益气通络方治疗输卵管阻塞性不孕症37例
|
摘要
目的:观察益气通络方治疗输卵管阻塞性不孕症的临床疗效及其对患者血液流变学的影响。方法:将74例输卵管阻塞性不孕症患者随机分为对照组和治疗组,每组各37例。对照组患者采用输卵管通液术治疗,治疗组在对照组的基础上联合自拟益气通络方治疗。比较两组患者的临床疗效、输卵管疏通率、妊娠率及治疗前后血液流变学指标。结果:治疗组患者输卵管疏通率、妊娠率均高于对照组,差异具有统计学意义(P<0.05)。对照组有效率为78.79%,治疗组有效率为97.06%,两组患者临床疗效比较,差异具有统计学意义(P<0.05)。两组患者治疗后低切全血黏度、高切全血黏度、血浆黏度、红细胞聚集指数均低于治疗前,且治疗组低于对照组,差异具有统计学意义(P<0.05)。结论:益气通络方治疗输卵管阻塞性不孕症可提高输卵管疏通率、妊娠率,改善血液流变学水平。
Objective:To observe the clinical curative effect of Qi-Boosting and Channel-Unblocking Decoction on fallopian tube obstructive infertility and the patients′ hemorheology.Methods:A total of 74 patients with fallopian tube obstructive infertility were randomly divided into the control group and the treatment group,with 37 cases in each group.The ones in the control group were treated with fallopian tube drainage while the ones in the treatment group were treated with self-made Qi-Boosting and Channel-Unblocking Decoction on the basis of the control group.The clinical efficacy,tubal dredging rate,pregnancy rate and hemorheological level before and after the treatment were compared between the two groups.Results:The tubal dredging rate and pregnancy rate in the treatment group were higher than those in the control group,and the difference was statistically significant(P<0.05).The effective rate of the control group was 78.79%,and that of the treatment group was 97.06%.There was a significant difference between the two groups(P<0.05).After the treatment,the whole blood viscosity of low shear,high shear,plasma viscosity and erythrocyte aggregation index of the two groups were lower than those before the treatment,and the treatment group was lower than the control group,and all the differences were statistically significant(P<0.05).Conclusion:Qi-Boosting and Channel-Unblocking Decoction has a remarkable efficacy on fallopian tube obstructive infertility,can improve the tubal dredging rate,pregnancy rate and the level of hemorheology.
Objective:To observe the clinical curative effect of Qi-Boosting and Channel-Unblocking Decoction on fallopian tube obstructive infertility and the patients′ hemorheology.Methods:A total of 74 patients with fallopian tube obstructive infertility were randomly divided into the control group and the treatment group,with 37 cases in each group.The ones in the control group were treated with fallopian tube drainage while the ones in the treatment group were treated with self-made Qi-Boosting and Channel-Unblocking Decoction on the basis of the control group.The clinical efficacy,tubal dredging rate,pregnancy rate and hemorheological level before and after the treatment were compared between the two groups.Results:The tubal dredging rate and pregnancy rate in the treatment group were higher than those in the control group,and the difference was statistically significant(P<0.05).The effective rate of the control group was 78.79%,and that of the treatment group was 97.06%.There was a significant difference between the two groups(P<0.05).After the treatment,the whole blood viscosity of low shear,high shear,plasma viscosity and erythrocyte aggregation index of the two groups were lower than those before the treatment,and the treatment group was lower than the control group,and all the differences were statistically significant(P<0.05).Conclusion:Qi-Boosting and Channel-Unblocking Decoction has a remarkable efficacy on fallopian tube obstructive infertility,can improve the tubal dredging rate,pregnancy rate and the level of hemorheology.
引文
[1] HOU H Y,CHEN Y Q,LI T C,et al.Outcome of laparoscopy-guided hysteroscopic tubal catheterization for infertility due to proximal tubal obstruction[J].Journal of minimally invasive gynecology,2014,21(2):272-278.
[2] GRIGORESCU V,ZHANG Y,KISSIN D M,et al.Maternal characteristics and pregnancy outcomes after assisted reproductive technology by infertility diagnosis:ovulatory dysfunction versus tubal obstruction[J].Fertility & Sterility,2014,101(4):1019-1025.
[3] 于文朝,芦骏,朱月华,等.输卵管机械疏通联合臭氧注射在输卵管阻塞性不孕症治疗中的应用观察[J].山东医药,2017,57(3):53-55.
[4] 谢幸,苟文丽.妇产科学[M].8版.北京:人民卫生出版社,2013:126-129.
[5] 梁茂新,高天舒.《中药新药临床研究指导原则》脏腑诸证考察与分析[J].中国中医基础医学杂志,2008,14(5):330-331,342.
[6] MICHOU I V,CONSTANTOULAKIS P,MAKAROUNIS K,et al.Molecular investigation of menstrual tissue for the presence of Chlamydia trachomatis,Ureaplasma urealyticum and Mycoplasma hominis collected by women with a history of infertility[J].The journal of obstetrics and gynaecology research,2014,40(1):237-242.
