed. Results: The total effective rate of the treatment group was 93.33%, which was superior to that of the control group, 76.67%, there was a significant difference in clinical efficacy between the two groups(P<0.05). NIHSS score and Barthel index scores after treatment in the treatment group were superior to those of the control group. There was significant difference between the two groups(P<0.05). Conclusion: Buyang Huanwu decoction(补阳还五汤) combined with early rehabilitative intervention had better therapeutic effect on cerebral infarction recovery stage, it could significantly relieve the symptoms of TCM, enhance the nerve function defect and improve the ability of daily life.
Objective: To observe the clinical effect and daily living ability of Buyang Huanwu decoction(补阳还五汤) with early rehabilitative intervention on cerebral infarction recovery stage. Methods: 60 cases were randomly divided into two groups(with 30 cases in each group). The treatment group was given Buyang Huanwu decoction(补阳还五汤) for 4 weeks on the basis of the treatment of the control group. The integral of TCM symptoms, neurologic impairment, activity capacity in daily life before and after treatment of two groups were observed. Results: The total effective rate of the treatment group was 93.33%, which was superior to that of the control group, 76.67%, there was a significant difference in clinical efficacy between the two groups(P<0.05). NIHSS score and Barthel index scores after treatment in the treatment group were superior to those of the control group. There was significant difference between the two groups(P<0.05). Conclusion: Buyang Huanwu decoction(补阳还五汤) combined with early rehabilitative intervention had better therapeutic effect on cerebral infarction recovery stage, it could significantly relieve the symptoms of TCM, enhance the nerve function defect and improve the ability of daily life.
引文
[1]苏浩,赵苡,黄昭,等.针灸配合补阳还五汤治疗脑梗死后遗症68例临床观察[J].现代生物医学进展,2013,13(32):6347-6350.
[2]中华医学会神经病学分会,脑血管病学组急性缺血性脑卒中诊断指南撰写组.中国急性缺血性脑卒中诊断指南2010[J].中华神经科杂志,2010,43(2):1-7.
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[6]曾平,符秀琼,王启瑞,等.加味补阳还五汤对动脉粥样硬化斑块形成及炎症细胞因子表达谱的影响[J].中药药理与临床,2009,25(6):11-13.
[7]宫健伟,叶蕾.补阳还五汤对脑缺血再灌注大鼠脑组织NO及NOS的影响[J].长春中医药大学学报,2010,26(6):819-820.
[2]中华医学会神经病学分会,脑血管病学组急性缺血性脑卒中诊断指南撰写组.中国急性缺血性脑卒中诊断指南2010[J].中华神经科杂志,2010,43(2):1-7.
[3]郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:99-104.
[4]解庆凡.气虚病机对中风病康复过程的影响[J].中华临床新医学,2004,4(6):541.
[5]李坤买.加味补阳还五汤治疗脑梗死恢复期及后遗症48例[J].中医临床研究,2015(14):101.
[6]曾平,符秀琼,王启瑞,等.加味补阳还五汤对动脉粥样硬化斑块形成及炎症细胞因子表达谱的影响[J].中药药理与临床,2009,25(6):11-13.
[7]宫健伟,叶蕾.补阳还五汤对脑缺血再灌注大鼠脑组织NO及NOS的影响[J].长春中医药大学学报,2010,26(6):819-820.