介入技术治疗缺血性脑血管疾病的临床疗效
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摘要
目的探讨介入技术治疗缺血性脑血管疾病的临床疗效。方法选择2013年1月~2014年12月在我院治疗的缺血性脑血管病患者158例的临床资料进行回顾性分析。其中71例采用介入治疗为介入组,87例采用单纯药物治疗为对照组。比较两组的临床疗效。结果介入组在治疗3 d后狭窄血管Vs较治疗前显著下降,差异有高度统计学意义(P<0.01),并且在治疗12个月时维持在治疗后3 d相似的水平,差异无统计学意义(P>0.05)。两组间比较,介入组在治疗后3 d及治疗后12个月,狭窄血管的Vs均显著低于对照组,差异有高度统计学意义(P<0.01)。介入组脑梗死患者在治疗后1个月,NIHSS评分就显著下降,与治疗前比较,差异有高度统计学意义(P<0.01);介入组脑梗死患者在治疗后1个月、6个月及12个月NIHSS评分均显著低于对照组,差异有高度统计学意义(P<0.01)。结论缺血性脑血管疾病采用介入技术治疗能够及时改善狭窄血管,恢复缺血区血供,改善患者近期及远期预后,尤其对脑梗死患者,能够改善患者神经功能缺损情况。
Objective To discuss the clinical efficacy of interventional therapy for ischemic cerebrovascular diseases.Methods Clinical data of 158 cases with ischemic cerebrovascular disease from Jan 2013 to Dec 2014 were respectively analyzed. 71 cases were treated with interventional therapy were interventional group, and 87 cases were treated with simple drugs treatment were control group. Clinical efficacy of two groups was compared. Results Narrow blood vessel Vs of interventional group after treatment of 3 d were lower than before treatment(P<0.01), and Vs of interventional group after treatment of 3 d showed no significant difference with after treatment of 12 months(P>0.05). Vs levels of in terventional group after treatment of 3 d and after treatment of 12 months were lower than control group(P <0.01).NIHSS of interventional group after treatment of 1 month was lower than that before treatment(P<0.01). NIHSS of interventional group after treatment of 1 month, 6 months and 12 months were lower than control group(P<0.01). Conclusion Interventional therapy for ischemic cerebrovascular diseases can improve the narrow blood vessel in time, recovery of blood supply in ischemic area, improving the short-term and long-term prognosis of patients, especially for patients with cerebral infarction, which can improve the neurological function of patients.
Objective To discuss the clinical efficacy of interventional therapy for ischemic cerebrovascular diseases.Methods Clinical data of 158 cases with ischemic cerebrovascular disease from Jan 2013 to Dec 2014 were respectively analyzed. 71 cases were treated with interventional therapy were interventional group, and 87 cases were treated with simple drugs treatment were control group. Clinical efficacy of two groups was compared. Results Narrow blood vessel Vs of interventional group after treatment of 3 d were lower than before treatment(P<0.01), and Vs of interventional group after treatment of 3 d showed no significant difference with after treatment of 12 months(P>0.05). Vs levels of in terventional group after treatment of 3 d and after treatment of 12 months were lower than control group(P <0.01).NIHSS of interventional group after treatment of 1 month was lower than that before treatment(P<0.01). NIHSS of interventional group after treatment of 1 month, 6 months and 12 months were lower than control group(P<0.01). Conclusion Interventional therapy for ischemic cerebrovascular diseases can improve the narrow blood vessel in time, recovery of blood supply in ischemic area, improving the short-term and long-term prognosis of patients, especially for patients with cerebral infarction, which can improve the neurological function of patients.
引文
[1]卫杰,耿昌明,韦道明,等.介入技术治疗缺血性脑血管疾病49例疗效观察[J].海军医学杂志,2016,37(1):47-50.
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[5]李旭,张飚,曹沁梅,等.急性缺血性脑卒中患者血清Apo B/Apo A 1与NIHSS评分的相关性[J].山东医药,2015,55(10):11-13.
[6]朱峰,刘晨溪,姬中庆,等.介入溶栓术治疗超早期急性闭塞性脑梗死对患者神经功能及生活质量恢复的影响[J].临床合理用药杂志,2015,8(31):31-33.
