硫酸镁与孟鲁司特联用于小儿支气管哮喘的临床治疗价值
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摘要
目的探讨硫酸镁与孟鲁司特联合治疗小儿支气管哮喘的临床疗效。方法选取支气管哮喘患儿60例,随机分为对照组和观察组各30例。对照组采用硫酸镁单一治疗,观察组采用硫酸镁与孟鲁司特联合治疗;对比分析两组患儿的临床治疗效果。结果分别经临床有效治疗后,观察组总有效率高于对照组,且其FVC、PEFR、FEV1均高于对照组,组间比较差异具有统计学意义(P<0.05);两组不良反应发生率差异无统计学意义(P>0.05)。结论硫酸镁与孟鲁司特两药联用治疗小儿支气管哮喘疗效好、安全性高。
Objective To explore the clinical efficacy of magnesium sulfate combined with montelukast in the treatment of bronchial asthma in children. Methods 60 children with bronchial asthma were selected and randomly divided into control group and observation group, 30 cases in each group. The control group was treated with magnesium sulfate alone, and the observation group was treated with magnesium sulfate and montelukast. The clinical effects of two groups were compared. ResultsAfter effective treatment, the total effective rate of the observation group was significantly higher than that of the control group, and the FVC, PEFR and FEV1 were significantly higher than those in the control group, and the difference between the groups was statistically significant(P < 0.05); there was no significant difference in the incidence of adverse reactions between the two groups(P > 0.05). Conclusion The combination of magnesium sulfate and montelukast in the treatment of bronchial asthma in children is effective and safe.
Objective To explore the clinical efficacy of magnesium sulfate combined with montelukast in the treatment of bronchial asthma in children. Methods 60 children with bronchial asthma were selected and randomly divided into control group and observation group, 30 cases in each group. The control group was treated with magnesium sulfate alone, and the observation group was treated with magnesium sulfate and montelukast. The clinical effects of two groups were compared. ResultsAfter effective treatment, the total effective rate of the observation group was significantly higher than that of the control group, and the FVC, PEFR and FEV1 were significantly higher than those in the control group, and the difference between the groups was statistically significant(P < 0.05); there was no significant difference in the incidence of adverse reactions between the two groups(P > 0.05). Conclusion The combination of magnesium sulfate and montelukast in the treatment of bronchial asthma in children is effective and safe.
引文
[1]李群.孟鲁司特钠治疗小儿支气管哮喘的临床疗效观察[J].中国医药指南,2017,15(7):5-6.
[2]刘月霞.硫酸镁联合孟鲁司特治疗小儿支气管哮喘临床效果分析[J].中国伤残医学,2016,24(2):112-113.
[3]李静.小儿支气管哮喘急性发作治疗的护理探讨[J].医药与保健,2015,23(4):117.
[4]李德铭.硫酸镁联合孟鲁司特治疗小儿支气管哮喘临床效果分析[J].现代诊断与治疗,2015,26(6):1295-1296.
[5]娄兴旺,梁玉巧.探讨孟鲁司特治疗小儿支气管哮喘的临床疗效[J].中国卫生标准管理,2014,5(2):40-41.
[6]张鹤.硫酸镁与孟鲁司特对小儿支气管哮喘的治疗效果分析[J].中国继续医学教育,2016,8(9):136-137.
[7]林国金.小儿支气管哮喘200例临床分析[J].中外医学研究,2015,13(31):135-136.
[8]梁小步.孟鲁司特钠联合硫酸镁治疗小儿支气管哮喘的疗效[J].实用临床医学,2016,17(10):48-50.
[9]叶竹梅.小儿支气管哮喘临床治疗研究进展[J].中国乡村医药,2015,22(5):85-86.
[10]殷海燕.硫酸镁联合孟鲁司特治疗小儿支气管哮喘的疗效观察[J].中国医药指南,2017,15(12):60-61.
[11]杨丽萍.150例小儿过敏性支气管哮喘发病因素分析[J].中国卫生产业,2016,13(9):82-84.
[12]李书娟,高莹,陈彤,等.小儿支气管哮喘的诱因分析与临床研究[J].中国医药指南,2016,14(26):186-187.
[2]刘月霞.硫酸镁联合孟鲁司特治疗小儿支气管哮喘临床效果分析[J].中国伤残医学,2016,24(2):112-113.
[3]李静.小儿支气管哮喘急性发作治疗的护理探讨[J].医药与保健,2015,23(4):117.
[4]李德铭.硫酸镁联合孟鲁司特治疗小儿支气管哮喘临床效果分析[J].现代诊断与治疗,2015,26(6):1295-1296.
[5]娄兴旺,梁玉巧.探讨孟鲁司特治疗小儿支气管哮喘的临床疗效[J].中国卫生标准管理,2014,5(2):40-41.
[6]张鹤.硫酸镁与孟鲁司特对小儿支气管哮喘的治疗效果分析[J].中国继续医学教育,2016,8(9):136-137.
[7]林国金.小儿支气管哮喘200例临床分析[J].中外医学研究,2015,13(31):135-136.
[8]梁小步.孟鲁司特钠联合硫酸镁治疗小儿支气管哮喘的疗效[J].实用临床医学,2016,17(10):48-50.
[9]叶竹梅.小儿支气管哮喘临床治疗研究进展[J].中国乡村医药,2015,22(5):85-86.
[10]殷海燕.硫酸镁联合孟鲁司特治疗小儿支气管哮喘的疗效观察[J].中国医药指南,2017,15(12):60-61.
[11]杨丽萍.150例小儿过敏性支气管哮喘发病因素分析[J].中国卫生产业,2016,13(9):82-84.
[12]李书娟,高莹,陈彤,等.小儿支气管哮喘的诱因分析与临床研究[J].中国医药指南,2016,14(26):186-187.