摘要
骨骼肌损伤为临床常见损伤疾病之一,常给伤者造成较为严重的不良后果。近年来诸多实验及研究已证实生长因子为影响骨骼肌损伤修复的重要因素之一。推拿作为临床骨骼肌损伤最常用且疗效较佳的治疗方法之一,在骨骼肌损伤的治疗中发挥着极其重要的作用,相关实验及研究证明推拿治疗骨骼肌损伤的作用机理与通过干预相关生长因子有关。
Skeletal muscle injury is one of the common clinical injury diseases and often causes serious adverse consequences to the injured. In recent years,many experiments and studies have confirmed that growth factor is one of the important factors affecting the repair of skeletal muscle injury. Massage,as one of the most commonly used and effective treatment methods for clinical skeletal muscle injury,plays an extremely important role in the treatment of skeletal muscle injury. Related experiments and studies have proved that the mechanism of massage in treating skeletal muscle injury is related to the intervention on the related growth factors.
引文
[1]廖远朋.不同运动方式对大鼠骨骼肌急性损伤修复影响的研究[D].北京:北京体育大学,2010.
[2]谢娇,邓多喜,陈英,等.推拿手法对骨骼肌损伤干预研究的进展[J].湖南中医杂志,2018,34(4):199-201.
[3]Hanssen KE,Kvamme NH,Nilsen TS,et al.The effect of strength training volume on satellite cells,myogenic regulatory factors,and growth factors[J].Medicine And Science Sports,2013,23(6):728-739.
[4]刘洪柏,区丽明.富血小板血浆联合转化生长因子-β1抗体对大鼠骨骼肌损伤修复的研究[J].生物医学工程与临床,2018,22(2):188.
[5]刘仁建.按摩对损伤骨骼肌生长因子b FGF、IGF-Ⅰ及致瘢痕因子TGF-β1、COL-Ⅰ的影响研究[D].重庆:重庆医科大学,2013.
[6]谢辉.在骨骼肌损伤修复过程中按摩对自由基相关酶和成肌调节因子的影响研究[D].重庆:重庆医科大学中医药学院,2014.
[7]李江,包海姣,谢平波,等.衰老对骨骼肌卫星细胞增殖分化影响的研究进展[J].山东医药,2018,58(45):95-99.
[8]郑琪,睢梦华,凌英会.骨骼肌卫星细胞增殖与成肌分化过程中关键信号通路的作用[J].畜牧兽医学报,2017,48(11):2005-2006.
[9]熊慧,浦亚斌,马月辉,等.骨骼肌卫星细胞自我更新的分子调节[J].生物医学工程学杂志,2014,31(5):1168.
[10]李方华,弓慧敏,冯士彬,等.骨骼肌卫星细胞的研究进展[J].中国畜牧兽医,2010,37(10):25.
[11]马书杰,严隽陶,黄品贤.推拿手法防治失神经骨骼肌萎缩的实验研究[J].江苏中医药,2014,46(11):79-81.
[12]Miller BF,Hamilton KL,Majeed ZR,et al.Enhanced skeletal muscle regrowth and remodelling in massaged and contralateral non-massaged hindlimb[J].The Journal of physiology,2018,596(1):83-103.
[13]王志强,毛忠清,窦思东,等.手法对颈椎病家兔骨骼肌卫星细胞影响的观察[J].按摩与康复医学,2018,9(12):27-29.
[14]杨辉,常青,唐成林.跑台运动训练与按摩联合作用对大鼠骨骼肌急性损伤修复过程中炎症的发展及肌卫星细胞增殖的影响[J].体育科学,2015,35(3):51-58.
[15]张婷婷.r AAV2介导b FGF基因修饰间充质干细胞对小鼠骨骼肌钝挫伤修复的研究[D].苏州:苏州大学,2016.
[16]谢思圳,唐乾利.碱性成纤维细胞生长因子对创面愈合作用的研究进展[J].右江民族医学院学报,2017,39(4):307.
