冠心病患者的尿微量白蛋白/肌酐值与其冠状动脉病变程度的相关性
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摘要
目的:探讨随机尿微量白蛋白/肌酐(U-malb/Ucr)值与冠心病患者冠状动脉病变程度的相关性。方法 :将2016年2月至2017年5月期间绵阳第三人民医院收治的100例冠心病患者和同期进行健康体检的50例健康人作为研究对象。将这100例患者分为A组(冠状动脉病变的程度≥50%)和B组(冠状动脉病变的程度<50%),将50例健康人作为C组。对三组研究对象均进行24 h随机尿定量检测,并根据检测结果找出U-malb/Ucr值与其冠状动脉病变程度的相关性。结果 :A组患者和B组患者的U-malb/Ucr值均高于C组健康人,差异有统计学意义(P<0.05)。A组患者的U-malb/Ucr值高于B组患者,差异有统计学意义(P<0.05)。对两组冠心病患者冠状动脉病变的程度和U-malb/Ucr值进行Logistic多元回归分析的结果显示:其冠状动脉病变的程度与其U-mAlb/Ucr值呈正相关。结论 :U-malb/Ucr值与冠心病患者冠状动脉病变的程度具有相关性。冠心病患者的U-malb/Ucr值越高则其冠状动脉病变的程度越重。因此,可将U-mAlb/Ucr值作为预测冠心病患者冠状动脉病变程度的主要指标。
Objective: To investigate correlation of coronary artery disease extension and U-malb/Ucr value of the patients with coronary heart disease. Methods: Select 100 cases of coronary artery disease accepting treatment and 50 cases of healthy people accepting physical examination in The Third People's Hospital of Mianyang city during February 2016 to May 2017 for research object.Divide the 100 patients to group A(Coronary artery disease extension ≥ 50 %) and group B(Coronary artery disease extension < 50%),set the 50 cases of 50 healthy people to group C. Randomly do ration urine detection in 24 hours to the 3 groups, to find correlation of Coronary artery disease extension and U-malb/Ucr of base on the test result. Results: The U-malb/Ucr value of group A and group B and was higher than that of group C(P <0.05).The result of Logistic multiple regression analysis shows that coronary artery disease extension is positively correlated with U-malb/Ucr value. Conclusion: There is a correlation between Coronary artery disease extension and U-malb/Ucr value. Higher U-malb/Ucr value is with higher severity of coronary artery disease extension. U-malb/Ucr value can be an important index to pre-diagnose coronary artery disease extension.
Objective: To investigate correlation of coronary artery disease extension and U-malb/Ucr value of the patients with coronary heart disease. Methods: Select 100 cases of coronary artery disease accepting treatment and 50 cases of healthy people accepting physical examination in The Third People's Hospital of Mianyang city during February 2016 to May 2017 for research object.Divide the 100 patients to group A(Coronary artery disease extension ≥ 50 %) and group B(Coronary artery disease extension < 50%),set the 50 cases of 50 healthy people to group C. Randomly do ration urine detection in 24 hours to the 3 groups, to find correlation of Coronary artery disease extension and U-malb/Ucr of base on the test result. Results: The U-malb/Ucr value of group A and group B and was higher than that of group C(P <0.05).The result of Logistic multiple regression analysis shows that coronary artery disease extension is positively correlated with U-malb/Ucr value. Conclusion: There is a correlation between Coronary artery disease extension and U-malb/Ucr value. Higher U-malb/Ucr value is with higher severity of coronary artery disease extension. U-malb/Ucr value can be an important index to pre-diagnose coronary artery disease extension.
引文
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[2]赵静,魏淑岩,李然,等.原发性高血压患者尿微量白蛋白和冠状动脉狭窄性病变程度的关系[J].现代生物医学进展,2014,14(23):4497-4500.
[3]谭学新.糖代谢异常患者肾功能损害与冠状动脉病变的关系[J].临床医学,2015,35(10):52-54.