后牙双斜面导板矫治器对生长期大鼠下颌形态的影响
|
摘要
目的:探讨后牙双斜面导板矫治器(TIPA)对生长期大鼠下颌骨不同部位形态的影响。方法:应用自行设计的TIPA引导6周龄大鼠下颌后退。测量实验组和对照组大鼠在3,14,30和60 d时髁突和下颌骨不同部位的形态。结果:TIPA实验组在30 d:下颌的长度(A-F)、髁突的长度(B-F)和髁骨长度(C-D)明显变短,有统计学差异(P<0. 05),并持续到第60天。髁突长轴与下颌平面的交角(BF/GH)明显变大,有统计学差异(P<0. 01)。TIPA实验组在60 d,髁突宽度(Q-R)变短,有统计学差异(P<0. 05)。在30 d和60 d,TIPA实验组髁突的后表面变平。在整个观察期间(60 d),下颌基骨的长度(A-B)和从点C,F到GH的距离,TIPA实验组和对照组无统计学差异(P>0. 05)。结论:TIPA能有效抑制生长期大鼠髁突长度和下颌长度的生长。
Objective: To investigate the morphological effects of Twin Inclined Plane Appliance(TIPA)on the different parts of mandible in growing rats.Methods: The self-designed TIPA was used to induce backward movement of mandible in 6-week-old rats. The morphology of different parts of mandible on 3, 14, 30 and 60 days were measured in experimental and control groups.Results: The mandibular length(A-F), the length of condylarprocess(B-F) and the length of condyle(C-D) were significantly decreased on day 30 and remained so on day 60 in the experimental group. The angle of condylar process axis to mandibular plane(BF/GH) increased significantly on day 30(P<0. 01). On day 60, the width of condyle(Q-R) was decreased significantly in the experimental group(P<0. 05). On day 30 and 60, the posterior surface of the condyle became flattenedin the experimental group. During the whole observation period(60 days), the length of mandibular base(A-B), the distance from point C to GH line and the distance from point F to GH line showed no significant differences between the experimental and control groups(P>0. 05).Conclusions: TIPA can effectively inhibit the growth of condylar length and mandibular length in growing rats.
Objective: To investigate the morphological effects of Twin Inclined Plane Appliance(TIPA)on the different parts of mandible in growing rats.Methods: The self-designed TIPA was used to induce backward movement of mandible in 6-week-old rats. The morphology of different parts of mandible on 3, 14, 30 and 60 days were measured in experimental and control groups.Results: The mandibular length(A-F), the length of condylarprocess(B-F) and the length of condyle(C-D) were significantly decreased on day 30 and remained so on day 60 in the experimental group. The angle of condylar process axis to mandibular plane(BF/GH) increased significantly on day 30(P<0. 01). On day 60, the width of condyle(Q-R) was decreased significantly in the experimental group(P<0. 05). On day 30 and 60, the posterior surface of the condyle became flattenedin the experimental group. During the whole observation period(60 days), the length of mandibular base(A-B), the distance from point C to GH line and the distance from point F to GH line showed no significant differences between the experimental and control groups(P>0. 05).Conclusions: TIPA can effectively inhibit the growth of condylar length and mandibular length in growing rats.
引文
[1]Sasaguri K,Jiang H,Chen J.The effect of altered functional forces on the expression of bone-matrix proteins in developing mouse mandibular condyle[J].Arch Oral Biol,1998,43(1):83-92.
[2]王硕,华先明.下颌髁突软骨的生化组成和在压缩负荷作用下的生化机械性能[J].广东牙病防治,2015,23(10):550-552.Wang S,Hua XM.The Biochemical composition of mandibular condylar cartilage and biochemical mechanical properties under compressive load[J].Journal of Prevention and Treatment for Stomatological Diseases,2015,23(10):550-552.
[3]华先明,夏大弘,韩光丽.下颌渐进式后退动物模型的建立[J].口腔医学研究,2012,28(10):983-986.Hua XM,Xia DH,Han GL.Establishment of animal model of gradually induced backward movement of mandible[J].Journal of Oral Science Research,2012,28(10):983-986.
[4]汪喻忠,夏大弘,韩光丽,等.下颌渐进式后退对髁突软骨厚度的影响[J].武汉大学学报:医学版,2016,37(2):270-272.Wang YZ,Xia DH,Han GL,et al.Effect of mandibular progressive retrusion on the thickness of mandibular condylar cartilage[J].Medical Journal of Wuhan University,2016,37(2):270-272.