[7] 宗海燕.腹腔镜治疗输卵管阻塞伴盆腔粘连性不孕症的临床疗效[J].中国妇幼保健,2014,29(20):3303-3305.
[8] ZHANG J,KONG Y,FENG Y,et al.Development of a multilocus sequence typing scheme for Ureaplasma[J].European Journal of Clinical Microbiology and Infectious Diseases,2014,33(4):537-544.
[9] 王雅楠,程倩倩,王玉华,等.宫腹腔镜联合RF导丝治疗输卵管阻塞性不孕症98例分析[J].国际生殖健康/计划生育杂志,2017,36(2):103-106.
[10] OLARU O G.Synchronous primary serous ovarian cancer and renal cell carcinoma[J].International Journal of Gynecology and Obstetrics,2014,126(3):282.
[11] 杨兆荣.中医综合疗法治疗输卵管阻塞性不孕症[J].长春中医药大学学报,2015,31(1):154-156.
[12] 汪永平,温勇坚,刘灿,等.中医药联合介入再通治疗输卵管阻塞不孕症临床观察[J].中国中西医结合影像学杂志,2016,14(1):94-96.
[13] 郑凤平,杨国文,孙冬梅,等.温经通络散联合盆炎清栓治疗输卵管阻塞性不孕症43例[J].中国药业,2014,23(2):87-89.
[14] 陈蓉,卢兴宏,樊湘珍,等.砭石热敷治疗输卵管阻塞性不孕症疗效观察[J].湖南中医药大学学报,2017,37(6):652-655.
[15] 张荣,李会学,辛雨玲,等.中医疗法联合介入治疗输卵管阻塞性不孕症50例临床观察[J].河北中医,2014,36(2):232-233.
[16] 刘淑文,王珊珊.椒辛散治疗输卵管通而不畅不孕症临床观察[J].现代中西医结合杂志,2016,25(26):2934-2936.
[2] GRIGORESCU V,ZHANG Y,KISSIN D M,et al.Maternal characteristics and pregnancy outcomes after assisted reproductive technology by infertility diagnosis:ovulatory dysfunction versus tubal obstruction[J].Fertility & Sterility,2014,101(4):1019-1025.
[3] 于文朝,芦骏,朱月华,等.输卵管机械疏通联合臭氧注射在输卵管阻塞性不孕症治疗中的应用观察[J].山东医药,2017,57(3):53-55.
[4] 谢幸,苟文丽.妇产科学[M].8版.北京:人民卫生出版社,2013:126-129.
[5] 梁茂新,高天舒.《中药新药临床研究指导原则》脏腑诸证考察与分析[J].中国中医基础医学杂志,2008,14(5):330-331,342.
[6] MICHOU I V,CONSTANTOULAKIS P,MAKAROUNIS K,et al.Molecular investigation of menstrual tissue for the presence of Chlamydia trachomatis,Ureaplasma urealyticum and Mycoplasma hominis collected by women with a history of infertility[J].The journal of obstetrics and gynaecology research,2014,40(1):237-242.
[7] 宗海燕.腹腔镜治疗输卵管阻塞伴盆腔粘连性不孕症的临床疗效[J].中国妇幼保健,2014,29(20):3303-3305.
[8] ZHANG J,KONG Y,FENG Y,et al.Development of a multilocus sequence typing scheme for Ureaplasma[J].European Journal of Clinical Microbiology and Infectious Diseases,2014,33(4):537-544.
[9] 王雅楠,程倩倩,王玉华,等.宫腹腔镜联合RF导丝治疗输卵管阻塞性不孕症98例分析[J].国际生殖健康/计划生育杂志,2017,36(2):103-106.
[10] OLARU O G.Synchronous primary serous ovarian cancer and renal cell carcinoma[J].International Journal of Gynecology and Obstetrics,2014,126(3):282.
[11] 杨兆荣.中医综合疗法治疗输卵管阻塞性不孕症[J].长春中医药大学学报,2015,31(1):154-156.
[12] 汪永平,温勇坚,刘灿,等.中医药联合介入再通治疗输卵管阻塞不孕症临床观察[J].中国中西医结合影像学杂志,2016,14(1):94-96.
[13] 郑凤平,杨国文,孙冬梅,等.温经通络散联合盆炎清栓治疗输卵管阻塞性不孕症43例[J].中国药业,2014,23(2):87-89.
[14] 陈蓉,卢兴宏,樊湘珍,等.砭石热敷治疗输卵管阻塞性不孕症疗效观察[J].湖南中医药大学学报,2017,37(6):652-655.
[15] 张荣,李会学,辛雨玲,等.中医疗法联合介入治疗输卵管阻塞性不孕症50例临床观察[J].河北中医,2014,36(2):232-233.
[16] 刘淑文,王珊珊.椒辛散治疗输卵管通而不畅不孕症临床观察[J].现代中西医结合杂志,2016,25(26):2934-2936.