68例老年肺结核患者肠外营养治疗疗效的观察
|
摘要
目的探究肠外营养支持干预应用于老年肺结核病患者对营养状态、不良反应的影响。方法回顾性分析我院2014年1月至2017年10月收治的行常规营养支持的老年肺结核病患者68例,将其作为对照组,回顾性分析我院2014年1月至2017年10月收治的行肠外营养支持干预的老年肺结核病患者68例,将其作为观察组。对比两组干预前后营养状态、免疫能力变化及不良反应发生率。结果观察组干预3周后HGB、TLC、ALB水平均高于对照组,差异有统计学意义(P <0. 05);观察组干预3周后CD_3~+、CD_4~+含量及CD_4~+/CD_8~+均高于对照组,CD_8~+含量低于对照组,差异有统计学意义(P <0. 05);观察组不良反应发生率低于对照组,差异有统计学意义(P <0. 05)。结论肠外营养支持干预应用于老年肺结核病患者可有效改善其营养状态,提高机体免疫力,减少不良反应,有一定应用价值。
Objective To investigate the effect of parenteral nutrition support intervention on nutritional status and adverse reactions in elderly patients with pulmonary tuberculosis. Methods 68 elderly patients with pulmonary tuberculosis who received routine nutritional support from January 2014 to October 2017 in our hospital was selected as the control group,and another 68 elderly patients with pulmonary tuberculosis who received parenteral nutritional support from January 2014 to October 2017 in our hospital were selected as the observation group. Before and after the intervention,their nutritional status,immune capacity changes and the incidence of adverse reactions were compared. Results The levels of HGB,TLC and ALB in the observation group were significantly higher than those in the control group after 3 weeks of intervention( P < 0. 05). The levels of CD_3~+,CDCD_4~+ and CDCD_4~+/CDCD_8~+ in the observation group were significantly higher than those in the control group( P < 0. 05). The incidence of skin rash,vasculitis,fat emulsion and blood glucose elevation in the observation group were lower than those in the control group( P < 0. 05). Conclusion Parenteral nutrition support intervention in elderly patients with pulmonary tuberculosis can effectively improve their nutritional status and immunity,and reduce adverse reactions,which has a certain application value.
Objective To investigate the effect of parenteral nutrition support intervention on nutritional status and adverse reactions in elderly patients with pulmonary tuberculosis. Methods 68 elderly patients with pulmonary tuberculosis who received routine nutritional support from January 2014 to October 2017 in our hospital was selected as the control group,and another 68 elderly patients with pulmonary tuberculosis who received parenteral nutritional support from January 2014 to October 2017 in our hospital were selected as the observation group. Before and after the intervention,their nutritional status,immune capacity changes and the incidence of adverse reactions were compared. Results The levels of HGB,TLC and ALB in the observation group were significantly higher than those in the control group after 3 weeks of intervention( P < 0. 05). The levels of CD_3~+,CDCD_4~+ and CDCD_4~+/CDCD_8~+ in the observation group were significantly higher than those in the control group( P < 0. 05). The incidence of skin rash,vasculitis,fat emulsion and blood glucose elevation in the observation group were lower than those in the control group( P < 0. 05). Conclusion Parenteral nutrition support intervention in elderly patients with pulmonary tuberculosis can effectively improve their nutritional status and immunity,and reduce adverse reactions,which has a certain application value.
引文
[1]李艳霞,钟凯惠,张冬云.抗结核药睡前顿服对改善老年肺结核患者胃肠道不良反应影响的研究[J].护理管理杂志,2016,16(4):276-277.
[2] EOM J S,KIM I,KIM W Y,et al. Household tuberculosis contact investigation in a tuberculosis-prevalent country:are the tuberculin skin test and interferon-gamma release assay enough in elderly contacts[J]. Medicine(Baltimore),2018,97(3):e9681.
[3]刘畅,周向东,李华,等.支气管哮喘合并肺结核患者脑源性神经营养因子和神经激肽A表达对预后的影响分析[J].中华医院感染学杂志,2017,27(4):785-787,791.
[4]康珈宁.抗结核药物治疗老年肺结核患者过程中并发不良反应的护理效果观察[J].中国保健营养,2016,26(5):211-212.
[5]顾静,鱼莉军.老年肺结核患者服药依从性影响因素分析和护理对策探讨[J].中西医结合护理(中英文),2016,2(7):81-82.
[6] DASGUPTA A,FERNANDES L,CHOPRA V,et al. Barriers to building an effective workforce for respiratory research in India:a survey of American Thoracic Society Methods in Epidemiologic,Clinical,and Operations Research India 2017 participants[J].Lung India,2018,35(2):184-186.
[7]余婷.基于“生物-心理-社会”一体化的照护模式护理老年肺结核患者的效果观察[J].国际护理学杂志,2017,36(14):1900-1905.
[8]侯婧,张妍蓓. 536例老年肺结核患者血清白蛋白、血红蛋白等相关指标分析[J].实用医学杂志,2016,32(1):134-136.
