二联用药联合睡眠干预对社区高血压患者血压控制率及睡眠质量的影响研究
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摘要
目的:探讨二联用药联合睡眠干预在社区高血压患者临床治疗中的应用价值。方法:选取2017年1月至2018年5月昌平城区社区卫生服务中心收治的高血压患者60例作为研究对象,随机分为对照组和观察组,每组30例,对照组单用非洛地平治疗,观察组应用美托洛尔联合非洛地平治疗二联用药治疗,并对患者的睡眠质量进行干预和监测,观察2组临床疗效和治疗前后患者睡眠质量。结果:治疗2个月后,观察组患者收缩压、舒张压指标水平均较治疗前及观察组治疗后下降;观察组患者治疗期间不良反应发生率显著低于对照组的发生率;观察组患者睡眠质量优于对照组,差异有统计学意义(P <0. 05)。结论:针对社区高血压疾病,联合应用美托洛尔+非洛地平治疗,并同步实施睡眠监测干预可获得良好降压效果,同时改善患者睡眠质量,且可降低药物不良反应,值得推广。
Objective: To explore the clinical application value of two-drug combined with sleep intervention in community hypertension patients. Methods: Will be in January 2017 to May 2018 of 60 patients admitted in the community hypertension patients randomly divided into observation group( 30 cases) and control group( 30 cases) and control group,with felodipine treatment,observation group application of metoprolol combined felodipine duplex treatment drug treatment,and the sleep quality of patients with intervention and monitoring,observing two groups of patients before and after the clinical curative effect and treatment of sleep quality. Results: After 2 months of treatment,the systolic blood pressure and diastolic blood pressure in the observation group were lower than those before and after treatment. The incidence of adverse reactions during treatment was significantly lower in the observation group than in the control group. The quality of sleep in the observation group was better than that in the control group,and the difference was statistically significant( P < 0. 05). Conclusion: For hypertension in the community,combined application of metoprolol + felodipine therapy and synchronous implementation of sleep monitoring intervention can achieve good antihypertensive effect,improve patients' sleep quality at the same time,and reduce adverse drug reactions,which is worthy of promotion.
Objective: To explore the clinical application value of two-drug combined with sleep intervention in community hypertension patients. Methods: Will be in January 2017 to May 2018 of 60 patients admitted in the community hypertension patients randomly divided into observation group( 30 cases) and control group( 30 cases) and control group,with felodipine treatment,observation group application of metoprolol combined felodipine duplex treatment drug treatment,and the sleep quality of patients with intervention and monitoring,observing two groups of patients before and after the clinical curative effect and treatment of sleep quality. Results: After 2 months of treatment,the systolic blood pressure and diastolic blood pressure in the observation group were lower than those before and after treatment. The incidence of adverse reactions during treatment was significantly lower in the observation group than in the control group. The quality of sleep in the observation group was better than that in the control group,and the difference was statistically significant( P < 0. 05). Conclusion: For hypertension in the community,combined application of metoprolol + felodipine therapy and synchronous implementation of sleep monitoring intervention can achieve good antihypertensive effect,improve patients' sleep quality at the same time,and reduce adverse drug reactions,which is worthy of promotion.
引文
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[3]夏卫,黄静静,王瑞东,等.清脑降压片联合非洛地平缓释片治疗原发性高血压的临床研究[J].现代药物与临床,2016,31(5):628-631.
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[7]王否,顾佳怡,徐辉,等.社区综合健康管理对老年高血压患者生命质量的影响[J].中华疾病控制杂志,2018,22(7):708-711,716.
[8]阎善林.硝苯地平辅助治疗老年高血压的临床疗效及对睡眠质量的影响[J].世界睡眠医学杂志,2018,5(6):652-655.
[9]陈青青,陈美佳,黄秋梅,等.社区护理干预在脑卒中合并高血压患者中的应用价值分析及对患者睡眠质量的改善[J].世界睡眠医学杂志,2018,5(6):632-634.
[2]李玲,宋夏,胡汉昆,等.非洛地平联合美托洛尔比较单用非洛地平治疗高血压的疗效与安全性的Meta分析[J].中国药房,2014,4(32):2987-2990.
[3]夏卫,黄静静,王瑞东,等.清脑降压片联合非洛地平缓释片治疗原发性高血压的临床研究[J].现代药物与临床,2016,31(5):628-631.
[4]朱春丽,陈弹.美托洛尔联合非洛地平对高血压患者血压变异和晨峰的影响[J].中西医结合心脑血管病杂志,2013,11(3):279-281.
[5]杨润峰,汪自龙.氯沙坦联合非洛地平治疗轻中度原发性高血压的疗效及其对心功能的影响[J].中国医师进修杂志,2014,37(19):59-61.
[6]朱伟芳,孙嘉曦.高血压病与睡眠障碍的相关性研究[J].实用医学杂志,2014,30(1):139-142.
[7]王否,顾佳怡,徐辉,等.社区综合健康管理对老年高血压患者生命质量的影响[J].中华疾病控制杂志,2018,22(7):708-711,716.
[8]阎善林.硝苯地平辅助治疗老年高血压的临床疗效及对睡眠质量的影响[J].世界睡眠医学杂志,2018,5(6):652-655.
[9]陈青青,陈美佳,黄秋梅,等.社区护理干预在脑卒中合并高血压患者中的应用价值分析及对患者睡眠质量的改善[J].世界睡眠医学杂志,2018,5(6):632-634.