二甲双胍在妊娠糖尿病治疗中的应用效果分析
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摘要
目的探究二甲双胍在妊娠糖尿病治疗中的应用效果。方法以2017年1月—2018年6月为研究时间段,选取该院妊娠期糖尿病患者96例分为两组,各48例,对照组给予胰岛素治疗,观察组在此基础上应用二甲双胍,对比两组治疗效果及妊娠结局。结果①观察组FPG、2 hPG低于对照组,两组数据差异有统计学意义(P<0.05)。②观察组不良妊娠结局发生率均低于对照组,两组数据差异有统计学意义(P<0.05)。③观察组不良事件发生率均低于对照组,两组数据差异有统计学意义(P<0.05)。结论二甲双胍应用于妊娠糖尿病治疗中,可有效控制血糖,值得推广应用。
Objective To investigate the effect of metformin in the treatment of gestational diabetes. Methods From January2017 to June 2018, 96 patients with gestational diabetes mellitus in our hospital were divided into two groups, 48 in each group. The control group was given insulin therapy. The observation group used metformin on this basis. The treatment effect and pregnancy outcome of the two groups were compared. Results 1.The FPG and 2 hPG in the observation group were lower than the control group, and the data of the two groups were significantly different(P<0.05), which was statistically significant. 2.The incidence of adverse pregnancy outcomes in the observation group was lower than that in the control group,and the difference between the two groups was significant(P <0.05). 3.The incidence of adverse events in the observation group was lower than that in the control group. The difference between the two groups was significant(P<0.05), which was statistically significant. Conclusion Metformin is effective in the control of gestational diabetes and is worthy of popularization and application.
Objective To investigate the effect of metformin in the treatment of gestational diabetes. Methods From January2017 to June 2018, 96 patients with gestational diabetes mellitus in our hospital were divided into two groups, 48 in each group. The control group was given insulin therapy. The observation group used metformin on this basis. The treatment effect and pregnancy outcome of the two groups were compared. Results 1.The FPG and 2 hPG in the observation group were lower than the control group, and the data of the two groups were significantly different(P<0.05), which was statistically significant. 2.The incidence of adverse pregnancy outcomes in the observation group was lower than that in the control group,and the difference between the two groups was significant(P <0.05). 3.The incidence of adverse events in the observation group was lower than that in the control group. The difference between the two groups was significant(P<0.05), which was statistically significant. Conclusion Metformin is effective in the control of gestational diabetes and is worthy of popularization and application.
引文
[1]王东霞.二甲双胍治疗多囊卵巢综合征的临床效果观察[J].中国农村卫生,2016,31(16):34.
[2]陆世霞.分析二甲双胍治疗青春期多囊卵巢综合征的疗效[J].医学理论与实践,2015,22(1):45.
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[4]李梅.妊娠合并糖尿病酮症酸中毒病例分析[J].世界最新医学信息文摘,2016,34(47):44.
[5]王晨,杨慧霞.妊娠合并糖尿病诊治研究进展[J].中国全科医学,2016,44(32):66.
[6]刘艳.浅谈妊娠合并糖尿病的临床治疗[J].临床医药文献电子杂志,2017,22(5):344.
[2]陆世霞.分析二甲双胍治疗青春期多囊卵巢综合征的疗效[J].医学理论与实践,2015,22(1):45.
[3]陈桂红.二甲双胍治疗多囊卵巢综合征的临床分析[J].大家健康:学术版,2015,33(6):155.
[4]李梅.妊娠合并糖尿病酮症酸中毒病例分析[J].世界最新医学信息文摘,2016,34(47):44.
[5]王晨,杨慧霞.妊娠合并糖尿病诊治研究进展[J].中国全科医学,2016,44(32):66.
[6]刘艳.浅谈妊娠合并糖尿病的临床治疗[J].临床医药文献电子杂志,2017,22(5):344.