职业性钡化合物中毒105例临床分析
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摘要
<正>钡(Barium,Ba)是一种柔软的、具银白色光泽的碱土金属,钡以毒重石(碳酸钡,Ba CO3)和重晶石(硫酸钡,Ba SO4)的形式存在于自然界。钡化合物广泛应用于陶瓷、玻璃工业、钢材淬火、医用造影剂、农药、化学试剂制作等,常见的钡化合物有氯化钡、碳酸钡、醋酸钡、硝酸钡、硫酸钡、硫化钡、氧化钡、氢氧化钡等。金属钡几乎无毒,钡化合物的毒性与其溶解度有关,可溶性钡化合物有剧毒,碳酸
引文
[1]徐昌盛,刘文革.我国钡中毒的流行病学特征[J].中华劳动卫生职业病杂志,2008,26(12):745-746.
[2]Jacobs I A,Taddeo J,Kelly K,et al.Poisoning as a result of barium styphnate explosion[J].Am J Ind Med,2002,41(4):285-288.
[3]陈长清,鲁锡荣,石佳贵,等.职业性急性钡中毒4例[J].中华劳动卫生职业病杂志,1998,16(4):241-242.
[4]张怡如,庄文英.职业急性碳酸钡中毒抢救治疗体会[J].化工劳动保护(工业卫生与职业病分册),1995,16(3):113-114.
[5]季文锋,周华海.硬脂酸钡中毒8例报告[J].临床荟萃,1999,14(8):357.
[6]吴友林,陈红英.低血钾致严重心律失常的病因分析及抢救[J].江西医药,2005,40(10):638-639.
[7]王丹红,周娟,李菊秀,等.低钾血症发病机制及临床治疗[J].医药前沿,2013,(30):98-99.
[8]Nagel W.Inhibition of potassium conductance by barium in frog skin epithelium[J].Biochem Biophys Acta,1979,552:346-357.
[9]Bhoelan B S,Stevering C H,van der Boog A T,et al.Barium toxicity and the role of the potassium inward rectifier current[J].Clin Toxicol(Phila),2014,52(6):584-593.
[10]Park W S,Han J,Earm Y E.Physiological role of inward rectifier K(+)channels in vascular smooth muscle cells[J].Pflugers Arch,2008,457(1):137-147.
[11]Phelan D M,Hagley S R,Guerin M D.Is hypokalaemia the cause of paralysis in barium poisoning[J].Br Med J(Clin Res Ed),1984,289(6449):882.
[12]Gosselin R E,Smith R P,Hodge H C,et al.Clinical toxicology of commercial products[M].5th ed.Baltimore:Williams and Wilkins,1984:61-62.
[13]陈灏珠,林果为,王吉耀.实用内科学[M].14版.北京:人民卫生出版社,2013:948-949.
[14]谢先会,刘茂英,钟红玲,等.微量泵高浓度大剂量补钾抢救重度低钾血症56例[J].第三军医大学学报,2003,25(13):1215.
[15]王平,王世襄.大剂量补钾、起搏抢救严重缓慢性心律失常伴低血钾症[J].交通医学,1999,13(1):28-29.
[16]Koch M,Appoloni O,Haufriod V,et al.Acute barium intoxication and hemodiafiltration[J].J Toxicol Clin Toxicol,2003,41(4):363-367.
[17]GBZ/T 200.5—2014,辐射防护用参考人第5部分:人体的元素组成和主要组织器官的元素含量[S].
[18]Nordberg G,Fowler B,Nordberg M,et al.Handbook on the Toxicology of Metals[M].3rd edition.USA:Academic Press,2007:407-414.
[19]郭瑞娣,吉钟山,朱醇.钡中毒事件相关样品中钡的检测[J].环境与健康杂志,2008,25(12):1104-1105.
[2]Jacobs I A,Taddeo J,Kelly K,et al.Poisoning as a result of barium styphnate explosion[J].Am J Ind Med,2002,41(4):285-288.
[3]陈长清,鲁锡荣,石佳贵,等.职业性急性钡中毒4例[J].中华劳动卫生职业病杂志,1998,16(4):241-242.
[4]张怡如,庄文英.职业急性碳酸钡中毒抢救治疗体会[J].化工劳动保护(工业卫生与职业病分册),1995,16(3):113-114.
[5]季文锋,周华海.硬脂酸钡中毒8例报告[J].临床荟萃,1999,14(8):357.
[6]吴友林,陈红英.低血钾致严重心律失常的病因分析及抢救[J].江西医药,2005,40(10):638-639.
[7]王丹红,周娟,李菊秀,等.低钾血症发病机制及临床治疗[J].医药前沿,2013,(30):98-99.
[8]Nagel W.Inhibition of potassium conductance by barium in frog skin epithelium[J].Biochem Biophys Acta,1979,552:346-357.
[9]Bhoelan B S,Stevering C H,van der Boog A T,et al.Barium toxicity and the role of the potassium inward rectifier current[J].Clin Toxicol(Phila),2014,52(6):584-593.
[10]Park W S,Han J,Earm Y E.Physiological role of inward rectifier K(+)channels in vascular smooth muscle cells[J].Pflugers Arch,2008,457(1):137-147.
[11]Phelan D M,Hagley S R,Guerin M D.Is hypokalaemia the cause of paralysis in barium poisoning[J].Br Med J(Clin Res Ed),1984,289(6449):882.
[12]Gosselin R E,Smith R P,Hodge H C,et al.Clinical toxicology of commercial products[M].5th ed.Baltimore:Williams and Wilkins,1984:61-62.
[13]陈灏珠,林果为,王吉耀.实用内科学[M].14版.北京:人民卫生出版社,2013:948-949.
[14]谢先会,刘茂英,钟红玲,等.微量泵高浓度大剂量补钾抢救重度低钾血症56例[J].第三军医大学学报,2003,25(13):1215.
[15]王平,王世襄.大剂量补钾、起搏抢救严重缓慢性心律失常伴低血钾症[J].交通医学,1999,13(1):28-29.
[16]Koch M,Appoloni O,Haufriod V,et al.Acute barium intoxication and hemodiafiltration[J].J Toxicol Clin Toxicol,2003,41(4):363-367.
[17]GBZ/T 200.5—2014,辐射防护用参考人第5部分:人体的元素组成和主要组织器官的元素含量[S].
[18]Nordberg G,Fowler B,Nordberg M,et al.Handbook on the Toxicology of Metals[M].3rd edition.USA:Academic Press,2007:407-414.
[19]郭瑞娣,吉钟山,朱醇.钡中毒事件相关样品中钡的检测[J].环境与健康杂志,2008,25(12):1104-1105.