[5]Xiong H,Hagg U,Tang GH,et al.The effect of continuous bite-jumping in adult rats:a morphological study[J].Angle Orthod,2004,74(1):86-92.
[6]Maki K,Nishioka T,Shioiri E,et al.Effects of dietary consistency on the mandible of rats at the growth stage:computed X-ray densitometric and cephalometric analysis[J].Angle Orthod,2002,72(5):468-475.
[7]Tuominen M,Kantomaa T,Pirttiniemi P.Effect of altered loading on condylar growth in the rat[J].Acta Odontol Scand,1994,52(3):129-134.
[8]Kilaridis S.Muscle function as a determinant of mandibular growth in normal and hypocalcaemic rat[J].Eur JOrthod,1989,11(3):298-308.
[9]Akagawa Y,Nikai H,Tsuru H.Histologic changes in rat masticatory muscles subsequent to experimental increase of the occlusal vertical dimension[J].J Prosthet Dent,1983,50(5):725-732.
[10]Yabushita T,Zeredo JL,Toda K,et al.Role of occlusal vertical dimension in spindle function[J].J Dent Res,2005,84(3):245-249.
[11]Mcnamara JA Jr,Bryan FA.Long-term mandibular adaptations to protrusive function:an experimental study in Macaca mulatta[J].Am J Orthod Dentofacial Orthop,1987,92(2):98-108.
[12]Kuboki T,Shinoda M,Orsini MG,et al.Viscoelastic properties of the pig temporomandibular joint articular soft tissues of the condyle and disc[J].J Dent Res,1997,76(11):1 760-1 769.
[2]王硕,华先明.下颌髁突软骨的生化组成和在压缩负荷作用下的生化机械性能[J].广东牙病防治,2015,23(10):550-552.Wang S,Hua XM.The Biochemical composition of mandibular condylar cartilage and biochemical mechanical properties under compressive load[J].Journal of Prevention and Treatment for Stomatological Diseases,2015,23(10):550-552.
[3]华先明,夏大弘,韩光丽.下颌渐进式后退动物模型的建立[J].口腔医学研究,2012,28(10):983-986.Hua XM,Xia DH,Han GL.Establishment of animal model of gradually induced backward movement of mandible[J].Journal of Oral Science Research,2012,28(10):983-986.
[4]汪喻忠,夏大弘,韩光丽,等.下颌渐进式后退对髁突软骨厚度的影响[J].武汉大学学报:医学版,2016,37(2):270-272.Wang YZ,Xia DH,Han GL,et al.Effect of mandibular progressive retrusion on the thickness of mandibular condylar cartilage[J].Medical Journal of Wuhan University,2016,37(2):270-272.
[5]Xiong H,Hagg U,Tang GH,et al.The effect of continuous bite-jumping in adult rats:a morphological study[J].Angle Orthod,2004,74(1):86-92.
[6]Maki K,Nishioka T,Shioiri E,et al.Effects of dietary consistency on the mandible of rats at the growth stage:computed X-ray densitometric and cephalometric analysis[J].Angle Orthod,2002,72(5):468-475.
[7]Tuominen M,Kantomaa T,Pirttiniemi P.Effect of altered loading on condylar growth in the rat[J].Acta Odontol Scand,1994,52(3):129-134.
[8]Kilaridis S.Muscle function as a determinant of mandibular growth in normal and hypocalcaemic rat[J].Eur JOrthod,1989,11(3):298-308.
[9]Akagawa Y,Nikai H,Tsuru H.Histologic changes in rat masticatory muscles subsequent to experimental increase of the occlusal vertical dimension[J].J Prosthet Dent,1983,50(5):725-732.
[10]Yabushita T,Zeredo JL,Toda K,et al.Role of occlusal vertical dimension in spindle function[J].J Dent Res,2005,84(3):245-249.
[11]Mcnamara JA Jr,Bryan FA.Long-term mandibular adaptations to protrusive function:an experimental study in Macaca mulatta[J].Am J Orthod Dentofacial Orthop,1987,92(2):98-108.
[12]Kuboki T,Shinoda M,Orsini MG,et al.Viscoelastic properties of the pig temporomandibular joint articular soft tissues of the condyle and disc[J].J Dent Res,1997,76(11):1 760-1 769.