[17]李林峰,曾达,林伟.大鼠骨骼肌挫伤后b FGF与c-Fos阳性细胞率比值与损伤时间关系的研究[J].成都医学院学报,2018,13(4):407.
[18]何兰,蔺洁,李辉.创伤修复中的EGF和b FGF应用价值[J].临床医药文献杂志,2018,5(15):195.
[19]皮肖冰,谢志红,潘景良.308nm准分子激光对寻常型稳定期白癜风患者皮肤组织液TNF-α、b FGF水平的影响[J].皮肤性病诊疗学杂志,2014,21(2):95-98.
[20]许志锋,李敬来,韩振.碱性成纤维细胞生长因子基因修饰骨骼肌卫星细胞自体移植急性心肌梗死组织的血管新生[J].中国组织工程研究,2017,21(9):1397-1401.
[21]Shi H,Xie H,Zhao Y,et al.Myoprotective effects of b FGF on skeletal muscle injury in pressure-related deep tissue injury in rats[J].Burns Trauma.2016,4(12):26.
[22]Ferreira MM,Dewi RE,Heilshorn SC.Microfluidic analysis of extracellular matrix-b FGF crosstalk on primary human myoblast chemoproliferation,chemokinesis,and chemotaxis[J].Integr Biol(Camb),2015,7(5):569-579.
[23]Ratajczak-Wielgomas K,Kassolik K,Grzegrzolka J,et al.Effects of massage on the expression of proangiogenic markers in rat skin[J].Folia Histochem Cytobiol,2018,1(2):83-91.
[24]陈宏贞.按摩对骨骼肌损伤修复过程中b FGF表达的影响[D].武汉:武汉体育学院,2009.
[25]刘仁建,唐成林,邹敏.兔骨骼肌钝挫伤恢复过程中碱性成纤维细胞生长因子的变化及按摩的干预作用[J].重庆医科大学学报,2013,38(11):1303-1307.
[26]翁军,郭汝宝,李增图,等.推拿手法对家兔失神经支配后骨骼肌IGF-Ⅰ、b FGF、Myo D表达的影响[J].中华中医药杂志,2015,30(10):3716-3719.
[27]李飞虹,尚茹茹,吕淑萍.胰岛素样生长因子1对血管平滑肌细胞凋亡的影响[J].中华临床医师杂志,2017,11(5):759.
[28]刘晓光,徐苗苗,陈佩杰.IGF-1在治疗骨骼肌损伤中的应用潜能及其相关机制[J].生命的化学,2016,36(4):496-502.
[29]刘强,赵相轩,潘诗农.骨骼肌细胞损伤致延迟性肌肉酸痛:如何有效提高损伤肌肉恢复的速度和质量[J].中国组织工程研究,2014,18(38):6189-6193.
[30]刘仁建,唐成林,邹敏,等.按摩对兔骨骼肌顿挫伤修复过程中IGF-Ⅰ的影响[J].激光杂志,2013,34(4):102-104.
[31]向勇,王春林,董有康,等.柔和手法对兔骨骼肌慢性损伤修复过程中生长因子的影响[J].河南中医,2018,38(7):1016-1019.
[32]张婵娟,成羿,董学亮.轻揉推拿法对兔骨骼肌急性钝挫伤组织观察及IGFmRNA表达的影响[J].浙江临床医学,2015,17(10):1668-1670.
[33]刘志华.回医理筋手法对家兔骨骼肌损伤修复过程中IGF-1表达的影响[D].宁夏:宁夏医科大学,2014.
[34]Chiba T,Ishisaki A,Kyakumoto S,et al.Transforming growth factor-β1 suppresses bone morphogenetic protein-2-induced mesenchymalepithelial transition in HSC-4 human oral squamous cell carcinoma cells via Smad1/5/9 pathway suppression[J].Oncol Rep,2017,37(2):713-720.
