居家化疗肺结核患者服药依从性及其影响因素研究
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摘要
目的分析居家化疗肺结核患者服药依从性现状及影响因素,为制定有针对性地提高其服药依从性的措施提供依据。方法采用整群抽样法,抽取2015年7—12月在咸阳市2区10县登记的居家化疗肺结核患者,共253名。采用Morisky服药依从性量表、自行设计的一般资料调查表和肺结核防治知识调查表对其进行问卷调查,采用χ2检验和多因素logistic回归分析。结果患者服药依从性平均得分为(5.6±1.8)分;依从性良好者138名(54.5%),依从性差者115名(45.5%)。家庭月收入、居住方式和服药督导方式是其服药依从性的影响因素(P<0.05)。结论咸阳市居家化疗肺结核患者服药依从性不高,建议进一步降低家庭经济条件较差患者的经济负担,鼓励患者尽量与亲友同居,并发挥家属督导作用。
Objective To explore medication compliance and influencing factors of pulmonary tuberculosis patients underwent domiciliary chemotherapy,provide evidence for developing targeted measures to improve the medication compliance.Methods A total of 253 pulmonary tuberculosis patients underwent domiciliary chemotherapy registered in 10 counties,2 districts in Xianyang from July to December 2015 were recruited by cluster sampling.Morisky medication compliance scale,self-designed general information questionnaire,tuberculosis prevention knowledge questionnaire were used to conduct the questionnaire survey.χ2 test and logistic regression model were used to identify risk factors. Results The average score of medication compliance was 5.6±1.8;there were 138 patients(54.5%)with good compliance and 115 patients(45.5%)with poor compliance.Family monthly income,living style and medication supervision style were the influencing factors of medication compli-ance(P<0.05). Conclusion Medication compliance of pulmonary tuberculosis patients underwent domiciliary chemotherapyin Xianyang is poor.Tuberculosis control dispensary should take measures to reduce economic burden of the poor,encourage patients to live with relatives or friends,and fully play the role of family supervision.
Objective To explore medication compliance and influencing factors of pulmonary tuberculosis patients underwent domiciliary chemotherapy,provide evidence for developing targeted measures to improve the medication compliance.Methods A total of 253 pulmonary tuberculosis patients underwent domiciliary chemotherapy registered in 10 counties,2 districts in Xianyang from July to December 2015 were recruited by cluster sampling.Morisky medication compliance scale,self-designed general information questionnaire,tuberculosis prevention knowledge questionnaire were used to conduct the questionnaire survey.χ2 test and logistic regression model were used to identify risk factors. Results The average score of medication compliance was 5.6±1.8;there were 138 patients(54.5%)with good compliance and 115 patients(45.5%)with poor compliance.Family monthly income,living style and medication supervision style were the influencing factors of medication compli-ance(P<0.05). Conclusion Medication compliance of pulmonary tuberculosis patients underwent domiciliary chemotherapyin Xianyang is poor.Tuberculosis control dispensary should take measures to reduce economic burden of the poor,encourage patients to live with relatives or friends,and fully play the role of family supervision.
引文
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[11]袁云,平杨,徐凌忠.初治肺结核患者服药依从性的相关因素分析[J].医学与哲学,2014,35(2B):42-44.
[12]崔伊萌,徐凌忠,王兴洲,等.山东省居家化疗肺结核病患者服药依从性相关因素分析[J].中国卫生统计,2013,30(6):872-873.
[13]陈松华,何铁牛,张明五,等.浙江省结核患者疾病负担调查分析[J].中国公共卫生管理,2014,34(2):839-841.
[14]高旭东,张平,孔婵,等.肺结核巩固期患者服药依从性及其影响因素研究[J].护理学报,2012,19(12A):12-15.
[15]殷玉华,李正直,乔慧,等.宁夏贫困县确诊结核患者服药依从性现状及其影响因素[J].中国公共卫生,2015,31(11):1433-1436.
[16]林定文.肺结核患者治疗依从性研究进展[J].热带医学杂志,2014,14(7):973-974.
[2]TANG Y,ZHAO M,WANG Y,et al.Non-adherence to anti-tuberculosis treatment among internal migrants with pulmonary tuberculosis in Shenzhen,China:a cross-sectional study[J].BMC Public Health,2015,15:474.
[3]鹂桂青,高翠南,何庆秋.肺结核病患者治疗依从性的研究进展[J].中国防痨杂志,2010,32(9):585-587.
[4]TESFAHUNEYGN G,MEDHIN G,LEGESSE M.Adherence to antituberculosis treatment and treatment outcomes among tuberculosis patients in Alamata District,northeast Ethiopia[J].BMC Res Notes,2015,8:503.
[5]王晓红.山东省肺结核病人服药依从性现状及其影响因素研究[D].济南:山东大学,2013.
[6]全国第五次结核病流行病学抽样调查技术指导组.2010年全国第五次结核病流行病学抽样调查报告[J].中国防痨杂志,2012,34(8):485-508.
[7]马艳,刘宇红,杜建,等.肺结核患者结核病防治知识核心信息知晓情况调查[J].中国防痨杂志,2015,37(10):8-45.
[8]高旭东.肺结核巩固治疗期患者服药依从性的现况及干预效果的研究[D].衡阳:南华大学,2013.
[9]张斯钰,白丽琼,谭红专,等.Morisky服药依从性量表在肺结核患者中的应用[J].中国防痨杂志,2010,32(9):527-530.
[10]陈妙玉,莫实德.肺结核患者治疗依从性及其影响因素[J].广西医学,2015,37(1):78-81.
[11]袁云,平杨,徐凌忠.初治肺结核患者服药依从性的相关因素分析[J].医学与哲学,2014,35(2B):42-44.
[12]崔伊萌,徐凌忠,王兴洲,等.山东省居家化疗肺结核病患者服药依从性相关因素分析[J].中国卫生统计,2013,30(6):872-873.
[13]陈松华,何铁牛,张明五,等.浙江省结核患者疾病负担调查分析[J].中国公共卫生管理,2014,34(2):839-841.
[14]高旭东,张平,孔婵,等.肺结核巩固期患者服药依从性及其影响因素研究[J].护理学报,2012,19(12A):12-15.
[15]殷玉华,李正直,乔慧,等.宁夏贫困县确诊结核患者服药依从性现状及其影响因素[J].中国公共卫生,2015,31(11):1433-1436.
[16]林定文.肺结核患者治疗依从性研究进展[J].热带医学杂志,2014,14(7):973-974.