癫痫患者认知障碍的影响因素及相关筛查量表
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摘要
癫痫是多种原因导致的脑部神经元高度同步化异常放电所致的临床综合征,是神经系统常见疾病。认知障碍是癫痫患者常见的伴随症状,在癫痫的整个病程中及时有效地评估患者认知功能,对抗癫痫药物的选择、改善患者预后有重要意义。本文结合相关文献,对癫痫患者认知功能的影响因素和常见认知功能评估量表做一个简单的概述,以期临床医师在诊治癫痫过程中定期进行认知功能监测,及时发现并重视癫痫患者认知功能异常,预防或尽量减少癫痫患者认知功能的损害,提高患者生存质量。
引文
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[23]MAKINEN J,RAINESALO S,RAITANEN J,et al.The effect of newer antiepileptic drugs in combination therapy[J].Epilepsy Res,2017,132:15-20.
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[26]史天涛,付培鑫,潘烨.韦氏智力测验的研究进展及其法医学应用价值[J].中国法医学杂志,2016,31(2):289-293.
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[29]王健邹,崔介峰.韦克斯勒记忆量表第四版中文版(成人版)的修订[J].中国心理卫生杂志,2015,29(1):53-59.
[30]BOUMAN Z,ELHORST D,HENDRIKS M P,et al.Clinical utility of the Wechsler Memory Scale-Fourth Edition(WMS-IV)in patients with intractable temporal lobe epilepsy[J].Epilepsy Behav,2016,55:178-182.
[31]张小斌,王逢鹏,王圆庆,等.中国修订韦氏记忆量表在颞叶内侧型癫痫术前评估中的应用[C].第七届CAAE国际癫痫论坛论文汇编,2017.
[32]GIOVAGNOLI A R,PARENTE A,TARALLO A,et al.Selfrated and assessed cognitive functions in epilepsy:Impact on quality of life[J].Epilepsy Res,2014,108(8):1461-1468.
[33]GIOVAGNOLI A R.Awareness,overestimation,and underestimation of cognitive functions in epilepsy[J].Epilepsy Behav,2013,26(1):75-80.
[34]李苗苗,高蕾,张小翠.中文版多元认知能力自评量表的信效度检验[J].中国康复医学杂志,2017,11(32):1236-1240.
[35]HELMSTAEDTER C,SCHOOF K,ROSSMANN T.Introduction and first validation of EpiTrack Junior,a screening tool for the assessment of cognitive side effects of antiepileptic medication on attention and executive functions in children and adolescents with epilepsy[J].Epilepsy Behav,2010,19(1):55-64.
[2]TRACIE A C,ROBERT J F,ROBERT M R,et al.A cognitive behavioral intervention(HOBSCOTCH)improves quality of life and attention in epilepsy[J].Epilepsy Behav,2016,57(PtA):111-117.
[3]TAI X Y,BERNHARDT B,THOM M,et al.Review:Neurodegenerative processes in temporal lobe epilepsy with hippocampal sclerosis:Clinical,pathological and neuroimaging evidence[J].Neuropathol Appl Neurobiol,2018,44(1):70-90.
[4]JENSEN E J,HARGREAVES I S,PEXMAN P M,et al.Abnormalities of lexical and semantic processingin left temporal lobe epilepsy:An fMRI study[J].Epilepsia,2011,52(11):2013-2021.
[5]LI J,CHEN X,YE W,et al.Alteration of the alertness-related network in patients with right temporal lobe epilepsy:A resting state fMRI study[J].Epilepsy Res,2016,127:252-259.
[6]BRAAKMAN H M H,VAESSEN M J,JANSEN J F A,et al.Aetiology of cognitive impairment in children with frontal lobe epilepsy[J].Acta Neurologica Scandinavica,2015,131(1):17-29.
[7]BOLY M,JONES B,FINDLAY G,et al.Altered sleep homeostasis correlates with cognitive impairment in patients with focal epilepsy[J].Brain,2017,140(4):1026-1040.
[8]WILSON S J,BAXENDALE S.Reprint of:The new approach to classification:Rethinking cognition and behavior in epilepsy[J].Epilepsy Behav,2016,64(Pt B):300-303.
[9]SIDHU M K,JASON S,WINSTON G P,et al.Memory fMRIpredicts verbal memory decline afteranterior temporal lobe resection[J].Neurology,2015,84(15):1512-1519.
[10]KRAMSK L,VOJTěCH Z,LUKAVSK J,et al.Five-year neuropsychological outcome after stereotactic radiofrequency amygdalohippocampectomy for mesial temporal lobe epilepsy:Longitudinal study[J].Stereotact Funct Neurosurg,2017,95(3):149-157.
[11]BREUER L E M,GREVERS E,BOON P,et al.Cognitive deterioration in adult epilepsy:clinical characteristics of"Accelerated Cognitive Ageing"[J].Acta Neurologica Scandinavica,2017,136(1):47-53.
[12]TAYLOR J,KOLAMUNNAGE-DONA R,MARSON A G,et al.Patients with epilepsy:Cognitively compromised before the start of antiepileptic drug treatment?[J].Epilepsia,2010,51(1):48-56.