[35]王康康.细胞因子及细胞打印技术与骨骼肌损伤修复[J].中国组织工程研究,2017,21(20):3241-3247.
[36]赵佳佳.杨丕波,韩传火,等.大鼠皮肤创伤修复过程中转化生长因子β1和β3的表达[J].中国组织工程研究,2013,17(20):3647.
[37]Zhao W,Yan J,Gao L,et al.Cdk5 is required for the neuroprotective effect of transforming growth factor-β1 against cerebral ischemiareperfusion[J].Biochem Biophys Res Commun,2017,485(4):775-781.
[38]Xin Xu,Liwei Zheng,Quan Yuan.Transforming growth factor-βin stem cells and tissue homeostasis[J].Bone Research,2018,6(2):4-17.
[39]于新凯,石鹏超,左群.转化生长因子β与骨骼肌损伤修复的研究进展[J].解剖科学进展,2014,20(2):158-161.
[40]Best TM,Gharaibeh B,Huard J.Stem cells,angiogenesis and muscle healing:a potential role in massage therapies?[J].Postgraduate medical journal,2013,89(1057):666-670.
[41]Zhao W,Yan J,Gao L,et al.Cdk5 is required for the neuroprotective effect of transforming growth factor-β1 against cerebral ischemiareperfusion[J].Biochem Biophys Res Commun,2017,485(4):775-781.
[42]Chiba T,Ishisaki A,Kyakumoto S,et al.Transforming growth factor-β1 suppresses bone morphogenetic protein-2-induced mesenchymalepithelial transition in HSC-4 human oral squamous cell carcinoma cells via Smad1/5/9 pathway suppression[J].Oncol Rep,2017,37(2):713-720.
[43]Delaney K,Kasprzycka P,Ciemerych MA,et al.The role of TGF-β1during skeletal muscle regeneration[J].Cell Biol Int,2017,41(7):706-715.
[44]王一洲,冯伟,赵强.屈膝点按叩揉法影响TGF-β/Smad通路促进损伤肌腱修复的作用机制研究[J].天津中医药大学学报,2017,36(3):205-208.
[45]谢辉.在骨骼肌损伤修复过程中按摩对自由基相关酶和成肌调节因子的影响研究[D].重庆:重庆医科大学中医药学院,2014.
[46]高永红,邱明才.血管内皮细胞生长因子的结构及其多种生物学效应[J].中国组织工程研究与临床康复,2008,12(15):2951-2955.
[47]蔡宇豪,管军.血管内皮生长因子基因多态性与冠心病相关性研究进展[J].中西医结合心血管病杂志,2018,6(7):44.
[48]Baum O,Jentsch L,Odriozola A,et al.Ultrastructure of Skeletal Muscles in Mice Lacking Muscle-Specific VEGF Expression[J].Anat Rec(Hoboken),2017,300(12):2239-2249.
[49]Huey KA.Potential Roles of Vascular Endothelial Growth Factor During Skeletal Muscle Hypertrophy[J].Exerc Sport Sci Rev,2018,46(3):195-202.
[50]Andrzejewski W,Kassolik K,Kobierzycki C1,et al.Increased skeletal muscle expression of VEGF induced by massage and exercise[J].Folia Histochem Cytobiol,2015,53(2):145-151.
[51]谢辉,唐成林,陈晓琳.按摩通过改善VEGF活性及血供促进兔骨骼肌损伤修复[J].中国老年学杂志,2014,34(24):6984-6986.
[52]郜婕,唐成林,邹敏.穴位按摩对受损骨骼肌血管内皮生长因子表达微泡超声造影及血液流变的影响[J].中华物理医学与康复杂志,2013,35(2):91-95.
[53]朱卓立,马瑞阳,杨扬.不同频率微振动对血管内皮细胞生长因子表达及通透性的影响[J].华西口腔医学杂志,2016,34(2):136-139.