[7]邹蓉,曲晓宁,周艳玲,等.介入技术治疗缺血性脑血管疾病的疗效观察[J].湖南师范大学学报:医学版,2015,12(3):62-64.
[8]朱峰,刘晨溪,姬中庆,等.介入溶栓术治疗超早期急性闭塞性脑梗死对患者血清BNP、Hcy及PPARγ水平的影响[J].临床合理用药杂志,2015,8(28):114-115.
[9]王贺,张逊娟.不同介入方法治疗急性脑梗死的临床效果观察[J].中国卫生标准管理,2015,6(23):52-53.
[10]姜海波,曹辉.介入治疗对脑梗死伴重度颈动脉狭窄患者近期预后的影响[J].中国实用神经疾病杂志,2015,18(16):51-52.
[11]韩洪武.血管介入治疗急性脑梗死的疗效及对纤溶性水平的影响[J].广东微量元素科学,2015,22(6):64-67.
[12]张怀昳.对急性脑梗死患者进行动脉介入治疗的效果观察[J].当代医药论丛,2015,13(11):291-292.
[13]杨波,徐建银.急性前循环脑梗死老年患者准介入溶栓治疗疗效及安全性[J].中国实用医药,2015,10(16):176-177.
[14]董先成,郎清,陈忠,等.急性脑梗死患者介入治疗的疗效及对患者纤溶系统的影响[J].现代生物医学进展,2015,15(15):2900-2903.
[15]李瑞军.动脉溶栓介入治疗老年急性颈内动脉系统脑梗死临床观察[J].中国现代药物应用,2015,9(8):137-138.
[2]周宇艺.急性脑梗死患者在早期康复治疗不同介入时机的临床疗效比较[J].实用医技杂志,2016,23(1):83-84.
[3]王贺,张逊娟.血管内介入治疗后循环急性脑梗死效果分析[J].中国现代药物应用,2015,9(23):139-140.
[4]朱峰,刘晨溪,姬中庆,等.介入溶栓术治疗急性闭塞性脑梗死的最佳时机探讨[J].临床合理用药杂志,2015,8(34):126-127.
[5]李旭,张飚,曹沁梅,等.急性缺血性脑卒中患者血清Apo B/Apo A 1与NIHSS评分的相关性[J].山东医药,2015,55(10):11-13.
[6]朱峰,刘晨溪,姬中庆,等.介入溶栓术治疗超早期急性闭塞性脑梗死对患者神经功能及生活质量恢复的影响[J].临床合理用药杂志,2015,8(31):31-33.
[7]邹蓉,曲晓宁,周艳玲,等.介入技术治疗缺血性脑血管疾病的疗效观察[J].湖南师范大学学报:医学版,2015,12(3):62-64.
[8]朱峰,刘晨溪,姬中庆,等.介入溶栓术治疗超早期急性闭塞性脑梗死对患者血清BNP、Hcy及PPARγ水平的影响[J].临床合理用药杂志,2015,8(28):114-115.
[9]王贺,张逊娟.不同介入方法治疗急性脑梗死的临床效果观察[J].中国卫生标准管理,2015,6(23):52-53.
[10]姜海波,曹辉.介入治疗对脑梗死伴重度颈动脉狭窄患者近期预后的影响[J].中国实用神经疾病杂志,2015,18(16):51-52.
[11]韩洪武.血管介入治疗急性脑梗死的疗效及对纤溶性水平的影响[J].广东微量元素科学,2015,22(6):64-67.
[12]张怀昳.对急性脑梗死患者进行动脉介入治疗的效果观察[J].当代医药论丛,2015,13(11):291-292.
[13]杨波,徐建银.急性前循环脑梗死老年患者准介入溶栓治疗疗效及安全性[J].中国实用医药,2015,10(16):176-177.
[14]董先成,郎清,陈忠,等.急性脑梗死患者介入治疗的疗效及对患者纤溶系统的影响[J].现代生物医学进展,2015,15(15):2900-2903.
[15]李瑞军.动脉溶栓介入治疗老年急性颈内动脉系统脑梗死临床观察[J].中国现代药物应用,2015,9(8):137-138.