医院抗菌药物应用现状及影响分析
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摘要
抗菌药物的出现和发展对人类战胜各种感染性疾病有至关重要的作用。由于抗菌药物滥用所导致的细菌耐药性已成为世界各国和地区所关注的公共卫生难题。通过文献荟萃分析方法研究国内外细菌耐药性现状,了解和探讨抗菌药物不合理使用和细菌耐药性所引发的影响。
The emergence and development of antimicrobial agents play a vital role in the fight against all kinds of infectious diseases. The drug resistance caused by the abuse of antimicrobial agents has become a public health problem in the world. In this paper, we analyzed the current situation of bacterial resistance at home and abroad through metaanalysis to learn the status quo, the irrational use of antibiotics and the social impact caused by bacterial resistance.
The emergence and development of antimicrobial agents play a vital role in the fight against all kinds of infectious diseases. The drug resistance caused by the abuse of antimicrobial agents has become a public health problem in the world. In this paper, we analyzed the current situation of bacterial resistance at home and abroad through metaanalysis to learn the status quo, the irrational use of antibiotics and the social impact caused by bacterial resistance.
引文
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[22]马林,叶庆临,王兴华,等.抗菌药物使用合理性的调查与评价[J].现代预防医学,2002,29(4):562-564.
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[25]Elseviers M,Anna BA.Introduction to drug utilization research[M].Chichester:John Wiley&Sons,2016.
[26]段淑卿.抗菌药物规范化管理前后医院外科围手术期抗菌药物预防应用比较与分析[D].济南:山东大学,2013.
[27]王青,王育琴,李少丽,等.合理用药国际指标多中心干预研究[J].中国药学杂志,2002,37(3):233-235.
[2]张宏,马守江,刘振波,等.抗菌药物滥用与细菌耐药防控研究[J].临床合理用药杂志,2011,4(10):153-155.
[3]马越.合理利用抗生素资源,遏制细菌耐药性蔓延[J].中国药房,2011,22(26):2401-2403.
[4]赵健,李野.遏制抗菌药物滥用是药品监管的重要责任[J].中国药业,2004,13(12):4-5.
[5]张浩军,张映华,王燕,等.1453例住院患者抗菌药物临床应用回顾性调查分析[J].中华医院感染学杂志,2009,19(2):193-195.
[6]缪晓辉.抗菌药物临床应用中的问题与对策[J].中华医院管理杂志,2005,21(2):122-125.
[7]陈坚,方维军.上海市松江区21家医疗机构门诊处方合理用药国际指标调研[J].中国药房,2009,20(19):1517-1518.
[8]刘敬伟,甘霖,肖水源,等.2003-2009年102家医院住院患者抗菌药使用的趋势研究[J].中国全科医学,2011,14(1):102-104.
[9]董鹏,张立峰.普通外科480例住院患者抗菌药物应用情况分析[J].华西医学,2010,25(4):777-779.
[10]陈莹莹.行政干预前后抗菌药物临床应用分析[J].中华医院感染学杂志,2009,19(2):196-198.
[11]陈炜.抗菌药物综合干预管理的研究[J].中华医院感染学杂志,2007,17(10):1260-1262.
[12]冷萍,曹玉,丁海燕,等.住院患者抗菌药物的使用实施干预的调查研究[J].中华医院感染学杂志,2009,19(2):199-201.
[13]何新华,李春盛.抗生素滥用及其不良反应[J].中国临床医生,2005,33(2):11-12.
[14]王东辉.抗菌药临床不合理应用分析[D].济南:山东大学,2008.
[15]明星.湖北省县、乡两级医疗机构抗菌药物合理使用研究[D].武汉:华中科技大学,2008.
[16]肖永红,侯芳,王进,等.抗菌药物不良反应的社会与经济后果调查[J].中国卫生经济,2010,29(5):94-96.
[17]Dajani AS.Adherence to physician instructions as a factor in managing streptococcal pharyngitis[J].Pediatrics,1996,97(6):976-980.
[18]Sclar DA,Tartaglione TA,Fine MJ.Overview of issues related to medical compliance with implications for the outpatient management of infectious diseases[J].Infetc Agents Dis,1994,3(5):266-273.
[19]Guven GS,Uzun O.Principles of good use of antibiotics in hospitals[J].Journal of Hospital Infection,2003,53(2):91-96.
[20]Hecker MT,Aron DC,Patel NP,et al.Unnecessary use of antimicrobials in hospitalized patients:current patterns of misuse with an emphasis on the antianaerobic spectrum of activity[J].Archives of Internal Medicine,2003,163(8):972-978.
[21]陆权,陈慧中,杨永弘.制定与推广抗菌药物合理使用指南控制细菌耐药[J].中华儿科杂志,2002,53(8):458-460.
[22]马林,叶庆临,王兴华,等.抗菌药物使用合理性的调查与评价[J].现代预防医学,2002,29(4):562-564.
[23]Jim ON.Tacking drug-resistant infections globally:final report and recommendations[EB/OL].(2016-05-19)[2018-02-24].http://apo.org.au/node/63983.
[24]European Centre for Disease Prevention and Control.Antimicrobial resistance interactive database(EARS-NET)data for 2013[EB/OL].(2014-05-07)[2018-02-24].https://ecdc.europa.eu/en/antimicrobial-resistance.
[25]Elseviers M,Anna BA.Introduction to drug utilization research[M].Chichester:John Wiley&Sons,2016.
[26]段淑卿.抗菌药物规范化管理前后医院外科围手术期抗菌药物预防应用比较与分析[D].济南:山东大学,2013.
[27]王青,王育琴,李少丽,等.合理用药国际指标多中心干预研究[J].中国药学杂志,2002,37(3):233-235.