摘要
目的分析老年急性ST段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入手术(PCI)后支架内再狭窄的危险因素。方法回顾性分析93例经PCI手术治疗的老年急性STEMI患者的临床资料,基于PCI术后是否出现支架内再狭窄将患者分为出现组和未出现组。分析术后支架内再狭窄的危险因素。结果 93例患者中,术后出现支架内再狭窄的有21例,未出现的有72例,出现率为22.58%。单因素分析显示,出现组的BMI≥24.00 kg/m2、高血压、糖尿病、病变支数≥2、TG≥2.20 mmol/L、FIB≥3.80 g/L占比显著高于未出现组(P<0.05);且多因素Logistic回归分析发现,上述因素均为患者出现支架内再狭窄的独立危险因素(P<0.05)。结论高BMI、高血压、糖尿病、病变支数多、高TG、高FIB是老年急性STEMI患者PCI术后支架内再狭窄的危险因素,在临床处理中需采取针对性预防措施,减少支架内再狭窄,改善手术预后。
Objective To analyze the risk factors for in-stent restenosis in elderly patients with acute ST-segment elevation myocardial infarction(STEMI) after percutaneous coronary intervention(PCI). Methods The clinical data of 93 elderly patients with acute STEMI treated by PCI were retrospectively analyzed. Based on whether in-stent restenosis occurred after PCI, the patients were divided into emergent group and non-emergent group. The risk factors of in-stent restenosis after surgery were analyzed. Results Among 93 patients, 21 cases had stent restenosis, 72 cases didn't have stent restenosis, and the occurrence rate was 22.58%. The univariate analysis showed that BMI ≥24.00 kg/m2, hypertension,diabetes mellitus, number of lesion branches ≥2, TG ≥2.20 mmol/L and FIB ≥3.80 g/L in the presence group were significantly higher than those in the absence group(P<0.05), and the multivariate Logistic regression analysis showed that the above factors were independent risk factors for in-stent restenosis(P <0.05). Conclusion High BMI, hypertension,diabetes mellitus, more lesion branches, high TG and high FIB are the risk factors for in-stent restenosis in elderly patients with acute STEMI after PCI. Targeted preventive measures should be taken in clinical treatment to reduce in-stent restenosis and improve the prognosis of surgery.
引文
[1]李承刚,夏勇,高雯,等.不同血管的急性下壁心肌梗死老年患者直接PCI术后短期预后分析[J].中国医药导报,2017,14(14):56-59.
[2]沈卫峰,张奇,张瑞岩.2015年急性ST段抬高型心肌梗死诊断和治疗指南解析[J].国际心血管病杂志,2015,42(4):217-219.
[3]杨琴,张建起,张梅,等.STEMI患者急诊PCI术前H-FABP水平与预后的关系[J].天津医药,2017,45(11):1157-1161.
[4]俞晓雯.急性ST段抬高型心肌梗死患者PCI术后心房颤动发生的预测因素[J].山东医药,2018,58(17):55-57.
[5]龚福汉,刘浙波,夏豪.经皮冠状动脉介入术后支架内再狭窄的相关危险因素分析[J].中华实用诊断与治疗杂志,2017,31(5):461-463.
[6]邓婵翠,邓文文,许官学,等.冠心病PCI术后支架内再狭窄的相关因素分析[J].中国动脉硬化杂志,2017,25(3):278-283.
[7]赵华,张建军.经皮冠状动脉介入术后1年支架内再狭窄的原因分析[J].西南国防医药,2017,27(4):329-332.
[8]程石.冠心病合并糖尿病患者冠状动脉药物洗脱支架置入后支架内再狭窄危险因素分析[J].中国循证心血管医学杂志,2017,9(1):95-98.