[9]侯婧,刘刚,韩莙,等.老年肺结核患者营养指标与疾病相关性分析[J].中国临床研究,2017,30(4):459-462.
[10]李润娜,赵滢.肺结核患者愈后膳食营养及营养相关慢性病预防知识知晓情况的调查[J].中国医药指南,2017,15(6):157-158.
[11] MUTHU V,SEHGAL I S,DHOORIA S,et al. Clinical significance and epidemiological evolution of epitrochlear lymphadenopathy in pre-and post-highly active antiretroviral therapy era:a systematic review of the literature[J]. Lung India,2018,35(2):150-153.
[12]杨飞,于秀丽,宛洋.老年肺结核患者STP、ALB及淋巴细胞水平临床诊疗价值[J].热带医学杂志,2017,17(10):1377-1380.
[13]张辉.老年肺结核患者发生院内感染的危险因素分析[J].临床研究,2016,24(11):135-136.
[14]李润娜,赵滢. 56例老年肺结核合并糖尿病的营养健康教育[J].中国医药指南,2017,15(9):288-289.
[15]邱美华,盛云峰,崔岩飞,等.白介素-17基因多态性与肺结核易感性的相关性研究[J].浙江中西医结合杂志,2017,27(4):303-306.
[16] WORKU S,DERBIE A,MEKONNEN D,et al. Treatment outcomes of tuberculosis patients under directly observed treatment shortcourse at Debre Tabor General Hospital,northwest Ethiopia:nineyears retrospective study[J]. Infect Dis Poverty,2018,7(1):16.
[17]花兴萍,朱蔚岗.胸腺肽α1联合抗结核药治疗老年初治涂阳肺结核患者疗效观察[J].中国保健营养,2016,26(21):243-244.
[2] EOM J S,KIM I,KIM W Y,et al. Household tuberculosis contact investigation in a tuberculosis-prevalent country:are the tuberculin skin test and interferon-gamma release assay enough in elderly contacts[J]. Medicine(Baltimore),2018,97(3):e9681.
[3]刘畅,周向东,李华,等.支气管哮喘合并肺结核患者脑源性神经营养因子和神经激肽A表达对预后的影响分析[J].中华医院感染学杂志,2017,27(4):785-787,791.
[4]康珈宁.抗结核药物治疗老年肺结核患者过程中并发不良反应的护理效果观察[J].中国保健营养,2016,26(5):211-212.
[5]顾静,鱼莉军.老年肺结核患者服药依从性影响因素分析和护理对策探讨[J].中西医结合护理(中英文),2016,2(7):81-82.
[6] DASGUPTA A,FERNANDES L,CHOPRA V,et al. Barriers to building an effective workforce for respiratory research in India:a survey of American Thoracic Society Methods in Epidemiologic,Clinical,and Operations Research India 2017 participants[J].Lung India,2018,35(2):184-186.
[7]余婷.基于“生物-心理-社会”一体化的照护模式护理老年肺结核患者的效果观察[J].国际护理学杂志,2017,36(14):1900-1905.
[8]侯婧,张妍蓓. 536例老年肺结核患者血清白蛋白、血红蛋白等相关指标分析[J].实用医学杂志,2016,32(1):134-136.
[9]侯婧,刘刚,韩莙,等.老年肺结核患者营养指标与疾病相关性分析[J].中国临床研究,2017,30(4):459-462.
[10]李润娜,赵滢.肺结核患者愈后膳食营养及营养相关慢性病预防知识知晓情况的调查[J].中国医药指南,2017,15(6):157-158.
[11] MUTHU V,SEHGAL I S,DHOORIA S,et al. Clinical significance and epidemiological evolution of epitrochlear lymphadenopathy in pre-and post-highly active antiretroviral therapy era:a systematic review of the literature[J]. Lung India,2018,35(2):150-153.
[12]杨飞,于秀丽,宛洋.老年肺结核患者STP、ALB及淋巴细胞水平临床诊疗价值[J].热带医学杂志,2017,17(10):1377-1380.
[13]张辉.老年肺结核患者发生院内感染的危险因素分析[J].临床研究,2016,24(11):135-136.
[14]李润娜,赵滢. 56例老年肺结核合并糖尿病的营养健康教育[J].中国医药指南,2017,15(9):288-289.
[15]邱美华,盛云峰,崔岩飞,等.白介素-17基因多态性与肺结核易感性的相关性研究[J].浙江中西医结合杂志,2017,27(4):303-306.
[16] WORKU S,DERBIE A,MEKONNEN D,et al. Treatment outcomes of tuberculosis patients under directly observed treatment shortcourse at Debre Tabor General Hospital,northwest Ethiopia:nineyears retrospective study[J]. Infect Dis Poverty,2018,7(1):16.
[17]花兴萍,朱蔚岗.胸腺肽α1联合抗结核药治疗老年初治涂阳肺结核患者疗效观察[J].中国保健营养,2016,26(21):243-244.