[13]HESSEN E,LOSSIUS M I,GJERSTAD L.Improvement in verbal memory after withdrawal of carbamazepine and valproate in patients with well-controlled epilepsy:a randomized,doubleblind study[J].Acta Neurol Scand,2011,123(6):385-389.
[14]ELKJAER L S,BECH B H,SUN Y,et al.Association between prenatal valproate exposure and performance on standardized language and mathematics tests in school-aged children[J].JAMA Neurol,2018,75(6):663-671.
[15]INOYAMA K,MEADOR K J.Cognitive outcomes of prenatal antiepileptic drug exposure[J].Epilepsy Res,2015,114:89-97.
[16]GE Y X,TIAN X Z,LIN Y Y,et al.Chronic treatment with levetiracetam reverses deficits in hippocampal LTP in vivo in experimental temporal lobe epilepsy rats[J].Neurosci Lett,2016,628:194-200.
[17]STEVE S C,HOGAN R E,ILAN B,et al.Long-term safety and sustained efficacy of USL255(topiramate extended-release capsules)in patients with refractory partial-onset seizures[J].Epilepsy Behav,2016,59:13-20.
[18]WITT J A,ELGER C E,HELMSTAEDTER C.Impaired verbal fluency under topiramate-evidence forsynergistic negative effects of epilepsy,topiramate,and polytherapy[J].Eur J Neurol,2013,20(1):130-137.
[19]GULEC SUYEN G,ISBIL-BUYUKCOSKUN N,KAHVECI N,et al.Immediate and delayed treatment with gabapentin,carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats[J].Pharmacol Biochem Behav,2016,148:128-135.
[20]HELMSTAEDTER C,WITT J A.The longer-term cognitive effects of adjunctive antiepileptic treatment with lacosamide in comparison with lamotrigine and topiramate in a naturalistic outpatient setting[J].Epilepsy Behav,2013,26(2):182-187.
[21]MOAVERO R,PISANI L R,PISANI F,et al.Safety and tolerability profile of new antiepileptic drug treatment in children with epilepsy[J].Expert Opin Drug Saf,2018,17(10):1015-1028.
[22]VAN V T,IJFF D,ALDENKAMP A P,et al.Chronic antiepileptic drug use and functional network efficiency:A functional magnetic resonance imaging study[J].World J Radiol,2017,9(6):287-294.
[23]MAKINEN J,RAINESALO S,RAITANEN J,et al.The effect of newer antiepileptic drugs in combination therapy[J].Epilepsy Res,2017,132:15-20.
[24]CHARLOTTE S,EMILY L,GREGORY L,et al.Comparing safety and efficacy of"third-generation"antiepileptic drugs:long-term extension and post-marketing treatment[J].CNSDrugs,2017,31(11):959-974.
[25]韩健,尹琪华.蒙特利尔认知评估量表在癫痫认知功能障碍患者中的应用价值[J].中国临床神经科学,2013,21(1):75-80.
[26]史天涛,付培鑫,潘烨.韦氏智力测验的研究进展及其法医学应用价值[J].中国法医学杂志,2016,31(2):289-293.
[27]SHERMAN E M S,BROOKS B L,FAY-MCCLYMONT T B,et al.Detecting epilepsy-related cognitive problems in clinically referred children with epilepsy:Is the WISC-IV a useful tool?[J].Epilepsia,2012,53(6):1060-1066.
[28]HOELZLE J B,NELSON N W,SMITH C A.Comparison of Wechsler Memory Scale-Fourth Edition(WMS-IV)and Third Edition(WMS-III)dimensional structures:improved ability to evaluate auditory and visual constructs[J].J Clin Exp Neuropsychol,2011,33(3):283-291.
[29]王健邹,崔介峰.韦克斯勒记忆量表第四版中文版(成人版)的修订[J].中国心理卫生杂志,2015,29(1):53-59.
[30]BOUMAN Z,ELHORST D,HENDRIKS M P,et al.Clinical utility of the Wechsler Memory Scale-Fourth Edition(WMS-IV)in patients with intractable temporal lobe epilepsy[J].Epilepsy Behav,2016,55:178-182.
[31]张小斌,王逢鹏,王圆庆,等.中国修订韦氏记忆量表在颞叶内侧型癫痫术前评估中的应用[C].第七届CAAE国际癫痫论坛论文汇编,2017.
[32]GIOVAGNOLI A R,PARENTE A,TARALLO A,et al.Selfrated and assessed cognitive functions in epilepsy:Impact on quality of life[J].Epilepsy Res,2014,108(8):1461-1468.
[33]GIOVAGNOLI A R.Awareness,overestimation,and underestimation of cognitive functions in epilepsy[J].Epilepsy Behav,2013,26(1):75-80.
[34]李苗苗,高蕾,张小翠.中文版多元认知能力自评量表的信效度检验[J].中国康复医学杂志,2017,11(32):1236-1240.
[35]HELMSTAEDTER C,SCHOOF K,ROSSMANN T.Introduction and first validation of EpiTrack Junior,a screening tool for the assessment of cognitive side effects of antiepileptic medication on attention and executive functions in children and adolescents with epilepsy[J].Epilepsy Behav,2010,19(1):55-64.