脑梗死后抑郁发生的危险因素调查研究
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摘要
目的了解脑梗死后抑郁症(PCID)的发生率及相关因素,为脑梗死患者的心理干预提供理论依据。方法采用汉密尔顿抑郁量表(HAMD)对我院2013年6月~2016年2月220名脑梗死患者进行评分测定,使用调查表收集患者情况,统计分析抑郁症的发生率及影响因素。结果 220例脑梗死患者发生PCID 109例(49.55)%,其中轻度抑郁92例(84.40%),中度抑郁15例(13.76%),重度抑郁2例(1.83%)。二元Logistic逐步回归分析结果:性别为女性(OR=1.80,95%CI:1.25~2.64)、住院时间大于1个月(OR=2.41,95%CI:1.60~5.96)、非首次脑梗死(OR=3.72,95%CI:1.31~8.59)及NIHSS中重度(OR=2.83,95%CI:1.32~4.74)为PCID发生的独立危险因素。结论脑梗死后抑郁发病率较高,可通过调控危险因素予以干预。
Objective This article aims to investigate the incidence and relative risk factors of post-cerebral infarction depression(PCID),in order to provide theoretical evidences for psychological intervention of cerebral infarction. Methods A total of 220 patients with cerebral infarction,who were hospitalized at our hospital from June 2013 to February 2016,were tested by using Hamilton Depression Scale(HAMD).The baseline data of the patients were collected for analyzing the incidence and risk factors of PCID. Results Among 220 cerebral infarction cases,109 cases of them suffered with PCID.The total incidence of PCID was49.54%,including 92 cases with mild depression(84.40%),15 cases with moderate depression(13.76%)and2cases with serious depression(1.83%).Results of stepwise Logistic regression analysis showed the independent risk factors included females(OR =1.80,95%CI :1.25~2.64),hospitalization over a month(OR=2.41,95%CI :1.60~5.96),non-first attack of cerebral infarction(OR =3.72,95%CI :1.31~8.59),and moderate severe NIHSS(OR =2.83,95%CI :1.32~4.74). Conclusion The incidence of PCID was relatively high,which could be intervened by regulating risk factors.
Objective This article aims to investigate the incidence and relative risk factors of post-cerebral infarction depression(PCID),in order to provide theoretical evidences for psychological intervention of cerebral infarction. Methods A total of 220 patients with cerebral infarction,who were hospitalized at our hospital from June 2013 to February 2016,were tested by using Hamilton Depression Scale(HAMD).The baseline data of the patients were collected for analyzing the incidence and risk factors of PCID. Results Among 220 cerebral infarction cases,109 cases of them suffered with PCID.The total incidence of PCID was49.54%,including 92 cases with mild depression(84.40%),15 cases with moderate depression(13.76%)and2cases with serious depression(1.83%).Results of stepwise Logistic regression analysis showed the independent risk factors included females(OR =1.80,95%CI :1.25~2.64),hospitalization over a month(OR=2.41,95%CI :1.60~5.96),non-first attack of cerebral infarction(OR =3.72,95%CI :1.31~8.59),and moderate severe NIHSS(OR =2.83,95%CI :1.32~4.74). Conclusion The incidence of PCID was relatively high,which could be intervened by regulating risk factors.
引文
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[12]Vogel CH.Assessment and approach to treatment in post-stroke depression[J].J Am Acad Nurse Pract,1995,7(10):493-497.
[13]郎延梅.脑梗死后抑郁及其相关影响因素[J].吉林医学,2010,31(28):5050-5051.
[2]Yamada Y,Kato K,Oguri M,et al.Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome[J].Int J Mol Med,2008,21(6):801-808.
[3]黄彩明,王勇健.优质护理对慢性精神分裂症患者心理和康复的影响[J].右江民族医学院学报,2015,37(4):661-662.
[4]徐榛,赵世亮,王少洲,等.急性脑梗死患者同型半胱氨酸水平分析[J].右江民族医学院学报,2016,38(1):9-11.
[5]华文良,汤超,汤文夏.急性中毒与抑郁症相关因素分析[J].右江医学,2014,42(5):570-572.
[6]沈利平,徐桂红,钟月桂,等.脑梗死患者抑郁状况相关分析及护理[J].当代护士:学术版,2008(10):32.
[7]Parodiso S,Robinson RG.Gender differences in poststroke depression[J].J Neuropsychiatry Cin Neurosci,1998,10(1):41-47.
[8]刘艳,余华峰.脑梗死后抑郁及相关因素的研究[J].北京医学,2004,26(3):149.
[9]潘大津,邱伟文,江瑞来,等.脑卒中后抑郁症的发生率及相关因素的研究[J].心血管病防治,2004,4(3):5-7.
[10]郭克锋,关菊香,朱银星.抑郁症患者的治疗难度预测性研究[J].现代康复,2001,5(8):48-49.
[11]陈伟河,熊秀莲,黄丽丹,等.脑梗死后抑郁症多因素分析[J].广东医学,2009,30(4):575-577.
[12]Vogel CH.Assessment and approach to treatment in post-stroke depression[J].J Am Acad Nurse Pract,1995,7(10):493-497.
[13]郎延梅.脑梗死后抑郁及其相关影响因素[J].吉林医学,2010,31(28):5050-5051.